UNASSIGNED:这项研究评估了最大氧脉冲(O2Pmax)对慢性阻塞性肺疾病(COPD)患者的影响,并证实了对COPD急性加重(AECOPD)的预测作用。
UNASSIGNED:这项回顾性研究包括91名接受心肺运动试验(CPET)的参与者,肺功能测试,呼吸困难量表评估,和3年的随访。根据O2P最大值将参与者分为两组。锻炼能力,通气条件,气体交换效率,和呼吸困难症状进行了比较,并评估了O2Pmax与这些指标之间的相关性。检查了O2Pmax预测AECOPD的能力。
未经授权:运动能力,通气条件,气体交换效率较低,O2Pmax受损组呼吸困难症状评分较高(P<0.05)。O2Pmax与用力肺活量(FVC)%呈正相关,1秒用力呼气量(FEV1)%,FEV1/FVC%,无氧阈值(AT),工作率(WR)%,轴心摄氧量(VO2max)%,最大VºO2/kg,V²O2/kgmax%,WRAT,WR最大值,V♪O2AT,V♪O2max,和VäEmax,与EqCO2AT呈负相关,和EqCO2max(P<0.05)。最重要的是,O2P最大值可用于预测AECOPD,最佳临界值为89.5%(曲线下面积,0.739;95%CI,0.609-0.869)。
未经批准:O2P最大反映运动能力,通风能力,气体交换能力,COPD患者的呼吸困难症状可能是AECOPD的独立预测因子。
UNASSIGNED: This study evaluated the effect of maximal oxygen pulse (O 2P max) on patients with chronic obstructive pulmonary disease (COPD) and confirmed the predictive effect on acute exacerbations of COPD (AECOPD).
UNASSIGNED: This retrospective study included 91 participants who underwent cardiopulmonary exercise testing (CPET), lung function testing, a dyspnea scale assessment, and a 3-year follow-up. The participants were divided into two groups according to the O 2P max value. Exercise capacity, ventilatory conditions, gas exchange efficiency, and dyspnea symptoms were compared, and the correlations between O 2P max and these indices were evaluated. The ability of O 2P max to predict AECOPD was examined.
UNASSIGNED: Exercise capacity, ventilatory conditions, and gas exchange efficiency were lower, and dyspnea symptom scores were higher in the impaired O 2P max group ( P < 0.05). O 2P max was positively correlated with forced vital capacity (FVC)%, forced expiratory volume in 1 sec (FEV 1)%, FEV 1/FVC%, anaerobic threshold (AT), work rate (WR)%, aximal oxygen uptake (V̇O 2max)%, V̇O 2/kg max, V̇O 2/kg max%, WR AT, WR max, V̇O 2AT, V̇O 2max, and V̇ Emax, and was negatively correlated with EqCO 2AT, and EqCO 2max ( P < 0.05). Most importantly, O 2P max could be used to predict AECOPD, and the best cut-off value was 89.5% (area under the curve, 0.739; 95% CI, 0.609-0.869).
UNASSIGNED: O 2P max reflected exercise capacity, ventilation capacity, gas exchange capacity, and dyspnea symptoms in patients with COPD and may be an independent predictor of AECOPD.