■本研究旨在通过分析孢子丝菌病的流行病学特征,提高对孢子丝菌病的认识,临床表现,真菌学特征,和中国东部疾病的病理特征。
■收集并回顾性分析了在皮肤科门诊20年间诊断为皮肤孢子丝菌病的49例患者的临床资料。分析包括患者的人口统计学,职业,临床类型,病变部位,误诊率,实验室调查,治疗和结果。
■该研究包括22名男性和27名女性患者,平均年龄52.4岁。农民(42.86%)和体力劳动者(28.57%)的感染风险较高。最常见的临床类型是淋巴皮肤(30.61%)和固定(69.39%),主要影响面部和上肢。误诊为其他感染性皮肤病35例(71.43%)。真菌培养和组织病理学检查是重要的诊断工具。口服伊曲康唑治疗3个月可使大多数患者的皮肤损伤得到缓解和消退,尽管经历了一些复发。
■皮肤孢子丝菌病主要影响从事农业和体力劳动的个人,以淋巴皮肤型和固定型为主要临床表现。高误诊率强调了早期识别的重要性,准确的诊断和规范化的治疗对孢子丝菌病的预后和治愈。真菌培养和组织病理学检查对诊断至关重要。口服伊曲康唑是一种有效的治疗选择。
UNASSIGNED: This study aimed to improve the understanding of
sporotrichosis by analyzing the epidemiological characteristics, clinical manifestations, mycological features, and pathological characteristics of the disease in eastern China.
UNASSIGNED: Clinical data of 49 patients diagnosed with cutaneous
sporotrichosis in dermatology clinics over a 20-year period were collected and analyzed retrospectively. The analysis included patient demographics, occupations, clinical types, lesion sites, misdiagnosis rates, laboratory investigations, treatment and outcomes.
UNASSIGNED: The study included 22 male and 27 female patients, with a mean age of 52.4 years. Farmers (42.86%) and manual workers (28.57%) had a higher risk of infection. The most common clinical types were lymphocutaneous (30.61%) and fixed (69.39%), predominantly affecting the face and upper limbs. Misdiagnosis as other infectious skin diseases occurred in 35 patients (71.43%). Fungal culture and histopathological examination were important diagnostic tools. Treatment with oral itraconazole for three months led to relief and regression of the skin lesions in most patients, although a few experienced recurrences.
UNASSIGNED: Cutaneous
sporotrichosis mainly affects individuals working in agriculture and manual labour, with lymphocutaneous and fixed types being the predominant clinical manifestations. The high misdiagnosis rate emphasizes the importance of early recognition, accurate diagnosis and standardized treatment for the prognosis and cure of
sporotrichosis. Fungal culture and histopathological examination are essential for diagnosis, and oral itraconazole is an effective treatment option.