目的:本研究的目的是评估精液参数之间的关系,全血细胞计数,精子图当天的激素水平。
方法:本研究纳入了230例患者的精液参数,这些患者在精子图当天接受了全血计数和激素水平的检查。根据活动精子总数(TMSC)对患者进行分组,精液参数,血象,组间比较激素水平。
结果:在中性粒细胞比率方面,组间无统计学差异,中性粒细胞,淋巴细胞,血小板计数,中性粒细胞与淋巴细胞之比(N/L),和血小板淋巴细胞比率(P/L)。然而,白细胞(WBC)和淋巴细胞计数与精子浓度呈微弱正相关(p=0.021,p=0.026),并且发现与WBC和中性粒细胞计数的运动性呈弱显着正相关(p=0.038,p=0.004)。发现TMSC>20m的患者的FSH水平低于TMSC<5m和5-10m的患者(p=0.004,p=0.022)。发现TMSC>20m的患者LH低于TMSC<5m的患者(p=0.048)。发现FSH和LH水平与精子浓度呈负相关,运动性,和TMSC(p<0.001,p=0.014)。
结论:在这项研究中,FSH之间存在显著的负相关,LH水平和精子浓度,运动性,TMSC。N/L和P/L不能作为精子质量的预测指标。结果WBC之间呈显著正相关,中性粒细胞计数,和精子参数鼓励研究人员使用更大的样本量和不同的炎症和激素标志物进行前瞻性随机对照试验。
OBJECTIVE: The aim of this study is to evaluate the relationship between semen parameters, complete blood count, and hormone levels on the day of spermiogram.
METHODS: Semen parameters of 230 patients who were examined for full blood count test and hormone levels on the day of spermiogram were included in the study. Patients were grouped according to the total motile sperm count (TMSC), semen parameters, hemogram, and hormone levels were compared between groups.
RESULTS: No statistically significant difference was found between groups in neutrophil ratios, neutrophil, lymphocyte, platelet counts, neutrophile-to-lymphocyte ratio (N/L), and platelet-to-lymphocyte ratio (P/L). However, white blood cell (WBC) and lymphocyte counts were weakly positively correlated with sperm concentration (p=0.021, p=0.026), and a weakly significant positive correlation was found with WBC and neutrophil count for motility (p=0.038, p=0.004). FSH level was found to be lower in cases with TMSC >20 m than those with TMSC <5 m and 5-10 m (p=0.004, p=0.022). LH was found to be lower in cases with TMSC >20 m than those with TMSC <5 m (p=0.048). A negative correlation was found for both FSH and LH levels with sperm concentration, motility, and TMSC (p<0.001, p=0.014).
CONCLUSIONS: In this study, a significant negative correlation was demonstrated between FSH, LH levels and sperm concentration, motility, TMSC. N/L and P/L cannot be used as predictive markers of sperm quality. The results of a significant positive correlation between WBC, neutrophil counts, and sperm parameters encourage researchers to conduct prospective randomized controlled trials with larger sample sizes and different inflammatory and hormonal markers.