关键词: autologous skin cell suspension fournier gangrene marsupialization necrotizing soft tissue infection (nsti) split thickness skin graft

来  源:   DOI:10.7759/cureus.62639   PDF(Pubmed)

Abstract:
Fournier gangrene (FG) is a life-threatening necrotizing soft-tissue infection of the perineum and external genitalia, which primarily occurs in obese, diabetic males. The mainstay of treatment is source control via early aggressive surgical excision. Wide surgical excision can result in significant soft tissue defects that can be disfiguring and difficult to close. The most common method of closure is split-thickness skin grafting (STSG). Recently, autologous skin cell suspension (ASCS) technology has been used in addition to STSG to provide better wound healing and closure. This patient experienced excellent wound progression, following FG, through the application of ASCS with STSG, despite challenges related to the wounds, anatomical location, comorbidities, size, and the patient\'s medical history.
摘要:
Fournier坏疽(FG)是一种威胁生命的会阴和外生殖器的坏死性软组织感染,主要发生在肥胖,糖尿病男性。治疗的主要方法是通过早期积极的手术切除进行源头控制。广泛的手术切除可导致显著的软组织缺损,其可被毁容且难以闭合。最常见的闭合方法是裂层皮肤移植(STSG)。最近,除STSG外,还使用了自体皮肤细胞悬液(ASCS)技术,以提供更好的伤口愈合和闭合。这个病人伤口进展良好,followingFG,通过使用STSG的ASCS,尽管与伤口有关的挑战,解剖位置,合并症,尺寸,和病人的病史。
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