Abstract：
Although stereotactic body radiotherapy (SBRT) is a curative treatment option for stage I non-small cell lung cancer (NSCLC), limited data are available regarding chest wall (CW) toxicities during an extended follow-up of over 10 years. We report an unusual case of a bone tumor-like CW mass lesion with pathological rib fractures observed 13 years after SBRT for peripheral lung cancer. Despite the initial suspicion of radiation-induced sarcoma, a subsequent incisional biopsy revealed no evidence of malignancy, and a definitive diagnosis of osteonecrosis was made. Thus, long-term observation of over 10 years is required to identify late chronic complications following SBRT.
摘要：
尽管立体定向放射治疗（SBRT）是I期非小细胞肺癌（NSCLC）的治愈性治疗选择，在超过10年的延长随访期间,关于胸壁(CW)毒性的数据有限.我们报告了在SBRT治疗周围型肺癌13年后观察到的骨肿瘤样CW肿块病变伴病理性肋骨骨折的不寻常病例。尽管最初怀疑是辐射诱导的肉瘤，随后的切开活检显示没有恶性肿瘤的迹象，并明确诊断为骨坏死。因此，需要超过10年的长期观察,以确定SBRT后的晚期慢性并发症.
