■用于治疗腰椎神经根病的硬膜外注射可能与神经损伤和硬膜外脓肿等严重并发症有关。伤害性感受器具有伪单极的独特性质,因为它的两端预计功能相同。我们假设在远端给予周围神经阻滞应该能够缓解疼痛。这项前瞻性研究计划评估周围神经阻滞在腰椎神经根病中的疗效。
■34名符合资格标准的患者被纳入这项开放标记的前瞻性初步研究。他们在踝关节水平用4毫升0.25%布比卡因和40毫克曲安奈德进行周围神经阻滞。
■15天测量的结果,1个月,2个月,干预后3个月分别进行疼痛强度(数值评定量表),全球感知效应,功能状态(罗兰·莫里斯残疾问卷),贝克的抑郁量表得分,就业状况,和镇痛药的摄入量。
■在15天,1个月,两个月,88%的患者报告其疼痛评分降低≥50%,GPE≥6,而在3个月时,85%的患者报告其疼痛评分显着降低,GPE≥6。
■周围神经阻滞可有效治疗慢性腰骶部神经根病患者的疼痛。在门诊环境中管理它的能力,没有图像指导和没有使人衰弱的副作用,使它成为一个有吸引力的治疗选择。
UNASSIGNED: The epidural injections used to treat lumbar radiculopathy are potentially associated with serious complications like neurological injuries and epidural abscess. The nociceptors have the unique property of being pseudo-unipolar, as its both ends are expected to be functionally same. We have hypothesized that peripheral nerve blocks given at the distal site should be able to provide pain relief. This prospective study was planned to assess the efficacy of peripheral nerve blocks in lumbar radiculopathy.
UNASSIGNED: Thirty-four patients who fit the eligibility criteria were included in this open labeled prospective preliminary study. They were administered peripheral nerve blocks at ankle level with 4 ml of 0.25% bupivacaine and 40 mg of triamcinolone.
UNASSIGNED: The outcomes measured at 15 days, 1 month, 2 months, and 3 months after the intervention were the pain intensity (Numerical Rating Scale), the Global Perceived Effect, functional status (Roland Morris Disability Questionnaire), Beck\'s Depression Inventory score, employment status, and analgesic intake.
UNASSIGNED: At 15 days, 1 month, and 2 months, 88% of the patients reported a ≥50% decrease in their pain scores and a GPE ≥6, while at 3 months 85% of the patients reported a significant decrease in their pain scores and a GPE ≥6.
UNASSIGNED: Peripheral nerve blocks are effective in the management of pain in patients with chronic lumbosacral radiculopathy. The ability to administer it in an outpatient setting, without image guidance and the absence of debilitating side effects, makes it an attractive treatment option.