Sclérothérapie

  • 文章类型: Case Reports
    背景:硬化疗法在肝硬化患者中由于胃食管静脉曲张破裂(GOV)引起的上消化道出血(UGB)的情况下被广泛用作挽救生命的治疗选择,尤其是当存在门体分流时。这种内窥镜技术会带来许多并发症,包括全身性和非血栓性肺栓塞(PE)。虽然已经描述了GOV硬化治疗后的多种肺实质表现,据我们所知,尚未描述孤立的可疑肺结节。
    方法:我们报告了一例55岁有大量吸烟史的男性,他被转诊到我们的肺部诊所检查孤立性肺结节。由于两个月前GOV破裂,他患有肝硬化并有大量UGB病史。他通过注射3ccHistoacryl/lipiodole溶液进行硬化治疗。内镜后阶段无明显变化。两个月后进行的胸部和腹部增强CT扫描显示右上叶结节,即使在这一点上,患者完全无症状。这归因于硬化疗法继发的非血栓性PE,这是由于在2个月的随访中进行的CT扫描中结节完全消退。在这一点上,他的病情不需要任何进一步的治疗。
    结论:孤立性肺结节是GOV硬化治疗后PE的影像学表现之一。对这种不寻常的放射学表现的认识和放射学随访可以防止不必要的活检。
    BACKGROUND: Sclerotherapy is a widely used as a lifesaving therapeutic option in cases of upper gastrointestinal bleeding (UGB) due to ruptured gastro-esophageal varices (GOV) in cirrhotic patients, especially when there exists a portosystemic shunt. This endoscopic technique can entail many complications, including systemic and non-thrombotic pulmonary embolism (PE). While multiple pulmonary parenchymal manifestations have been described following sclerotherapy of GOV, to our knowledge no solitary suspicious pulmonary nodule has been described.
    METHODS: We report the case of 55-year-old man with heavy smoking history who was referred to our pulmonary clinic for work-up of a solitary pulmonary nodule. He was known to have liver cirrhosis with history of massive UGB due to rupture of GOV two months before. He was treated with sclerotherapy by injecting a 3 cc of Histoacryl/lipiodole solution. The post- endoscopic phase was unremarkable. An enhanced CT scan of chest and abdomen performed two months later showed a right upper lobe nodule, even though at that point, the patient was completely asymptomatic. This was ascribed to non-thrombotic PE secondary to sclerotherapy due to complete resolution of the nodule on a CT scan carried out at 2-month follow-up. At that point, his condition did not require any further treatment.
    CONCLUSIONS: Solitary pulmonary nodule is one of the radiologic manifestations of PE subsequent to sclerotherapy of GOV. Awareness and radiologic follow-up of this unusual radiologic presentation may prevent unnecessary biopsies.
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  • 文章类型: English Abstract
    目的:概述法国子宫内膜瘤的治疗方法。
    方法:我们在2021年10月至2022年1月期间对子宫内膜瘤的管理方法进行了全国性的调查。这项研究是通过向用于治疗子宫内膜异位症的手术中心(n=62)和辅助生殖技术(ART)中心(n=102)发送的两份问卷进行的。
    结果:在调查结束时,来自所联系中心的39/62(62.9%)手术团队给予了响应,51/102(50.0%)MAP中心给予了响应。腹腔镜膀胱切除术是近三分之二的手术团队(61%)在没有已知的不孕症时最常用的技术。而这是仅14%的ART团队最常见的技术。相反,在超过一半的ART团队(56%)中,超声引导下的硬化疗法是最常见的技术,在手术团队中,仅有8%的患者是最常见的技术.如果复发,49%的手术团队会选择超声引导下的硬化治疗。在IVF之前,73%的MPA团队表示,他们“很少”治疗子宫内膜瘤。
    结论:我们的研究结果表明,在法国,子宫内膜瘤的治疗在不同中心之间的实践中存在一定的差异,这取决于是否存在不孕症。
    To present an overview of French practices for the management of endometriomas.
    We carried out a nationwide survey of practices concerning the management of endometriomas between October 2021 and January 2022. This study was carried out by means of two questionnaires sent to surgical centers used to treat endometriosis (n=62) and to Assisted Reproductive Technology (ART) centers (n=102).
    At the end of the survey, 39/62 (62.9%) surgical teams from the centers contacted had given a response and 51/102 (50.0%) from ART centers. Laparoscopic cystectomy was the technique most frequently used by almost two thirds of the surgical teams (61%) when there was no known infertility, whereas it was the most common technique for only 14% of the ART teams. On the contrary, ultrasound-guided sclerotherapy was the most frequent technique for more than half of the ART teams (56%) and for only 8% of the surgical teams. In case of recurrence, 49% of surgical teams would choose ultrasound-guided sclerotherapy. Prior to IVF, 73% of ARP teams stated that they \'rarely\' treated endometriomas.
    The results of our study show a certain variability in practices between different centers and depending on the presence or absence of infertility for the management of endometriomas in France.
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  • 文章类型: Letter
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  • 文章类型: Journal Article
    目的:研究临床左精索静脉曲张(CLV)顺行硬化治疗(AS)后精子参数的早期术后过程,并验证治疗的有效性和安全性。
    方法:男性CLV患者的单中心回顾性观察研究,这对夫妇的原发性或继发性不孕症的医疗辅助生育中心顾问。所有患者均通过阴囊入路进行SA手术。在6周的临床和超声检查后,在手术3-6个月时进行对照精子图检查.分析了以下参数:精子计数,运动性,正常形式的百分比,和活动精子总数(“活动精子总数”[TMSC])。
    结果:该研究涉及138名精子改变的男性(中位年龄33岁)。所有患者均受益于CLV的AS。未观察到Clavian并发症>1。术后控制显示所有精子图参数显著改善,中位进展为40%的计数(55vs32×106),浓度的80%(20.3vs11.1×106/ml),30%的运动性(34.7%vs26.5%),正常形式百分比的60%(4.0vs2.5%)和75%的TMSC(41.5vs23%),7×106)(p<0.005)。
    结论:SA是治疗CLV和改善精子参数生育力指标的有效且安全的技术。我们的结果表明,这种治疗方法可以推荐给患有CLV的不育男性,以治疗这对夫妇的不孕症。
    方法:3.
    OBJECTIVE: Study the early postoperative course of sperm parameters after antegrade sclerotherapy (AS) of clinical left varicocele (CLV) in men consulting for infertility with sperm disruption, and to validate the efficacy and safety of treatment.
    METHODS: Monocentric retrospective observational study of men with CLV, consultant in medically assisted procreation center for primary or secondary infertility of the couple. All patients were operated by SA via scrotal approach. After clinical and ultrasound checks at 6 weeks, a control spermogram was performed at 3-6 months of surgery. The following parameters were analyzed: sperm count, motility, percent of normal form, and total number of motile sperm (\"total motile sperm count\" [TMSC]).
    RESULTS: The study involved 138 men (median age 33 years) with sperm alteration. All patients benefited from AS of their CLV. No Clavian complication > 1 was observed. Postoperative control demonstrated a significant improvement in all spermogram parameters, with a median progression of 40% of the count (55 vs 32×106), 80% of the concentration (20.3 vs 11.1×106/ml), 30% of the motility (34.7% vs 26.5%), 60% of the normal form percentage (4.0 vs 2.5%) and the 75% TMSC (41.5 vs 23%), 7×106) (p<0.005).
    CONCLUSIONS: SA is an effective and safe technique for treating CLV and improving sperm parameters fertility indicators. Our results suggest that this treatment may be recommended to infertile men with CLV in the management of infertility of the couple.
    METHODS: 3.
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  • 文章类型: Journal Article
    Surgical management of ovarian endometrioma is most often part of a global approach of endometriosis pathology. Isolated endometrioma are rare. Laparoscopic cystectomy is the gold standard for surgical management of endometrioma. Nevertheless, this technique impacts the ovarian function. The hemostasis of the ovarian cyst bed should be performed to conserve the ovarian stroma. Ultrasonography-guided cyst aspiration, laparoscopic drainage and simple bipolar coagulation are not recommended as first line of treatment. Based on the actual literature, we cannot state the place of laser-vaporization and plasma-energy ablation in surgical management. Ethanol sclerotherapy could be an alternative to treat recurrent endometrioma. Uncompleted surgical removal of endometriosis lesions increases the recurrence rate. Endometriosis management should take into account the research and treatment of all the pelvic lesion, especially before surgical management of endometrioma. In this context, the evaluation of ovarian reserve could be useful before surgery.
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  • 文章类型: Journal Article
    Management of vascular malformations and vascular tumors has recently been maximized by the establishment of an accurate clinical and histological classification and by the development of multidisciplinary expert consultations. Head and neck localizations of venous malformations are common, thus maxillo-facial surgeons should be aware of the characteristics of this pathology and the principles of its management. Diagnosis is mainly clinical and must be certified by Doppler-ultrasonography and contrast enhanced magnetic resonance imaging with T2 fat-saturation sequence. Therapeutic decision depends on the volume of the lesion, and on functional, cosmetic and psychological complaints. Sclerotherapy is now the preferred treatment of head and neck venous malformations. It is performed in specialized interventional radiology units by intralesional injections of sclerosing solution under fluoroscopic guidance. Surgery is useful in some cases, either on its own or following sclerotherapy. In case of bulky lesion, it is necessary to search for and prevent a severe coagulopathy before planning any intervention.
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  • 文章类型: Journal Article
    These guidelines proposed by the French Society of Vascular Medicine define the optimal environment for vascular medicine practice: outpatient clinic; equipment, layout and maintenance of the care center; infection risk prevention (hand hygiene, individual protective measures, exposure to blood, ultrasound apparatus, etc.); common interventions and techniques (liquid and foam sclerotherapy, endovenous thermal treatments). These guidelines do not include phlebectomy and use of ultrasound contrast agents.
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  • 文章类型: Journal Article
    OBJECTIVE: The main objective was to investigate the long-term clinical and radiological effectiveness/safety of ethanol sclerotherapy for treating simple kidney cysts.The secondary objective was to evaluate the effectiveness of a second alcohol treatment after 24 hours of drainage for large cysts.
    METHODS: A retrospective study was carried out from January 2005 to March 2012 on 24 patients with simple kidney cysts treated by percutaneous ethanol sclerotherapy during ambulatory surgery. Therapeutic success was defined as symptom resolution and regression of cyst size by > 60%. Incomplete regression was defined as a decrease between 50 and 60% and a recurrence as a residual size > 50%. Drainage was left in place for 24 hours for patients with a cyst > 900 cm(3) and a second alcohol treatment was performed the next day. All patients were invited for ultrasound follow up as part of the study.
    RESULTS: Treatment success was observed in 91.6% of patients. Two patients had incomplete regression. No recurrence was observed. No intraoperative or postoperative complications were found.
    CONCLUSIONS: Sclerotherapy for simple kidney cysts is a safe and effective procedure that can be performed under local anesthesia and an outpatient setting in most cases. Systematic drainage for 24 hours followed by a second alcohol treatment may reduce the risk of recurrence for large cysts.
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  • 文章类型: Editorial
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