Precision control

  • 文章类型: Editorial
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  • 文章类型: Review
    Schistosomiasis is a parasitic disease that seriously endangers human health and affects socioeconomic developments. Artificial intelligence technology has been widely used in clinical medical sciences, including tumor screening, and electrocardiogram, imaging and pathological analyses, which has potential for precision control of schistosomiasis. Currently, artificial intelligence technology has been employed for clinical assessment of schistosomiasis-associated hepatic fibrosis and ectopic schistosomiasis, prognostic prediction of advanced schistosomiasis, automated identification of Oncomelania hupensis and Schistosoma japonicum eggs and miracidia, epidemiological surveillance of schistosomiasis, and drug discovery. This review summarizes the advances in the applications of artificial intelligence technology in the management of schistosomiasis and proposes the prospects for the use of artificial intelligence in schistosomiasis elimination.
    [摘要] 血吸虫病是一种严重危害人类健康、影响社会经济发展的寄生虫病。人工智能技术巳广泛应用于肿瘤筛查、心电图、影像学与病理学分析等临床医学领域,并有望实现血吸虫病精准防控。目前,人工智能技术巳应用于血吸虫病肝纤维化、异位血吸虫病临床评估, 晚期血吸虫病预后预测, 钉螺、虫卵、毛呦自动检测,血吸虫病流行病学监测和药物发现等方面。本文对近年来人工智能技术在血吸虫病防控领域的应用进展与前景进行综述。.
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  • 文章类型: Journal Article
    浸涂机提供可用于在基材上获得均匀且一致的涂层的紧凑装置。本文介绍了一种成本较低的浸涂机设计,其规格与其他浸涂机相似。该机由NEMA23步进电机,触摸屏显示,和丙烯酸外壳,以保护基材免受灰尘。机器使用ArduinoIDE编程,允许进行简单的更改。浸涂机的小尺寸使其非常适合在实验室中使用。大多数组件在购买后不需要更改,允许容易的更换和施工。
    Dip coaters provide a compact device that can be used to obtain uniform and consistent coatings on a substrate. This article describes a less costly dip coater design with similar specifications to other dip coaters. The machine consists of a NEMA 23 stepper motor, touch screen display, and acrylic housing to protect the substrate from dust. The machine is programmed using Arduino IDE, allowing for easy changes to be made. The small size of the dip coater makes it ideal for use in labs. The majority of the components require no alterations after purchase, allowing for easy replacements and construction.
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  • 文章类型: Journal Article
    Oncomelania hupensis is the only intermediate host of Schistosoma japonicum, and O. hupensis control is an important measure for schistosomiasis control. With the progress of national schistosomiasis control program, the prevalence of schistosomiasis is low in China; however, there are still multiple challenges for O. hupensis breeding and schistosomiasis transmission risk. Considering the target of the national schistosomiasis elimination program and environmental protection in the new era, the introduction of precision identification, precision interventions and precision assessment into O. hupensis control may facilitate the progress towards elimination of schistosomiasis in China.
    [摘要] 钉螺是日本血吸虫的唯一中间宿主, 钉螺控制是血吸虫 病防治的重要措施之一。随着防治进程推进, 我国血吸虫病呈低 水平流行状态, 但钉螺孳生和血吸虫病传播风险依然严峻。在新 时期血吸虫病防治目标和环境保护等要求下, 在钉螺控制中引入 精准识别、精准干预和精准评价, 巩固现有防治成效, 将有助于推 进我国消除血吸虫病进程。.
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  • 文章类型: Journal Article
    Currently, the national schistosomiasis control program of China is moving from transmission interruption to elimination, and there are multiple challenges during the stage moving towards the progression of schistosomiasis elimination, including a high difficulty in shrinking snail-infested areas, unstable achievements for infectious source control, imperfect surveillance system and a reduction in schistosomiasis control and administration. Based on the core suggestions proposed in the 2022 WHO guideline on control and elimination of human schistosomiasis, recommendations on schistosomiasis surveillance system building, development of novel diagnostics, adjustment of the schistosomiasis control strategy and maintaining and improvements of the schistosomiasis control capability are proposed for the national schistosomiasis control program of China in the new era according to the actual status of schistosomiasis control in China. Formulation of the national schistosomiasis control strategy and goal from One Health perspective, verification of transmission interruption and elimination of schistosomiasis, precision implementation of schistosomiasis control interventions with adaptations to local circumstances, development and application of highly sensitive and specific diagnostics are recommended for elimination of schistosomiasis in China. In addition, the implementation of the 2022 WHO guideline on control and elimination of human schistosomiasis may guide the elimination of schistosomiasis in China.
    [摘要] 目前, 我国血吸虫病防治工作正处于从传播阻断迈向消除的关键阶段, 同时也面临进一步压缩钉螺面积难度 大、传染源控制成果不牢固、监测体系不完善、防治管理有所松懈等诸多问题和挑战。本文依据《WHO 控制和消除人体 血吸虫病指南》核心建议, 结合我国血吸虫病防治工作实际, 对新时期我国血吸虫病监测体系建设、检测新技术研发、防 治策略调整、防治能力维持和提高等提出了相应建议。要从全健康角度谋划我国血吸虫病防治策略和目标; 要适时对血 吸虫病传播阻断和消除进程开展验证; 要在充分评估的基础上因时因地调整防治策略, 精准实施血吸虫病防治措施; 要 重视和加强高敏感度、高特异度检测工具的开发和应用, 为消除血吸虫病提供技术支撑; 要借鉴和吸收《WHO 控制和消 除人体血吸虫病指南》精髓, 充分发挥其引导作用, 促进我国实现消除血吸虫病目标。.
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  • 文章类型: Journal Article
    对森林资源的不断增长的需求正在推动对能够拯救和保护森林的更智能系统的需求,这些系统可以优化敏捷的林业生产。本研究使用木质中密度纤维板(MDF)的连续热压过程来研究连续平压过程自动质量控制的可能性。为此,基于元胞自动机(CA)理论,对机构和序列参数控制进行了概念数字孪生建模。构建了分布式协调模式框架,并提出了一种工艺控制编程方法,用于MDF连续平压的质量控制。基于中密度纤维板连续平压工艺机构和控制标准,定义了用于连续面板系统(CPS)的圆柱体阵列的五个分布式平板压力机协同控制模式元素的框架。为满足分布距离伺服和压力伺服对多级热压工艺设计的要求,利用模式元素构建了五种多机架组的协同协同协同控制模式:针对板坯生产中的四种典型偏差,即,厚度,斜坡,抑郁症,凸起,编制了多区域相互合作模式船舶控制序列。根据实时偏差的类型和强度,应用了相应的调控序列。这有效地抵消了实际生产中由于多场耦合效应而产生的不确定性干扰造成的偏差。应用测试表明,连续平压机的调整和响应时间都有了很大的改善,质量优良率控制在95%以上,从而证实了控制策略的有效性。
    The increasing demand for forestry resources is driving the need for smarter systems capable of saving and protecting forests that can optimize agile forestry production. This study uses the continuous hot-pressing process of wooden medium-density fiberboard (MDF) to investigate the possibility of automatic quality control of the continuous flat pressing process. For this purpose, conceptual digital twin modeling for mechanism and sequence parameter control was conducted based on the cellular automata (CA) theory. A distributed coordination mode framework was constructed, and a craft control programming method was proposed for the quality control of MDF continuous flat pressing. Based on the MDF continuous flat press craft mechanism and control standards, a framework of five distributed flat press cooperative control mode elements for the cylinder array of the continuous panel system (CPS) was defined. To satisfy the distributed distance servo and pressure servo demands of the multi-stage hot pressing craft design, five kinds of synergy collaborative control modes of multiple rack groups were constructed using mode elements: For the four types of typical deviations in slab production, i.e., thickness, slope, depression, and bulge, a multi-zone mutual cooperative mode craft control sequence was programmed. According to the type and intensity of real-time deviation, the corresponding regulation sequence was applied. This effectively counteracts the deviation caused by the uncertainty interference due to the multi-field coupling effect in actual production. The application tests demonstrate that the adjustment and response time of the continuous flat press were greatly improved, and the quality superiority rate is controlled above 95%, thereby confirming the effectiveness of the control strategy.
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  • 文章类型: Journal Article
    This paper reviews the evolution of the schistosomiasis control strategy in China at various stages after the founding of the People\'s Republic of China, and analyzes the roles and main problems of the schistosomiasis control strategy at different stages. At the end stage of schistosomiasis elimination, the integrated strategy with emphasis on infectious source control should be continued to be sustained and the problems regarding the implementation of this integrated strategy are analyzed. In addition, the countermeasures to solve these problems are proposed.
    [摘要] 本文回顾了新中国成立后不同时期我国血吸虫病防治策略的演变, 并对各时期血吸虫病防治策略的作用及其 存在的主要问题进行了分析。指出了在我国消除血吸虫病最后阶段应继续坚持以传染源控制为主的综合防治策略, 并 对这一策略实施过程中需要重点关注的问题进行了深入分析, 提出了有针对性的防控措施。.
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  • 文章类型: Journal Article
    In China, the mountainous and hilly schistosomiasis-endemic regions are mainly distributed in 2 provinces of Sichuan and Yunnan. Following the concerted efforts for more than 60 years, great successes have been achieved in schistosomiasis control in mountainous and hilly regions of China. Recently, Sichuan and Yunnan provinces seized the opportunity created in the rural and agriculture development, implemented the integrated strategy with emphasis on infectious source control, utilized modern information techniques, innovated schistosomiasis control models, built sensitive and highly effective surveillance-response systems, and actively tackled the challenges of schistosomiasis elimination, which greatly facilitated the progress towards elimination of schistosomiasis in mountainous and hilly regions of China.
    [摘要] 我国山丘型血吸虫病流行区主要分布于四川和云南 2 省。通过六十余年的积极防控, 山丘型流行区血吸虫病防治工作取得了显著成效。近年来, 四川、云南 2 省抓住农村农业发展新机遇, 积极落实以传染源控制为主的综合防治策略, 有效利用现代信息技术手段, 创新防治模式, 构建敏感、高效的监测体系, 积极应对消除进程中面临的诸多挑战, 有 力推动了我国山丘型流行区血吸虫病消除工作进程。.
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  • 文章类型: Journal Article
    The beneficial use of computer simulations to track the microstructural evolution of individual species is highlighted in view of macromolecular engineering and design, considering two case studies on catalytic polymerization, and both \"low\" (<100) and \"high\" (>100) chain lengths, that is, i) atom transfer radical copolymerization of n-butyl acrylate and styrene aiming at the synthesis of functional macrospecies of \"identical\' chain length; and ii) chain shuttling polymerization of ethylene and 1-octene toward the production of segmented block copolymers with \"soft\" and \"hard\" segments. Model parameters are validated and/or tuned based on literature data. The modeling strategy supports the future identification of chemical structure-polymer property relationships and is based on the combination of principles from polymer reaction engineering, chemistry, and physics.
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  • 文章类型: Journal Article
    The Second Forum on Schistosomiasis Control in China was successfully held in Jiangsu Institute of Parasitic Diseases during the period between 21th and 23th, September, 2017. Based on the topic \"Implementation of precision control to accelerate the progress towards schistosomiasis elimination\", the forum discussed three macro problems pertaining to how to improve the theory and policy of precision control during the progress towards schistosomiasis elimination in China, and six technical problems regarding how to achieve more precise management of the residual sources of infections and more precise monitoring of transmission risk. Finally, a consensus was achieved that precision control is essential to achieve the goal of schistosomiasis elimination in China.
    [摘要] 第二届中国血吸虫病防治论坛, 于2017年9月21-23日在江苏省血吸虫病防治研究所成功举行。论坛以“实施 精准防控, 加快消除进程”为主题, 围绕当前我国在血吸虫病消除进程中面临的如何进一步完善血吸虫病精准防控理论 和政策等三大宏观问题、如何实现针对残存传染源控制和传播风险监测的更精准化等六个技术难题展开了研讨, 达成了 “实施精准防控是实现我国消除血吸虫病目标的必由路径”的共识。.
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