As a result of the spontaneous movement of molecules, liquid-liquid biopolymer segregative phase separation takes place in an aqueous solution. The efficacy of this type of separation can be optimized under conditions where variables such as pH, temperature, and molecular concentrations have minimal impact on its dynamics. Recently, interest in the applications of biopolymers and their segregative phase separation-associated molecular stratification has increased, particularly in the food industry, where these methods permit the purification of specific particles and the embedding of microcapsules. The present review offers a comprehensive examination of the theoretical mechanisms that regulate the liquid-liquid biopolymers aqueous solution segregative phase separation, the factors that may exert an impact on this procedure, and the importance of this particular separation method in the context of food science. These discussion points also address existing difficulties and future possibilities related to the use of segregative phase separation in food applications. This highlights the potential for the design of novel functional foods and the enhancement of food properties.

The most common subtype of lung cancer is non-small cell lung cancer (NSCLC), which has a poor prognosis and seriously threatens the health of human beings. The multidisciplinary comprehensive treatment model has gradually become the mainstream of NSCLC treatment. Traditional Chinese medicine (TCM) can be used effectively either as an adjunctive therapy or alone throughout the NSCLC therapy, which has a significant impact on survival, quality of life, and reduction of toxicity. Therefore, this paper reviewed the theoretical basis, the latest clinical application, and combined treatment mechanisms in order to explore the advantage stage of TCM treatment and the synergistic therapeutic mechanisms.

School dropout may have important negative consequences for the individual as well as for society. It is therefore important to help students stay in school. Group interventions have been developed to reduce dropout, but the theoretical underpinnings of such programs are not always obvious. This study focuses on the Norwegian dropout-prevention program named \'Guttas Campus\' (The Boys\' Camp). We draw on published and unpublished research, other sources of written information, discussions with stakeholders, and direct observation of the intervention, to identify central theories that form the basis of the intervention. These theories are briefly presented, and the impact of the ideas on the intervention is analysed.

Human adipose-derived stem cells (hASCs) play an important role in regenerative medicine.
Exploring the mechanism of Rg1 in the promotion of the proliferation and adipogenic differentiation of hASCs is important in regenerative medicine research.
To observe ginsenoside Rg1 in promoting the proliferation and adipogenic differentiation of hASCs, Rg1 medium at different concentrations was established and tested using the cell counting kit-8 (CCK-8) assay, oil red O staining, alizarin red, and alcian blue. Compared to the control, differentially expressed genes (DEGs) were screened via DEG analysis, which was carried out in the Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analyses. To explore the relationship among mRNA, long non-coding RNA (lncRNA) and microRNA (miRNA), we constructed a competing endogenous RNA (ceRNA) network.
In this study, Rg1 was observed to promote the proliferation and adipogenic differentiation of hASCs. Additionally, enriched BPs and KEGG pathways may be involved in the promotion process, where FXR1 and Lnc-GAS5-AS1 were found to be regulatory factors. The regulatory network suggested that Rg1 could regulate the adipocytokine signaling pathway and IL-17 signaling pathway via FXR1 and Lnc-GAS5-AS1, which served as the mechanism encompassing the promotion of Rg1 on the proliferation and adipogenic differentiation of hASCs.
A comprehensive transcriptional regulatory network related to the promotion ability of Rg1 was constructed, revealing mechanisms regarding Rg1\'s promotion of the proliferation and adipogenic differentiation of hASCs. The present study provides a theoretical basis for optimizing the function of hASCs.

High Velocity Compaction (HVC) is a key technology to realize the performance of powder metallurgy parts \"three high and one low\" (high density, high precision, high performance, and low cost). The main purpose of this paper is to summarize the research results at home and abroad on the forming mechanism, forming influencing factors and theoretical basis of high velocity compaction. This paper analyzes and summarizes the literature and monographs at home and abroad through literature research methods to obtain the research results of high velocity powder metallurgy compaction, so as to fully and correctly understand the research progress, development trends and application prospects of high velocity compaction. This paper expounds the technical characteristics, advantages and limitations of high velocity compaction, and analyzes and looks forward to its development trend, application prospect and expansion field, So as to provide reference and reference for the future research and application direction of high velocity compaction technology.

Large-scale terrestrial ecosystem science research becomes an important research field with the promotion of meeting the scientific demand of biodiversity conservation, global climate change mitigation, regional eco-environment governance, and social sustainable development. It is developing rapidly under the guidance of China\'s ecological civilization construction strategy. Here, we systematically discussed the missions, theoretical foundation and methodology of large-scale terrestrial ecosystem science research and proposed a new theoretical foundation, conceptual system and logical framework for macroecosystem science research on the basis of macrosystem ecology theory. It elaborated the discipline connotation and application of the macroecosystem science to 1) deve-lop the conceptual network of ecosystem science based on the systematic characteristics of ecosystems; 2) develop the theoretical system of ecosystem state change analysis based on the ecosystem integrity and emergence characteristics; 3) develop the theoretical system of integrated research for ecosystem structure-process-function-service cascade relationship based on the attributes and state of ecosystems. We also discussed the methodology and technical system of regional and continental macroecosystem science research, and highlighted the urgency to construct a new generation of continental ecosystem observation and research network, and to develop the network observation-network experiment-numerical simulation-knowledge fusion four-in-one infrastructures.
大尺度的陆地生态系统科学研究是在生物多样性保护、应对全球气候变化、区域生态环境治理及全球社会经济可持续发展的科技需求背景下应运而生的生态学及生态系统科学前沿领域,并在我国的生态文明建设社会实践中快速发展。本文在系统论述大尺度陆地生态系统科学研究的科技使命基础上,重点梳理和探讨了区域及大陆尺度的生态系统科学研究理论基础和方法学问题,进而基于宏生态系统生态学理论,新提出了宏观生态系统科学的基础理论、科学概念及其研究方法体系的逻辑框架。本文重点探讨了: 1) 基于生态系统的系统学特性,发展多维视角的“生态系统科学概念网络体系”;2) 基于生态系统整体性和涌现性理论,发展“生态系统状态变化分析理论体系”;3) 基于生态系统属性及状态概念,发展生态系统结构-过程-功能-服务级联关系的“整合研究方法学理论体系”的学科内涵及应用问题,进而论述了发展区域及大陆尺度宏观生态系统科学研究的方法体系,提出构建新一代大陆尺度生态系统观测研究实验网络,完善“联网观测-联网实验-数值模拟-知识融合”四位一体的科学研究技术体系的必要性。.

In traditional Chinese medicine, the well-known saying that \"in the treatment of disorders of the orofacial region, Hegu(LI4)is usually taken\" is a highly summary of functions of acupoint LI4, the Yuan-primary point of the Large Intestine Meridian of Hand Yangming. By consulting the related literature and viewing from the angle of differentiation of meridians, the present paper expounded the characteristics of location, the attributed meridian and clinical functions of LI4, and summarized its underlying mechanisms in the treatment of some orofacial disorders revealed by experimental researches. In addition, some examples of clinical application of LI4 were listed, including peripheral facial palsy, oral diseases, problems of the nose and headache.
“面口合谷收”是医疗实践过程中对合谷治疗口面部疾病功效的高度总结。笔者查阅相关文献，从中医经络辨证角度出发，结合现代医学对其生理机制的研究，探讨支撑其证治规律的理论实质；同时对临床运用合谷穴治疗口面部疾病的报道进行举案归纳，浅析“面口合谷收”的理论基础与临床运用。.

The Corona Virus Disease 2019 (COVID-19) is an acute respiratory infectious disease. At present, COVID-19 has no specific therapeutic drugs, and the main clinical treatment is symptomatic treatment and control of complications. On March 5, 2020, the National Health Commission of the People\'s Republic of China issued the Guidelines for the Diagnosis and Treatment of Novel Coronavirus (2019-nCoV) Infection (Trial Version 7), which integrated traditional Chinese medicine (TCM) into the treatment of COVID-19. The purpose of this study is to summarize recent studies on the clinic application, pharmacological action, chemical substances and mechanism of Qingwen Baidu Decoction (QBD) on the treatment of various diseases. The results suggested that QBD has multiple pharmacological effects such as anti-inflammation, antiviral, antibacterial, immunomodulatory, antipyretic and so on. It has been used in the treatment of sepsis, epidemic hemorrhagic fever, epidemic cerebrospinal meningitis, infantile pneumonia, sepsis-related encephalopathy, epidemic encephalitis B and other diseases. In addition, this study attempts to explore the possible mechanism of QBD in the prevention and treatment of COVID-19. Through the analysis of the chemical substances, pharmacological action and mechanism of QBD, this paper will provide a reference theoretical basis for the prevention and treatment of COVID-19 by QBD.

To explore the mechanism of the pore formation in the laser-welded vacuum plate glazing sealing layer, a vacuum plate glazing laser side sealing test was carried out. The influence of the pulse current, pulse duration time, pulse frequency and welding speed on the pores of the sealing layer was studied by means of scanning electron microscopy (SEM) and metallographic microscopy, and the cause of the pores is analyzed. The results show that the porosity decreases with the increase of the pulse current. When the pulse current is 160 A, the pores are the fewest and smallest, and the porosity is only 0.1%. The porosity of the sealing layer decreases first and then increases with the increase of the pulse duration time. The porosity decreases first and then increases with the increase of the pulse frequency. When the pulse frequency is 18 Hz, the porosity is the least, at only 0.08%. The porosity of the sealing layer increases with the increase of the welding speed. When the welding speed is 80, 90, 100 and 110 mm/min, the porosity is 0.02, 0.08, 0.63 and 0.89%, respectively. These studies can provide a theoretical basis for laser sealing manufacturing of vacuum plate glazing.

In the guidance of preventive treatment, taking \"consolidation and non-obstruction\" as the core, emphasizing the importance of the antipathogenic qi in the treatment, the method of \"biaoben acupoint combination\" was proposed in acupuncture therapy. In the paper, the theoretic basis and the connotation of \"biaoben acupoint combination\", the application of the key acupoint combination and the study on cardiovascular system, digestive system and immune system were introduced and it was anticipated to provide the theoretic evidences for the acupoint selection and enrich the contents of acupoint combination in acupuncture.