背景:中风后,由于身体表征的获得性缺陷,患者可能会改变对自己身体的感知。虽然这些变化可能会影响他们的生活质量和康复,在临床实践中没有对它们进行系统评估。这项研究的目的是提供更好的了解率,进化,以及对中风后上肢(UL)身体知觉(BPs)改变的恢复的影响。此外,我们将调查BP变更项目之间的关联,它们与感觉运动功能的关联,UL活动,大脑结构和连通性的损害。
方法:我们开发了一种名为ALPQ(受影响肢体感知问卷)的新工具来实现本研究目标。它评估了中风后对受影响的UL感知的主观改变,通过测量几个维度,即:偏瘫的失认症,偏瘫的无迟钝症,半乳牙病,躯体性araprenia,受影响的肢体的拟人化,物理特性修改的错觉(温度,体重,长度),虚幻的运动,多余或多余的肢体,UL断开,米索停搏液,和非自愿运动。这项研究结合了横截面和纵向设计。完整的数据样本将包括至少60名急性中风患者和100名亚急性中风患者。如果可能,患者随访至慢性期。进行补充评估以评估患者的感觉运动和认知功能以及UL活动,脑部病变将被分析。
结论:这项研究将更好地了解中风后的BPs改变:其速率和演变,以及它们与感觉运动缺陷的联系,认知概况和UL活动,脑损伤和恢复。最终,结果可以支持根据患者的UL感知个性化的康复策略,以最大限度地提高他们的康复。
背景:本研究的协议已于7月7日在开放科学框架上预先注册,2021年:https://osf.io/p6v7f。
BACKGROUND: Following a stroke, patients may suffer from alterations in the perception of their own body due to an acquired deficit in body representations. While such changes may impact their quality of life as well as recovery, they are not systematically assessed in clinical practice. This study aims at providing a better understanding of the rate, evolution, and impact on recovery of upper limb (UL) body perceptions (BPs) alterations following stroke. In addition, we will investigate associations among BPs alterations items, their associations with the sensorimotor functions, UL activity, damages in brain structure and connectivity.
METHODS: We developed a new tool named ALPQ (for Affected Limb Perception Questionnaire) to address the present study objectives. It assesses subjective alterations in the perception of the affected UL following stroke, by measuring several dimensions, namely: anosognosia for hemiplegia, anosodiaphoria for hemiplegia, hemiasomatognosia,
somatoparaphrenia, personification of the affected limb, illusion of modification of physical characteristics (temperature, weight, length), illusory movements, super- or undernumerary limb, UL disconnection, misoplegia, and involuntary movement. This study combines a cross-sectional and longitudinal design. The completed data sample will include a minimum of 60 acute and 100 sub-acute stroke patients. When possible, patients are followed up to the chronic stage. Complementary evaluations are administered to assess patients\' sensorimotor and cognitive functions as well as UL activity, and brain lesions will be analysed.
CONCLUSIONS: This study will provide a better understanding of BPs alterations following stroke: their rate and evolution, as well as their associations with sensorimotor deficit, cognitive profile and UL activity, brain lesions and recovery. Ultimately, the results could support the personalization of rehabilitation strategy according to patients\' UL perception to maximize their recovery.
BACKGROUND: The protocol for this study has been pre-registered on the Open Science Framework on July the 7th, 2021: https://osf.io/p6v7f .