小儿花粉食物过敏综合征(PFAS)的原因因特定地区的空气花粉水平而异。我们的目的是分析空气中的花粉计数,IgE致敏率,韩国和日本过敏儿童的PFAS发病率。
这项横断面研究包括2017年5-17岁过敏儿童。从韩国釜山收集了空气传播的花粉样本,日本的福冈和藤木。问卷调查用于评估支气管哮喘,季节性过敏性鼻炎,特应性皮炎,食物过敏,和PFAS。翼状尘螨特异性血清IgE,花粉,番茄,和桃子被调查了。
总共,来自釜山的57、56和20名患者,福冈,还有Tochigi,分别,已注册。福冈和藤木以机载日本雪松和柏树花粉为主,而釜山以松树和and木花粉为主。福冈和藤木过敏儿童对日本雪松的致敏率明显较高,柏树,Juniper,果园草,马蹄草,日本跳,和番茄与釜山的孩子相比。在福冈和藤木,日本雪松和柏树花粉经常散落在那里,在过敏儿童中观察到高敏化。致敏率不受Alder花粉计数的影响,草,马蹄草,日本人跳。在多变量分析中,仅Alder致敏与PFAS相关(比值比:6.62,95%置信区间:1.63-26.87,p=0.008).在釜山和Tochigi的PFAS患者中,与桦树过敏原Betv1相关的桃子是PFAS的致病食物。此外,在福冈,PFAS与the草和日本啤酒花花粉致敏有关。
不管花粉数如何,al花粉致敏与儿童PFAS相关。草和日本啤酒花花粉致敏与PFAS有关,特别是在日本南部的儿童中。
Causes of pediatric pollen food allergy syndrome (PFAS) differ depending on airborne pollen levels in a particular region. We aimed to analyze airborne pollen counts, IgE sensitization rates, and PFAS incidence among children with allergies in South Korea and Japan.
This cross-sectional study included children aged 5-17 years with allergies in 2017. Airborne pollen samples were collected from Busan in South Korea, and Fukuoka and Tochigi in Japan. Questionnaires were used to assess bronchial asthma, seasonal allergic rhinitis, atopic dermatitis, food allergy, and PFAS. The serum IgE specific to Dermatophagoides pteronyssinus, pollen, tomato, and peach were investigated.
In total, 57, 56, and 20 patients from Busan, Fukuoka, and Tochigi, respectively, were enrolled. Airborne Japanese cedar and cypress pollen were predominant in Fukuoka and Tochigi, whereas pine and alder pollen were predominant in Busan. Children with allergies in Fukuoka and Tochigi had a significantly higher sensitization rate to Japanese cedar, cypress, juniper, orchard grass, ragweed, Japanese hop, and tomato compared with children in Busan. In Fukuoka and Tochigi, where Japanese cedar and cypress pollen were frequently scattered, high sensitizations among allergic children were observed. The sensitization rate was not affected by the pollen count in alder, grass, ragweed, and Japanese hop. In multivariable analysis, only alder sensitization was found to be associated with PFAS (odds ratio: 6.62, 95% confidence interval: 1.63-26.87, p = 0.008). In patients with PFAS in Busan and Tochigi, peach associated with birch allergen Bet v 1 was a causative food item for PFAS. Moreover, PFAS was associated with ragweed and Japanese hop pollen sensitization in Fukuoka.
Regardless of pollen counts, alder pollen sensitization was associated with PFAS in children. Ragweed and Japanese hop pollen sensitization were associated with PFAS, particularly among children in southern Japan.