Abstract：
OBJECTIVE: T2 magnetic resonance imaging (MRI) mapping has been applied to carpal tunnel syndrome (CTS) for quantitative assessment of the median nerve. However, quantitative changes in the median nerve before and after surgery using T2 MRI mapping remain unclear. We aimed to investigate whether pathological changes could be identified by pre- and postoperative T2 MRI mapping of the median nerve in CTS patients after open carpal tunnel release.
METHODS: This was a prospective study that measured median nerve T2 and cross-sectional area (CSA) values at the distal carpal tunnel, hamate bone, proximal carpal tunnel, and forearm levels pre- and postoperatively. Associations between T2, CSA, and nerve conduction latency were also evaluated.
RESULTS: A total of 36 patients with CTS (mean age, 64.5 ± 11.7 years) who underwent surgery were studied. The mean preoperative T2 values significantly decreased from 56.3 to 46.9 ms at the proximal carpal tunnel levels (p = .001), and from 52.4 to 48.7 ms at the hamate levels postoperatively (p = .04). Although there was a moderate association between preoperative T2 values at the distal carpal tunnel levels and distal motor latency values (r = -.46), other T2 values at all four carpal tunnel levels were not significantly associated with CSA or nerve conduction latency pre- or postoperatively.
CONCLUSIONS: T2 MRI mapping of the carpal tunnel suggested a decrease in nerve edema after surgery. T2 MRI mapping provides quantitative information on the median nerve before and after surgery.
METHODS: This was a prospective study that measured median nerve T2 and cross-sectional area (CSA) values at the distal carpal tunnel, hamate bone, proximal carpal tunnel, and forearm levels pre- and postoperatively. Associations between T2, CSA, and nerve conduction latency were also evaluated.
RESULTS: A total of 36 patients with CTS (mean age, 64.5 ± 11.7 years) who underwent surgery were studied. The mean preoperative T2 values significantly decreased from 56.3 to 46.9 ms at the proximal carpal tunnel levels (p = .001), and from 52.4 to 48.7 ms at the hamate levels postoperatively (p = .04). Although there was a moderate association between preoperative T2 values at the distal carpal tunnel levels and distal motor latency values (r = -.46), other T2 values at all four carpal tunnel levels were not significantly associated with CSA or nerve conduction latency pre- or postoperatively.
CONCLUSIONS: T2 MRI mapping of the carpal tunnel suggested a decrease in nerve edema after surgery. T2 MRI mapping provides quantitative information on the median nerve before and after surgery.
摘要：
目的：T2磁共振成像（MRI）作图已应用于腕管综合征（CTS），以定量评估正中神经。然而,使用T2MRI标测术前后正中神经的定量变化尚不清楚.我们旨在研究开放腕管松解术后CTS患者的正中神经的术前和术后T2MRI定位是否可以确定病理变化。
方法：这是一项前瞻性研究，该研究测量了腕管远端的正中神经T2和横截面积（CSA）值，Hamate骨,近端腕管,和前臂水平术前和术后。T2、CSA、和神经传导潜伏期也进行了评估。
结果：共有36例CTS患者（平均年龄，64.5±11.7年）接受手术的人进行了研究。在近端腕管水平，术前平均T2值从56.3ms显著降低至46.9ms（p=.001），从52.4到48.7ms，在术后的Hamate水平（p=.04）。尽管腕管远端水平的术前T2值与远端运动潜伏期值之间存在中度关联（r=-0.46），所有四个腕管水平的其他T2值与CSA或神经传导潜伏期术前或术后均无显著相关.
结论：腕管的T2MRI图显示手术后神经水肿减少。T2MRI作图提供手术前后正中神经的定量信息。
方法：这是一项前瞻性研究，该研究测量了腕管远端的正中神经T2和横截面积（CSA）值，Hamate骨,近端腕管,和前臂水平术前和术后。T2、CSA、和神经传导潜伏期也进行了评估。
结果：共有36例CTS患者（平均年龄，64.5±11.7年）接受手术的人进行了研究。在近端腕管水平，术前平均T2值从56.3ms显著降低至46.9ms（p=.001），从52.4到48.7ms，在术后的Hamate水平（p=.04）。尽管腕管远端水平的术前T2值与远端运动潜伏期值之间存在中度关联（r=-0.46），所有四个腕管水平的其他T2值与CSA或神经传导潜伏期术前或术后均无显著相关.
结论：腕管的T2MRI图显示手术后神经水肿减少。T2MRI作图提供手术前后正中神经的定量信息。
