背景:在COVID-19大流行期间,这项研究深入研究了呼吸机短缺,探索简单分离式通风(SSV),简单差动通风(SDV),和差分多元通气(DMV)。知识差距集中在了解他们的性能和安全影响。
目的:我们的假设假定SSV,SDV,和DMV为呼吸机危机提供解决方案。严格的测试有望揭示优势和局限性,帮助开发有效的通风方法。
■使用专门的试验台,SSV,SDV,和DMV进行了比较。在受控设置中的模拟肺促进了传感器的测量。统计分析对峰值吸气压力(PIP)和呼气末正压等参数进行了磨练。
结果:将目标PIP设定为肺1的15cmH2O和肺2的12.5cmH2O,SSV显示两个肺的PIP为15.67±0.2cmH2O,潮气量(Vt)为152.9±9mL。在SDV中,肺1的PIP为25.69±0.2cmH2O,肺2在24.73±0.2cmH2O,和464.3±0.9毫升和453.1±10毫升的Vts,分别。DMV试验显示肺1的PIP为13.97±0.06cmH2O,肺2在12.30±0.04cmH2O,Vts为125.8±0.004mL和104.4±0.003mL,分别。
结论:这项研究丰富了对呼吸机共享策略的理解,强调谨慎选择的必要性。车管所,提供个性化,同时保持电路连续性,站出来。研究结果为稳健的多路复用策略奠定了基础,在危机中加强呼吸机管理。
BACKGROUND: Amid the COVID-19 pandemic, this study delves into ventilator shortages, exploring simple split ventilation (SSV), simple differential ventilation (SDV), and differential multiventilation (DMV). The knowledge gap centers on understanding their performance and safety implications.
OBJECTIVE: Our hypothesis posits that SSV, SDV, and DMV offer solutions to the ventilator crisis. Rigorous testing was anticipated to unveil advantages and limitations, aiding the development of effective ventilation approaches.
UNASSIGNED: Using a specialized test bed, SSV, SDV, and DMV were compared. Simulated lungs in a controlled setting facilitated measurements with sensors. Statistical analysis honed in on parameters like peak inspiratory pressure (PIP) and positive end-expiratory pressure.
RESULTS: Setting target PIP at 15 cm H2O for lung 1 and 12.5 cm H2O for lung 2, SSV revealed a PIP of 15.67 ± 0.2 cm H2O for both lungs, with tidal volume (Vt) at 152.9 ± 9 mL. In SDV, lung 1 had a PIP of 25.69 ± 0.2 cm H2O, lung 2 at 24.73 ± 0.2 cm H2O, and Vts of 464.3 ± 0.9 mL and 453.1 ± 10 mL, respectively. DMV trials showed lung 1\'s PIP at 13.97 ± 0.06 cm H2O, lung 2 at 12.30 ± 0.04 cm H2O, with Vts of 125.8 ± 0.004 mL and 104.4 ± 0.003 mL, respectively.
CONCLUSIONS: This study enriches understanding of ventilator sharing strategy, emphasizing the need for careful selection. DMV, offering individualization while maintaining circuit continuity, stands out. Findings lay the foundation for robust multiplexing strategies, enhancing ventilator management in crises.