METHODS: This multicenter, longitudinal cohort study includes 48 heart recipients (HTRs), 12 women, and 36 men, with a median age of 57 years followed from pretransplant to 5 years post-transplant. Symptom distress was explored by means of four instruments measuring psychological general wellbeing, transplant specific wellbeing, pain, and fatigue.
RESULTS: Transplant specific well-being for the whole improved in a stepwise manner during the first 5 years compared to pretransplant. Heart transplant recipients with poor psychological wellbeing were significantly more burdened by symptom distress, in particular sleep problems and fatigue, for up to 5 years after HTx, and their transplant-specific well-being never improved compared to baseline. The prevalence of pain varied from 40% to 60% and explained a significant proportion of the variance in transplant-specific well-being, while psychological general well-being was mainly predicted by overall symptom distress.
CONCLUSIONS: The presence of distressing symptoms explains a significant proportion of poor psychological wellbeing both among HTRs reporting chronic pain and those without pain.
方法:这个多中心,纵向队列研究包括48名心脏接受者(HTRs),12个女人,36人,从移植前到移植后5年,平均年龄为57岁。通过四种测量心理总体幸福感的仪器来探索症状困扰,移植特定的健康,疼痛,和疲劳。
结果:与移植前相比,在最初的5年中,整体的移植特异性幸福感逐步改善。心理健康差的心脏移植受者因症状困扰而承受的负担明显更大,特别是睡眠问题和疲劳,HTX之后长达5年,与基线相比,他们的移植特异性健康状况从未改善。疼痛的患病率从40%到60%不等,并解释了移植特异性幸福感差异的显着比例,而心理总体幸福感主要由总体症状困扰预测。
结论:令人痛苦的症状的存在解释了在报告慢性疼痛的HTRs和没有疼痛的HTRs中心理健康差的显著比例。