Rib fracture

肋骨骨折
  • 文章类型: Journal Article
    目的:这项工作的目的是评估和验证前胸壁的AO/OTA分类,这里特别是肋软骨。
    方法:研究设计是对2010-2016年胸壁骨折住院患者的回顾性分析。这导致一组n=124名患者。所有的前胸壁骨折根据其位置进行分类,根据AO分类的脱位和骨折类型。对可能的亚型进行了分析。
    结果:29.0%(36)的患者有肋软骨骨折。36例患者中有23例(64%)有多处骨折,单个骨折总数为94。53.2%(50)的骨折位于右半胸部,左半胸部占46.8%(44)。95.7%(90)的骨折为A型骨折,4.3%(4)为C型骨折。没有B骨折。C骨折也仅由A骨折(AA骨折)组成。59.6%(56)的骨折显示脱位。骨软骨撕脱性骨折(22.3%(21))或胸肋交界处撕脱性骨折(8.5%(8))占30.9%(29)。
    结论:肋软骨明显不显示典型的B骨折,正如我们从长骨干骨折中所知道的那样。我们在随附的手稿中编制了结构化分析,并验证了分类建议。总之,我们根据我们的数据提出了对分类建议的调整,将B型骨折重新定义为骨软骨关节骨折.
    OBJECTIVE: Aim of this work was the evaluation and validation of the AO/OTA classification of the anterior chest wall, here especially for the rib cartilage.
    METHODS: Study design was a retrospective analysis of patients who were hospitalized with fractures of the thoracic wall in the years 2010-2016. This resulted in a collective of n = 124 patients. All fractures of the anterior chest wall were classified according to their location, dislocation and fracture type according to the AO classification. An analysis of possible subtypes was carried out.
    RESULTS: 29.0% (36) of the patients had fractures of the rib cartilage. 23 of the 36 (64%) patients had multiple fractures, the total number of single fractures amounted to 94. 53.2% (50) of these fractures were in the right hemithorax, 46.8% (44) in the left hemithorax. 95.7% (90) of the fractures were A-fractures, 4.3% (4) were C-fractures. There were no B fractures. The C fractures also consisted exclusively of A fractures (AA fractures). 59.6% (56) of the fractures showed a dislocation. 30.9% (29) were avulsion fractures of either the osteochondral (22.3% (21)) or the sternocostal junction (8.5% (8)).
    CONCLUSIONS: The costal cartilage obviously does not show typical B fractures as we know them from shaft fractures of long bones. We have compiled a structured analysis in the attached manuscript and validated the classification proposal. In conclusion, we propose an adaptation of the classification proposal based on our data with redefining type B fractures as fractures of the osteochondral joints.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

    求助全文

  • 文章类型: Journal Article
    背景:肋骨骨折是立体定向放疗(SBRT)后已知的并发症。患者相关参数对于提供患者量身定制的风险估计至关重要,然而,与剂量学参数相比,它们对肋骨骨折的影响记录较少。这项研究旨在基于患者相关和剂量参数来预测SBRT后局部非小细胞肺癌(NSCLC)患者肋骨骨折的风险,其中死亡是一种竞争风险。
    方法:总共,2010-2020年间,在欧登塞大学医院接受SBRT治疗的602例局限性NSCLC患者,丹麦也包括在内。所有患者均接受具有45-66Gray(Gy)/3个分数的SBRT。使用单词嵌入模型在CT扫描中识别出肋骨骨折。累积发生率函数基于特定原因的Cox风险模型,并基于使用50个引导程序进行的交叉验证模型似然性进行变量选择。
    结果:总计,19%的患者经历了肋骨骨折。从SBRT后6-54个月,肋骨骨折的累积风险迅速增加。女性性别,骨密度,接近肋骨的最大剂量,V30和V40到肋,肿瘤总体积,在单变量分析中,平均肺剂量与肋骨骨折风险显著相关。最终的多变量模型由V20和V30到肋骨和平均肺剂量组成。
    结论:女性和男性患者的低骨密度是肋骨骨折风险的重要预测因素。在接受SBRT治疗的局部NSCLC患者中,预测累积肋骨骨折风险为19%的最终模型不包含患者相关参数。这表明剂量测定参数是主要驱动因素。
    BACKGROUND: Rib fracture is a known complication after stereotactic body radiotherapy (SBRT). Patient-related parameters are essential to provide patient-tailored risk estimation, however, their impact on rib fracture is less documented compared to dosimetric parameters. This study aimed to predict the risk of rib fractures in patients with localized non-small cell lung cancer (NSCLC) post-SBRT based on both patient-related and dosimetric parameters with death as a competing risk.
    METHODS: In total, 602 patients with localized NSCLC treated with SBRT between 2010-2020 at Odense University Hospital, Denmark were included. All patients received SBRT with 45-66 Gray (Gy)/3 fractions. Rib fractures were identified in CT-scans using a word embedding model. The cumulative incidence function was based on cause-specific Cox hazard models with variable selection based on cross-validation model likelihood performed using 50 bootstraps.
    RESULTS: In total, 19 % of patients experienced a rib fracture. The cumulative risk of rib fracture increased rapidly from 6-54 months post-SBRT. Female gender, bone density, near max dose to the rib, V30 and V40 to the rib, gross tumor volume, and mean lung dose were significantly associated with rib fracture risk in univariable analysis. The final multi-variable model consisted of V20 and V30 to the rib and mean lung dose.
    CONCLUSIONS: Female gender and low bone density in male patients are significant predictors of rib fracture risk. The final model predicting cumulative rib fracture risk of 19 % in patients with localized NSCLC treated with SBRT contained no patient-related parameters, suggesting that dosimetric parameters are the primary drivers.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

    求助全文

  • 文章类型: Case Reports
    肺栓塞(PE)是由阻塞肺动脉的血块引起的危及生命的疾病,导致肺部的血液供应减少。如果不治疗,PE是一种高风险的诊断,发病率和死亡率相当高。该病例强调了与创伤相关的PE风险增加,并强调了这种鉴别诊断在报告身体创伤后呼吸困难的患者中的重要性。了解导致创伤患者发生PE的危险因素和过程对于准确诊断和治疗至关重要。
    Pulmonary embolism (PE) is a life-threatening illness caused by a blood clot obstructing a pulmonary artery, resulting in decreased blood supply to the lungs. PE is a high-stakes diagnosis with considerable morbidity and death if left untreated. This case emphasizes the increased risk of PE associated with trauma and stresses the importance of this differential diagnosis in patients who report dyspnea following physical trauma. Understanding the risk factors and processes that contribute to PE in trauma patients is critical for accurate diagnosis and treatment.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Journal Article
    背景:肋骨骨折(SSRF)的手术稳定与较低的死亡率和较少的并发症相关。这项研究评估了接受SSRF的决定是否与年龄有关,种族,种族,和保险状况,并评估相关的临床结果。
    方法:这项回顾性分析包括2016年至2020年在创伤质量改善计划中接受SSRF的年龄≥45岁的肋骨骨折患者。种族,种族,并收集了保险状态。将年龄分为两组:45-64和65。结果包括呼吸机相关性肺炎,计划外气管插管,急性呼吸窘迫综合征,住院死亡率,严重并发症后未能抢救(FTR),和呼吸系统并发症后的FTR。Logistic回归模型适合评估结果,控制性别,身体质量指数,伤害严重程度评分,连击胸,慢性阻塞性肺疾病,充血性心力衰竭,和吸烟。
    结果:两千八百三十九名年龄在45-64岁的患者和1828名年龄在65岁以上的患者接受了SSRF。这些组之间的临床结果没有显着差异。分析显示SSRF与呼吸机相关性肺炎,计划外插管,急性呼吸窘迫综合征,住院死亡率,严重并发症后的FTR,呼吸系统并发症后或FTR不因年龄而异(P>0.05)。黑色(比值比[OR]0.67;95%置信区间[CI]:0.59-0.77;P<0.001),西班牙裔(OR0.80;95%CI:0.71-0.91;P<0.001),和医疗补助(OR=0.85;95%CI=0.76-0.95;P=0.005)患者接受SSRF的可能性较小。
    结论:在接受SSRF的45-64岁和≥65岁的成年人之间,临床结果没有差异。年龄较大不应排除患者接受SSRF。需要进一步的工作来改善布莱克的利用率不足,西班牙裔和医疗补助患者。
    BACKGROUND: Surgical stabilization of rib fractures (SSRF) is associated with lower rates of mortality and fewer complications. This study evaluates whether the decision to undergo SSRF is associated with age, race, ethnicity, and insurance status and assesses associated clinical outcomes.
    METHODS: This retrospective analysis included patients ≥45 y old with rib fractures who underwent SSRF in the Trauma Quality Improvement Program from 2016 to 2020. Race, ethnicity, and insurance statuses were collected. Age in years was dichotomized into two groups: 45-64 and 65+. Outcomes included ventilator-associated pneumonia, unplanned endotracheal intubation, acute respiratory distress syndrome, in-hospital mortality, failure to rescue (FTR) after major complications, and FTR after respiratory complications. Logistic regression models were fit to evaluate outcomes, controlling for gender, body mass index, Injury Severity Score, flail chest, chronic obstructive pulmonary disease, congestive heart failure, and smoking.
    RESULTS: Two thousand eight hundred thirty-nine patients aged 45-64 and 1828 patients aged 65+ underwent SSRF. No significant difference in clinical outcomes was noted between these groups. Analysis showed that the association of SSRF with ventilator-associated pneumonia, unplanned intubation, acute respiratory distress syndrome, in-hospital mortality, FTR after a major complication, or FTR after a respiratory complication did not vary by age (P > 0.05). Black (odds ratio [OR] 0.67; 95% confidence interval [CI]: 0.59-0.77; P < 0.001), Hispanic (OR 0.80; 95% CI: 0.71-0.91; P < 0.001), and Medicaid (OR = 0.85; 95% CI = 0.76-0.95; P = 0.005) patients were less likely to receive SSRF.
    CONCLUSIONS: No differences in clinical outcomes were measured between adults aged 45-64 and ≥65 who underwent SSRF. Older age should not preclude patients from receiving SSRF. Further work is needed to improve underutilization in Black, Hispanic and Medicaid patients.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

    求助全文

  • 文章类型: Case Reports
    尽管立体定向放射治疗(SBRT)是I期非小细胞肺癌(NSCLC)的治愈性治疗选择,在超过10年的延长随访期间,关于胸壁(CW)毒性的数据有限.我们报告了在SBRT治疗周围型肺癌13年后观察到的骨肿瘤样CW肿块病变伴病理性肋骨骨折的不寻常病例。尽管最初怀疑是辐射诱导的肉瘤,随后的切开活检显示没有恶性肿瘤的迹象,并明确诊断为骨坏死。因此,需要超过10年的长期观察,以确定SBRT后的晚期慢性并发症.
    Although stereotactic body radiotherapy (SBRT) is a curative treatment option for stage I non-small cell lung cancer (NSCLC), limited data are available regarding chest wall (CW) toxicities during an extended follow-up of over 10 years. We report an unusual case of a bone tumor-like CW mass lesion with pathological rib fractures observed 13 years after SBRT for peripheral lung cancer. Despite the initial suspicion of radiation-induced sarcoma, a subsequent incisional biopsy revealed no evidence of malignancy, and a definitive diagnosis of osteonecrosis was made. Thus, long-term observation of over 10 years is required to identify late chronic complications following SBRT.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

    求助全文

  • 文章类型: Journal Article
    肋骨骨折是最常见的钝性损伤之一,约占所有创伤患者的10%和胸部损伤的60%。多处肋骨骨折,尤其是连击胸,由于失去肋骨支撑,会导致局部胸壁软化,导致矛盾的呼吸,剧烈疼痛,伴随肺挫伤的可能性很高。
    这项研究调查了一种新型聚合物材料肋骨内固定器的机械性能,为其临床使用提供了理论数据。
    我们对20只新鲜的尾鳍羊肋骨进行了体外力学测试,在四个随机分配的组中使用不同的骨折模型(每组五根肋骨)。使用非破坏性三点弯曲评估固定器,扭转,和单边压缩试验,结果平均。此外,有限元分析比较了聚合物固定器和钛合金肋板在弯曲和扭转试验中的应力和应变。
    体外测试表明,聚合物固定器有效地处理了最大载荷,而不会增加超过一定位移。通过有限元分析进行的弯曲和扭转试验表明,与钛合金板(219.88MPa和46.47MPa)相比,聚合物材料的最大等效应力(84.455MPa和14.426MPa)较低。
    聚合物肋骨固定器显示出足够的强度用于肋骨骨折固定,并且在弯曲和扭转测试中与钛合金板相比,在应力管理方面均优于钛合金板,支持其潜在的临床应用。
    UNASSIGNED: Rib fractures are one of the most common blunt injuries, accounting for approximately 10% of all trauma patients and 60% of thoracic injuries. Multiple rib fractures, especially flail chest, can cause local chest wall softening due to the loss of rib support, leading to paradoxical breathing, severe pain, and a high likelihood of accompanying lung contusions.
    UNASSIGNED: This study investigates the mechanical properties of a new polymer material rib internal fixator to provide theoretical data for its clinical use.
    UNASSIGNED: We conducted in vitro mechanical tests on 20 fresh caudal fin sheep ribs, using different fracture models across four randomly assigned groups (five ribs per group). The fixators were assessed using non-destructive three-point bending, torsion, and unilateral compression tests, with results averaged. Additionally, finite element analysis compared stress and strain in the polymer fixators and titanium alloy rib plates during bending and torsion tests.
    UNASSIGNED: In vitro tests showed that the polymer fixators handled loads effectively up to a maximum without increase beyond a certain displacement. Bending and torsion tests via finite element analysis showed the polymer material sustained lower maximum equivalent stresses (84.455 MPa and 14.426 MPa) compared to titanium alloy plates (219.88 MPa and 46.47 MPa).
    UNASSIGNED: The polymer rib fixator demonstrated sufficient strength for rib fracture fixation and was superior in stress management compared to titanium alloy plates in both bending and torsion tests, supporting its potential clinical application.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

    求助全文

  • 文章类型: Journal Article
    肋骨扩张的开胸手术仍然是复杂手术的首选方法。在此方法中,肋骨骨折被认为是频繁的非自愿事件。但其实际发病率尚未得到充分调查。在这项研究中,我们评估了开胸手术后肋骨骨折的发生率,可能的危险因素以及与术后疼痛和并发症的关系。我们回顾性分析了2016年1月至2023年6月接受侧方开胸手术的单机构患者的病历。排除标准是创伤性病因和骨质疏松症病史。通过手术报告或术后胸部X光检查来检索肋骨骨折的存在。通过视觉模拟量表评估手术后的基底和诱发疼痛。考虑的术后30天并发症是肺不张,需要内窥镜支气管抽吸术,肺炎和胸腔积液。在研究期间,共有367例连续患者接受了开胸手术。中位年龄为68岁(四分位距60-75岁)。在179/367(48.8%)患者中发现肋骨骨折。发病率在整个年份中没有显着变化(p=0.98)。开胸术后发生肋骨骨折的风险与年龄大于中位数(p=0.003)显著相关。肋骨骨折的存在与术后48h诱发的疼痛明显升高有关(p=0.039)和更高的并发症发生率(32/179vs20/188;p=0.047)。我们的研究表明,肋骨骨折发生在几乎一半的开胸手术中。老年患者更容易发生这种事件,这与诱发的术后疼痛增加和术后并发症的发生率显着相关。
    Thoracotomy with rib spreading still remains the preferred approach for complex surgery. Rib fracture is considered a frequent involuntary event during this approach, but its real incidence has not been adequately investigated yet. In this study, we evaluated the incidence of rib fracture after thoracotomy, the possible risk factors and the relationship with post-operative pain and complications. We retrospectively analyzed the medical records of single-institution patients submitted to lateral thoracotomy from January 2016 to June 2023. Exclusion criteria were traumatic etiology and a medical history of osteoporosis. The presence of rib fracture was retrieved by surgical reports or post-operative chest X-ray. Basal and evoked pain after surgery was assessed by Visual Analogue Scale. The considered 30-day post-operative complications were atelectasis, need of endoscopic broncho-aspiration, pneumonia and pleural effusion. A total of 367 consecutive patients underwent thoracotomy in the study period. The median age was 68 (interquartile range 60-75) years. Rib fracture was detected in 179/367 (48.8%) patients. Incidence did not significantly vary throughout years (p = 0.98). The risk of developing post-thoracotomy rib fractures was significantly associated with age greater than the median value (p = 0.003). The presence of rib fracture was related to significantly more elevated evoked pain at 48 h after surgery (p = 0.039) and a higher incidence of complications (32/179 vs 20/188; p = 0.047). Our study demonstrated that rib fracture occurs in almost half of the thoracotomies. Older patients are more likely to develop this event, which significantly correlates to increased evoked post-operative pain and higher rate of post-operative complications.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

    求助全文

  • 文章类型: Journal Article
    目的:确定以人群为基础的肋骨骨折住院发生率和结果的长期趋势。
    方法:这是2015年至2022年在新南威尔士州确定的肋骨骨折病例的数据链接研究,澳大利亚。常规收集的健康数据与ED、入院患者和死亡登记数据收集。主要结果是肋骨骨折住院病例的年龄特异性发生率和风险调整后的30天死亡率。其他感兴趣的结果是住院时间(LOS),入院率和ICU入院率。
    结果:共分析70609例。总的来说,在2015年至2022年间,肋骨骨折住院人数增加了25%.病例比例最高的是45-65岁(28%)和65-85岁(31%)年龄组。按人口计算,发病率每年增加2%。在调整了年龄之后,合并症和损伤严重程度,在2015年至2022年期间,30日死亡率没有显著趋势.住院LOS中位数为4天,38%的患者停留1-2天。区域和农村地区的胸部受伤更严重。
    结论:肋骨骨折住院人数增加,老年患者推动了这一趋势。
    OBJECTIVE: Determine long-term trends in population-based incidence and outcomes of rib fracture hospitalisations.
    METHODS: This was a data linkage study of rib fracture cases identified between 2015 and 2022 in New South Wales, Australia. Routinely collected health data were linked between ED, admitted patient and death registry data collection. The primary outcomes were age-specific incidence of rib fracture hospitalisation cases and risk-adjusted 30 days mortality. Other outcomes of interest were hospital length of stay (LOS), admission rate and ICU admissions.
    RESULTS: A total of 70 609 cases were analysed. Overall, the number of rib fracture hospitalisations increased by 25% between 2015 and 2022. The highest proportion of cases was in the 45-65 years (28%) and 65-85 years (31%) age groups. On a per population basis, the incidence rate increased by 2% per annum. After adjusting for age, comorbidity and injury severity, there was no significant trend in 30 days mortality observed between 2015 and 2022. The median inpatient LOS was 4 days with 38% of patients staying 1-2 days. Regional and rural areas were associated with more severe chest injuries.
    CONCLUSIONS: Rib fracture hospitalisations have increased with older patients driving this trend.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

    求助全文

  • 文章类型: Journal Article
    目的:肋骨骨折后可发生肋间神经损伤,导致腹部肌肉组织的神经支配。腹直肌和肋间肌的神经支配丧失可引起疼痛,萎缩,以及最终的驱逐,这可能是肋骨骨折的一个未得到充分认识和治疗的并发症。我们调查了肋骨骨折后肋间神经电诊断测试的临床实用性,以诊断和定位T7及以下水平的神经损伤。
    方法:5例移位的涉及第7-11根肋骨和同侧腹壁临床扩张的双皮质肋骨骨折患者在患侧接受了肋间神经传导研究(NCS)和针肌电图(EMG)。在超声引导下进行腹直肌和肋间肌的肌电图,和超声测量腹直肌厚度来评估萎缩。
    结果:患者平均年龄为59.4岁,平均体重指数(BMI)为31.5kg/m2。肋间NCS和EMG能够可靠地诊断和定位肋骨骨折后的肋间神经损伤。超声显示患侧腹直肌横截面平均厚度为0.534cm,与未受影响一侧的1.024厘米相比。
    结论:肋间电诊断研究可以诊断和定位移位肋骨骨折后的肋间神经损伤。肌肉骨骼超声可用于诊断和量化腹直肌萎缩,并准确,安全地将针EMG引导到肋间肌和腹直肌。
    OBJECTIVE: Intercostal nerve injury can occur after rib fractures, resulting in denervation of the abdominal musculature. Loss of innervation to the rectus abdominis and intercostal muscles can cause pain, atrophy, and eventual eventration, which may be an underrecognized and thus undertreated complication of rib fractures. We investigated the clinical utility of intercostal nerve electrodiagnostic testing following rib fractures to diagnose and localize nerve injury at levels T7 and below.
    METHODS: Five patients with displaced bicortical rib fractures involving the 7th-11th ribs and clinical eventration of the ipsilateral abdominal wall underwent intercostal nerve conduction studies (NCS) and needle electromyography (EMG) on the affected side. EMG of the rectus abdominis and intercostal muscles was performed with ultrasound guidance, and ultrasound measurements of rectus abdominis thickness were obtained to assess for atrophy.
    RESULTS: Average patient age was 59.4 years and average body mass index (BMI) was 31.5 kg/m2. Intercostal NCS and EMG were able to reliably diagnose and localize intercostal nerve damage after rib fractures. Ultrasound demonstrated an average rectus abdominis transverse cross-sectional thickness of 0.534 cm on the affected side, compared with 1.024 cm on the non-affected side.
    CONCLUSIONS: Intercostal electrodiagnostic studies can diagnose and localize intercostal nerve damage after displaced rib fractures. Musculoskeletal ultrasound can be used to diagnose and quantify rectus abdominis atrophy and to accurately and safely guide needle EMG to the intercostal and rectus abdominis muscles.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

    求助全文

  • 文章类型: Journal Article
    背景:肋骨骨折(SSRF)的手术稳定越来越多,然而,在伤前抗血栓治疗期间接受SSRF治疗的患者的结局仍然未知.我们比较了接受和未接受抗血栓治疗的患者的手术变量和结果。我们假设损伤前抗凝治疗与SSRF延迟和不良预后相关。
    方法:对于这项回顾性队列研究,我们查询了胸部损伤国际数据库,2018年8月至2022年3月期间接受SSRF的患者。抗血栓治疗分为抗血小板和抗凝治疗。主要结果是从入院到SSRF的时间。次要结果包括SSRF持续时间和并发症。数值数据以中位数(IQR)表示,分类数据为数字(%)。使用逆概率加权来控制混杂。
    结果:纳入了118名SSRF患者,25例(11%)接受抗血栓治疗。这些患者年龄较大(72岁,(65-80岁)与57岁,(43-66);p<0.001),ISS较低(14,(10-20)对21,(14-30);p=0.002)。从入院到SSRF的时间相当(2天,(1-4)与2天,(1-4);p=0.37)手术时间(154分钟,(120.0-212.0)与177分钟相比,(143.0-210.0);p=0.34)。使用抗血栓药物的患者无ICU天数较少(24(22-26)对28(23-28);p=0.003),但无呼吸机天数较多(28,(28-28)对27(27-28);p<0.008)。在调整混杂因素后,伤前抗凝与延迟SSRF(相对风险,RR=1.37,95%CI0.30-6.24),手术时间(RR=1.07,95%CI0.88-1.31),IFD<=28(RR=2.05,95CI:0.33-12.67),VFD<=27(RR=0.71,95CI:0.15-3.48)或并发症(RR=0.55,95%CI0.06-5.01)。
    结论:在需要SSRF的患者中,伤前抗栓药物的使用既不会延迟SSRF,也不会影响手术时间,也不会增加并发症的风险。我们的数据表明,在伤前使用抗凝药的患者中,可以安全地进行SSRF。
    方法:IV.
    方法:治疗/护理管理。
    BACKGROUND: Surgical stabilization of rib fractures (SSRF) is increasingly performed, however the outcome of patients undergoing SSRF while on pre-injury antithrombotic therapy remains unknown. We compared surgical variables and outcomes of patients who were and were not on antithrombotic therapy. We hypothesize pre-injury anticoagulation is associated with delay in SSRF and worse outcomes.
    METHODS: For this retrospective cohort study, we queried the Chest Injury International Database, for patients undergoing SSRF between 08/2018 and 03/2022. Antithrombotic therapy was categorized into antiplatelet and anticoagulant use. Primary outcome was time from admission to SSRF. Secondary outcomes included SSRF duration and complications. Numerical data were presented as median (IQR), categorical data as number (%). Inverse probability weighting was used to control for confounding.
    RESULTS: Two hundred and eighteen SSRF patients were included, 25 (11 %) were on antithrombotic therapy. These patients were older (72 years, (65-80) versus 57 years, (43-66); p < 0.001) with lower ISS (14, (10-20) versus 21, (14-30); p = 0.002). Time from admission to SSRF was comparable (2 days, (1-4) versus 2 days, (1-4); p = 0.37) as was operative time (154 mins, (120.0-212.0) versus 177 mins, (143.0-210.0); p = 0.34). Patients using antithrombotics had fewer ICU-free days (24 (22-26) versus 28 (23-28); p = 0.003) but more ventilator free days (28, (28-28) versus 27 (27-28); p < 0.008). After adjusting for confounding, pre-injury anticoagulation was not significantly associated with delayed SSRF (Relative Risk, RR=1.37, 95 % CI 0.30-6.24), operative time (RR=1.07, 95 % CI0.88-1.31), IFD <=28 (RR=2.05, 95 %CI:0.33-12.67), VFD<=27 (RR=0.71, 95 %CI:0.15-3.48) or complications (RR=0.55, 95 % CI0.06-5.01).
    CONCLUSIONS: Pre-injury antithrombotic drug use neither delayed SSRF nor impacted operative time in patients requiring SSRF and was not associated with increased risk of complications. Our data suggest SSRF can be safely performed without delay in patients who use anticoagulation pre-injury.
    METHODS: IV.
    METHODS: Therapeutic/care management.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

    求助全文

公众号