Mondiawhitei是一种原产于撒哈拉以南非洲的芳香植物。这种香料通常用于治疗各种疾病,比如高血压,糖尿病,勃起功能障碍,早泄.进行这项审查是为了提供有关植物学的最新信息,植物化学,药理学,和该植物的毒理学知识与非洲人口高度相关。此外,根据先前的实验研究描述了其作用机理。数据来自各种在线数据库,如PubMed,谷歌学者,Scopus,科学直接,WebofScience,施普林格链接,泰勒和弗朗西斯,SciFinder此外,书籍,书籍章节和程序被用作次要来源。使用PubChemSketcher程序绘制了植物化合物的化学结构。白术含有各种植物化合物,包括还原糖,三萜,类固醇,生物碱,皂苷,单宁,酚类物质,氰化氢,类胡萝卜素,草酸盐和植酸盐。此外,对-戊基苯基苯甲酸酯,(-)-洛利内酯,5-氯丙铂,propacin,2-羟基-4-甲氧基苯甲醛,异香草醛,9-hexacosene,2-己烯-1-醇,从此香料中分离出七氯烷。M.whitei有几个药理作用,包括壮阳药,亲肥沃,亲勃起,雄激素,抗氧化剂,抗寄生虫,抗疟药,抗菌,抗病毒,抗真菌药,抗癫痫药,抗炎,镇痛药,抗抑郁药,止泻药,保肝,抗镰刀菌,和抗癌活动。毒理学研究表明,口服治疗一周后,LD50高于5000mg/Kg,没有毒性迹象。这种香料的壮阳作用是其主要活动之一,在众多实验研究的支持下。因为WhiteiM.延迟了球海绵体肌肉的收缩,它的壮阳作用可以通过射精脊髓发生器的调节来介导。这可以证明其在治疗早泄中的民俗使用是合理的。
Mondia whitei is an aromatic plant native to sub-Saharan Africa. This spice is commonly used in the treatment of various diseases, such as hypertension, diabetes, erectile dysfunction, and premature ejaculation. This review was undertaken to provide updated information on the botanical, phytochemical, pharmacological, and toxicological knowledge of this plant of high relevance to African populations. Moreover, its mechanism of action was described based on previous experimental studies. Data were compiled from various online databases such as PubMed, Google Scholar, Scopus, Science Direct, Web of Science, Springer link, Taylor and Francis, and SciFinder. Additionally, books, book chapters and proceedings were used as secondary sources. The chemical structures of phytocompounds were drawn using PubChem Sketcher program. M. whitei contains various phytocompounds, including reducing sugars, triterpenes, steroids, alkaloids, saponins, tannins, phenolics, hydrogen cyanide, carotenoid, oxalate and phytate. Moreover, para-pentylphenyl-benzoate, (-)-Loliolide, 5-chloropropacin, propacin, 2-hydroxy-4-methoxybenzaldehyde, isovanillin, 9-hexacosene, 2-hexen-1-ol, and heptacosane were isolated from this spice. M. whitei has several pharmacological benefits, including aphrodisiac, pro-fertile, pro-erectile, androgenic, antioxidant, antiparasitic, antimalarial, antibacterial, antiviral, antifungal, antiepileptic, anti-inflammatory, analgesic, antidepressant, antidiarrheal, hepatoprotective, antisickling, and anticancer activities. Toxicological studies showed an LD50 of above 5000 mg/Kg and no signs of toxicity after one week of oral treatment. The aphrodisiac effect of this spice is one of its main activities, supported by numerous experimental studies. Because M. whitei delays contractions of the bulbospongiosus muscles, its aphrodisiac effect could be mediated through the modulation of the spinal generator of ejaculation. This can justify its folkloric use in the treatment of premature ejaculation.