子宫内膜癌(EC)磁共振成像(MRI)的T2图,良性子宫内膜病变(BELs),正常子宫内膜(NE)很少有报道。本研究旨在确定EC的MRIT2值,BELs,和NE来研究T2值是否可以区分它们,并评估EC的侵袭性。
总共,73名患者[EC,51岁(年龄,57.4±5.4年);BELs,22岁(年龄,57.8±11.8岁]和23名正常志愿者(年龄,包括56.1±6.6年)。EC(I型和II型)的MRIT2值,BEL,和NE组进行描述和比较。分析ECMRIT2值与病理特征[国际妇产科联合会(FIGO)分期和分级]的关系。
NE的中值T2值,BEL,EC为197.5(142.9-324.0)ms,131.1(103.2-247.9)ms,103.0(71.6-243.5)ms(P<0.001),分别。I型和II型EC的T2中值分别为100.8(71.62-130.44)ms和125.7(119.7-243.5)ms,分别。NE之间的T2值存在显着差异,BEL,I型EC,和II型EC组(P<0.001),除了II型EC和BEL组之间(P=0.938)。I型EC的MRIT2值明显低于II型EC(P=0.001)。具有不同FIGO分期(P=0.273)或肿瘤分级(P=0.686)的I型EC患者没有显着差异。
MRI的T2作图有可能定量区分EC,BELs,和NE以及I型和II型EC之间。
The T2 mapping of magnetic resonance imaging (MRI) in endometrial cancer (EC), benign endometrial lesions (BELs), and normal endometrium (NE) has rarely been reported. This study aimed to determine the T2 values of MRI in EC, BELs, and NE to investigate whether the T2 values can differentiate them and to assess the aggressiveness of EC.
In total, 73 patients [EC, 51 (age, 57.4 ± 5.4 years); BELs, 22 (age, 57.8 ± 11.8 years)] and 23 normal volunteers (age, 56.1 ± 6.6 years) were included. The T2 values of MRI of the EC (type I and II), BEL, and NE groups were described and compared. The relationships between the T2 values of MRI in EC and the pathological characteristics [International Federation of Gynecology and Obstetrics (FIGO) stage and grade] were analyzed.
The median T2 values of NE, BEL, and EC were 197.5 (142.9-324.0) ms, 131.1 (103.2-247.9) ms, and 103.0 (71.6-243.5) ms (P < 0.001), respectively. The median T2 values of type I and type II EC were 100.8 (71.62-130.44) ms and 125.7 (119.7-243.5) ms, respectively. There were significant differences in the T2 values among the NE, BEL, type I EC, and type II EC groups (P < 0.001) except for between the type II EC and BEL groups (P = 0.938). The T2 value of MRI in type I EC was significantly lower than that in type II EC (P = 0.001). There were no significant differences in patients with type I EC having different FIGO stages (P = 0.273) or tumor grades (P = 0.686).
T2 mapping of MRI has the potential to quantitatively differentiate between EC, BELs, and NE as well as between type I and type II EC.