■大量研究表明,SARS-CoV-2的收缩可能导致记忆障碍,即使在复苏后的几个月里。在这方面,研究表明,COVID-19主要靶向颞叶内的结构和皮质,和海马,记忆和空间导航的关键大脑结构。这项研究的目的是调查COVID-19大流行对主观记忆不适的潜在影响,这代表了在没有客观记忆障碍的情况下,个体对记忆微妙变化的感知。
■探讨COVID-19大流行如何影响主观记忆不适,我们纳入了主观记忆投诉的临时自我报告措施,“主观记忆投诉问卷”(SMCQ)和“前瞻性和回顾性记忆问卷”(PRMQ),在我们的横断面研究中。两项措施都涉及两个时期:大流行前时期(T0)和调查管理时刻(T1)(12月28日,2021年2月6日,2022年)。
■207名意大利参与者参加了调查,其中189名参与者被纳入最终样本。大多数参与者是女性,他们的年龄从55岁到65岁不等。研究显示,与T0相比,T1时的总PRMQ得分显著增加(p=0.02)。然而,COVID-19阴性个体和自完成调查之日起最近12个月内COVID-19检测呈阳性的个体的PRMQ和SMCQ评分无显著差异.McNemar的测试显示,SMCQ的第1项(“您认为自己有记忆问题吗?”(p=0.016)和第10项(“您比以前更经常丢失物体”)(0.019)的得分在统计学上显着增加,而对于PRMQ来说,在几个单独的项目中发现了显著的增加。
■我们的研究表明,在大流行期间,主观记忆投诉增加,可能是由于压力和社会隔离的复合效应,而不仅仅是由于COVID-19感染。尽管检测到COVID-19与报告的前瞻性记忆问题之间存在边际关联,需要进一步调查以了解其持续影响.
UNASSIGNED: A significant body of research has suggested that the contraction of SARS-CoV-2 may cause memory impairment, even in the months following recovery. In this regard, studies suggest that COVID-19 predominantly targets structures and cortices within the temporal lobe, and the hippocampus, a critical brain structure for memory and spatial navigation.The purpose of this study was to investigate the potential impact of the COVID-19 pandemic on subjective memory complaints, which represent an individual\'s perception of subtle changes in memory in the absence of an objective memory impairment.
UNASSIGNED: to explore how the COVID-19 pandemic may affect subjective memory complaints, we incorporated ad hoc self-reported measures of subjective memory complaints, the \"Subjective Memory Complaints Questionnaire\" (SMCQ) and the \"Prospective and Retrospective Memory Questionnaire\" (PRMQ), in our cross-sectional study. Both measures referred to two periods: the pre-pandemic period (T0) and the moment of survey administration (T1) (December 28th, 2021, to February 6th, 2022).
UNASSIGNED: 207 Italian participants accessed the survey, out of which 189 participants were included in the final sample. The majority of the participants were females, and their age ranged from 55 to 65 years. The study revealed a significant increase in the total PRMQ score at T1 compared to T0 (p = 0.02). However, no significant differences were found between PRMQ and SMCQ scores of COVID-19-negative individuals and those who tested positive for COVID-19 in the last 12 months from the date of completing the survey. McNemar\'s test showed a statistically significant increase in the score of item 1 (\"Do you think that you have a memory problem?\" (p = 0.016) and item 10 (\"Do you lose objects more often than you did previously\") (0.019) of the SMCQ, while for the PRMQ, significant increases were found in several individual items.
UNASSIGNED: our study suggests that subjective memory complaints increased during the pandemic, potentially due to the compound effects of stress and social isolation, rather than solely due to COVID-19 infection. Although a marginal association between COVID-19 and reported prospective memory issues was detected, further investigation is warranted to understand its persistent effects.