Abstract:
Patients with a disturbed sense of limb ownership (DSO) offer a unique window of insight into the multisensory processes contributing to the sense of body ownership. A limited amount of past research has examined the role of sensory deficits in DSO, and even less is known regarding the role of patient self-reported somatosensory sensations in the pathogenesis of DSO. To address this lack of knowledge we first conducted a systematic scoping review following PRISMA-SR guidelines, examining current research into somatosensory deficits and patient self-reported somatosensory sensations in patients with DSO. Eighty studies, including 277 DSO patients, were identified. The assessment of sensory deficits was generally limited in scope and quality, and deficits in tactile sensitivity and proprioception were most frequently found. The reporting of somatosensory sensations was even less frequent, with instances of paraesthesia (pins-and-needles), stiffness/rigidity, numbness and warmth, coldness and heaviness amongst the deficits recorded. In a second part of the study, we sought to directly address the lack of evidence concerning the impact of patient self-reported somatosensory sensations in DSO by measuring DSO and self-reported somatosensory sensations in a large (n = 121) sample of right-hemisphere stroke patients including N = 65 with DSO and N = 56 hemiplegic controls. Results show that feelings of coldness and stiffness modulate DSO symptoms. Sense of heaviness and numbness are more frequent in patients with DSO but do not have a clear impact on disownership symptomology. Although preliminary, these results suggest a role of subjective sensations about the felt body in the sense of limb ownership.
摘要:
肢体所有权(DSO)受到干扰的患者提供了一个独特的窗口,可以了解有助于身体所有权感的多感官过程。过去的研究数量有限,研究了感觉缺陷在DSO中的作用,关于患者自我报告的体感感觉在DSO发病机理中的作用,甚至知之甚少。为了解决这种知识的缺乏,我们首先遵循PRISMA-SR指南进行了系统的范围审查,检查DSO患者的体感缺陷和患者自我报告的体感感觉的当前研究。八十项研究,包括277名DSO患者,已确定。感官缺陷的评估通常在范围和质量上受到限制,最常发现触觉敏感性和本体感觉缺陷。体感感觉的报告甚至更不频繁,带有感觉异常(别针)的实例,刚度/刚度,麻木和温暖,记录的赤字中的寒冷和沉重。在研究的第二部分,我们试图通过测量大量(n=121)右半球卒中患者的DSO和自我报告的体感感觉,包括N=65的DSO和N=56的偏瘫对照,来直接解决DSO患者自我报告的体感感觉影响的缺乏证据.结果表明,寒冷和僵硬的感觉可以调节DSO症状。DSO患者的沉重感和麻木感更为常见,但对失主症状学没有明显影响。虽然是初步的,这些结果表明,关于感觉身体的主观感觉在肢体所有权感中的作用。