目的:糖尿病患者心血管风险增加。对糖尿病患者的血糖和血脂控制知之甚少。我们旨在评估糖尿病患者心肌梗死时的血糖和血脂控制。
方法:所有已知的2型糖尿病患者在3月1日至12月31日期间在我们的冠心病监护病房连续入院,2021年被纳入这项回顾性研究。通过糖化血红蛋白(HbA1c)和低密度脂蛋白胆固醇(LDL-c)的个体化目标评估血糖和血脂控制,分别。入院时,通过药物和解获得了慢性药物的综合清单.
结果:本研究纳入112例患者,中位年龄72岁。大多数患者的HbA1c和LDL-c的个性化目标为7.0%(67%)和0.55g/L(96%),分别。HbA1c和LDL-c的未控制患者的比率为46%,90%,分别为42%。不受控制的患者中使用非最佳降糖药物和降脂药物的比例分别为63%和87%,分别。不适当的降糖和降脂药物的发生率为73%和91%,分别。
结论:我们强调了高风险CV患者的血糖和血脂控制不佳。迫切需要开发多学科方法来优化CV危险因素控制,以减少心肌梗塞和中风。
OBJECTIVE: Cardiovascular risk is increased in patients with diabetes. Little is known about glycemic and lipid control in patients with diabetes. We aimed to assess glycemic and lipid controls in patients with diabetes at time of their myocardial infarction.
METHODS: All known patients with type 2 diabetes consecutively admitted for a myocardial infarction in our coronary care unit between March 1st and December 31st, 2021 were included in this retrospective study. Glycemic and lipid control was assessed through individualized target of glycated haemoglobin (HbA1c) and low-density lipoprotein cholesterol (LDL-c), respectively. At admission, the comprehensive list of chronic medications was obtained through medication reconciliation.
RESULTS: This study included 112 patients with a median age of 72 years. Most of patients had an individualized target of HbA1c and LDL-c of 7.0% (67%) and 0.55g/L (96%), respectively. The rate of uncontrolled patients for HbA1c and LDL-c and both was 46%, 90%, and 42% respectively. The rate of patients with non-optimal glucose- and lipid-lowering medications in uncontrolled patients was 63% and 87%, respectively. The rate of inappropriate glucose- and lipid-lowering medications was 73% and 91%, respectively.
CONCLUSIONS: We highlighted the poor glycemic and lipid control in high-risk CV patients. There is an urgent need to develop multidisciplinary approaches to optimize CV risk factors control to reduce myocardial infarction and strokes.