光镊子(OTs)可以将光动量传递给粒子,通过光学力实现粒子的精确操纵。由于非接触和精确控制的特性,光学器件为探索非线性光学背后的奥秘提供了门户,软凝聚态物理,分子生物学,和分析化学。近年来,OTs已经与微流控芯片结合在一起,以克服它们在以下方面的局限性:例如,速度和效率,创造一种被称为“光流控镊子”的技术。\“本文首先简要介绍静态OTs。接下来,我们概述了光流控镊子的最新发展,总结捕获方面的进步,操纵,排序,和基于不同技术的测量。重点是各种光流控镊子,比如全息光镊子,光子晶体光镊子,和波导光镊子。此外,将光流控镊子与其他技术相结合以实现更大的功能是一种持续的趋势,如抗原-抗体相互作用和拉曼镊子。最后,我们总结了该研究领域的主要挑战和未来发展方向。
Optical tweezers (OTs) can transfer light momentum to particles, achieving the precise manipulation of particles through optical forces. Due to the properties of non-contact and precise control, OTs have provided a gateway for exploring the mysteries behind nonlinear optics, soft-condensed-matter physics, molecular biology, and analytical chemistry. In recent years, OTs have been combined with microfluidic chips to overcome their limitations in, for instance, speed and efficiency, creating a technology known as \"optofluidic tweezers.\" This paper describes static OTs briefly first. Next, we overview recent developments in optofluidic tweezers, summarizing advancements in capture, manipulation, sorting, and measurement based on different technologies. The focus is on various kinds of optofluidic tweezers, such as holographic optical tweezers, photonic-crystal optical tweezers, and waveguide optical tweezers. Moreover, there is a continuing trend of combining optofluidic tweezers with other techniques to achieve greater functionality, such as antigen-antibody interactions and Raman tweezers. We conclude by summarizing the main challenges and future directions in this research field.