关键词: DNA fragmentation ejaculatory abstinence semen parameters sexual abstinence sperm parameters

Mesh : Male Humans Sexual Abstinence Ejaculation / physiology Spermatozoa / physiology Sperm Motility Sperm Count Randomized Controlled Trials as Topic Semen Analysis DNA Fragmentation Time Factors

来  源:   DOI:10.3389/fendo.2024.1373426   PDF(Pubmed)

Abstract:
UNASSIGNED: This study aimed to investigate the effects of ejaculatory abstinence on sperm parameters.
UNASSIGNED: This analysis was registered in PROSPERO (CRD42023472124). We performed a search on PubMed using the following text terms: ((\"sperm parameters\" OR \"sperm analysis\" [Mesh]) AND (\"sperm DNA fragmentation\" OR \"DNA fragmentation\" [Mesh]) AND (\"sexual abstinence\" [Mesh] OR \"abstinence\")) and an advanced search in Scopus using the terms (\"sperm parameters\" OR \"sperm parameters\" OR \"DNA fragmentation\") AND (\"abstinence\"). The sperm parameters that were investigated were sperm volume, total sperm motility, progressive sperm motility, sperm concentration, sperm morphology, and sperm DNA fragmentation (SDF). A two-day cut-off as a \"short\" or \"long\" abstinence period has been defined.
UNASSIGNED: Thirteen studies published between 2013 and 2022 were included in this meta-analysis. A total of 2,315 patients, ranging from 6 to 836 from each cohort, were enrolled in the study. We showed that longer abstinence time was associated with greater sperm concentration (mean difference [MD]: 8.19; p <0.01), sperm volume (MD: 0.96; p <0.01), and higher SDF (MD: 3.46; p <0.01), but lower progressive sperm motility (MD: -1.83; p <0.01). Otherwise, no statistically significant difference was observed in patients with longer vs. shorter abstinence times regarding total sperm motility (MD: -1.83; p = 0.06). Meta-regression analysis showed that days of abstinence were positively and linearly related to sperm concentration (slope: 3.74; p <0.01) and SDF (slope: 0.65; p = 0.044).
UNASSIGNED: According to our data, short ejaculatory abstinence is associated with better sperm quality. Indeed, a higher percentage of progressive sperm motility and lower levels of SDF have been reported in a short abstinence cohort. In contrast, the long abstinence group reported a higher sperm concentration.
UNASSIGNED: https://www.crd.york.ac.uk/PROSPERO/, identifier CRD42023472124.
摘要:
本研究旨在研究射精禁欲对精子参数的影响。
该分析已在PROSPERO(CRD42023472124)中注册。我们使用以下文本术语在PubMed上进行了搜索:((\“精子参数\”或\“精子分析\”[网格])和(\“精子DNA碎片\”或\“DNA碎片\”[网格])和(\“性禁欲\”[网格]或\“禁欲\”),并使用术语在Scopus中进行了高级搜索研究的精子参数是精子体积,精子总运动性,进行性精子运动性,精子浓度,精子形态学,和精子DNA片段化(SDF)。已将两天的禁欲期定义为“短”或“长”禁欲期。
2013年至2022年发表的13项研究纳入了这项荟萃分析。共有2315名患者,每个队列从6到836不等,参加了这项研究。我们表明,更长的禁欲时间与更高的精子浓度相关(平均差异[MD]:8.19;p<0.01),精子体积(MD:0.96;p<0.01),和更高的SDF(MD:3.46;p<0.01),但进行性精子运动性较低(MD:-1.83;p<0.01)。否则,在比较长的患者中没有观察到统计学上的显著差异。关于总精子运动的禁欲时间较短(MD:-1.83;p=0.06)。Meta回归分析显示,戒断天数与精子浓度(斜率:3.74;p<0.01)和SDF(斜率:0.65;p=0.044)呈正相关。
根据我们的数据,短暂的射精禁欲与更好的精子质量有关。的确,据报道,在一个短期禁欲队列中,有较高比例的进行性精子运动性和较低水平的SDF.相比之下,长期禁欲组的精子浓度较高。
https://www.crd.约克。AC.英国/PROSPERO/,标识符CRD42023472124。
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