Abstract：
Patients with burns suffer from excruciating pain, thus presenting unique challenges to the hospital staff involved in their care. Any hospital system may be involved in managing smaller and less serious burns, but patients with more complicated issues are often transferred to a burn center. This article will review the pathophysiological evolution of pain immediately after burn injury to emphasize the role of complex inflammatory pathways involved in the progression of burn pain. This review also focuses on managing acute pain using a combined multimodal and regional pain management approach. Finally, we attempt to address the continuum from acute to chronic pain management and the strategies used to minimize and manage the progression to chronic pain. Chronic pain remains a debilitating outcome of burn injury, and this article discusses efforts to mitigate this complication. Available options for pain treatment are important to discuss, as current drug shortages may limit medications that can be used.
摘要：
烧伤患者遭受剧烈疼痛,因此，对参与护理的医院工作人员提出了独特的挑战。任何医院系统都可能参与管理较小和较不严重的烧伤，但是患有更复杂问题的患者通常会转移到烧伤中心。本文将回顾烧伤后即刻疼痛的病理生理学演变，以强调复杂的炎症途径在烧伤疼痛进展中的作用。这篇综述还着重于使用多模式和区域性疼痛管理方法联合管理急性疼痛。最后,我们试图解决从急性到慢性疼痛管理的连续性以及用于最小化和管理慢性疼痛进展的策略.慢性疼痛仍然是烧伤的一个令人衰弱的结果，本文讨论了减轻这种复杂性的努力。讨论疼痛治疗的可用选择很重要，因为目前的药物短缺可能会限制可以使用的药物。
