Ventilación

  • 文章类型: Journal Article
    背景:手术后肺部并发症(PPC)因不同的手术技术而异。我们旨在比较腹腔镜非机器人与腹腔镜机器人腹部手术后PPC的发生率。
    方法:LapRas(腹腔镜非机器人与腹腔镜机器人腹部手术中PPCs的危险因素)结合了来自2项关于腹部手术患者和PPCs的观察性研究的统一数据:“全身麻醉手术期间VEntitlatory管理的局部评估”(LASVEGAS),和“机器人手术全身麻醉期间的通气评估”(AVATaR)。主要终点是在术后前五天出现一个或多个PPC。次要终点包括每个PPC的发生,住院时间和住院死亡率。Logistic回归模型将用于确定腹腔镜非机器人与腹腔镜机器人腹部手术中PPC的危险因素。我们将调查两组之间PPC发生率的差异是否由麻醉持续时间和/或机械通气强度的差异驱动。
    背景:该分析将解决比较腹腔镜和机器人辅助手术的临床相关研究问题。此元分析不需要额外的道德委员会批准。数据将通过提交给同行评审期刊的摘要和原始文章与科学界共享。
    背景:此事后分析的注册正在等待中;合并到已使用数据库中的个别研究已在clinicaltrials.gov:LASVEGAS上注册,标识符为NCT01601223,标识符为NCT02989415。
    BACKGROUND: Postoperative pulmonary complications (PPCs) vary amongst different surgical techniques. We aim to compare the incidence of PPCs after laparoscopic non-robotic versus laparoscopic robotic abdominal surgery.
    METHODS: LapRas (Risk Factors for PPCs in Laparoscopic Non-robotic vs Laparoscopic robotic abdominal surgery) incorporates harmonized data from 2 observational studies on abdominal surgery patients and PPCs: \'Local ASsessment of VEntilatory management during General Anaesthesia for Surgery\' (LAS VEGAS), and \'Assessment of Ventilation during general AnesThesia for Robotic surgery\' (AVATaR). The primary endpoint is the occurrence of one or more PPCs in the first five postoperative days. Secondary endpoints include the occurrence of each individual PPC, hospital length of stay and in-hospital mortality. Logistic regression models will be used to identify risk factors for PPCs in laparoscopic non-robotic versus laparoscopic robotic abdominal surgery. We will investigate whether differences in the occurrence of PPCs between the two groups are driven by differences in duration of anesthesia and/or the intensity of mechanical ventilation.
    BACKGROUND: This analysis will address a clinically relevant research question comparing laparoscopic and robotic assisted surgery. No additional ethical committee approval is required for this metanalysis. Data will be shared with the scientific community by abstracts and original articles submitted to peer-reviewed journals.
    BACKGROUND: The registration of this post-hoc analysis is pending; individual studies that were merged into the used database were registered at clinicaltrials.gov: LAS VEGAS with identifier NCT01601223, AVATaR with identifier NCT02989415.
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  • 文章类型: Journal Article
    背景:半毛脂体(LS)的临床表现各不相同,诊断标准不明确。几种致病因素,包括职业环境,有人建议。我们旨在描述一系列疑似LS的病例,这些病例于2008年5月开始出现在马德里市议会的雇员中,西班牙。我们报告了理事会职业健康服务部门采取的行动,并提出了具有预后意义的临床类别。
    方法:回顾性观察性病例系列研究,包括2008年至2021年在马德里市议会STI/皮肤科评估的患者的前瞻性收集数据。有关职业卫生服务处采取的措施的信息很详细。记录用于统计分析的临床变量并提出定义的临床模式。
    结果:我们研究了75名女性和1名男性的病例,其中大多数人参加了平均37个月的随访。仅14.5%的患者出现局部症状。将病例分为4组:典型LS,单边LS,下肢带状脂肪萎缩,非特异性LS。前两组的临床结果通常更有利,其中76%的患者实现了病变的全部或部分改善(与后2组25.8%)。LS与肥厚性皮下脂肪组织的存在呈负相关(P<.001)。
    结论:典型LS,这通常是单方面的,总体上有一个令人满意的结果。这种形式的临床特征将其与其他类型的脂肪萎缩区分开来。职业卫生服务处采取的措施有助于取得有利的结果。在这个系列中,LS与大腿明显的皮下脂肪组织肥大无关。我们提出的分类可能有助于区分预后良好的LS病例和其他表现为皮肤表面凹陷的病例。这往往是持久的。
    BACKGROUND: The clinical presentations of Lipoatrophia semicircularis (LS) vary, and diagnostic criteria are unclear. Several etiopathogenic factors, including occupational environmental ones, have been suggested. We aimed to describe a cluster of cases of suspected LS that started to appear in May 2008 among employees of the city council of Madrid, Spain. We report the actions taken by the council\'s Occupational Health Service and propose clinical categories with prognostic implications.
    METHODS: Retrospective observational case series study including prospectively collected data from patients evaluated between 2008 and 2021 at the Madrid City Council STI/Dermatology Department. Information on measures taken by the Occupational Health Service is detailed. The recording of clinical variables for statistical analysis and the proposal of defined clinical patterns were carried out.
    RESULTS: We studied the cases of 75 women and one man, most of whom attended follow-up visits for a median of 37 months. Local symptoms were observed in just 14.5% of patients. The cases were classified into 4 groups: typical LS, unilateral LS, band-like lipoatrophy in the lower limbs, and nonspecific LS. Clinical outcomes were more often favorable in the first 2 groups, in which 76% of patients achieved total or partial improvement of lesions (vs. 25.8% in the last 2 groups). LS was negatively associated with the presence of hypertrophic subcutaneous adipose tissue (P < .001).
    CONCLUSIONS: Typical LS, which can often be unilateral, generally has a satisfactory outcome. The clinical characteristics of this form distinguish it from other types of lipoatrophy. Measures taken by the Occupational Health Service contributed to favorable outcomes. In this series, LS was not associated with marked subcutaneous adipose tissue hypertrophy in the thighs. Our proposed categories may help distinguish between cases of LS with a favorable prognosis and other cases presenting with skin surface depressions, which are often persistent.
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  • 文章类型: Journal Article
    目的:半圆形脂肪萎缩(SL)的临床表现各不相同,诊断标准不明确。几种致病因素,包括职业环境,有人建议。我们的目的是描述一系列可疑的SL案件,这些案件于2008年5月开始出现在马德里市议会的雇员中,西班牙。我们报告了理事会职业卫生服务部门采取的行动,并提出了具有预后意义的临床类别。
    方法:回顾性确定患者的观察性研究,包括前瞻性收集的病例数据。2008年至2021年之间的病例被确定为由市议会的皮肤病学和预防性传播感染服务进行审查。对职业卫生服务部门采取措施的信息和临床数据进行了分析,以进行描述性统计和临床模式的检测,以帮助进行分类。
    结果:我们研究了75名女性和1名男性的病例,其中大多数人参加了平均37个月的随访。仅14.5%的患者出现局部症状。将病例分为4组:典型SL,单边SL,下肢带状脂肪萎缩,和非特异性SL。前两组的临床结果通常更有利,其中76%的患者实现了病变的全部或部分改善(与后2组25.8%)。SL与肥厚性皮下脂肪组织的存在呈负相关(P<.001)。
    结论:典型SL,这通常是单方面的,总体上有一个令人满意的结果。这种形式的临床特征将其与其他类型的脂肪萎缩区分开来。职业卫生服务部门采取的措施有助于取得有利的结果。在这个系列中,SL与大腿明显的皮下脂肪组织肥大无关。我们提出的类别可能有助于区分预后良好的SL病例和其他SL类型,其中皮肤表面凹陷形成且通常持续存在。
    OBJECTIVE: The clinical presentations of semicircular lipoatrophy (SL) vary, and diagnostic criteria are unclear. Several etiopathogenic factors, including occupational environmental ones, have been suggested. We aimed to describe a cluster of cases of suspected SL that started to appear in May 2008 among employees of the city council of Madrid, Spain. We report the actions taken by the council\'s occupational health service and propose clinical categories with prognostic implications.
    METHODS: Observational study of retrospectively identified patients that includes prospectively collected case data. Cases between 2008 and 2021 were identified for review by the city council\'s service for dermatology and prevention of sexually transmitted infections. Information on measures taken by the occupational health service and clinical data were analyzed for descriptive statistics and detection of clinical patterns to aid classification.
    RESULTS: We studied the cases of 75 women and 1 man, most of whom attended follow-up visits for a median of 37 months. Local symptoms were observed in just 14.5% of patients. The cases were classified into 4 groups: typical SL, unilateral SL, band-like lipoatrophy in the lower limbs, and nonspecific SL. Clinical outcomes were more often favorable in the first 2 groups, in which 76% of patients achieved total or partial improvement of lesions (vs. 25.8% in the last 2 groups). SL was negatively associated with the presence of hypertrophic subcutaneous adipose tissue (P < .001).
    CONCLUSIONS: Typical SL, which can often be unilateral, generally has a satisfactory outcome. The clinical characteristics of this form distinguish it from other types of lipoatrophy. Measures taken by the occupational health service contributed to favorable outcomes. In this series, SL was not associated with marked subcutaneous adipose tissue hypertrophy in the thighs. Our proposed categories may help distinguish between cases of SL with a favorable prognosis and other SL types in which skin surface depressions form and are often persistent.
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  • 文章类型: Journal Article
    BACKGROUND: Supraglottic airways, which are easily inserted and minimize interruptions in cardiopulmonary resuscitation manoeuvres, are now widely used in pre- and in-hospital emergencies. However, most studies in these devices do not specify whether they ensure good ventilation during CPR. This systematic review aims to determine whether there is evidence that supraglotic airways enable effective ventilation during resuscitation.
    METHODS: The MEDLINE and COCHRANE databases were searched for studies published in English up to 30 November 2018. Eligible studies were all those that objectively evaluated tidal volume during resuscitation maneuvers in patients over 18 years of age using various supraglottic airways.
    RESULTS: A total of 3734 articles were identified, of which 252 were duplicates. Only 1 objectively evaluated ventilation during resuscitation maneuvers and presented data relevant to this review. The study included 470 patients, 51 of which underwent spirometry. Only 4.48% of patients survived to hospital discharge; however, the correlation with ventilation effectiveness was not assessed.
    CONCLUSIONS: There is no scientific evidence that supraglottic airways provide effective ventilation during resuscitation maneuvers. Evaluation by spirometry, chest impedance and ultrasound may help to determine the ventilatory efficacy of supraglottic airways during CPR, and clarify whether this factor contributes to the difficulties experienced in reversing cardiorespiratory arrest.
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  • 文章类型: Journal Article
    OBJECTIVE: Octogenarians undergo anatomic and physiopathologic degradation, making airway management problematic, specific to intubation, bag mask ventilation, leading to desaturation and aspiration. Our study\'s aim was to examine the process of airway management regarding the steps involved in intubation and any deviations or delays in the tasks.
    METHODS: An institutional review board-approved difficult airway prospective observational study in older adults was conducted. Inclusion criteria included airway features indicative of difficult airway, history of failed intubation, the planned use of specialized airway devices, and/or expected airway complications due to comorbidities. Patients 80 years and older were analyzed. Demographic data collected were age, weight, BMI, gender, ASA classification, airway indices, diagnosis, and procedures. Problems with intubation (INT) (≥3 intubation attempts), laborious assisted ventilation (VEN) (2-person and/or application of CPAP>20cmH2O), and complications with oxygenation (OXY) (SpO2<95%) were analyzed.
    RESULTS: Of the 41 patients enrolled in the study, 3 (7.3%) had all 3: problematic (INT), laborious (VEN), and desaturated (OXY); 8 (19.5%) patients experienced problematic (INT), 20 (48.8%) were described as laborious (VEN), and 14 (34.1%) experienced complications with (OXY).
    CONCLUSIONS: In octogenarians, we found a low incidence of difficulty with INT-VEN-OXY together. However, bag mask ventilation was found to be laborious with a high incidence of desaturation. Success rate of INT as a sole metric may not accurately describe the process of the intubation. We recommend alternative airway devices and techniques and the establishment of protocols for airway management in the elderly.
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  • 文章类型: Journal Article
    目的:描述西班牙毁灭性脑损伤患者器官捐献相关的临终护理实践。
    方法:回顾性队列的多中心前瞻性研究。
    方法:2014年11月1日至2015年4月30日。
    方法:获得器官采购授权的68家医院。
    方法:死于毁灭性脑损伤的患者(可能的供体)。年龄:1个月-85岁。
    方法:护理类型,脑死亡后的捐赠,循环系统死亡后的捐赠,插管/通气,转交给捐助者协调员。
    结果:总共确定了1,970个可能的捐献者,其中一半在重症监护病房(ICU)接受积极治疗,直到脑死亡(27%),心脏骤停(5%)或停止维持生命治疗(19%)。其余的,10%的人被送进ICU以方便器官捐献,而39%没有入住ICU。在那些演变成脑死亡状况的患者中(n=695),大多数过渡到实际捐赠(n=446;64%)。在退出维持生命治疗后死亡的人中(n=537),循环死亡捐献者后,有45人(8%)转化为实际捐赠。循环系统死亡计划后缺乏专门的捐赠是不捐赠的主要原因。37%的可能捐献者在死亡时没有插管/通气,主要是因为主管专业人员没有考虑捐赠改变丢弃治疗性插管。36%的可能捐助者从未被推荐给捐助者协调员。
    结论:尽管西班牙对死者的捐赠进行了优化,在ICU以外的可能供体的识别方面,以及在停药维持生命治疗后死亡的患者循环死亡后的捐献考虑方面,仍有改善的机会.
    OBJECTIVE: To describe end-of-life care practices relevant to organ donation in patients with devastating brain injury in Spain.
    METHODS: A multicenter prospective study of a retrospective cohort.
    METHODS: 1 November 2014 to 30 April 2015.
    METHODS: Sixty-eight hospitals authorized for organ procurement.
    METHODS: Patients dying from devastating brain injury (possible donors). Age: 1 month-85 years.
    METHODS: Type of care, donation after brain death, donation after circulatory death, intubation/ventilation, referral to the donor coordinator.
    RESULTS: A total of 1,970 possible donors were identified, of which half received active treatment in an Intensive Care Unit (ICU) until brain death (27%), cardiac arrest (5%) or the withdrawal of life-sustaining therapy (19%). Of the rest, 10% were admitted to the ICU to facilitate organ donation, while 39% were not admitted to the ICU. Of those patients who evolved to a brain death condition (n=695), most transitioned to actual donation (n=446; 64%). Of those who died following the withdrawal of life-sustaining therapy (n=537), 45 (8%) were converted into actual donation after circulatory death donors. The lack of a dedicated donation after circulatory death program was the main reason for non-donation. Thirty-seven percent of the possible donors were not intubated/ventilated at death, mainly because the professional in charge did not consider donation alter discarding therapeutic intubation. Thirty-six percent of the possible donors were never referred to the donor coordinator.
    CONCLUSIONS: Although deceased donation is optimized in Spain, there are still opportunities for improvement in the identification of possible donors outside the ICU and in the consideration of donation after circulatory death in patients who die following the withdrawal of life-sustaining therapy.
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  • 文章类型: Journal Article
    Acute heart failure is a major and growing public health problem worldwide with high morbidity, mortality, and cost. Despite recent advances in pharmacological management, the prognosis of patients with acute decompensated heart failure remains poor. Consequently, nonpharmacological approaches are being developed and increasingly used. Such techniques may include several modalities of ventilation, ultrafiltration, mechanical circulatory support, myocardial revascularization, and surgical treatment, among others. This document reviews the nonpharmacological approach in acute heart failure, indications, and prognostic implications.
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  • 文章类型: Comparative Study
    OBJECTIVE: The literature highlights the lack of noninvasive ventilation (NIV) protocols and the variability of the knowledge of NIV between intensive care units (ICU) and hospitals, so we want to compare NIV nurses\'s Knowledge from 4 multipurpose ICU and one surgical ICU.
    METHODS: Multicenter, crosscutting, descriptive study in three university hospitals. The survey instrument was validated in a pilot test, and the calculated Kappa index was 0.9. Returning a completed survey is an indication of informed consent. Analysis by Chi square test.
    RESULTS: 117 responded (65%) nurses, 11±9.7 years of experience in ICU and 9.2±7.2 in use of NIV. One of the multipurpose ICU, was initiated NIV an average of 6 years later than the others (95% CI [3.3 to 8.6], P<.001). Only 23.1% of nurses would place a non-vented mask (with no exhalation port) by conventional ventilator, the rest any kind of face mask. 12.7% believed that the mask must be adjusted to the \"2-finger\" fit while 29% would seal the mask to the patient\'s face and cover the mask opening where air escapes to facilitate patient/ventilator synchronization. In the surgical ICU agitation identifies mostly as a complication of NIV compared with multipurpose UCIs (31.6% vs 1.8%, P<.001). 56.4% of nurses do not consider respiratory physiotherapy as nursing care, with no difference between units.
    CONCLUSIONS: Knowledge about types of interface is very dependent on the material of the unit. More training for complications of NIV as agitation and handling secretions it is necessary.
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  • 文章类型: English Abstract
    OBJECTIVE: To describe chlorine levels in the air of indoor swimming pools in Castilla-La Mancha (Spain) and relate them to other chemical parameters in the installation and to the health problems perceived by swimming pool workers.
    METHODS: We analyzed 21 pools with chlorine as chemical treatment in Castilla-La Mancha. The iodometry method was applied to measure chlorine concentrations in the air. The concentrations of free and combined chlorine in water, pH and temperature were also evaluated. Health problems were surveyed in 230 swimming pool workers in these facilities.
    RESULTS: The mean chlorine level in the air of swimming pools was 4.3 ± 2.3mg/m(3). The pH values were within the legal limits. The temperature parameters did not comply with regulations in 17 of the 21 pools analyzed. In the pools where chlorine values in the air were above the legal regulations, a significantly higher percentage of swimming pool workers perceived eye irritation, dryness and irritation of skin, and ear problems.
    CONCLUSIONS: Chlorine values in the air of indoor swimming pools were higher than those reported in similar studies. Most of the facilities (85%) exceeded the concentration of 1.5mg/m(3) established as the limit for the risk of irritating effects. The concentration of chlorine in indoor swimming pool air has a direct effect on the self-perceived health problems of swimming pool workers.
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