目的:本研究旨在确定基于电话的支持计划(PBSP)对新诊断的乳腺癌女性的有效性。
方法:设计两组重复测量的随机对照试验。参与者包括94名年龄在18-60岁的患者,他们在中国一家三级医院新诊断为乳腺癌并接受化疗。他们被随机分配到干预组和对照组。干预组的参与者参加了四个阶段的PBSP,由四个互动部分组成:学习,讨论,问专家,和个人故事,加上常规护理。结果包括患者自我护理自我效能感,心理困扰(包括症状困扰,焦虑,和抑郁),和生活质量。这些在三个时间点进行了评估:干预前(T1),干预后(T2),使用自我护理自我效能感量表进行随访(T3),M.D.Anderson症状清单,医院焦虑抑郁量表,和全球健康状况量表。
结果:完成干预后,干预组的参与者有显著(p<.001)更高的自我护理自我效能(T2:Mdiff=11.49,T3:Mdiff=22.33),更好的生活质量(T2:Mdiff=8.18,T3:Mdiff=17.19),较低的症状困扰(T2:Mdiff=-26.68,T3:Mdiff=-54.76),减少焦虑(T2:Mdiff=-2.52,T3:Mdiff=-5.11),与对照组相比,抑郁程度较低(T2:Mdiff=-3.61,T3:Mdiff=-6.71)。
结论:这些研究结果表明PBSP是有效的。医疗保健专业人员,尤其是护士,可以利用它来提高自我护理自我效能和生活质量,以及减少新诊断乳腺癌女性的心理困扰。
背景:泰国临床试验登记处#TCTR20230321010。
OBJECTIVE: This study aimed to determine the effectiveness of a Phone-Based Support Program (PBSP) for newly diagnosed women with breast cancer.
METHODS: A two-group repeated measures randomized controlled trial was designed. Participants included 94 patients aged 18-60 years who were newly diagnosed with breast cancer and undergoing chemotherapy in a tertiary hospital in China. They were randomly assigned to the intervention and the control groups. Participants in the intervention group were enrolled in a four-session PBSP, consisting of four interactive sections: learning, discussion, ask-the-expert, and personal stories, plus the routine care. Outcomes included patients\' self-care self-efficacy, psychological distress (including symptom distress, anxiety, and depression), and quality of life. These were assessed at three time points: pre-intervention (T1), post-intervention (T2), and follow-up (T3) by using the self-care self-efficacy scale, the M.D. Anderson Symptom Inventory, the hospital anxiety and depression scale, and the global health status scale.
RESULTS: After completion of the intervention, participants in the intervention group had significantly (p < .001) higher self-care self-efficacy (T2: Mdiff = 11.49, T3: Mdiff = 22.33), better quality of life (T2: Mdiff = 8.18, T3: Mdiff = 17.19), lower symptom distress (T2: Mdiff = -26.68, T3: Mdiff = -54.76), less anxiety (T2: Mdiff = -2.52, T3: Mdiff = -5.11), and less depression (T2: Mdiff = -3.61, T3: Mdiff = -6.71) than those in the control group.
CONCLUSIONS: These findings indicate that the PBSP is effective. Healthcare professionals, especially nurses, could utilize it to enhance self-care self-efficacy and quality of life, as well as decrease psychological distress among women newly diagnosed breast cancer.
BACKGROUND: The Thai Clinical Trial Registry #TCTR20230321010.