This study examined the effect of acute acetaminophen (ACTP) ingestion on physical performance during the 5 m shuttle run test (5mSRT), attention, mood states, and the perception of perceived exertion (RPE), pain (PP), recovery (PRS), and delayed onset of muscle soreness (DOMS) in well-trained female athletes. In a randomized, placebo-controlled, double-blind, crossover trial, fifteen well-trained female athletes (age 21 ± 2 years, height 165 ± 6 cm, body mass 62 ± 5 kg) swallowed either 1.5 g of ACTP or 1.5 g of placebo. The profile of mood states (POMS) and digit cancellation (DCT) were assessed 45 min postingestion, and 5mSRT was performed 60 min postingestion. The RPE and PP were determined immediately after each 30-s repetition of the 5mSRT, and the PRS and DOMS were recorded at 5 min and 24 h post-5mSRT. For the 5mSRT, ACTP ingestion improved the greatest distance (+ 10.88%, p < 0.001), total distance (+ 11.33%, p = 0.0007) and fatigue index (+ 21.43%, p = 0.0003) compared to PLA. Likewise, the DCT score was better on the ACTP (p = 0.0007) than on the PLA. RPE, PP, PRS, and DOMS scores were improved after ACTP ingestion (p < 0.01 for all comparisons) compared to PLA. POMS scores were enhanced with ACTP ingestion compared to PLA (p < 0.01). In conclusion, this study indicates that acute acetaminophen ingestion can improve repeated high intensity short-term maximal performance, attention, mood states, and perceptions of exertion, pain, recovery, and muscle soreness in well-trained female athletes, suggesting potential benefits for their overall athletic performance and mood state.

UNASSIGNED: This investigation aims to elucidate the impact of Ramadan intermittent fasting on performance, physiological responses, and bioenergetic pathway contributions during repeated sprints.
UNASSIGNED: Fourteen active male Muslim athletes (age = 22.4 ± 1.8 years, body weight = 69.5 ± 3.8 kg, height = 176 ± 5.1 cm) executed a repeated sprint protocol, consisting of ten 20-meter sprints with 15-s passive recovery intervals, during both fasting and non-fasting conditions. The fasting session was conducted after a 12-14 h fast following Sahur (the pre-dawn meal during Ramadan). In contrast, the non-fasting session occurred before the Ramadan fasting period began, during the same hours of the day, at a time when fasting was not yet required for the athletes. Bioenergetic pathway contributions during repeated sprints were quantified using the PCr-LA-O2 method.
UNASSIGNED: The mean sprint time during fasting sessions was 3.4 ± 0.3 s compared to 3.3 ± 0.2 s in non-fasting sessions, indicating a trend approaching the threshold of significance for slower times in the fasted state (p = 0.052, effect size (ES) = 0.34). In terms of bioenergetic contributions, the total metabolic energy expenditure (TEE) was slightly lower during fasting sessions (236.5 ± 22 kJ) compared to non-fasting sessions (245.2 ± 21.7 kJ), but this difference was not statistically significant (p = 0.102, ES = 0.40). Similarly, metabolic energy expenditure per sprint was 23.7 ± 2.2 kJ in fasting conditions compared to 24.5 ± 2.2 kJ in non-fasting conditions (p = 0.106, ES = 0.35). The oxidative energy contribution did not differ significantly between fasting (34.2 ± 4.1 kJ) and non-fasting conditions (34.2 ± 4.1 vs. 35.5 ± 5.2 kJ; p = 0.238, ES = 0.28). Similarly, lactic (60.4 ± 7.6 vs. 59.2 ± 8.3 kJ; p = 0.484, ES = 0.15); and alactic (149.3 ± 19.9 vs. 143 ± 21.5 kJ; p = 0.137, ES = 0.30) energy contributions showed no significant differences between the fasting and non-fasting sessions. The percentage of performance decrement (Pdec) and the percentage contributions of oxidative, lactic, and alactic pathways to the total energy expenditure did not differ significantly between the fasting and non-fasting conditions, indicating a similar bioenergetic profile across both conditions.
UNASSIGNED: The present findings indicate no significant differences in performance metrics and metabolic outcomes between fasted and non-fasted states. Future assessments with longer duration and higher intensity protocols may provide further insights.

This study aimed to compare the effects of an 8-week short-term training program, comprising repeated sprints or running-based high-intensity intermittent training (HIIT), on the aerobic fitness and repeated sprint ability (RSA) performance of sub-elite basketball referees. Twenty male referees participated in supervised training sessions twice a week. They were randomly assigned to either the RSA-based group (RSAG) or the running-based HIIT group (HIITG). The RSAG conducted 3-4 sets of 8 × 20-m all-out sprints, while the HIITG performed 2-3 sets of 6 × 20-s runs at 90% of their maximal velocity achieved in the 30-15 intermittent fitness test (30-15IFT). Referees underwent a graded exercise test on a treadmill, the 30-15IFT, and an RSA test before and after the training program. Both groups showed significant improvement (~3%) in the fastest (22.6 ± 1.4 vs. 23.4 ± 1.7 and 22.0 ±1.9 vs. 22.4 ± 1.7 km·h-1 in RSAG and HIITG, respectively) and mean (21.5 ± 1.2 vs. 22.4 ± 1.4 and 21.3 ± 1.8 vs. 21.7 ± 1.6 km·h-1 in RSAG and HIITG, respectively) sprint velocity of the RSA test (p < 0.05). Moreover, positive changes (p < 0.05) were observed in the 30-15IFT maximal velocity (18.6 ± 1.1 vs. 19.3 ± 1.0 and 19.4 ± 0.9 vs. 20.5 ± 0.9 km·h-1 in RSAG and HIITG, respectively). In conclusion, an 8-week training intervention using either RSA or running-based HIIT led to similar improvements in referees\' RSA performance and specific aerobic fitness measures. These findings could assist in devising tailored training programs for basketball referees.

Females demonstrate greater fatigue resistance during a range of exercise modalities; however, this may be confounded by the lower mechanical work completed. Accordingly, this study examined the sex-specific peripheral and central fatigue mechanisms during repeated all-out cycling and whether they are affected by total mechanical work performed. A total of 26 healthy young adults (12 females) performed 10 × 10 s all-out cycling interspersed by 30 s passive recovery. Metabolic responses, peripheral and central fatigue, were quantified via changes in pre- to post-exercise blood lactate, potentiated quadriceps twitch force (and contractile properties) evoked via supramaximal electrical stimulation of the femoral nerve, and voluntary activation of the knee extensors, respectively. During exercise, mechanical work, vastus lateralis muscle activation (via surface electromyography), and deoxygenation (via near-infrared spectroscopy) were recorded. Sex comparison analyses were performed before and after statistically controlling for total mechanical work (via ANCOVA). Mechanical work and muscle activation plateaued at similar sprint repetition (sprint 5) and voluntary activation change (pre vs. post) was similar between the sexes. Females, however, showed lower %work decrement (i.e., fatigability; P = 0.037) and peripheral responses as evident by lower reductions in quadriceps twitch force (P < 0.001) and muscle deoxygenation (P = 0.001). Adjusting for total mechanical work did not change these sex comparison results. We show that females\' greater fatigue resistance during repeated all-out cycling may not be attributed to the greater total mechanical work performed but could be mediated by lower peripheral fatigue in the knee extensor muscles.

UNASSIGNED: An imbalance of vastus medialis (VM) and vastus lateralis (VL) muscle activation and patterns of dyscoordination may contribute to the sex discrepancy in the incidence of patellofemoral pain syndrome (PFPS). While some studies have examined sex-specific VM/VL coordination strategies in some tasks, no previous studies have examined sex-specific VM/VL coordination strategies during repeated sprint exercise (RSE).
UNASSIGNED: In this study, asymptomatic young adults (N = 39, 19 females) completed a RSE protocol consisting of 10 × 10 s all-out cycling interspersed by 30 s of passive rest. Electromyographic (EMG) signals from the VM and VL muscles were recorded throughout exercise.
UNASSIGNED: VM:VL ratio did not change with fatigue and was not different between the sexes. From sprint 1 to 10, VM-VL onset delay increased from 9.62 to 16.95 ms and from 19.28 to 45.09 ms in males and females, respectively (p < 0.001); however, no sex difference was found (p = 0.524). Muscle activation amplitude plateaued at different sprint repetitions in males and females while mechanical work plateaued at similar repetitions.
UNASSIGNED: These findings suggest that sex differences in the incidence of PFPS may not be influenced by VM/VL muscle coordination as assessed by EMG.

OBJECTIVE: This study investigated the effects of both an active warm-up and the time-of-day variation on repeated-sprint performance. A second objective was to compare the post-exercise recovery between the experimental conditions.
METHODS: Eleven male participants performed ten maximal cycling sprints (6 s each, with a 30-s interval between them) in the morning and late afternoon, either after a warm-up or control condition. The warm-up consisted of cycling for 10 min at 50% of the peak aerobic power.
RESULTS: Rest measurements of rectal, muscle, and skin temperatures were higher in the afternoon compared to the morning (p < 0.05), with no significant differences in heart rate (p = 0.079) and blood lactate concentration (p = 0.300). Warm-up increased muscle temperature, heart rate, and lactate, and reduced skin temperature (all p < 0.001), though no significant differences were observed for rectal temperature (p = 0.410). The number of revolutions (p = 0.034, ηp2 = 0.375), peak (p = 0.034, ηp2 = 0.375), and mean (p = 0.037, ηp2 = 0.365) power of the first sprint (not the average of ten sprints) were higher in the afternoon compared to the morning, regardless of warm-up. However, beneficial performance effects of warming up were evident for the first (p < 0.001) and the average of ten sprints (p < 0.05), regardless of time of day. More remarkable changes during the 60-min post-exercise were observed for rectal temperature (p = 0.005) and heart rate (p = 0.010) in the afternoon than in the morning.
CONCLUSIONS: Warming-up and time-of-day effects in enhancing muscular power are independent. Although warm-up ensured further beneficial effects on performance than the time-of-day variation, a faster post-exercise recovery was observed in the late afternoon.

The aim of the present study was to examine the effects of creatine (Cr) supplementation on power output during repeated sprints on a non-motorized treadmill. Sixteen recreationally active males volunteered for this study (age 25.5 ± 4.8 y, height 179 ± 5 cm, body mass 74.8 ± 6.8 kg). All participants received placebo supplementation (75 mg of glucose·kg-1·day-1) for 5 days and then performed a baseline repeated sprints test (6 × 10 s sprints on a non-motorised treadmill). Thereafter, they were randomly assigned into a Cr (75 mg of Cr monohydrate·kg-1·day-1) or placebo supplementation, as above, and the repeated sprints test was repeated. After Cr supplementation, body mass was increased by 0.99 ± 0.83 kg (p = 0.007), peak power output and peak running speed remained unchanged throughout the test in both groups, while the mean power output and mean running speed during the last 5 s of the sprints increased by 4.5% (p = 0.005) and 4.2% to 7.0%, respectively, during the last three sprints (p = 0.005 to 0.001). The reduction in speed within each sprint was also blunted by 16.2% (p = 0.003) following Cr supplementation. Plasma ammonia decreased by 20.1% (p = 0.037) after Cr supplementation, despite the increase in performance. VO2 and blood lactate during the repeated sprints test remained unchanged after supplementation, suggesting no alteration of aerobic or glycolytic contribution to adenosine triphosphate production. In conclusion, Cr supplementation improved the mean power and speed in the second half of a repeated sprint running protocol, despite the increased body mass. This improvement was due to the higher power output and running speed in the last 5 s of each 10 s sprint.

In a sprint cross-country (XC) ski competition, the difference in recovery times separating the first and the second semi-final (SF) heats from the final (F) may affect performance. The aim of the current study was to compare the effects of longer vs. shorter recovery periods prescribed between the 3 knock-out races of a simulated sprint XC ski competition involving a prologue (P), quarter-final (QF), SF, and F.
Eleven well-trained XC ski athletes completed 2 simulated sprint XC ski competitions on a treadmill involving 4 × 883-m roller-ski bouts at a 4° incline using the gear 3 ski-skating sub-technique. The first 3 bouts were completed at a fixed speed (PFIX, QFFIX, and SFFIX) corresponding to ∼96% of each individual\'s previously determined maximal effort. The final bout was performed as a self-paced sprint time trial (FSTT). Test conditions differed by the time durations prescribed between the QFFIX, SFFIX, and FSTT, which simulated real-world XC ski competition conditions using maximum (MAX-REC) or minimum (MIN-REC) recovery periods.
The FSTT was completed 5.4 ± 5.5 s faster (p = 0.009) during MAX-REC (179.2 ± 18.1 s) compared to MIN-REC (184.6 ± 20.0 s), and this was linked to a significantly higher power output (p = 0.010) and total metabolic rate (p = 0.009). The pre FSTT blood lactate (BLa) concentration was significantly lower during MAX-REC compared to MIN-REC (2.5 ± 0.8 mmol/L vs. 3.6 ± 1.6 mmol/L, respectively; p = 0.027), and the pre-to-post FSTT increase in BLa was greater (8.8 ± 2.1 mmol/L vs. 7.1 ± 2.3 mmol/L, respectively; p = 0.024). No other differences for MAX-REC vs. MIN-REC reached significance (p > 0.05).
Performance in a group of well-trained XC skiers is negatively affected when recovery times between sprint heats are minimized which, in competition conditions, would occur when selecting the last QF heat. This result is combined with a higher pre-race BLa concentration and a reduced rise in BLa concentration under shorter recovery conditions. These findings may help inform decision making when XC skiers are faced with selecting a QF heat within a sprint competition.

Background: Modern coaches experience a drastic reduction of the available training time with an increasingly large number of competitions during the competitive season. Thus, they must choose wisely the most efficient methods to improve the physical fitness of their players during the preseason. Among all the methods, this study compared the effects of plyometric training (PT), sprint interval training (SIT), and small-sided games (SSGs) on the performance of recreationally trained soccer players. Methods: Seventy-three participants were randomly assigned in one of the three experimental groups (i.e., PT [n = 23], SIT [n = 26] or SSGs [n = 24]) and completed two sessions per week for a total of 3 weeks. Meanwhile, the whole group maintained their habitual soccer-specific training program who do not interfere in the preparation of the season. Repeated sprint ability (RSA), maximal aerobic speed (MAS), and a 30-m sprint were assessed at baseline (PRE) and post-training (POST). Results: Performance in SSGs decreased for the average speed from 0 to 10 m (V 0-10m; -0.84 km h-1, -4 ± 5%, p < 0.001), the maximal distance (D max) covered in the 30-s RSA test (-3.65 m, -3 ± 6%, p < 0.01) and MAS (-0.52 km h-1, -3 ± 6%, p < 0.01). PT increased the mean distance (D mean) covered in the 30-s RSA test (+5.98 m, 5 ± 4%, p < 0.001) and MAS (+0.58 km h-1, 7 ± 5%, p < 0.01) while an improvement of all parameters but the maximal sprint speed reached during the 30-m trip (V max) was found in the SIT group (V 0-10m: +1.462 km h-1, 8 ± 5%, p < 0.001; D max: +7.89 m, 6 ± 5%, p < 0.001; D mean: +8.69 m, 7 ± 5%, p < 0.001 and MAS: +1.74 km h-1, 12 ± 8%, p < 0.001). All SSG POST values were significantly lower than PT and SIT (p < 0.01). D mean and MAS in POST were also significantly higher in SIT than in the PT group (p < 0.001). Conclusion: This study suggests that both PT and SIT could be a better alternative to SSGs to boost performances during preseason. Moreover, SIT seems to produce higher improvements in physical performances than PT.

BACKGROUND: Compared with normoxia, repeated short (5-10 s) sprints (>10 efforts) with incomplete recovery (≤30 s) in hypoxia likely cause substantial performance reduction accompanied by larger metabolic disturbances and magnitude of neuromuscular fatigue. However, the effects of hypoxia on performance of repeated long (30 s) \"all-out\" efforts with near complete recovery (4.5 min) and resulting metabolic and neuromuscular adjustments remain unclear.
OBJECTIVE: The intention was to compare acute performance, metabolic, and neuromuscular responses across repeated Wingates between hypoxia and normoxia.
METHODS: On separate visits, 6 male participants performed 4 × 30-second Wingate efforts with 4.5-minute recovery in either hypoxia (fraction of inspired oxygen: 0.145) or normoxia. Responses to exercise (muscle and arterial oxygenation trends, heart rate, and blood lactate concentration) and the integrity of neuromuscular function in the knee extensors were assessed for each exercise bout.
RESULTS: Mean (P = .80) and peak (P = .92) power outputs, muscle oxygenation (P = .88), blood lactate concentration (P = .72), and perceptual responses (all Ps > .05) were not different between conditions. Arterial oxygen saturation was significantly lower, and heart rate higher, in hypoxia versus normoxia (P < .001). Maximal voluntary contraction force and peripheral fatigue indices (peak twitch force and doublets at low and high frequencies) decreased across efforts (all Ps < .001) irrespective of conditions (all Ps > .05).
CONCLUSIONS: Despite heightened arterial hypoxemia and cardiovascular solicitation, hypoxic exposure during 4 repeated 30-second Wingate efforts had no effect on performance and accompanying metabolic and neuromuscular adjustments.