Abstract：
This study examined the effect of acute acetaminophen (ACTP) ingestion on physical performance during the 5 m shuttle run test (5mSRT), attention, mood states, and the perception of perceived exertion (RPE), pain (PP), recovery (PRS), and delayed onset of muscle soreness (DOMS) in well-trained female athletes. In a randomized, placebo-controlled, double-blind, crossover trial, fifteen well-trained female athletes (age 21 ± 2 years, height 165 ± 6 cm, body mass 62 ± 5 kg) swallowed either 1.5 g of ACTP or 1.5 g of placebo. The profile of mood states (POMS) and digit cancellation (DCT) were assessed 45 min postingestion, and 5mSRT was performed 60 min postingestion. The RPE and PP were determined immediately after each 30-s repetition of the 5mSRT, and the PRS and DOMS were recorded at 5 min and 24 h post-5mSRT. For the 5mSRT, ACTP ingestion improved the greatest distance (+ 10.88%, p < 0.001), total distance (+ 11.33%, p = 0.0007) and fatigue index (+ 21.43%, p = 0.0003) compared to PLA. Likewise, the DCT score was better on the ACTP (p = 0.0007) than on the PLA. RPE, PP, PRS, and DOMS scores were improved after ACTP ingestion (p < 0.01 for all comparisons) compared to PLA. POMS scores were enhanced with ACTP ingestion compared to PLA (p < 0.01). In conclusion, this study indicates that acute acetaminophen ingestion can improve repeated high intensity short-term maximal performance, attention, mood states, and perceptions of exertion, pain, recovery, and muscle soreness in well-trained female athletes, suggesting potential benefits for their overall athletic performance and mood state.
摘要：
这项研究检查了在5m穿梭试验（5mSRT）期间急性摄入对乙酰氨基酚（ACTP）对物理性能的影响，注意,情绪状态，和感知努力(RPE)的感知，疼痛（PP），恢复（PRS），以及训练有素的女运动员肌肉酸痛（DOMS）的延迟发作。在一个随机的，安慰剂对照,双盲,交叉试验，15名训练有素的女运动员（年龄21±2岁，高度165±6厘米，体重62±5kg）吞下1.5gACTP或1.5g安慰剂。摄后45分钟评估情绪状态（POMS）和数字消除（DCT）的概况，5mSRT在摄食后60分钟进行。在每30秒重复5mSRT后立即测定RPE和PP，在5mSRT后5分钟和24小时记录PRS和DOMS。对于5mSRT，ACTP摄入改善了最大距离(+10.88%，p<0.001)，总距离(+11.33%，p=0.0007）和疲劳指数（+21.43%，p=0.0003)与PLA相比。同样，ACTP的DCT评分（p=0.0007）优于PLA。RPE,PP,PRS,与PLA相比，摄入ACTP后DOMS评分有所改善（所有比较p<0.01）。与PLA相比，摄入ACTP后POMS评分提高（p<0.01）。总之,这项研究表明，急性摄入对乙酰氨基酚可以改善重复高强度短期最大表现，注意,情绪状态，以及对努力的感知，疼痛,recovery,训练有素的女运动员肌肉酸痛，提示他们的整体运动表现和情绪状态的潜在好处。
