目的:这项纵向研究旨在检查感知控制的现状,自我管理效能感,接受放疗的乳腺癌患者的总体生活质量(QoL),了解放疗过程中影响患者生活质量的动态趋势和因素。
方法:参与者完成了癌症经历和疗效量表(CEES),人们用来促进健康的策略(SUPPH),和乳腺癌治疗功能评估(FACT-B)。数据采用SPSS26.0软件进行分析。重复测量方差分析(ANOVA)和混合效应线性模型被用来分析感知控制的趋势,自我管理效能感,和QoL在三个时间点,以及影响放疗期间QoL的因素。
结果:放疗过程中感知的控制和自我管理效能与QoL相关。自我管理效能感(β=0.30,P<0.001),化疗的存在(β=18.33,P=0.024),病程(β=2.25,P=0.028)对QoL的变化有积极影响,而时间(β=-2.95,P<0.001),癌症经历(β=-0.46,P<0.001),医疗保险类型(β=-2.77,P=0.021)对QoL的变化有负面影响。
结论:QoL,感知控制,乳腺癌患者放疗期间自我效能呈现动态变化。自我效能感越高,QoL越好,当疾病控制感差时,QoL越差。同时,病程较长的乳腺癌放疗患者的QoL,接受化疗,和不同的医疗支付方式。
OBJECTIVE: This longitudinal study aims to examine the present state of perceived control, self-management efficacy, and overall quality of life (QoL) in patients with breast cancer undergoing radiotherapy, and gain insight into the dynamic trends and factors that influence the quality of life experienced by patients during the course of radiotherapy.
METHODS: Participants completed the Cancer Experience and Efficacy Scale (CEES), Strategies Used by People to Promote Health (SUPPH), and Functional Assessment of Cancer Therapy- Breast (FACT-B). The data was analyzed using the software SPSS26.0. Repeated measures analysis of variance (ANOVA) and mixed-effects linear models were used to analyze trends in perceived control, self-management efficacy, and QoL at three-time points, as well as factors affecting QoL during radiotherapy.
RESULTS: Perceived control and self-management efficacy were associated with QoL over the course of the radiotherapy. Self-management efficacy (β = 0.30, P < 0.001), presence of chemotherapy (β = 18.33, P = 0.024), and duration of illness (β = 2.25, P = 0.028) had a positive effect on the change in QoL, while time (β = - 2.95, P < 0.001), cancer experience (β = - 0.46, P < 0.001), and type of medical insurance (β = - 2.77, P = 0.021) had the negative effect on the change in QoL.
CONCLUSIONS: The QoL, perceived control, and self-efficacy of patients with breast cancer show dynamic changes during radiotherapy. The higher the self-efficacy, the better the QoL, and the worse the QoL when the sense of disease control is poor. At the same time, more attention should be paid to the QoL of breast cancer radiotherapy patients with a long course of the disease, receiving chemotherapy, and different medical payment methods.