Split thickness skin graft

分裂厚度皮肤移植
  • 文章类型: Case Reports
    我们回顾了一例由于石蜡瘤导致的全阴茎皮肤置换,并进行了厚度分裂的微网状皮肤移植(微网状STSG)。
    We review a case of total penile skin replacement with split-thickness micromesh skin graft (micromesh STSG) due to paraffinoma.
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  • 文章类型: Case Reports
    Fournier坏疽(FG)是一种威胁生命的会阴和外生殖器的坏死性软组织感染,主要发生在肥胖,糖尿病男性。治疗的主要方法是通过早期积极的手术切除进行源头控制。广泛的手术切除可导致显著的软组织缺损,其可被毁容且难以闭合。最常见的闭合方法是裂层皮肤移植(STSG)。最近,除STSG外,还使用了自体皮肤细胞悬液(ASCS)技术,以提供更好的伤口愈合和闭合。这个病人伤口进展良好,followingFG,通过使用STSG的ASCS,尽管与伤口有关的挑战,解剖位置,合并症,尺寸,和病人的病史。
    Fournier gangrene (FG) is a life-threatening necrotizing soft-tissue infection of the perineum and external genitalia, which primarily occurs in obese, diabetic males. The mainstay of treatment is source control via early aggressive surgical excision. Wide surgical excision can result in significant soft tissue defects that can be disfiguring and difficult to close. The most common method of closure is split-thickness skin grafting (STSG). Recently, autologous skin cell suspension (ASCS) technology has been used in addition to STSG to provide better wound healing and closure. This patient experienced excellent wound progression, following FG, through the application of ASCS with STSG, despite challenges related to the wounds, anatomical location, comorbidities, size, and the patient\'s medical history.
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  • 文章类型: Case Reports
    先天性角膜炎(ACC)是一种罕见的先天性疾病,定义为没有皮肤,最常见的是头皮。虽然确切的发病率仍然不确定,ACC由于其可变的表现和相关的并发症而在临床管理中提出了重大挑战。我们介绍了一个新生儿男性的病例,该病例具有归因于ACC的大头皮缺陷,并发了危及生命的头皮出血.尽管管理面临挑战,包括反复感染和失败的皮肤移植,经过一系列手术干预后,患者最终获得了令人满意的愈合,包括局部换位皮瓣手术。这个案例强调了多学科方法管理行政协调会的重要性,针对个体患者特征和相关风险。虽然ACC的离散病变通常具有良好的预后,广泛的缺陷构成了发病率和死亡率的重大风险,强调需要仔细考虑治疗方案,并密切对受影响的个体进行临床监测。
    Aplasia cutis congenita (ACC) is a rare congenital disease defined by the absence of skin, most commonly on the scalp. While the exact incidence remains uncertain, ACC presents a significant challenge in clinical management due to its variable presentation and associated complications. We present the case of a newborn male with a large scalp defect attributed to ACC, complicated by a life-threatening scalp hemorrhage. Despite challenges in management, including recurrent infections and failed skin grafts, the patient ultimately achieved satisfactory healing following a series of surgical interventions, including local transposition flap procedures. This case underscores the importance of a multidisciplinary approach to managing ACC, tailored to individual patient characteristics and associated risks. While discrete lesions of ACC typically have a favorable prognosis, extensive defects pose significant risks of morbidity and mortality, highlighting the need for careful consideration of treatment options and close clinical monitoring of affected individuals.
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  • 文章类型: Case Reports
    使用收缩环继发的阴茎绞窄是一种罕见的泌尿外科急症,需要紧急减压以防止长时间的血管阻塞导致坏死和坏疽。当前的文献主要包括案例介绍,这些案例介绍侧重于通过移除戒指在急性环境中的管理。在这里,我们描述了一名患者的手术治疗,该患者在自我摘除收缩环后以延迟的方式出现。我们讨论了清创和分层厚度皮肤移植的保留肺切除术技术。
    Penile strangulation secondary to utilization of a constrictive ring is a rare urologic emergency that requires urgent decompression to prevent prolonged vascular obstruction resulting in necrosis and gangrene. Current literature is mainly comprised of case presentations that focus on management in the acute setting via removal of the ring. Herein, we describe surgical management of a patient who presents in delayed fashion after self-removal of the constrictive ring. We discuss our penectomy-sparing technique of debridement and split thickness skin graft.
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    文章类型: Journal Article
    Minimally invasive surgery is becoming the standard of care across surgical subspecialties. Several new \"minimally invasive\" options for burn debridement and autografting exist. Enzymatic bromelain-based debridement (BBD) and autologous skin cell spray (ASCS) have independently proven to reduce the rate of split-thickness skin grafting (STSG) and decrease donor site size when grafting is performed. There is a paucity in the literature regarding the combination of these two therapies. The purpose of this study is to characterize a cohort of patients treated with both BBD and ASCS and qualitatively compare data to expected outcomes without these therapies. This retrospective study of a single academic burn center\'s experience using BBD and ASCS together included 13 patients with a total burn surface area (TBSA) from 1-30% and all had >50% deep partial thickness. All patients received BBD and ASCS. Deeper burns additionally received STSG with ASCS overspray. Median burn size was 14% TBSA (IQR:5.45,20), donor site size was 225 sq cm (IQR:28.5,556.5), and ratio of donor site area to total treatment area of 0.082 (IQR: 0.039, 0.241) was observed. Median observed length of stay (LOS) was 19 days (IQR:10,27), expected LOS was 15.4 days, and O/E ratio 1.06. Donor sites in both groups of patients were much smaller than expected versus treatment with conventional meshed STSG alone and length of stay is lower than expected based on burn size. An emphasis on expenses and scar development will guide future studies into the patient subset and wound features that are best for this combination treatment.
    La chirurgie mini-invasive devient le standard de traitement dans de nombreuses spécialités. Il y a de telles possibilités en brûlologie comme de débridement enzymatique à la bromélaïne (DEB) et la pulvérisation de cellules cutanées autologues (PCCA) qui ont chacun permis de diminuer le recours aux autogreffes et de réduire la surface de la zone donneuse. La littérature est pauvre en ce qui concerne la combinaison des 2. Cette étude rétrospective rapporte une cohorte de 13 patients traités dans notre centre par combinaison de DEB et PCCA, et compare le résultat avec celui attendu avec un traitement conventionnel. Les patients étaient brûlés sur 1 à 30% de SCT (médiane 14, IQR 5,45-20) dont au moins la moitié de 2ème profond, ayant tous reçu une combinaison de DEB et PCCA. Les atteintes plus profondes étaient greffées, avec une PCCA par dessus. Le site donneur avait une surface médiane de 225 cm2 (IQR 28,5-556,5) avec un rapport surface donneuse/surface traitée de 0,082 (IQR 0,039-0,241). La durée médiane de séjour est de 19 jours (IQR 10-27) quand elle était supposée être de 15,4 jours (rapport 1,06). Les sites donneurs étaient plus exigus que sous traitement conventionnel et la durée de séjour plus courte que supposée. Une étude plus précise sur les séquelles et les coûts permettrait de cibler plus précisément les patients susceptibles de bénéficier de ce protocole.
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  • 文章类型: Journal Article
    背景:下肢远端重建具有挑战性。本研究旨在提出一种治疗创伤性软组织缺损的方案。关键概念是将重建外科医生的外科器械与高压氧疗法提供的优势相结合。方法:这项回顾性研究分析了2010年至2021年间57例单侧或双侧膝关节远端下肢创伤患者的资料,涉及软组织,没有立即重建的迹象。在重建程序之前,所有患者都接受了棒拭子手术,以收集微生物样本和清创。将患者分为两个治疗组,只有一组接受高压氧治疗的联合治疗程序。负压伤口治疗(NPWT)仅在根据缺损深度和伤口渗出物认为必要时使用。外科技术,结果,并对并发症进行了讨论。结果:所有患者均完全康复,无主要并发症,仅观察到轻微并发症。与对照组观察到的相同并发症相比,接受HBOT治疗的研究组的并发症发生率较低,最小和部分移植物丢失的百分比较低。无患者出现HBOT相关并发症。发现完成愈合的时间和从重建到愈合的时间显著减少(分别为p=0.002和p<0.00001)。结论:HBOT治疗组的并发症发生率较低。在软组织重建之前施用HBOT显着减少了完成愈合的时间以及从皮肤移植到愈合的时间间隔。然而,应设计前瞻性研究和更大队列的随机试验,以研究HBOT治疗伴广泛软组织缺损的下肢损伤的疗效.
    Background: Distal lower extremity reconstruction is challenging. This study aims to propose a protocol for the treatment of traumatic soft tissue defects. The key concept is to combine the surgical armamentarium of the reconstructive surgeon with the advantages provided by hyperbaric oxygen therapy. Methods: This retrospective study analyzed data of 57 patients affected with unilateral or bilateral lower extremity trauma distal to the knee and involving soft tissues with no indication of immediate reconstruction between 2010 and 2021. Before the reconstructive procedure, all the patients underwent a stick swab procedure for the collection of microbiological samples and debridement. Patients were divided into two treatment groups and only one group underwent a combined therapeutic procedure with hyperbaric oxygen therapy. Negative pressure wound therapy (NPWT) was employed only if deemed necessary according to the defect\'s depth and wound exudate. Surgical techniques, outcomes, and complications were discussed. Results: All patients achieved a complete recovery with no major complications and only minor complications observed. The study group treated with HBOT had a lower complication rate and lower percentages of minimal and partial graft loss compared with the same complications observed in the control group. No patients experienced HBOT-related complications. Significant reductions in the time to complete healing and the time from reconstruction to healing were found (p = 0.002 and p < 0.00001, respectively). Conclusions: A lower complication rate was observed in the group treated with HBOT. The administration of HBOT prior to soft tissue reconstruction significantly reduced the time to complete healing and the time interval from skin grafting to healing. However, prospective studies and randomized trials with larger cohorts should be designed to investigate the efficacy of HBOT for the treatment of lower extremity injuries with extensive soft tissue defects.
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  • 文章类型: Case Reports
    裂层植皮(STSG)是具有挑战性的手术伤口的前线治疗,包括糖尿病足溃疡,腿部静脉性溃疡,和术后缺陷。这项研究探讨了在Mohs显微外科手术(MMS)后,采用捏合移植技术将STSG用于难以治愈的手术伤口。一名83岁的患者左小腿MMS后缺损无改善,使用捏合移植技术从右大腿内侧接受了STSG。移植物用网状敷料固定,胶带,和压缩包扎。患者在五周内经历了完全的上皮再形成和疼痛减轻。强调STSG对挑战性病例的疗效。这个案例强调了考虑STSG的重要性,尤其是在具有挑战性的地方,作为一种快速有效的治疗方法,提高了生活质量。捏合移植技术是MMS之后的有用选择。这项研究鼓励Mohs外科医生考虑在具有挑战性的位置进行STSG重建,尤其是小腿.
    Split-thickness skin grafting (STSG) is a frontline treatment for challenging surgical wounds, including diabetic foot ulcers, venous leg ulcers, and post-surgical defects. This study explores the use of STSG employing the pinch graft technique for hard-to-heal surgical wounds following Mohs micrographic surgery (MMS). An 83-year-old patient with a non-improving post-MMS defect on the left lower leg underwent STSG from the right inner thigh using the pinch graft technique. The grafts were secured with a mesh dressing, adhesive strips, and compression bandaging. The patient experienced complete re-epithelialization and reduced pain within five weeks, emphasizing the efficacy of STSG for challenging cases. This case underscores the importance of considering STSG, especially in challenging locations, as a rapid and efficient treatment with improved quality of life. The pinch graft technique is presented as a useful option following MMS. This study encourages Mohs surgeons to consider STSG for reconstruction in challenging locations, especially on the lower leg.
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  • 文章类型: Case Reports
    医疗保健提供者评估患有神经系统疾病的患者,内脏,或与预期严重程度不成比例的皮肤症状可能需要在差异中考虑卟啉症。卟啉病是一种遗传性疾病,其中血红素途径的有毒代谢物增加。卟啉病携带者无症状,不会出现经典症状,水平也不会升高,直到疾病由某些药物引起,荷尔蒙,或特发性原因,如创伤的压力。急性间歇性卟啉症,一种急性卟啉症,是一种罕见的常染色体显性疾病,导致功能失调的胆色素原脱氨酶。因此,这增加了神经毒性胆色素原,并随后增加了δ-氨基乙酰丙酸。这两种代谢物都会引起神经内脏症状,在急性发作时困扰患者。我们介绍了一例罕见的急性间歇性卟啉症病例,表现为烧伤患者。患者出现急性间歇性卟啉症的症状,包括精神状态改变和腹痛伴有长期酗酒和吸烟史。负面工作,包括影像学和与急性间歇性卟啉病一致的相关表现的发现导致了卟啉升高的发现。患者的病程和由于受伤而死亡,可以深入了解烧伤患者的急性间歇性卟啉病的表现。
    Healthcare providers evaluating patients presenting with neurological, visceral, or cutaneous symptoms that are disproportionate to the expected severity may need to consider porphyria in the differential. Porphyria is an inherited condition in which toxic metabolites of the heme pathway are increased. Carriers of porphyrias are asymptomatic and will not present with classical symptoms, nor will levels be elevated, until the disease is induced by certain drugs, hormones, or idiopathic causes such as the stress of trauma. Acute intermittent porphyria (AIP), a form of acute porphyria, is a rare autosomal dominant disease that results in a dysfunctional porphobilinogen deaminase. This consequently increases neurotoxic porphobilinogen and subsequent increase in δ-aminolevulinic acid. Both of these metabolites cause neurovisceral symptoms that afflict the patient in acute attacks. We present a rare case of AIP manifested in a burn patient suffering a burn injury. The patient presented with symptoms indicative of AIP, including altered mental status and abdominal pain accompanied with a chronic history of alcoholism and smoking. A negative work-up, including imaging and findings of associated manifestations consistent with AIP led to a discovery of elevated porphyrins. The patient\'s course and death due to his injuries gives insight into the presentation of AIP in a burn patient.
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  • 文章类型: Journal Article
    化脓性汗腺炎(HS)是一种慢性皮肤病,显着降低患者的生活质量,尤其是影响亲密区域。手术治疗是治疗HS可用的工具之一,这可以显著改善患者的生活质量。
    为了评估在Sie-mianowice的烧伤治疗中心接受手术治疗的31名患者的手术治疗,随访6个月。
    31例HS患者采用经典重建方法进行手术。患者在门诊随访6个月。收集31例术后患者的临床资料并进行统计学分析。
    83.87%的患者完全愈合。研究表明,仅在6个月的随访后,1例(3.23%)患者发生了手术部位的HS复发。我们发现患者年龄和体重指数(BMI)之间存在统计学上显著的正相关(p<0.050)。疾病持续时间和诊断时间。BMI值还与疾病持续时间和诊断时间相关,而疾病持续时间与诊断时间相关。
    手术治疗是HS的有效方法。术后6个月复发率相对较低,在大多数患者中,完全愈合,支持手术治疗的良好治疗效果。
    UNASSIGNED: Hidradenitis suppurativa (HS) is a chronic skin disease that significantly reduces the quality of life of patients, especially affecting the intimate areas. Surgical treatment is one of the tools available for treating HS, which can significantly improve patients\' quality of life.
    UNASSIGNED: To evaluate the surgical treatment of 31 patients treated surgically at the Centre for Burns Treatment in Sie-mianowice Śląskie, with a follow-up of 6 months.
    UNASSIGNED: Thirty-one HS patients were operated on with classical reconstructive methods. The patients were followed up for 6 months in the outpatient clinic. We gathered clinical data of 31 post-operative patients and statistical analysis was performed.
    UNASSIGNED: 83.87% of the patients were completely healed. The study showed that HS recurrence in the surgical site occurred in 1 (3.23%) patient only after 6 months of follow-up. We found a statistically significant (p < 0.050) positive correlation between patients\' age and body mass index (BMI), disease duration and time of diagnosis. BMI value additionally correlated with disease duration and time of diagnosis, while disease duration correlated with time of diagnosis.
    UNASSIGNED: Surgical treatment is an effective method in HS. The relatively low recurrence rate after 6 months and, in most patients, full healing, support the good therapeutic effect of surgical treatment.
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  • 文章类型: Journal Article
    背景:虽然恶性阴茎疾病的积极非器官保留手术治疗有趋势,目前存在多种保留阴茎的选择,但迄今为止,该领域的功能结局和患者报告结局(PRO)的报道并不理想.
    目的:本研究的目的是报告连续一系列患有扁平苔藓硬化(LS)或局部阴茎癌(PC)的患者的全龟头表面置换(TGR)的功能结果和PRO。
    方法:从2004年到2018年,一系列连续的患者在三级转诊网络中接受了TGR以管理LS或局部PC。回顾性分析患者的临床记录和手术记录。用Stata12进行统计分析。
    结果:使用国际勃起功能指数(IIEF)和国际前列腺症状评分(IPSS)验证问卷记录了泌尿和性结局,而从5项“特设”电话问卷中推断PROs在手术后1年进行。
    结果:共纳入37例连续患者。组织学结果显示16例患者的LS,其余21人被诊断为PC。患者出现的最常见原因是局部疼痛(32.4%)。瘙痒(37.8%)和出血(29.7%)。中位随访时间为22(IQR13-77)个月。中位年龄为62岁(IQR55-68)。评估泌尿和性功能的问卷均未显示手术后有任何明显恶化。89.2%的病例完全维持Glans敏感性。94.5%的患者报告对阴茎的美学外观完全满意,并在必要时会考虑再次进行相同的手术。91.9%的患者会向其他人推荐相同的程序。86.4%的患者报告生活质量总体改善。
    结论:对于某些良性或恶性阴茎病变病例,TGR应被视为首选治疗方法。
    我们的研究有一些局限性,首先是它的回顾性。此外,尽管是迄今为止最大的系列之一,随访时间有限,缺乏对照组.
    结论:TGR是一种极好的手术选择,可确保令人满意的排尿和性功能,以及选定阴茎病变病例的美容。
    BACKGROUND: Whilst there is a trend away from aggressive nonorgan sparing surgical treatments for malignant penile disease, a variety of penile preservation options exist but functional outcomes and patient reported outcomes (PROs) in this area are poorly reported to date.
    OBJECTIVE: The aim of this study is to report functional outcomes and PROs of total glans resurfacing (TGR) in a consecutive series of patients with lichen sclerosis (LS) or localized penile cancer (PC).
    METHODS: From 2004 to 2018 a consecutive series of patients underwent TGR for the management of LS or localized PC in a tertiary referral network. Patient clinical records and operative notes were retrospectively reviewed. Statistical analysis was conducted with Stata 12.
    RESULTS: Urinary and sexual outcomes were recorded utilizing both the International Index of Erectile Function (IIEF) and International Prostate Symptom Score (IPSS) validated questionnaires while PROs were extrapolated from a 5-item \"ad hoc\" telephone questionnaire administered at 1 year post procedure.
    RESULTS: 37 consecutive patients were enrolled. Histology results demonstrated LS in 16 patients, with the remaining 21 having a diagnosis of PC. The most common reasons for patient presentation were local pain (32.4%), pruritus (37.8%) and bleeding (29.7%). Median follow-up was 22 (IQR 13-77) months. Median age was 62 (IQR 55-68).Neither of the questionnaires assessing urinary and sexual function showed any significant deterioration after surgery. Glans sensitivity was fully maintained in 89.2% of cases. 94.5% of patients reported to be fully satisfied with the aesthetic appearance of the penis and would consider undergoing the same procedure again if necessary. 91.9% of patients would recommend the same procedure to someone else. An overall improvement of the quality of life was reported by 86.4% of patients.
    CONCLUSIONS: TGR should be considered a treatment of choice for selected cases of benign or malignant penile lesions.
    UNASSIGNED: Our study has some limitations, the first being its retrospective nature. Furthermore, despite being one of the largest series to date, follow-up duration is somewhat limited and a control group is lacking.
    CONCLUSIONS: TGR represents an excellent surgical option ensuring satisfactory voiding and sexual function, as well as cosmesis for selected cases of penile lesions.
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