防晒剂是含有任何数量的紫外线过滤剂(UVF)的局部制剂。审查的第一部分将集中在2019年最近的食品和药物管理局(FDA)法规以及这些药物的一般用途。虽然防晒产品在美国越来越受到监管,我们在UVF的选择上仍然落后于其他国家。防晒以防止皮肤癌和老化变化应该是避免阳光的结合,保护结构,和服装以及防晒产品的使用。需要更新和更安全的产品来帮助补充和替换旧的药物,并提高其化妆品的可接受性。这将是对成分的审查,局部毒性(即接触性皮炎,光接触性皮炎),对儿童的特殊考虑,和防晒制剂的外观。第二部分将关注环境,与UVFs越来越相关的生态和人类毒性。
Sunscreens are topical preparations containing any number of ultraviolet filters (UVFs). The first part of the review will focus on the recent Food and Drug Administration (FDA) regulations of 2019 and general use of these agents. While sunscreen products are becoming more regulated in the United States, we still lag behind other countries in our options for UVFs. Sun protection to prevent skin cancer and aging changes should be a combination of sun avoidance, protective structures, and clothing as well as use of sunscreen products. Newer and safer products are needed to help supplement and replace older agents as well as improve their cosmetic acceptability. This will be a review of ingredients, local toxicities (i.e. contact dermatitis, photocontact dermatitis), special considerations for children, and cosmesis of sunscreen preparations. Part 2 will focus on the environmental, ecological and human toxicities that have been increasingly related to UVFs.