背景:探索无针麻醉的途径引起了对离子电渗技术的特别关注。离子电渗疗法在牙科领域有广泛的应用,治疗超敏反应,口腔溃疡,深度局部麻醉的非侵入性程序,等。因此,本研究的目的是对5~12岁患者通过离子电渗注入局部麻醉喷雾和局部麻醉(LA)浸润进行牙科手术的对比评估.
方法:张口,在5~12岁的研究对象中进行了为期两年的随机临床试验.他们被随机分配到两组中的一组:第一组(A组-离子电渗疗法组)接受局部麻醉喷雾(Lidayn®;Pyrax聚合物,Roorkee,印度)通过离子电渗疗法应用,第二个(B组-LA浸润组)接受2%利多卡因溶液的局部浸润(LignoTer®;LusturePharma,Ahmedabad,印度),进行乳牙拔除或牙髓切除术。麻醉后立即使用Wong-Baker面部疼痛评定量表(WBFPRS)进行主观评估。
结果:提取过程的电流强度平均值为9.43±0.95mA,施用时间为1.85±0.80分钟。牙髓切除术的电流强度平均值为9.07±1.34mA,时间为2.40±0.74分钟。在组间比较中,A组WBFPRS评分(1.96±1.64)低于B组(3.62±1.11),具有统计学意义,p=0.001。
结论:与局部浸润相比,离子电渗疗法作为一种非侵入性的局部麻醉方法在儿科患者中更受欢迎。
BACKGROUND: Exploring routes of needle-free anesthesia has drawn particular attention to the iontophoretic technique. Iontophoresis has a wide range of applications in dentistry, treating hypersensitivity, oral ulcers, non-invasive procedures of deep topical anesthesia, etc. Hence, this research was performed for a comparative assessment of topical anesthesia spray infused via iontophoresis and local anesthesia (LA) infiltration for dental procedures among 5-12-year-old patients.
METHODS: A split-mouth, randomized clinical trial was undertaken over two years among study subjects aged 5 to 12 years. They were randomly assigned to one of two groups: the first (Group A - iontophoresis group) received topical anesthesia spray (Lidayn®; Pyrax Polymers, Roorkee, India) applied by iontophoresis, and the second (Group B - LA infiltration group) received local infiltration of 2% lignocaine solution (LignoTer®; Lusture Pharma, Ahmedabad, India), where primary teeth extraction or pulpectomy was performed. The Wong-Baker Facial Pain Rating Scale (WBFPRS) was used for a subjective assessment immediately following anesthesia.
RESULTS: The mean value of current intensity for the extraction procedure was 9.43±0.95 mA, and the duration of application was 1.85±0.80 minutes. The mean value of current intensity for pulpectomy was 9.07±1.34 mA, and the time was 2.40±0.74 minutes. In inter-group comparison, WBFPRS scores were lower in Group A (1.96±1.64) compared to Group B (3.62±1.11), which was statistically significant with p=0.001.
CONCLUSIONS: Compared to local infiltration, iontophoresis as a non-invasive approach for topical anesthesia was more well-received by pediatric patients.