关键词: Infertility Infertilité Sclerotherapy Sclérothérapie Spermogram Spermogramme Traitement Treatment Varicocele Varicocèle

Mesh : Adult Humans Infertility, Male / etiology therapy Male Middle Aged Retrospective Studies Sclerotherapy / adverse effects methods Semen Analysis Treatment Outcome Varicocele / complications pathology therapy Young Adult

来  源:   DOI:10.1016/j.purol.2020.02.010   PDF(Sci-hub)

Abstract:
OBJECTIVE: Study the early postoperative course of sperm parameters after antegrade sclerotherapy (AS) of clinical left varicocele (CLV) in men consulting for infertility with sperm disruption, and to validate the efficacy and safety of treatment.
METHODS: Monocentric retrospective observational study of men with CLV, consultant in medically assisted procreation center for primary or secondary infertility of the couple. All patients were operated by SA via scrotal approach. After clinical and ultrasound checks at 6 weeks, a control spermogram was performed at 3-6 months of surgery. The following parameters were analyzed: sperm count, motility, percent of normal form, and total number of motile sperm (\"total motile sperm count\" [TMSC]).
RESULTS: The study involved 138 men (median age 33 years) with sperm alteration. All patients benefited from AS of their CLV. No Clavian complication > 1 was observed. Postoperative control demonstrated a significant improvement in all spermogram parameters, with a median progression of 40% of the count (55 vs 32×106), 80% of the concentration (20.3 vs 11.1×106/ml), 30% of the motility (34.7% vs 26.5%), 60% of the normal form percentage (4.0 vs 2.5%) and the 75% TMSC (41.5 vs 23%), 7×106) (p<0.005).
CONCLUSIONS: SA is an effective and safe technique for treating CLV and improving sperm parameters fertility indicators. Our results suggest that this treatment may be recommended to infertile men with CLV in the management of infertility of the couple.
METHODS: 3.
摘要:
目的:研究临床左精索静脉曲张(CLV)顺行硬化治疗(AS)后精子参数的早期术后过程,并验证治疗的有效性和安全性。
方法:男性CLV患者的单中心回顾性观察研究,这对夫妇的原发性或继发性不孕症的医疗辅助生育中心顾问。所有患者均通过阴囊入路进行SA手术。在6周的临床和超声检查后,在手术3-6个月时进行对照精子图检查.分析了以下参数:精子计数,运动性,正常形式的百分比,和活动精子总数(“活动精子总数”[TMSC])。
结果:该研究涉及138名精子改变的男性(中位年龄33岁)。所有患者均受益于CLV的AS。未观察到Clavian并发症>1。术后控制显示所有精子图参数显著改善,中位进展为40%的计数(55vs32×106),浓度的80%(20.3vs11.1×106/ml),30%的运动性(34.7%vs26.5%),正常形式百分比的60%(4.0vs2.5%)和75%的TMSC(41.5vs23%),7×106)(p<0.005)。
结论:SA是治疗CLV和改善精子参数生育力指标的有效且安全的技术。我们的结果表明,这种治疗方法可以推荐给患有CLV的不育男性,以治疗这对夫妇的不孕症。
方法:3.
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