Surgical Technique

外科技术
  • 文章类型: Journal Article
    目的:描述一种新技术,胸椎后路前位和融合(PTAF),对于一种特殊类型的胸椎后纵韧带骨化(T-OPLL),并评估其安全性和有效性。
    方法:从2020年7月至12月,连续5例位于胸椎椎体(VB)水平的喙型T-OPLL患者接受了PTAF手术。他们的人口统计数据,放射学参数,围手术期并发症,记录并分析手术相关结果.使用改良的日本骨科协会(mJOA)量表评估手术结果,回收率(RR)采用平林法计算。
    结果:所有患者均随访至少2年。OPLL的平均厚度为9.4±1.0mm,OPLL椎管占用率为67.7%±8.5%。术后,OPLL的平均前位移距离为8.1±1.8mm,脊柱的平均缩短距离为6.0±1.13mm。平均手术时间和出血量分别为158.2±26.3min和460±89.4mL,分别。围手术期并发症为脑脊液漏和器械失效,各2例。平均mJOA评分从手术前的3.6±2.9增加到末次随访时的9.4±3.0。平均RR为84.2±30.5%。
    结论:初步临床结果表明,PTAF是治疗喙型T-OPLL的一种安全有效的方法,其顶点位于VB水平,并具有较高的椎管占用率。
    OBJECTIVE: To describe a novel technique, posterior thoracic antedisplacement and fusion (PTAF), for a special type of ossification of the posterior longitudinal ligament in the thoracic spine (T-OPLL), and to evaluate its safety and efficacy.
    METHODS: From July to December 2020, five consecutive patients with beak-type T-OPLL located at the thoracic vertebral body (VB) level underwent PTAF surgery. Their demographic data, radiological parameters, perioperative complications, and surgery-related findings were recorded and analyzed. The surgical outcomes were assessed using a modified Japanese Orthopedic Association (mJOA) scale, and the recovery rate (RR) was calculated using the Hirabayashi\'s method.
    RESULTS: All patients were followed up for at least two years. The mean thickness of OPLL was 9.4 ± 1.0 mm, and the OPLL spinal canal occupying ratio was 67.7% ± 8.5%. Postoperatively, the mean antedisplacement distance of OPLL was 8.1 ± 1.8 mm, and the average shortened distance of the spinal column was 6.0 ± 1.13 mm. The mean operation time and blood loss were 158.2 ± 26.3 min and 460 ± 89.4 mL, respectively. Perioperative complications were cerebrospinal fluid leakage and instrument failure, 2 cases each. The mean mJOA score was increased from 3.6 ± 2.9 before surgery to 9.4 ± 3.0 at the last follow-up, and the average RR was 84.2 ± 30.5%.
    CONCLUSIONS: The preliminary clinical outcomes indicate that PTAF is a safe and effective method for the treatment of beak-type T-OPLL, which has its apex located at the VB level and has a high spinal canal occupation ratio.
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  • 文章类型: Journal Article
    背景:脾曲近端Hirschsprung病(HSCR)或需要重做牵拉(PT)的儿童有PT紧张和缺血的风险,这可能导致泄漏,狭窄,或神经节化的肠丢失。结肠旋转是一种用于最小化张力和避免十二指肠阻塞的技术。这项研究的目的是描述这种技术和一系列需要这种干预的患者的结果。
    方法:所有患者均接受初始改道和结肠标测。去旋转过程涉及剩余结肠的动员,通过造口闭合部位逆时针旋转,通过(右结肠)放置在骨盆右侧,结扎结肠中动脉,保留从回结肠动脉延伸的边缘分支。这种操作可以防止肠系膜血管对十二指肠的压迫,并允许等位肌,无张力吻合.在许多情况下,术中吲哚菁绿荧光血管造影术(ICG-FA)被用来绘制牵拉结肠的血液供应图。我们回顾了2014年至2023年所有接受结肠移位的HSCR儿童的结局。进行描述性统计。
    结果:包括37名儿童。大多数为男性(67.5%),原始过渡区靠近直肠乙状结肠(81.1%)。PT时的中位年龄为9.3个月[6.1-39.7]。中位手术时间为6.6h[4.9-7.4],19例(51.4%)使用ICG-FA。大多数儿童没有术后30天并发症(67.6%);在那些出现并发症的儿童中,电解质失衡的再入院最为常见(50.0%).PT吻合术中吻合口漏0例。在长期随访中,中位数4.4年[2.3-7.0],三名儿童(8.1%)出现吻合口狭窄,所有人都适合肛门扩张,和5次经历小肠结肠炎发作(14.7%)。大多数儿童每天大便1至4次(58.8%)。
    结论:结肠旋转是确保结肠长度良好灌注的有用策略,保护边缘动脉供血,避免十二指肠压迫,并确保无张力吻合,并发症最少。
    方法:原始研究,回顾性队列。
    方法:III.
    BACKGROUND: Children with Hirschsprung disease (HSCR) proximal to the splenic flexure or those needing a redo pull-through (PT) are at risk for tension and ischemia of the PT which could result in leak, stricture, or loss of ganglionated bowel. Colonic derotation is a technique used to minimize tension and avoid duodenal obstruction. The aim of this study was to describe this technique and outcomes in a series of patients requiring this intervention.
    METHODS: All patients underwent initial diversion and colonic mapping. The derotation procedure involves mobilization of the remaining colon, counterclockwise rotation via the stoma closure site, placement of the pull through (the right colon) lying on the right of the pelvis, and ligation of the middle colic artery with preservation of the marginal branch running from the ileocolic artery. This maneuver prevents compression of the duodenum by the mesenteric vessels and allows for an isoperistaltic, tension-free anastomosis. Intraoperative indocyanine green fluorescence angiography (ICG-FA) was utilized in many of the cases to map the blood supply of the pull-through colon. We reviewed outcomes for all children with HSCR who underwent colonic derotation from 2014 to 2023. Descriptive statistics were performed.
    RESULTS: There were 37 children included. Most were male (67.5%) with the original transition zone proximal to the rectosigmoid (81.1%). The median age at PT was 9.3 months [6.1-39.7]. Median operative time was 6.6 h [4.9-7.4] and 19 cases (51.4%) used ICG-FA. Most children had no 30-day postoperative complications (67.6%); in those who did develop complications, readmissions for electrolyte imbalance was most common (50.0%). There were zero cases of anastomotic leak at PT anastomosis. At long-term follow up, median 4.4 years [2.3-7.0], three children (8.1%) developed an anastomotic stricture, all were amenable to anal dilation, and five experienced episodes of enterocolitis (14.7%). Most children had between 1 and 4 stools per day (58.8%).
    CONCLUSIONS: Colonic derotation is a useful strategy to ensure well-perfused colonic length, protect the marginal artery blood supply, avoid duodenal compression, and ensure a tension-free anastomosis with minimal complications.
    METHODS: Original research, retrospective cohort.
    METHODS: III.
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  • 文章类型: Case Reports
    脉络丛乳头状瘤(CPP)是一种罕见的良性颅内肿瘤,主要表现在儿童的侧脑室。占所有原发性颅内肿瘤的0.3%-0.6%。通过对侧后半球间横裂肌入路(PITTA)在侧脑室三角区的CPP极为罕见。在这里,我们报告了这个罕见的病例。一个7岁的女孩出现头痛。脑部磁共振成像显示心房周围病变,组织病理学检查证实CPP(WHOI级)。对侧PITTA是安全的,有效,合理,适用于侧脑室三角区的某些病变。与常规方法相比,它提供了更宽的手术角度(特别是对于横向延伸)并且降低了光学辐射的干扰风险。使用多种现代神经外科技术,包括介入栓塞,术中导航,显微镜,和电生理监测,使程序更容易,更准确,神经内窥镜增加了显微镜的可视化,可以减少手术并发症。
    Choroid plexus papilloma (CPP) is a rare benign intracranial tumor origin that predominantly manifests in the lateral ventricle in children, accounting for 0.3%-0.6% of all primary intracranial tumors. It is extremely rare to have the CPP in the trigone of the lateral ventricle through the contralateral posterior interhemispheric transfalcine transprecuneus approach (PITTA). Herein, we report this rare case. A 7-year-old girl presented with headache. Magnetic resonance imaging of the brain showed periatrial lesions, and histopathological examination confirmed CPP (WHO grade I). The contralateral PITTA is a safe, effective, reasonable, and appropriate for some lesions in the trigone of the lateral ventricle. It provides a wider surgical angle (especially for the lateral extension) and reduces the risk of disturbance of the optic radiation compared with the conventional approaches. The use of multiple modern neurosurgical techniques, including interventional embolization, intraoperative navigation, microscope, and electrophysiological monitoring, make the procedure much easier and more accurate, and the neuroendoscope adds to the visualization of the microscope and can reduce surgical complications.
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  • 文章类型: Case Reports
    背景:描述非压缩性髓内螺纹钉(IMTN)固定远端尺骨颈骨折的手术技术,并介绍使用这种新技术治疗的四名患者的临床和影像学结果。
    方法:在一个1级创伤中心,我们对2022~2024年间逆行IMTN治疗的尺颈远端骨折患者进行了回顾性研究.排除标准包括随访不足。一名外科医生通过三角形纤维软骨复合体(TFCC)的中央盘使用经皮逆行IMTN固定进行所有手术。患者在手术后两周开始了一系列运动(ROM)方案。术后X线图像用于计算IMTN直径与骨折部位近端尺骨峡部直径的比率。位移的射线照相变化,成角,在第一次和最后一次随访的射线照片之间计算尺骨方差。收集包括握力和ROM在内的功能结果。
    结果:在2022年至2024年之间,4例尺骨颈远端骨折患者接受了逆行IMTN治疗。术后随访至少三个月。均为女性,平均年龄65岁。所有尺骨远端骨折均与手术治疗的桡骨远端关节内骨折相关。所有患者均接受75mm长度和4.5mm直径IMTNs治疗。在所有情况下,IMTN与峡部的比率均大于60%。在最后的随访中,平均射线照相位移和角度没有变化。尺骨平均方差增加1.2mm。在最后的后续行动中,无术后并发症.没有病例显示尺侧腕关节疼痛,骨不连,或需要翻修手术。
    结论:逆行IMTN内固定术是治疗远端尺骨颈骨折的一种新的手术技术。我们发现,我们的患者在没有报告尺侧腕关节疼痛的情况下,术后影像学和功能结果有限,但有希望。骨不连,或需要拆卸硬件。
    BACKGROUND:  To describe the surgical technique of non-compressive intramedullary threaded nail (IMTN) fixation of distal ulnar neck fractures and present the clinical and radiographic outcomes of four patients treated with this novel technique.
    METHODS: At a single Level 1 Trauma Center, a retrospective review was conducted for patients with distal ulnar neck fractures treated with retrograde IMTN between 2022 and 2024. Exclusion criteria included inadequate follow-up. A single surgeon performed all procedures using percutaneous retrograde IMTN fixation through the central disc of the triangular fibrocartilage complex (TFCC). Patients initiated a range of motion (ROM) protocol two weeks post-operatively. Post-operative radiographic images were used to calculate the ratio of IMTN diameter to the distal ulnar medullary isthmus diameter proximal to the fracture site. Radiographic changes in displacement, angulation, and ulnar variance were calculated between the first and last follow-up radiographs. Functional outcomes including grip strength and ROM were collected.
    RESULTS: Four patients with distal ulnar neck fractures were treated with retrograde IMTN between 2022 and 2024. They were followed for a minimum of three months post-operatively. All were female with an average age of 65 years. All distal ulna fractures were associated with operatively treated intraarticular distal radius fractures. All patients were treated with 75 mm length and 4.5 mm diameter IMTNs. IMTN-to-Isthmus ratio was greater than 60% in all cases. Average radiographic displacement and angulation were unchanged at the final follow-up. The average ulnar variance increased by 1.2 mm. At the final follow-up, there were no post-operative complications. No cases demonstrated ulnar-sided wrist pain, nonunion, or required revision surgery.
    CONCLUSIONS: Retrograde IMTN fixation is a novel surgical technique for the treatment of distal ulnar neck fractures. We found limited but promising post-operative radiographic and functional outcomes in our patients without reported ulnar-sided wrist pain, nonunion, or need for hardware removal.
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  • 文章类型: Journal Article
    目的:椎弓根螺钉的放置指导在脊柱融合中至关重要,和脊柱手术机器人旨在提高准确性和减少并发症。当前的文献尚未比较可用的机器人系统的相对优点。在这次审查中,作者旨在1)评估脊柱机器人文献的当前状态;2)基于准确性对机器人性能进行荟萃分析,速度,和安全性;3)为机器人系统选择提供建议。
    方法:遵循PRISMA指南,作者对PubMed进行了系统的文献综述,Embase,科克伦图书馆,WebofScience,和Scopus截至2022年4月28日,用于研究批准的用于放置腰椎椎弓根螺钉的机器人。三位评审员筛选并提取了与研究特征有关的数据,准确率,术中修正,和再操作。次要性能指标包括手术时间,失血,和辐射暴露。作者使用随机效应模型对机器人的性能进行了统计比较,以说明研究内部和之间的差异。每个机器人还与传统技术的性能基准进行了比较,包括徒手,荧光镜,和CT导航插入。最后,我们进行了Duval和Tweedie修剪和填充检验,以评估是否存在发表偏倚.
    结果:作者确定了46项研究,描述了4670名患者和25,054个螺钉,评估了4种不同的机器人系统:MazorX,罗莎,ExcelsiusGPS,和Cirq.Gertzbein-Robbins分类A级或B级螺钉的加权准确率如下:ExcelsiusGPS,98.0%;ROSA,98.0%;Mazor,98.2%;和Cirq,94.2%。没有机器人比其他机器人更准确。然而,ExcelsiusGPS的精度明显高于传统方法,Mazor和ROSA的准确度明显高于透视。术中翻修率为Cirq,0.55%;ROSA,0.91%;马祖,0.98%;和ExcelsiusGPS,1.08%。再次手术率为Cirq,0.28%;ExcelsiusGPS,0.32%;和Mazor,0.76%(ROSA未报告再次手术)。所有机器人的手术时间都相似。ExcelsiusGPS和Mazor的失血量均明显少于ROSA。Cirq的辐射暴露量最低。机器人往往更准确,通常与徒手相比,它们的使用与更少的再次手术和更少的失血有关。荧光镜,或CT导航技术。
    结论:基于关键指标,机器人平台的性能相当,准确率高,术中翻修率和再手术率低。脊柱机器人的出版速度将继续加快,选择机器人将取决于实践的背景。
    OBJECTIVE: Pedicle screw placement guidance is critical in spinal fusions, and spinal surgery robots aim to improve accuracy and reduce complications. Current literature has yet to compare the relative merits of available robotic systems. In this review, the authors aimed to 1) assess the current state of spinal robotics literature; 2) conduct a meta-analysis of robotic performance based on accuracy, speed, and safety; and 3) offer recommendations for robotic system selection.
    METHODS: Following PRISMA guidelines, the authors conducted a systematic literature review across PubMed, Embase, Cochrane Library, Web of Science, and Scopus as of April 28, 2022, for studies on approved robots for placing lumbar pedicle screws. Three reviewers screened and extracted data relating to the study characteristics, accuracy rate, intraoperative revisions, and reoperations. Secondary performance metrics included operative time, blood loss, and radiation exposure. The authors statistically compared the performance of the robots using a random-effects model to account for variation within and between the studies. Each robot was also compared with performance benchmarks of traditional techniques including freehand, fluoroscopic, and CT-navigated insertion. Finally, we performed a Duval and Tweedie trim-and-fill test to assess for the presence of publication bias.
    RESULTS: The authors identified 46 studies, describing 4670 patients and 25,054 screws, that evaluated 4 different robotic systems: Mazor X, ROSA, ExcelsiusGPS, and Cirq. The weighted accuracy rates of Gertzbein-Robbins classification grade A or B screws were as follows: ExcelsiusGPS, 98.0%; ROSA, 98.0%; Mazor, 98.2%; and Cirq, 94.2%. No robot was significantly more accurate than the others. However, the accuracy of the ExcelsiusGPS was significantly higher than that of traditional methods, and the accuracies of the Mazor and ROSA were significantly higher than that of fluoroscopy. The intraoperative revision rates were Cirq, 0.55%; ROSA, 0.91%; Mazor, 0.98%; and ExcelsiusGPS, 1.08%. The reoperation rates were Cirq, 0.28%; ExcelsiusGPS, 0.32%; and Mazor, 0.76% (no reoperations were reported for ROSA). Operative times were similar for all robots. Both the ExcelsiusGPS and Mazor were associated with significantly less blood loss than the ROSA. The Cirq had the lowest radiation exposure. Robots tended to be more accurate and generally their use was associated with fewer reoperations and less blood loss than freehand, fluoroscopic, or CT-navigated techniques.
    CONCLUSIONS: Robotic platforms perform comparably based on key metrics, with high accuracy rates and low intraoperative revision and reoperation rates. The spinal robotics publication rate will continue to accelerate, and choosing a robot will depend on the context of the practice.
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  • 文章类型: Journal Article
    目的:立体定向技术在神经外科中起着重要作用。开发具有高效工作流程和精确手术执行的小型化颅骨机器人是这些技术更广泛应用的重要一步。在这里,作者描述了他们使用美敦力隐形Autoguide小型化颅骨机器人的经验。
    方法:对2020年至2022年的75例病例进行回顾性分析。分析了使用StealthAutoguide机器人进行手术的患者的手术适应症和准确性,手术时间,和临床结果。结果定义如下:对于立体脑电图(SEEG),确定癫痫发作焦点且不需要任何修正或额外引线的电极放置模式;对于活检,获得诊断组织的病例百分比;对于激光间质热疗法(LITT),激光光纤放置足以消融的病例百分比。手术并发症定义为无症状或有症状的脑出血。新的神经缺陷,或需要电极,激光光纤,或活检针重新定位或翻修。
    结果:在75个标签上案例中使用了隐形自动引导机器人,包括40例SEEG癫痫病灶定位病例,19LITT案件,立体定向活检16例。活检入口处的平均真实目标误差(RTE)为1.48±0.84mm,1.36±0.89mm,适用于Visualase激光光纤放置,SEEG为1.24±0.72mm。活检针放置时,目标处的平均RTE为1.56±0.95mm,1.42±0.93mm,适用于Visualase激光光纤放置,SEEG电极放置1.31±0.87mm。单侧SEEG病例的手术时间平均为52分钟(平均6.5分钟/导联,平均8个电极)。双侧SEEG病例平均耗时105分钟(平均7.5分钟/铅,平均14个电极)。在SEEG人口中,没有修订或不成功的癫痫发作定位。活检,在100%的病例中获得了诊断组织。对于LITT,在100%的病例中,纤维放置足以进行消融.没有出现有症状或无症状的脑出血,并且不需要重新定位或更换激光光纤的情况,电极,或者活检针.一名患者在激光消融后出现短暂性颅神经III麻痹,并在10周内消退。机器人平台与作为站的隐形自动指南之间的通信失败需要取消1个程序。
    结论:MedtronicStealthAutoguide机器人系统在活检中用途广泛,SEEG,和激光消融适应症。设置和手术执行是高效的,具有高度的准确性和一致性。
    OBJECTIVE: Stereotactic techniques play an important role in neurosurgery. The development of a miniaturized cranial robot with an efficient workflow and accurate surgical execution is an important step in a broader application of these techniques. Herein, the authors describe their experience with the Medtronic Stealth Autoguide miniaturized cranial robot.
    METHODS: A retrospective review of 75 cases from 2020 to 2022 was performed. The patients who had undergone surgery utilizing the Stealth Autoguide robot were analyzed for surgical indication and accuracy, operative time, and clinical outcome. The outcomes were defined as follows: for stereoelectroencephalography (SEEG), the electrode placement pattern that identified the seizure focus and did not require any revision or additional leads; for biopsy, the percentage of cases in which diagnostic tissue was obtained; and for laser interstitial thermal therapy (LITT), the percentage of cases in which laser fiber placement was adequate for ablation. Surgical complications were defined as any asymptomatic or symptomatic intracerebral hemorrhage, new neurological deficit, or need for electrode, laser fiber, or biopsy needle repositioning or revision.
    RESULTS: The Stealth Autoguide robot was utilized in 75 on-label cases, including 40 SEEG cases for seizure focus localization, 19 LITT cases, and 16 stereotactic biopsy cases. The mean real target error (RTE) at the entry was 1.48 ± 0.84 mm for biopsy, 1.36 ± 0.89 mm for Visualase laser fiber placement, and 1.24 ± 0.72 mm for SEEG. The mean RTE at the target was 1.56 ± 0.95 mm for biopsy needle placement, 1.42 ± 0.93 mm for Visualase laser fiber placement, and 1.31 ± 0.87 mm for SEEG electrode placement. The surgical time for unilateral SEEG cases took an average 52 minutes (average 6.5 mins/lead, average 8 electrodes). Bilateral SEEG cases took an average 105 minutes (average 7.5 mins/lead, average 14 electrodes). In the SEEG population, there were no revised or unsuccessful seizure localizations. For biopsy, diagnostic tissue was obtained in 100% of cases. For LITT, fiber placement was adequate for ablation in 100% of cases. There were no cases of symptomatic or asymptomatic intracerebral hemorrhage, and no cases required repositioning or replacement of the laser fiber, electrode, or biopsy needle. One patient experienced transient cranial nerve III palsy following laser ablation that resolved in 10 weeks. A failure of communication between the robotic platform and the Stealth Autoguide as a station required the cancellation of 1 procedure.
    CONCLUSIONS: The Medtronic Stealth Autoguide robot system is versatile across biopsy, SEEG, and laser ablation indications. Setup and surgical execution are efficient with a high degree of accuracy and consistency.
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  • 文章类型: Journal Article
    目的:在鼻内镜手术(EES)中已采用各种非血管化或血管化技术来修复肿瘤切除术后的术中脑脊液(CSF)渗漏。血管化鼻中隔皮瓣(VNSF),游离鼻中隔移植物(FNSG),游离鼻甲移植物(FTG),经常使用阔筋膜和捣碎肌(FLMM)。需要澄清在不同区域缺陷中应用这些移植物的结果。
    方法:回顾性分析2012年1月至2021年1月接受EES手术的162例颅底肿瘤患者的数据。这些区域包括前颅底(ASB),塞拉地区,clivus和颞下窝(ITF)。维修故障率(RFR),评估脑膜炎发生率和相关危险因素。
    结果:总计,162例患者在颅底的四个部位进行了172例重建。术后有7例(4.3%)脑脊液漏,需要第二次修理。ASB的RFR,塞拉地区,Clivus,ITF为2.6%,2.2%,16.7%,0%,分别。clivus缺损是修复失败的独立危险因素(P<0.01)。术后脑膜炎发生率为5.6%。修复失败是脑膜炎的独立危险因素(P<0.01)。
    结论:VNSF,FNSG,FTG,FLMM是可靠的自体材料,可用于修复EES期间不同区域的硬脑膜缺损。Clivus重建仍然是一个巨大的挑战,具有较高的RFR和脑膜炎发生率。修复失败与术后脑膜炎显著相关。
    OBJECTIVE: Various non-vascularized or vascularized techniques have been adopted in endoscopic endonasal surgery (EES) for repairing intraoperative cerebrospinal fluid (CSF) leaks after tumor resection. Vascularized nasoseptal flaps (VNSF), free nasoseptal grafts (FNSG), free turbinate grafts (FTG), fascia lata and mashed muscle (FLMM) are frequently used. Outcomes of those grafts applied in the defects of different regions need to be clarified.
    METHODS: The data from a series of 162 patients with skull base tumor who underwent EES that had intraoperative CSF leak between Jan 2012 and Jan 2021 were retrospectively analyzed. The regions included anterior skull base (ASB), sellar region, clivus and infratemporal fossa (ITF). Repair failure rate (RFR), meningitis rate and associated risk factors were assessed.
    RESULTS: In total, 172 reconstructions were performed in 162 patients for the four sites of the skull base. There were 7 cases (4.3%) that had postoperative CSF leaks, which required second repair. The RFR for ASB, sellar region, clivus, and ITF was 2.6%, 2.2%, 16.7%, and 0%, respectively. The clivus defect was an independent risk factor for repair failure (P<0.01). The postoperative meningitis rate was 5.6%. Repair failure was an independent risk factor for meningitis (P < 0.01).
    CONCLUSIONS: VNSF, FNSG, FTG, FLMM are reliable autologous materials for repairing the dural defects in different regions during EES. Clivus reconstruction remains a great challenge, which had a higher RFR and meningitis rate. Repair failure is significantly associated with postoperative meningitis.
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  • 文章类型: Journal Article
    背景:原发性硬化性胆管炎(PSC)肝移植(LT)期间的胆道重建技术仍存在争议。这项研究旨在评估进行导管到导管(DD)吻合术或Roux-en-Y肝空肠吻合术(HJ)的PSC患者胆道并发症的发生率。
    方法:6月1日之间在单中心接受LT的PSC患者的回顾性医疗记录回顾,2000年12月31日,2022年执行。主要和次要终点是胆道狭窄(吻合口[BAS]和非吻合口狭窄[NAS])和非狭窄并发症的发生率。分别。进行单变量和多变量回归分析以确定与BAS形成的关联。使用Kaplan-Meier曲线评估患者生存。
    结果:从101例患者的105例移植中,54例(51.4%)和51例(48.5%)接受了DD和HJ吻合术。平均接受者年龄和随访时间为47±13岁和98±69个月。BAS更为常见(48.1%与27.5%,OR2.45,95%CI1.09-5.54,p=0.03),发生时间更早(4.8个月,IQR2.3-13.1vs.41.8个月,IQR7.2-88.7,p=0.001)在DD比HJ组。NAS(在36.2%的移植中可见)在HJ(38.9%)和DD(33.3%)组中的发生率相当(p=0.53)。在到达NAS的时间方面,队列之间没有发现差异,延长胆道扩张计划的要求(临床上有意义的胆道狭窄),胆漏,和移植失败。在多变量分析中,只有吻合技术与BAS相关(DD校正OR3.00,95%CI1.19-7.56,p=0.02)。
    结论:在精心挑选的PSC患者中,肝移植后,DD吻合与HJ吻合产生相似的结果。
    BACKGROUND: Biliary reconstruction technique during liver transplant (LT) for primary sclerosing cholangitis (PSC) remains controversial. This study aimed to evaluate the incidence of biliary complications in patients with PSC having a duct-to-duct (DD) anastomosis or Roux-en-Y hepaticojejunostomy (HJ).
    METHODS: A retrospective medical record review of patients with PSC undergoing LT at a single center between June 1st, 2000 and December 31st, 2022 was performed. Primary and secondary endpoints were the incidence of biliary strictures (anastomotic [BAS] and non-anastomotic strictures [NAS]) and non-stricture complications, respectively. Univariable and multivariable regression analyses were performed to identify associations with BAS formation. Patient survival was assessed using a Kaplan-Meier curve.
    RESULTS: From 105 transplants performed for 101 patients, 54 (51.4%) and 51 (48.5%) received DD and HJ anastomoses. Mean recipient age and follow-up was 47 ± 13 years and 98 ± 69 months. BAS was more common (48.1% vs. 27.5%, OR 2.45, 95% CI 1.09-5.54, p = 0.03) and occurred earlier (4.8 months, IQR 2.3-13.1 vs. 41.8 months, IQR 7.2-88.7, p = 0.001) in the DD than the HJ group. NAS (seen in 36.2% of transplants) had a comparable incidence (p = 0.53) in HJ (38.9%) and DD (33.3%) groups. No difference was seen between cohorts regarding time to NAS, requirement for extended biliary dilatation programs (clinically significant biliary stricture), bile leak, and graft failure. On multivariable analysis, only the anastomotic technique was associated with BAS (DD adjusted OR 3.00, 95% CI 1.19-7.56, p = 0.02).
    CONCLUSIONS: In carefully selected patients with PSC, DD anastomosis yielded similar outcomes to HJ anastomosis after liver transplantation.
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  • 文章类型: Journal Article
    半球癫痫在儿童中非常常见,与成年人相比,包括各种病理底物,如半脑畸形,拉斯穆森脑炎,斯特奇-韦伯综合征,和头颅,在其他人中。这些患者最常成为药物抗性的,因此需要手术治疗。虽然解剖性大脑半球切除术是有可能的,全世界大多数癫痫手术中心青睐的技术是功能性半球切开术,结果相同,术后并发症较少。因此,小儿癫痫神经外科医生必须熟悉这些技术。本视频详细描述了腹膜半球切开术的所有手术方面。
    Hemispheric epilepsy is quite frequent in children, compared with adults, and encompasses pathological substrates as diverse as hemimegalencephaly, Rasmussen encephalitis, Sturge-Weber syndrome, and porencephaly, among others. These patients most often become pharmacoresistant and thus require surgical management. Although anatomical hemispherectomy is a possibility, the technique that is favored by most epilepsy surgery centers worldwide is functional hemispherotomy, which results in equivalent outcomes with fewer postoperative complications. Therefore, it is essential that pediatric epilepsy neurosurgeons become familiar with these techniques. The present video describes in detail all surgical aspects of the perisylvian hemispherotomy.
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  • 文章类型: Case Reports
    深部脑刺激(DBS)已成为几种运动障碍的重要治疗选择;然而,急性并发症的管理,如急性硬膜下血肿(ASDH),仍然具有挑战性。这是一名患有帕金森病的71岁女性患者,在双侧DBS放置12年后出现ASDH。意识改变后入院,影像学显示,由于血肿,DBS电极发生明显位移。在保留DBS系统的情况下,进行了内窥镜疏散的紧急开颅手术。术后,证实血肿完全疏散,患者经历了显著的临床改善。ASDH在接受DBS的患者中引起显著的电极移位。血肿清除后,观察到电极返回到适当的位置,患者对刺激表现出良好的临床反应。为了保护DBS电极,通过小的开颅手术进行内镜血肿清除术可能是有用的.
    Deep brain stimulation (DBS) has emerged as an important therapeutic option for several movement disorders; however, the management of acute complications, such as acute subdural hematoma (ASDH), remains challenging. This is the case of a 71-year-old woman with Parkinson\'s disease who developed ASDH 12 years after bilateral DBS placement. On admission with altered consciousness, imaging revealed significant displacement of the DBS electrodes because of the hematoma. Emergent craniotomy with endoscopic evacuation was performed with preservation of the DBS system. Postoperatively, complete evacuation of the hematoma was confirmed, and the patient experienced significant clinical improvement. ASDH causes significant electrode displacement in patients undergoing DBS. After hematoma evacuation, the electrodes were observed to return to their proper position, and the patient exhibited a favorable clinical response to stimulation. To preserve the DBS electrodes, endoscopic hematoma evacuation via a small craniotomy may be useful.
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