Orbital fracture

眼眶骨折
  • 文章类型: Journal Article
    引言创伤性面部损伤,导致面部骨折是创伤事件的重要子集,随着年龄成为影响其病因和结局的关键决定因素。了解创伤性面部骨折的年龄相关模式对于制定有针对性的预防和管理策略至关重要。在这种情况下,阿巴拉契亚三州地区是一个关于这个问题的未充分开发的地区,需要进行全面的研究,以阐明在这种地理背景下与年龄相关的创伤性面部骨折的细微差别。方法这项回顾性研究探讨阿巴拉契亚三州地区创伤性面部骨折的年龄相关模式,从卡贝尔亨廷顿医院和圣玛丽医疗中心的病人记录,为期五年。该研究队列包括623名患者,分为三个年龄组:年龄<22岁,22-65岁的人,以及65岁以上的个人。数据分析涉及对损伤机制的细致检查,损伤严重程度评分(ISS),住院时间,以及不同年龄队列中手术干预的患病率。结果623例患者中,104人(16.7%)未满22岁,367(58.9%)年龄在22至65岁之间,152人(24.4%)超过65岁。大多数是男性(70%)。跌倒是65岁以上(78%)患者面部骨折的最常见原因,虽然攻击在22-65岁年龄段占主导地位(24%),以及22岁以下儿童的机动车碰撞(MCV)(34%)。不同年龄段的ISS中位数和住院时间相似。28%的患者接受了手术,年龄组间有显著差异(p<0.001):<22岁时为38%,33%,22-65年,以及超过65年的11%。下颌骨骨折在年轻患者中更为普遍,<22年的比率为12%,而>65年的比率为5.3%。Logistic回归分析显示,22~65岁的患者接受手术的几率是手术的4.10倍(95%CI=2.38,7.45,p<0.001),而22岁以下的人群的几率是65岁以上人群的5.14倍(95%CI=2.73,10.0,p<0.001)。在22-65岁的患者中,下颌和双侧下颌结局存在显着相关性。讨论这些发现强调了量身定制的预防策略和针对特定年龄的治疗方案以优化患者结果的必要性。针对老年人的跌倒预防措施和针对年轻人的运动相关伤害的干预措施至关重要。此外,该研究强调了为老年患者提供专门护理方案的必要性,以最大限度地减少住院时间并有效管理与年龄相关的合并症.往前走,进一步的研究应该解决局限性,验证调查结果,并探索具体干预措施的有效性,从而为针对阿巴拉契亚地区受创伤性面部骨折影响的不同年龄段的人群,加强预防措施和管理策略铺平了道路。
    Introduction Traumatic facial injuries, leading to facial fractures represent a significant subset of traumatic events, with age emerging as a crucial determinant influencing both their etiology and outcomes. Understanding the age-related patterns of traumatic facial fractures is essential for developing targeted prevention and management strategies. In this context, the Appalachian tri-state area stands as an underexplored region concerning this issue, necessitating comprehensive research to elucidate the nuances of age-related traumatic facial fractures within this geographic context. Methods This retrospective study delves into the age-related patterns of traumatic facial fractures within the Appalachian tri-state area, drawing upon patient records from Cabell Huntington Hospital and Saint Mary\'s Medical Center spanning a five-year period. The study cohort encompasses 623 patients categorized into three age groups: individuals aged <22 years, those aged 22-65 years, and individuals over 65 years. Data analysis involves meticulous examination of mechanisms of injury, injury severity scores (ISSs), hospital length of stay, and the prevalence of surgical interventions across different age cohorts. Results Out of 623 patients, 104 (16.7%) were under 22 years old, 367 (58.9%) were between 22 and 65 years old, and 152 (24.4%) were over 65 years old. The majority were male (70%). Falls were the most common cause of facial fractures in patients over 65 (78%), while assaults were predominant in the 22-65 age group (24%), and motor vehicle collisions (MCVs) in those under 22 (34%). The median ISS and hospital stay durations were similar across age groups. 28% of patients underwent surgery, with significant variation among age groups (p<0.001): 38% for <22 years, 33% for 22-65 years, and 11% for >65 years. Mandibular fractures were more prevalent in younger patients, with rates of 12% for <22 years compared to 5.3% for >65 years. Logistic regression analysis revealed that patients aged 22-65 had 4.10 times higher odds (95% CI=2.38, 7.45, p<0.001) of undergoing surgery, while those under 22 had 5.14 times higher odds (95% CI=2.73, 10.0, p<0.001) compared to those over 65. Significant associations were found for mandibular and bilateral mandibular outcomes in patients aged 22-65 years. Discussion These findings underscore the imperative for tailored prevention strategies and age-specific treatment protocols to optimize patient outcomes. Fall prevention initiatives for the elderly and interventions addressing sports-related injuries for younger individuals are paramount. Moreover, the study highlights the necessity of specialized care protocols for elderly patients to minimize hospital stay durations and manage age-related comorbidities effectively. Moving forward, further research should address limitations, validate findings, and explore the efficacy of specific interventions, thereby paving the way for enhanced preventive measures and management strategies tailored to the diverse age cohorts affected by traumatic facial fractures in the Appalachian region.
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  • 文章类型: Journal Article
    目的:眶底经常受累于头部外伤。目前关于使用重建材料进行轨道地板修复的证据尚无定论。因此,本研究旨在比较聚二恶烷酮(PDS)箔厚度对孤立眶底骨折后眶几何结构重建的影响。
    方法:在提供22个轨道的11具尸体头部中对称地创建标准化的孤立眼眶底骨折。插入厚度为0.25-0.5mm的PDS箔。计算机断层扫描(CT)扫描的本地,骨折,并获得了重建的轨道,和轨道体积,轨道高度,和箔弯曲进行了测量。
    结果:产生孤立的眶底骨折后,眼眶体积和高度显着增加(p<0.01),并且在眶底重建后过度矫正眼眶几何结构显着(p=0.001)减少PDS0.25mm或PDS0.5mm。轨道几何形状重建率相对于箔厚度没有显着差异。然而,与PDS0.5毫米相比,使用0.25mm的PDS在数量上提高了重建精度,并恢复了与初始体积无显著差异的轨道体积.
    结论:无论箔片厚度如何,使用PDS成功重建了孤立骨折的轨道地板,轨道几何的过度校正。由于其较低的弯曲刚度,PDS0.25mm似乎比PDS0.5mm提供更准确的轨道几何重建,尽管在这项尸体研究中,PDS0.25mm和PDS0.5mm的重建准确性没有显着差异。
    OBJECTIVE: The orbital floor is frequently involved in head trauma. Current evidence on the use of reconstruction materials for orbital floor repair is inconclusive. Accordingly, this study aimed to compare the impact of polydioxanone (PDS) foil thickness on reconstruction of the orbital geometry after isolated orbital floor fractures.
    METHODS: Standardized isolated orbital floor fractures were symmetrically created in 11 cadaver heads that provided 22 orbits. PDS foils with thicknesses of 0.25-0.5 mm were inserted. Computed tomography (CT) scans of the native, fractured, and reconstructed orbits were obtained, and orbital volume, orbital height, and foil bending were measured.
    RESULTS: Orbital volume and height significantly (p < 0.01) increased after the creation of isolated orbital floor fractures and significantly (p = 0.001) decreased with overcorrection of the orbital geometry after orbital floor reconstruction with PDS 0.25 mm or PDS 0.5 mm. The orbital geometry reconstruction rate did not differ significantly with respect to foil thickness. However, compared to PDS 0.5 mm, the use of PDS 0.25 mm resulted in quantitatively higher reconstructive accuracy and a restored orbital volume that did not significantly differ from the initial volume.
    CONCLUSIONS: Orbital floors subjected to isolated fractures were successfully reconstructed using PDS regardless of foil thickness, with overcorrection of the orbital geometry. Due to its lower flexural stiffness, PDS 0.25 mm appeared to provide more accurate orbital geometry reconstruction than PDS 0.5 mm, although no significant difference in reconstructive accuracy between PDS 0.25 mm and PDS 0.5 mm was observed in this cadaveric study.
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  • 文章类型: Journal Article
    背景:有效手术进入眶底可促进手术并减轻术后并发症(PC)。这项研究的目的是比较经结膜前和经结膜后间隔入路(PS-TCA/RS-TCA)治疗孤立性眶底骨折(OFF)的PC。
    方法:使用双盲,非自卑,随机化,分面研究设计,纳入年龄≥18岁的双侧隔离OFF患者.通过功率分析确定每组177只眼的样品大小。主要预测变量是手术方法,主要结果是6个月的PC率。统计分析的显著性水平为0.05,相对风险(RR)为0.045的非劣效性界限。
    结果:最终样本包括193名患者(23.3%为女性;年龄,42.8±18.1年)。两种TCA变体均表现出可比的PC率(PS-TCA的5.2%与RS-TCA为7.3%;P=0.53;绝对风险,+2.07%[95%CI,-2.74%至6.89%];RR,1.4[95%CI,0.64至3.07])。大约每49名患者中就有一名患有RS-TCA的PC(伤害所需的人数,48.3).
    结论:两种TCA方法均可在术后6个月无不同PC率的情况下使用。未来的研究应集中在TCA与其他手术方法的结合以进行多个眶壁重建。
    BACKGROUND: Effective surgical access to the orbital floor facilitates surgery and mitigates postoperative complications (PC). The aim of this study was to compare PC between the preseptal and retroseptal transconjunctival approaches (PS-TCA/RS-TCA) for isolated orbital floor fracture (OFF).
    METHODS: Using a double-blind, non-inferiority, randomized, split-face study design, patients aged ≥ 18 years with bilateral isolated OFF were enrolled. A sample size of 177 eyes per group was determined through power analysis. The primary predictor variable was the surgical approach, and the main outcome was the PC rate at month 6. Statistical analyses were computed with a significance level at 0.05 and the non-inferiority margin at a relative risk (RR) of 0.045.
    RESULTS: The final sample included 193 patients (23.3 % female; age, 42.8 ± 18.1 years). Both TCA variants exhibited comparable PC rates (5.2 % for PS-TCA vs. 7.3 % for RS-TCA; P = 0.53; absolute risk, +2.07 % [95 % CI, -2.74 % to 6.89 %]; RR, 1.4 [95 % CI, 0.64 to 3.07]). Approximately one in every 49 patients experiencing PC with RS-TCA (number needed to harm, 48.3).
    CONCLUSIONS: Both TCA methods can be used without different PC rates at 6 months postoperatively. Future research should focus on TCA in combination with other surgical approaches for multiple orbital wall reconstruction.
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  • 文章类型: Journal Article
    在颅颌面外伤中经常注意到眼眶骨折。解剖结构的复杂性和与各种重要结构的接近性通常使这些骨折的手术管理复杂化。因此,作者试图以简化的方式回顾有关骨性眼眶及其软组织包膜的解剖结构的文献,并适当强调手术解剖学和手术角度对眼眶的探索。这篇叙述性文献综述的内容可能对年轻的颌面外科医生有用,并将有助于治疗眼眶骨折。
    Fractures of the orbit are frequently noted in craniomaxillofacial trauma. The complexity of the anatomy and the proximity to various vital structures often complicates the surgical management of these fractures. The authors have thus attempted to review the literature on anatomy of the bony orbit and its soft tissue envelope in a simplified manner with due emphasis on surgical anatomy and exploration of the orbit with a surgical perspective. The contents of this narrative literature review may be useful for young maxillofacial surgeons and will aid in the process of management of orbital fractures.
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  • 文章类型: Journal Article
    背景:交通创伤可导致眼部损伤。开放性眼球损伤通常预后较差,可以通过及时诊断和适当的治疗来改善。尽管如此,很少有研究关注交通事故后患者的视觉结果。在这项研究中,我们的目的是研究在一家三级眼科医院发生交通事故后患者眼部并发症的特点和预后。
    方法:我们将44例交通事故患者(88只眼)分为两组,其矫正视力与初始表现时最小分辨率0角的对数相同或更好(更好组)和更差(更差组)。最终矫正远距视力,眼内压,角膜损伤,外伤性白内障的存在,并对两组治疗情况进行比较。此外,我们进行了多元线性回归分析,以确定与最终视力相关的因素.
    结果:地球挫伤,眼眶爆裂性骨折,外伤性虹膜炎,滑车神经麻痹占14.8%,3.4%,2.3%,2.3%的病人,分别。17.0%和9.1%的患者进行了局部滴注和眼科治疗/手术,分别。较好组(68只眼)的最终视力明显优于较差组(20只眼)(P<0.001)。然而,人口统计学特征无组间差异.多变量分析表明,初始视力和最终视力之间存在显着相关性(P<0.001)。
    结论:在初始表现时评估视力对于预测最终视力至关重要。我们的发现将有助于告知眼科医生,以改善交通事故后患者眼外伤的预后和治疗。
    BACKGROUND: Traffic trauma can lead to ocular damage. Open globe injuries usually have a poor prognosis, which can be ameliorated by prompt diagnosis and appropriate treatment. Nonetheless, few studies have focused on the visual outcomes of patients following traffic accidents. In this study, we aimed to examine the characteristics and prognosis of ocular complications in patients following traffic accidents at a specialized tertiary eye hospital.
    METHODS: We classified 44 patients from traffic accidents (88 eyes) into groups with equal or better (better group) and worse (worse group) corrected-distance visual acuity than a logarithm of the minimum angle of resolution 0 at the initial presentation. Final corrected-distance visual acuity, intraocular pressure, corneal injury, presence of traumatic cataracts, and treatment were compared between the groups. In addition, a multivariate linear regression analysis was performed to identify factors associated with the final visual acuity.
    RESULTS: Globe contusion, orbital blowout fracture, traumatic iritis, and trochlear nerve palsy were observed in 14.8%, 3.4%, 2.3%, and 2.3% of the patients, respectively. Topical instillation and ophthalmological treatment/surgery were performed in 17.0% and 9.1% of the patients, respectively. The better group (68 eyes) had significantly better final visual acuity than the worse group (20 eyes) (P < 0.001). However, there was no between-group difference in demographic characteristics. Multivariate analysis demonstrated that there was a significant correlation between the initial and final visual acuities (P < 0.001).
    CONCLUSIONS: Assessing visual acuity at the initial presentation is crucial for predicting the final visual acuity. Our findings will help to inform ophthalmologists aiming to improve the prognosis and treatment of ocular trauma in patients following traffic accidents.
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  • 文章类型: Case Reports
    小儿人群中的眼眶骨折很少见。活板门骨折是一种特殊的解剖学类型的眼眶骨折,与眼眶内容物突出和眼外肌压迫有关,没有任何软组织创伤的迹象。诊断延迟会导致一种威胁生命的疾病,称为眼心反射,以恶心为特征,呕吐,心动过缓,和晕厥。许多作者建议早期手术干预,但是有些患者可能会因为各种原因而延误。我们在此代表三例眼眶骨折,以防止长期持续性复视。根据情况,对2例患者进行了手术,其中一名患者进行了自体髂骨皮质移植物,以防止术后眼眶内容物突出,一个病人,只释放被困的肌肉。对一名患者进行了保守管理,并进行了定期随访。
    Orbital fractures in the pediatric population are rare. A trapdoor fracture is a special anatomic type of orbital fracture associated with herniation of orbital contents and entrapment of extraocular muscles entrapment with no signs of any soft tissue trauma. A delay in diagnosis can lead to a life-threatening condition known as oculocardiac reflex, characterized by nausea, vomiting, bradycardia, and syncope. Many authors recommend early surgical intervention, but some patients may delay for various reasons. We hereby represent three cases of orbital fracture to prevent long-term persistent diplopia. Depending on the case scenario, two cases were operated on in which an autogenous iliac cortical graft was placed in one patient to prevent postoperative herniation of orbital content, and in one patient, only release of entrapped muscles was done. One patient was managed conservatively with a regular follow-up visit.
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  • 文章类型: Journal Article
    目的:确定眼眶骨折(SCGI)严重闭眼损伤的危险因素,并建立预测SCGI的最佳多变量模型。
    方法:对2016年至2022年在Farabi医院诊断为眼眶骨折的患者进行了回顾性研究。包括接受全面眼科检查和眼眶CT扫描的患者。通过逻辑回归(LR)分析确定SCGI的预测体征或影像学发现。支持向量机(SVM)随机森林回归(RFR),和极端梯度增强(XGBoost)也使用五倍交叉验证方法进行训练。
    结果:共纳入403例患者的415只眼。与SCGI风险增加相关的因素是未矫正视力(UCVA)降低,外伤眼与对侧眼的UCVA之间的差异增加,年龄较大,男性,眶周软组织创伤分级,职业环境中的创伤,结膜出血,眼外活动限制,裂缝壁的数量,存在内侧壁骨折,骨折的大小,眶内气肿和球后出血。LR的接收机工作特性曲线下的面积,SVM,RFR,XGBoost对SCGI的预测为57.2%,68.8%,63.7%,73.1%,分别。
    结论:临床和影像学检查结果可用于有效预测SCGI。XGBoost在预测SCGI方面优于逻辑回归模型,可以纳入临床实践。
    OBJECTIVE: To determine risk factors for substantial closed-globe injuries in orbital fractures (SCGI) and to develop the best multivariate model for the prediction of SCGI.
    METHODS: A retrospective study was performed on patients diagnosed with orbital fractures at Farabi Hospital between 2016 and 2022. Patients with a comprehensive ophthalmologic examination and orbital CT scan were included. Predictive signs or imaging findings for SCGI were identified by logistic regression (LR) analysis. Support vector machine (SVM), random forest regression (RFR), and extreme gradient boosting (XGBoost) were also trained using a fivefold cross-validation method.
    RESULTS: A total of 415 eyes from 403 patients were included. Factors associated with an increased risk of SCGI were reduced uncorrected visual acuity (UCVA), increased difference between UCVA of the traumatic eye from the contralateral eye, older age, male sex, grade of periorbital soft tissue trauma, trauma in the occupational setting, conjunctival hemorrhage, extraocular movement restriction, number of fractured walls, presence of medial wall fracture, size of fracture, intraorbital emphysema and retrobulbar hemorrhage. The area under the curve of the receiver operating characteristic for LR, SVM, RFR, and XGBoost for the prediction of SCGI was 57.2%, 68.8%, 63.7%, and 73.1%, respectively.
    CONCLUSIONS: Clinical and radiographic findings could be utilized to efficiently predict SCGI. XGBoost outperforms the logistic regression model in the prediction of SCGI and could be incorporated into clinical practice.
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  • 文章类型: Journal Article
    目的:分析眼眶骨折重建术后并发症的类型和原因,提高临床医师处理或预防此类并发症的能力。
    方法:我们进行了回顾性病例系列分析,回顾性收集2012年5月至2022年5月在南昌大学附属眼科医院接受手术治疗的眼眶骨折患者的临床资料。描述性统计用于记录常见的术后并发症,我们记录了至少6个月随访后持续的并发症.
    结果:在227例接受眼眶骨折手术的患者中,他们被随访了6到36个月,15例发生并发症,导致发病率为6.61%。这些并发症包括植入材料感染和排斥(4例),持续性复视(3例),眶内血肿(2例),顿唇(2例),下眼睑外翻或缩回(2例),和皮肤疤痕(2例)。术后感染的主要原因是鼻旁窦或骨折区域内闭合腔的慢性炎症。眼眶骨折术后并发症与多种因素相关,包括手术的时机,手术方法,修复材料,手术技巧,和辅助技术。
    结论:规范手术技术,实施精准辅助技术,可降低并发症发生率,提高手术成功率。
    OBJECTIVE: To analyze the types and causes of complications following orbital fracture reconstruction and enhance clinicians\' capacity to manage or prevent such complications.
    METHODS: We conducted a retrospective case series analysis, retrospectively collecting and analyzing clinical data of patients with orbital fractures who received surgical treatment at the Affiliated Eye Hospital of Nanchang University from May 2012 to May 2022. Descriptive statistics were employed to document common postoperative complications, and we recorded complications persisting after a minimum 6-month follow-up period.
    RESULTS: Among the 227 patients who underwent orbital fracture surgery, they were followed up for 6 to 36 months, and complications occurred in 15 cases, resulting in an incidence rate of 6.61%. These complications included implant material infections and rejections (4 cases), persistent diplopia (3 cases), intraorbital hematomas (2 cases), epiphora (2 cases), lower eyelid eversion or retraction (2 cases), and skin scars (2 cases). The primary cause of postoperative infection was chronic inflammation in the paranasal sinuses or closed cavities within the fracture area. Postoperative complications in orbital fractures were associated with various factors, including the timing of surgery, surgical approach, repair materials, surgical skills, and auxiliary techniques.
    CONCLUSIONS: Standardizing surgical techniques and implementing precise auxiliary technologies may reduce the incidence of complications and enhance the operation\'s success rate.
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  • 文章类型: Journal Article
    目的:这项初步研究旨在评估使用3D预制眼眶钛网(3D-POTM)进行计算机辅助手术方案的可行性和有效性,术前虚拟规划和术中导航在原发性眶内骨折重建中的应用。
    方法:在2021年3月至2023年3月期间,对接受3D-POTM治疗的单侧眼眶内骨折手术患者的围手术期数据进行分析。使用未受影响的对侧镜像作为参考,使用预制网格的标准三角形语言文件进行术前虚拟规划。术中使用导航。重建精度取决于:术后重建网格位置与术前虚拟计划之间的对应关系以及重建和未受影响的眼眶体积之间的差异。评估术前和术后复视和眼球内陷。
    结果:纳入26例患者。14例(53.8%)患者报告了孤立性眶底骨折,同时,内侧壁和地板占12例(46.1%)。最终平板位置与理想数字计划之间的平均差异为0.692mm(95%CI:0.601-0.783)。重建和未受影响的轨道之间的平均体积差为1.02mL(95%CI:0.451-1.589)。所有病例的术前复视均得到解决,21例患者中有19例(76.2%)眼球内陷。
    结论:所提出的方案是早期治疗眶内骨折的适应性和可靠的工作流程。它可以实现精确的术前计划和术中程序,减轻陷阱和并发症,并提供出色的重建,同时保持合理的成本和承诺时间。
    OBJECTIVE: This pilot study aims to evaluate the feasibility and effectiveness of computer-assisted surgery protocol with 3D-preformed orbital titanium mesh (3D-POTM), using presurgical virtual planning and intraoperative navigation in primary inferomedial orbital fracture reconstruction.
    METHODS: Between March 2021 and March 2023, perioperative data of patients undergoing surgery for unilateral inferomedial orbital fracture treated with 3D-POTM were analyzed. Presurgical virtual planning with a Standard Triangle Language file of preformed mesh was conducted using the mirrored unaffected contralateral side as a reference, and intraoperative navigation was used. The reconstruction accuracy was determined by: correspondence between postoperative reconstruction mesh position with presurgical virtual planning and difference among the reconstructed and the unaffected orbital volume. Pre- and postoperative diplopia and enophthalmos were assessed.
    RESULTS: Twenty-six patients were included. Isolated orbital floor fracture was reported in 14 (53.8%) patients, meanwhile medial wall and floor one in 12 (46.1%) cases. The mean difference between final plate position and ideal digital plan was 0.692 mm (95% CI: 0.601-0.783). The mean volume difference between reconstructed and unaffected orbit was 1.02 mL (95% CI: 0.451-1.589). Preoperative diplopia was settled out in all cases and enophthalmos in 19 (76.2%) of 21 patients.
    CONCLUSIONS: The proposed protocol is an adaptable and reliable workflow for the early treatment of inferomedial orbital fractures. It enables precise preoperative planning and intraoperative procedures, mitigating pitfalls and complications, and delivering excellent reconstruction, all while maintaining reasonable costs and commitment times.
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  • 文章类型: Case Reports
    用于骨重建的非吸收性同种异体眼眶植入物的异物反应在文献中很少记录。我们提出了一个巨大的囊性包囊患者的同种异体眼眶植入物的手术和手术治疗方法,这最终被认为是异物反应的结果。
    一名41岁的男性患者,有右眶底骨折的遥远病史,接受了尼龙箔植入物的修复。20年后,该患者出现进行性同侧眼球突出,并被发现患有巨大的下眶囊肿。进行手术探查和移除植入物和囊。组织病理学证实患者的同种异体植入物周围有延迟的异物反应。
    同种异体植入物可能会导致异物反应和囊肿包裹,这是一种延迟性并发症。
    UNASSIGNED: Foreign body reaction to non-absorbable alloplastic orbital implants utilized for bony reconstruction are infrequently documented in the literature. We present the workup and surgical management of a giant cystic mass encapsulating a patient\'s alloplastic orbital implant, which was ultimately deemed to be a result of foreign body reaction.
    UNASSIGNED: A 41-year-old male patient with distant history of a right orbital floor fracture had undergone repair with the placement of a nylon foil implant. The patient presented twenty years later with progressive ipsilateral globe proptosis and was found to have a giant inferior orbital cyst. Surgical exploration and removal of the implant and capsule were performed. Histopathology confirmed a delayed foreign body reaction around the patient\'s alloplastic implant.
    UNASSIGNED: Alloplastic implants may result foreign body reaction and cyst encapsulation as a delayed complication.
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