目的:本研究旨在确定摩洛哥卡萨布兰卡地区发生葡萄球菌尿路感染(UTI)的患病率和危险因素。
方法:在卡萨布兰卡,摩洛哥,在2020年1月至2022年12月期间,对772例UTIs患者进行了回顾性评估.该研究包括两组患者:患有葡萄球菌UTI的患者和没有葡萄球菌UTI的患者。性,年龄,慢性疾病,抗生素暴露,导尿术,泌尿外科手术,和UTIs病史是评估的风险变量。我们采用逻辑回归模型来确定葡萄球菌UTI的预测特征。
结果:在772个非重复个体中,8种葡萄球菌导致16.84%的UTI。感染腐生链球菌的患者(35.38%)是最常见的,其次是感染表皮葡萄球菌(24.61%),金黄色葡萄球菌(13.85%),和溶血链球菌(10.78%)。多因素logistic回归分析显示男性(95%CI:0.261-0.563),免疫抑制和免疫抑制治疗(95%CI:0.0068-0.64),慢性病(95%CI:0.407-0.965),以前的UTI(95%CI:0.031-0.228),每天排尿次数超过8次(95%CI:1.04-3.29),每天一次或两次排尿频率(95%CI:1.05-2.39),和导尿(95%CI:0.02-0.22)是葡萄球菌UTI的最可能预测因子。此外,较大比例的葡萄球菌UTIs患者了解与葡萄球菌UTIs相关的危险因素(52.31%,χ2=4.82,=0.014)。
结论:这是第一个评估葡萄球菌引起的尿路感染的预测因素的全球研究。监测这些因素将使医疗机构能够制定有效的策略来管理尿路感染和对抗抗生素耐药性。
OBJECTIVE: This study aimed to ascertain the prevalence and risk factors for developing staphylococcal urinary tract infections (UTIs) in the Casablanca area of Morocco.
METHODS: In Casablanca, Morocco, a retrospective evaluation of 772 UTIs patients was conducted between January 2020 and December 2022. The research included two groups of patients: those with staphylococcal UTIs and those without. Sex, age, chronic illnesses, antibiotic exposure, urinary catheterization, urological surgery, and UTIs history were the risk variables assessed. We employed a logistic regression model to identify the characteristics that were predictive of staphylococcal UTIs.
RESULTS: Eight staphylococcal species were responsible for 16.84% of UTIs in 772 non-repeating individuals. Patients infected with S. saprophyticus (35.38%) were the most common, followed by those infected with S. epidermidis (24.61%), S. aureus (13.85%), and S. hemolyticus (10.78%). Multivariate logistic regression analysis revealed that male sex (95% CI: 0.261-0.563), immunosuppression and immunosuppressive treatments (95% CI: 0.0068-0.64), chronic diseases (95% CI: 0.407-0.965), previous UTIs (95% CI: 0.031-0.228), frequency of urination more than 8 times a day (95% CI:1.04-3.29), frequency of urination once or twice a day (95% CI: 1.05-2.39), and urinary catheterization (95% CI: 0.02-0.22) were the most likely predictors of staphylococcal UTIs. In addition, a larger proportion of patients with staphylococcal UTIs were made aware of the risk factors associated with staphylococcal UTIs (52.31%, χ2 = 4.82, = 0.014).
CONCLUSIONS: This is the first global study to evaluate the predictive factors for acquiring UTIs caused by
staphylococci. Monitoring these factors will enable medical authorities to devise effective strategies for managing UTIs and combating antibiotic resistance.