■心肌梗死(MI),危急情况,严重影响患者预后和死亡率。长链非编码RNA(lncRNA)在MI的发病和进展中起关键作用。本研究旨在从文献计量学的角度探讨MI相关lncRNAs的相关研究,为该领域的研究人员提供新的线索和方向。
■于2023年8月7日进行了全面搜索,使用WebofScienceCoreCollection(WoSCC)数据库编译了所有英语科学期刊的数据集。该搜索收集了2000年1月至2023年8月与MI相关的lncRNA有关的所有相关出版物。国家数据,机构,期刊,作者,和关键字被收集,排序,统计分析,并使用CiteSpace6.2进行可视化。R4,VOSviewer1.6.19,一个在线文献计量分析平台(http://bibliometric.com),和R-Studio4.3.1中的文献计量包。文章由两名独立审稿人筛选。
■在2000年1月至2023年8月之间,在MI相关lncRNA的研究领域共发表了1,452篇论文。出版物最多的一年是2020年,占256篇论文。出版量呈指数增长趋势,拟合方程y=2.0215e0.2786x,R^2=0.97。在这个领域,中国在发表论文数量(N=1,034)和引用总数方面均领先,其次是美国,德国,伊朗,和意大利。最有生产力的机构是哈尔滨医科大学(N=144)。《欧洲医学和药理学评论》的出版物数量最多(N=46),而循环研究的引用次数最多(TC=4537),表明其在这一领域不可替代的地位。研究主要集中在心血管系统,细胞生物学,生理学,等。最有成效的作者是张勇。除了“心肌梗塞”和“LncRNA,“最常见的关键字包括”表达式,动脉粥样硬化,“和”凋亡。“聚类分析表明,当前的研究主题集中在心血管疾病和基因表达上,心脏缺血/再灌注损伤和保护,表达和增殖,动脉粥样硬化和炎症反应,在其他人中。关键词突发表明最近的热门话题是瞄准,自噬,等。
■此文献计量分析揭示,在2000年1月至2023年8月之间,对MI相关lncRNA的研究迅速扩展,主要由中国和美国领导。我们的研究强调了lncRNAs在MI的发病机制和进展中的重要生物学作用。包括它们参与基因表达调控,动脉粥样硬化的发展,和凋亡。这些发现强调了lncRNAs作为MI的治疗靶标和生物标志物的潜力。此外,我们的研究提供了相关出版物的特点和质量的见解,以及该研究领域未来的发展方向。前面还有很长的路要走,强调迫切需要加强全球学术交流。
UNASSIGNED: Myocardial infarction (MI), a critical condition, substantially affects patient outcomes and mortality rates. Long non-coding RNAs (lncRNAs) play a critical role in the onset and progression of MI. This study aimed to explore the related research on MI-related lncRNAs from a bibliometric perspective, providing new clues and directions for researchers in the field.
UNASSIGNED: A comprehensive search was conducted on 7 August 2023, using the Web of Science Core Collection (WoSCC) database to compile a dataset of all English-language scientific journals. The search gathered all relevant publications from January 2000 to August 2023 that pertain to MI-related lncRNAs. Data on countries, institutions, journals, authors, and keywords were collected, sorted, statistically analyzed, and visualized using CiteSpace 6.2.R4, VOSviewer 1.6.19, an online bibliometric analysis platform (http://bibliometric.com), and the bibliometric package in R-Studio 4.3.1. Articles were screened by two independent reviewers.
UNASSIGNED: Between January 2000 and August 2023, a total of 1,452 papers were published in the research field of MI-related lncRNAs. The year with the most publications was 2020, accounting for 256 papers. The publication volume displayed an exponential growth trend, fitting the equation y = 2.0215e0.2786x, R^2 = 0.97. In this domain, China leads in both the number of published papers (N = 1,034) and total citations, followed by the United States, Germany, Iran, and Italy. The most productive institution is Harbin Medical University (N = 144). The European Review for Medical and Pharmacological Sciences had the highest number of publications (N = 46), while Circulation Research had the most citations (TC = 4,537), indicating its irreplaceable standing in this field. Research mainly focuses on the cardiovascular system, cellular biology, physiology, etc. The most productive author is Zhang Y. Apart from \"Myocardial Infarction\" and \"LncRNA,\" the most frequent keywords include \"expression,\" \"atherosclerosis,\" and \"apoptosis.\" Cluster analysis suggests current research themes concentrate on cardiovascular diseases and gene expression, cardiac ischemia/reperfusion injury and protection, expression and proliferation, atherosclerosis and inflammatory response, among others. Keyword bursts indicate recent hot topics as targeting, autophagy, etc.
UNASSIGNED: This bibliometric analysis reveals that research on MI-related lncRNAs has rapidly expanded between January 2000 and August 2023, primarily led by China and the United States. Our study highlights the significant biological roles of lncRNAs in the pathogenesis and progression of MI, including their involvement in gene expression regulation, atherosclerosis development, and apoptosis. These findings underscore the potential of lncRNAs as therapeutic targets and biomarkers for MI. Additionally, our study provides insights into the features and quality of related publications, as well as the future directions in this research field. There is a long road ahead, highlighting the urgent need for enhanced global academic exchange.