Tenosynovitis

腱鞘炎
  • 文章类型: Journal Article
    银屑病关节炎(PsA)是一种与银屑病相关的慢性炎症性关节炎,以异质性临床表现和多变的疾病进展为特征。超声检查已成为诊断和监测PsA的有价值的工具。提供关节和软组织异常的实时可视化。这篇综述强调了超声检查技术在评估PsA方面的最新进展,包括典型特征的识别,能量多普勒成像在检测活动性炎症中的作用,以及超声指导治疗决策的潜力。此外,我们讨论了超声在评估PsA患者的治疗反应和监测疾病进展中的实用性,专注于新颖的成像方式。通过阐明超声检查在PsA管理中不断发展的作用,本文旨在提高临床医生对其在促进早期诊断方面的效用的理解,优化治疗策略,改善患者预后。
    Psoriatic arthritis (PsA) is a chronic inflammatory arthritis associated with psoriasis, characterized by heterogeneous clinical manifestations and variable disease progression. Ultrasonography has emerged as a valuable tool in the diagnosis and monitoring of PsA, providing real-time visualization of joint and soft tissue abnormalities. This review highlights recent advancements in ultrasonographic techniques for the assessment of PsA, including the identification of typical features, the role of power Doppler imaging in detecting active inflammation, and the potential of ultrasound for guiding treatment decisions. Additionally, we discuss the utility of ultrasound in assessing treatment response and monitoring disease progression in patients with PsA, with a focus on novel imaging modalities. By elucidating the evolving role of ultrasonography in PsA management, this article aims to enhance clinicians\' understanding of its utility in facilitating early diagnosis, optimizing treatment strategies, and improving patient outcomes.
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    文章类型: Case Reports
    背景:我们报告了孤立的第四伸肌室腱鞘炎病例,没有证据表明在COVID-19流行导致工作环境改变的背景下发生了全身性炎症。及早发现在家进行虚拟/技术依赖工作的有害影响可以帮助治疗和预防这些疾病。我们描述了这种现象,并提出了一种治疗方法。
    BACKGROUND: We report on cases of isolated fourth extensor compartment tenosynovitis without evidence of systemic inflammation that occurred in the context of alteration in the work environment due to the COVID-19 epidemic. Early identification of the deleterious effects of virtual/technologically-dependent work from home can aid in treatment and prevention of these conditions. We describe the phenomenon and suggest a treatment approach.
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  • 文章类型: Case Reports
    DeQuervain的腱鞘炎的特征是肌肉肿胀(长肌外展肌(APL)和短肌伸肌(EPB)),它们位于拇指的底部。这是一个非常刺激和痛苦的状况。在许多情况下,晚期检测会导致炎症增加,由于长期的无知和忽视,患者遭受疼痛和不适,影响并限制了他们的日常工作。该疾病是由过度扭曲动作引起的预先存在的肌腱变性引发的。炎性关节炎主要与该病症有关。如果炎症和肿胀持续,肌腱鞘会变厚并收缩。接受高扭矩手腕转动或其他重复日常运动的患者,比如握手,患腱鞘炎的风险更高。这种疾病也可以在没有任何可见的先前创伤或损伤的情况下发生。诊断通常需要进行临床评估;然而,影像学检查可用于确认诊断或检查其他疾病。非甾体抗炎药(NSAIDs),物理治疗,用夹板固定,休息是治疗选择之一。在受影响的区域涂冰和使用夹板是减轻疼痛的几种方法。在对预防性治疗没有反应的情况下,可以考虑进行皮质类固醇注射或手术;因此,建议患者进行小手术,以缓解长期疼痛。
    De Quervain\'s tenosynovitis is characterized by swelling of muscles (abductor pollicis longus (APL) and extensor pollicis (EPB) brevis), and they are located at the base of the thumb. This is a very irritating and painful condition. In many cases, late detection causes an increase in inflammation, and due to prolonged ignorance and neglect, the patient suffers from pain and discomfort that affects and restricts their daily routine work. The disorder tenosynovitis is triggered by preexisting tendon degeneration induced by excessive twisting actions. Inflammatory arthritis is primarily associated with the disorder. The tendon sheath thickens and becomes constricted if the inflammation and swelling persist. Patients who undergo high-torque wrist turning or other repetitive everyday movements, such as handshaking, have a higher risk of developing tenosynovitis. This disease can also occur without any sort of visible prior trauma or injury. Clinical evaluation is usually required for diagnosis; however, imaging studies might be used to confirm the diagnosis or check out alternate diseases. Nonsteroidal anti-inflammatory medication (NSAIDs), physical therapy, immobilization with splints, and rest are among the treatment options. Applying ice to the affected area and applying a splint are a few ways to ease the pain. Corticosteroid injections or surgery may be considered in situations that do not respond to preventive treatment; thus, patients are advised to go for minor surgery to get relief from prolonged pain.
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  • 文章类型: Journal Article
    滑膜囊肿是滑膜组织通过关节囊突出,常被误认为是神经节囊肿.主要区别是滑膜囊肿有滑膜细胞衬里,而神经节囊肿由致密的纤维结缔组织描绘。通常在关节附近发现,滑膜囊肿与骨关节炎等疾病有关,流行于20至50岁的女性。我们提出了一种罕见的病例,在右手的趾浅肌伸肌滑膜囊肿。
    一名53岁的西班牙裔女性因右手背部3年的疼痛史来我们的手部诊所就诊。在探索中,发现一个3×3厘米的软性肿瘤。手术显示指浅伸肌腱内有明显的黄色肿块。手术后,经病理证实为滑膜囊肿,患者出院,无并发症。
    该病例突出了一种罕见的肌腱内滑膜囊肿,并强调了全面了解滑膜囊肿在手肿瘤鉴别诊断中的重要性。
    UNASSIGNED: A synovial cyst is a herniation of synovial tissue through a joint capsule, often mistaken for a ganglion cyst. The key distinctions are that synovial cysts have a synovial cell lining, while a ganglion cyst is delineated by dense fibrous connective tissue. Typically found near joints, synovial cysts are associated with conditions like osteoarthritis, prevalent in females aged 20 to 50. We present a rare case of a synovial cyst in the extensor digitorum superficialis of the right hand.
    UNASSIGNED: A 53-year-old Hispanic female visited our hand clinic due to a 3-year history of pain on the back of her right hand. At exploration, a 3 × 3 cm soft tumor was identified. Surgery revealed a clear-yellowish mass within the extensor digitorum superficialis tendon. Following the surgery, synovial cyst was confirmed by pathology and the patient was discharged without complications.
    UNASSIGNED: This case highlights the rare presentation of an intratendinous synovial cyst and emphasizes the importance of a comprehensive understanding of synovial cysts in the differential diagnosis of hand tumors.
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  • 文章类型: Case Reports
    文献中已经描述了橡皮筋收缩综合征,虽然病例报告很少。以前没有描述过在影像学上显示圆形橡皮筋的腕关节复发性腱鞘炎和滑膜炎。影像学研究显示,伸肌肌腱深处保留了圆形带,嵌入关节囊内。通过开放切口手术去除带导致患者预后的显着改善。证据水平V
    Rubber band constriction syndrome has been described in the literature, although there are very few case reports. Non-healing recurrent tenosynovitis and synovitis of the wrist joint demonstrating a circular rubber band on imaging has not been described before. Imaging studies showed retained circular band deep to the extensor tendons, embedded within the joint capsule. Surgical removal of the band by open incision led to a dramatic improvement in the outcome of the patient. Level of evidence V.
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  • 文章类型: Case Reports
    方法:一名65岁的女性患者,表现为右手腕弥漫性疼痛和肿胀,右手感觉异常,大鱼间消瘦。她的磁共振成像扫描提示腕部屈肌腱鞘炎,正中神经受多个水稻体压迫。她接受了切除活检和正中神经减压术。通过聚合酶链反应(GeneXpert)检测结核分枝杆菌,组织病理学发现干酪样肉芽肿。患者术后开始接受抗结核化疗。
    结论:在印度等地方病国家,结核性屈肌腱鞘炎必须始终是腕关节肿胀的鉴别诊断。
    METHODS: A 65-year-old female patient presented with complaints of diffuse pain and swelling in her right wrist with paresthesia in her right hand with thenar wasting. Her magnetic resonance imaging scan was suggestive of flexor tenosynovitis of the wrist with compression of the median nerve with multiple rice bodies. She underwent excisional biopsy along with median nerve decompression. Mycobacterium tuberculosis was detected by polymerase chain reaction (GeneXpert), and histopathology identified caseous granulomas. The patient was started on antitubercular chemotherapy postoperatively.
    CONCLUSIONS: In endemic countries such as India, tuberculous flexor tenosynovitis must always be a differential diagnosis in cases of wrist swelling with rice bodies.
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  • 文章类型: Case Reports
    非结核分枝杆菌(NTM)是皮肤和肌肉骨骼感染的罕见原因。这里,我们介绍了一名免疫功能低下的患者,左手持续肿胀,手腕,和前臂远端.MRI结果显示屈肌腱鞘炎伴左手和手腕滑膜肥大,并在左手腕的掌侧沿远端屈肌定位含有水稻体的液体。患者接受了屈肌肌腱滑膜切除术,切除的腱鞘膜和肿块的组织学检查显示非干酪性肉芽肿。在微生物培养物中鉴定了胞内分枝杆菌。术后给予抗分枝杆菌治疗以控制感染。本报告强调了在评估慢性手部肿胀时,保持高度怀疑NTM感染的重要性。特别是在免疫系统受损的个体中。
    Nontuberculous mycobacteria (NTM) are uncommon causes of cutaneous and musculoskeletal infections. Here, we present an immunocompromised patient with persistent swelling in the left hand, wrist, and distal forearm. MRI findings revealed flexor tenosynovitis with synovial hypertrophy of the left hand and wrist and loculated fluid containing rice bodies along the distal flexor digitorum muscles in the volar aspect of the left wrist. The patient underwent flexor tenosynovectomy, and histological examination of the excised tenosynovium and mass revealed noncaseating granulomas. Mycobacterium intracellulare was identified in microbiological cultures. Antimycobacterial therapy was administered postoperatively to manage the infection. This report underscores the significance of maintaining a high index of suspicion for NTM infection when assessing chronic hand swelling, particularly in individuals with compromised immune systems.
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  • 文章类型: Journal Article
    越来越多的证据表明肠道微生物群生态失调与滑膜炎和腱鞘炎有关。尽管如此,这些关联是否是因果关系目前尚不清楚.
    进行了双样本孟德尔随机化(MR)研究,以揭示肠道微生物群与滑膜炎和腱鞘炎的因果关系。
    来自大规模全基因组关联研究(GWAS)的汇总统计数据被用作双样本MR分析的基础。因果效应是使用逆方差加权(IVW)估计的,加权中位数,简单模式,MR-Egger,和加权模式方法,其中IVW是重要的方法。同时,使用MR-Egger回归检测和测量多效性和异质性,Cochran的Q统计数据,漏斗图,和MR多效性残差和离群值(MR-PRESSO)方法。
    IVW技术证明了遗传预测五个属,即Gordonibacter[优势比(OR)=0.999,95%置信区间(CI):(0.9977,0.9998),p=0.019],Paraprevotella[OR=0.999,95%CI:(0.9971,0.9999),p=0.036],衣原体[OR=0.998,95%CI:(0.9954,0.9999),p=0.041],RuminoccaceaUCG003[OR=0.997,95%CI:(0.9955,0.9994),p=0.011],和FamilyXIIIAD3011组[OR=0.997,95%CI:(0.9954,0.9992),p=0.006]与滑膜炎和腱鞘炎的风险呈负相关,而另外两个属,即Ruminococstoquesgroup[OR=1.003,95%CI:(1.0004,1.0049),p=0.019]和副杆菌属[OR=1.003,95%CI:(1.0002,1.0052),p=0.035]与滑膜炎和腱鞘炎风险呈正相关。此外,敏感性分析的数据表明没有异常值,水平多效性,或上述肠道菌群对滑膜炎和腱鞘炎因果关系的异质性(p>0.05)。
    研究结果表明,肠道微生物群与滑膜炎和腱鞘炎有因果关系,并确定了影响滑膜炎和腱鞘炎的特定细菌类群,这为肠道微生物群介导的滑膜炎和腱鞘炎的发病机制提供了新的见解。
    UNASSIGNED: Increasing evidence indicates that gut microbiota dysbiosis is related to synovitis and tenosynovitis. Nonetheless, whether these associations are causal is currently unknown.
    UNASSIGNED: A two-sample Mendelian randomization (MR) study was performed to reveal the causality of gut microbiota with synovitis and tenosynovitis.
    UNASSIGNED: The summary statistical data from a large-scale genome-wide association study (GWAS) were applied as the basis for a two-sample MR analysis. The causal effect was estimated using inverse variance weighted (IVW), weighted median, simple mode, MR-Egger, and weighted mode methods, of which IVW was the important method. Meanwhile, the pleiotropy and heterogeneity were detected and measured using MR-Egger regression, Cochran\'s Q statistics, funnel plots, and MR pleiotropy residual sum and outlier (MR-PRESSO) methods.
    UNASSIGNED: The IVW technique demonstrated that genetically predicted five genera, namely Gordonibacter [odds ratio (OR) = 0.999, 95% confidence interval (CI): (0.9977, 0.9998), p = 0.019], Paraprevotella [OR = 0.999, 95% CI: (0.9971, 0.9999), p = 0.036], Lachnoclostridium [OR = 0.998, 95% CI: (0.9954, 0.9999), p = 0.041], RuminococcaceaeUCG003 [OR = 0.997, 95% CI: (0.9955, 0.9994), p = 0.011], and FamilyXIIIAD3011group [OR = 0.997, 95% CI: (0.9954, 0.9992), p = 0.006] were negatively correlated with the risk of synovitis and tenosynovitis, while two other genera, namely Ruminococcustorquesgroup [OR = 1.003, 95% CI: (1.0004, 1.0049), p = 0.019] and Parabacteroides [OR = 1.003, 95% CI: (1.0002, 1.0052), p = 0.035] were positively associated with synovitis and tenosynovitis risk. In addition, the data of sensitivity analyses demonstrated that there were no outliers, horizontal pleiotropy, or heterogeneity in the causal relationship of the above-mentioned gut microbiota on synovitis and tenosynovitis (p > 0.05).
    UNASSIGNED: The results of the study suggested that the gut microbiota was causally involved in synovitis and tenosynovitis and identified specific bacterial taxa that affect synovitis and tenosynovitis, which provide new insights into the pathogenesis underlying the development of synovitis and tenosynovitis mediated by gut microbiota.
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    文章类型: Journal Article
    背景:化脓性屈肌腱鞘炎(PFT)是一种常见且严重的手部感染。早期出现的患者可以用静脉注射抗生素治疗。
    目的:确定由动物咬伤引起的PFT和抗生素治疗是否由于广泛的软组织损伤和不同的细菌菌群而导致与其他疾病病因不同的结果。
    方法:我们在2013年至2020年期间对43例PFT患者进行了回顾性队列研究。将动物咬伤后出现PFT的10例患者与由任何其他病因引起的出现PFT的患者进行比较。
    结果:被咬伤的患者就医时间较早:1.9±1.4天,而5.3±4.7天(P=0.001)。尽管演示速度更快,研究组患者接受了与对照组相似的抗生素类型和持续时间.所有患者最初在手外科医生的监视下接受静脉抗生素治疗。研究组的一名患者(10%)和四名对照(12%)接受了手术治疗(P=1)。平均随访时间为17±16天。在后续行动结束时,研究组1例(10%)患者和对照组3例(9%)患者存在轻度活动限制,对照组1例(3%)患者存在中度活动限制(P=0.855).
    结论:静脉抗生素治疗,结合手外科医生的密集随访,是治疗由动物叮咬引起的PFT的可行选择。
    BACKGROUND: Pyogenic flexor tenosynovitis (PFT) is a common and severe hand infection. Patients who present early can be treated with intravenous antibiotics.
    OBJECTIVE: To determine whether PFT caused by animal bites and treated with antibiotics leads to a different outcome than other disease etiologies due to the extensive soft tissue insult and different bacterial flora.
    METHODS: We conducted a retrospective cohort study of 43 consecutive patients who presented with PFT between 2013 and 2020. The 10 patients who presented with PFT following an animal bite were compared to those who presented with PFT caused by any other etiology.
    RESULTS: Patients who were bitten pursued medical attention sooner: 1.9 ± 1.4 days compared with 5.3 ± 4.7 days (P = 0.001). Despite the quicker presentation, patients from the study group received similar antibiotic types and duration as controls. All patients were initially treated with intravenous antibiotics under surveillance of a hand surgeon. One patient (10%) from the study group and four controls (12%) were treated surgically (P = 1). Average follow-up was 17 ± 16 days. At the end of follow-up, one (10%) patient from the study group and three (9%) controls sustained mild range of motion limitation and one (3%) patient from the control group had moderate limitations (P = 0.855).
    CONCLUSIONS: Intravenous antibiotic treatment, combined with an intensive hand surgeon follow-up, is a viable option for the treatment of PFT caused by animal bites.
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  • 文章类型: Journal Article
    皮肤和软组织是最常见的感染部位。感染可能涉及表皮到深层肌肉和骨骼。大多数感染通过邻接结构传播,尽管在免疫受损状态和非典型感染的情况下可能发生血行扩散。虽然感染的临床诊断是可能的,它往往缺乏特异性,需要使用成像进行确认。美国的横断面成像,CT,磁共振成像不仅经常用于诊断,而是描述感染的程度并帮助管理。尽管如此,成像特征有相当大的重叠,因此,将影像学特征与临床特征结合起来管理软组织感染至关重要.放射科医师必须了解不同感染的影像特征及其模拟,以及每种成像技术在适当的临床情况下正确使用它们的利弊。在这次审查中,我们总结了主要软组织感染的最新循证特征.
    Skin and soft tissues are among the most common sites of infections. Infections can involve the superficial epidermis to deep muscles and bones. Most infections spread through contiguous structures, although hematogenous spread can occur in the setting of an immunocompromised state and with atypical infections. While clinical diagnosis of infections is possible, it often lacks specificity, necessitating the use of imaging for confirmation. Cross-sectional imaging with US, CT, and MRI is frequently performed not just for diagnosis, but to delineate the extent of infection and to aid in management. Nonetheless, the imaging features have considerable overlap, and as such, it is essential to integrate imaging features with clinical features for managing soft tissue infections. Radiologists must be aware of the imaging features of different infections and their mimics, as well as the pros and cons of each imaging technique to properly use them for appropriate clinical situations. In this review, we summarize the most recent evidence-based features of key soft tissue infections.
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