Multimode

多模
  • 文章类型: Journal Article
    从中国卫生规划者和政策制定者的角度来看,实现更高水平的社区医疗保健服务的可及性和公平性已成为卫生服务提供的主要关注点。
    在这项研究中,我们引入了一个全面的门到门(D2D)模型,将其与开放的ODAPI结果集成,以精确计算不同运输模式下社区医院的可及性。对于D2D公共交通模式,我们计算了一天中不同时间可达性的时间变化和标准偏差。此外,D2D骑行模式的可访问性值,D2D驱动模式,还计算了简单的驾驶模式进行比较。此外,我们引入Lorenz曲线和Gini指数来评估不同时间和交通方式下社区医疗公平性的差异.
    D2D公共交通模式根据一天中的时间在可及性和公平性方面表现出明显的波动。可达性和公平性受到上午8点至上午11点之间的交通流量的显著影响,而在下午12点到10点期间,在南京,社区医院的开放时间成为更重要的决定因素。整体空间布局最公平和最不公平的时刻是上午10点和下午10点,分别。在四种运输方式中,传统的简单驾驶模式表现出最小的股票指数,基尼系数仅为0.243。相比之下,D2D骑行模式,虽然广泛喜欢获得社区医疗保健服务,基尼值最高,达到0.472。
    所提出的方法将D2D模型与开放ODAPI结果相结合,对于实际运输模式的可访问性计算是有效的。社区医疗保健的空间可达性和公平性受时间变化的影响会出现重大波动。交通方式也是影响可达性和公平性的重要因素。这些结果有助于规划者和学者从不同时间尺度和多方式交通系统的角度建立全面的空间可达性和公平性模型,并优化公共服务设施的选址。
    UNASSIGNED: Achieving a higher level of accessibility and equity to community healthcare services has become a major concern for health service delivery from the perspectives of health planners and policy makers in China.
    UNASSIGNED: In this study, we introduced a comprehensive door-to-door (D2D) model, integrating it with the open OD API results for precise computation of accessibility to community hospitals over different transport modes. For the D2D public transit mode, we computed the temporal variation and standard deviation of accessibility at different times of the day. Additionally, accessibility values for D2D riding mode, D2D driving mode, and simple driving mode were also computed for comparison. Moreover, we introduced Lorenz curve and Gini index to assess the differences in equity of community healthcare across different times and transport modes.
    UNASSIGNED: The D2D public transit mode exhibits noticeable fluctuations in accessibility and equity based on the time of day. Accessibility and equity were notably influenced by traffic flow between 8 AM and 11 AM, while during the period from 12 PM to 10 PM, the open hours of community hospitals became a more significant determinant in Nanjing. The moments with the most equitable and inequitable overall spatial layouts were 10 AM and 10 PM, respectively. Among the four transport modes, the traditional simple driving mode exhibited the smallest equity index, with a Gini value of only 0.243. In contrast, the D2D riding mode, while widely preferred for accessing community healthcare services, had the highest Gini value, reaching 0.472.
    UNASSIGNED: The proposed method combined the D2D model with the open OD API results is effective for accessibility computation of real transport modes. Spatial accessibility and equity of community healthcare experience significant fluctuations influenced by time variations. The transportation mode is also a significant factor affecting accessibility and equity level. These results are helpful to both planners and scholars that aim to build comprehensive spatial accessibility and equity models and optimize the location of public service facilities from the perspective of different temporal scales and a multi-mode transport system.
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  • 文章类型: Journal Article
    本文介绍了一种新颖的单层微带贴片元件,旨在实现宽波束宽度,为了解决现代相控阵系统对广角扫描能力日益增长的需求。拟议要素,包括槽蚀刻的圆形贴片和布置成正方形环的金属化孔阵列,提供了一种独特的光束整形方法。通过仔细调整槽结构和进给位置等参数,我们的元素被设计为同时激发TM01和TM21模式,有助于其宽波束宽度特性的关键特征。通过这些模式的建设性干涉,我们的元素在两个主平面上都展示了大约150°的显着3dB波束宽度,展示其在广角扫描应用中的潜力。为了验证该提议元素的实际性能,制造了两个线性相控阵列并进行了实验评估。仿真结果证实了天线在E平面和H平面中的广角扫描能力。此外,实验评估表明,这些线性相控阵可以有效地产生25GHz至28GHz频率范围内的扫描光束,覆盖从-60°到60°的宽角度范围,同时保持增益损失在3dB以内。这种创新的设计方法不仅为实现微带贴片元件的宽波束宽度提供了一个有前途的解决方案,而且还具有开发具有广角扫描能力的高性价比相控阵的巨大潜力,为相控阵技术的进步做出了宝贵的贡献。
    This paper introduces a novel single-layer microstrip patch element designed to achieve a wide beamwidth, in order to address the growing demand for wide-angle scanning capabilities in modern phased array systems. The proposed element, comprising a slot-etched circular patch and an array of metallized holes arranged in square rings, offers a unique approach to beam shaping. By carefully adjusting parameters such as the slot structure and feeding position, our element is engineered to simultaneously excite both the TM01 and TM21 modes, a key feature that contributes to its wide beamwidth characteristics. Through the constructive interference of these modes, our element demonstrates a remarkable 3 dB beamwidth of approximately 150° in both principal planes, showcasing its potential for wide-angle scanning applications. To validate the practical performance of this proposed element, two linear phased arrays are manufactured and experimentally evaluated. The simulation results confirm the wide-angle scanning capability of the antennas in both the E-plane and H-plane. Furthermore, the experimental assessment demonstrates that these linear phased arrays can effectively generate scanning beams within a frequency range of 25 GHz to 28 GHz, covering a wide angular range from -60° to 60°, while maintaining a gain loss within 3 dB. This innovative design approach not only offers a promising solution for achieving a wide beamwidth in microstrip patch elements, but also holds significant potential for the development of cost-effective phased arrays with wide-angle scanning capabilities, making it a valuable contribution to the advancement of phased array technology.
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  • 文章类型: Journal Article
    采用65nmCMOS技术实现了具有多模操作的28GHz全差分八通道波束成形IC(BFIC),用于相控阵收发器。BFIC在每个信道上具有可调节的增益和相位控制,以实现精细的波束控制和波束方向图。BFIC具有八个差分波束形成通道,每个通道由带有精确增益控制电路的两级双向放大器组成,六位移相器,三位数字步进衰减器,以及用于振幅和相位变化补偿的调谐位。差分八通道BFIC的Tx和Rx模式总增益约为11dB和9dB,分别,在27.0-29.5GHz。Tx模式和Rx模式的回波损耗在27.0-29.5GHz处>10dB。最大相位为354°,相位分辨率为5.6°,最大衰减为31dB,包括衰减分辨率为1dB的增益控制位,在27.0-29.5GHz时实现。在27.0-29.5GHz时,均方根(RMS)相位和幅度误差<3.2°和<0.6dB,分别。芯片尺寸为3.0×3.5mm2,包括焊盘,和Tx模式电流消耗为580mA在2.5V电源电压。
    A 28 GHz fully differential eight-channel beamforming IC (BFIC) with multimode operations is implemented in 65 nm CMOS technology for use in phased array transceivers. The BFIC has an adjustable gain and phase control on each channel to achieve fine beam steering and beam pattern. The BFIC has eight differential beamforming channels each consisting of the two-stage bi-directional amplifier with a precise gain control circuit, a six-bit phase shifter, a three-bit digital step attenuator, and a tuning bit for amplitude and phase variation compensation. The Tx and Rx mode overall gains of the differential eight-channel BFIC are around 11 dB and 9 dB, respectively, at 27.0-29.5 GHz. The return losses of the Tx mode and Rx mode are >10 dB at 27.0-29.5 GHz. The maximum phase of 354° with a phase resolution of 5.6° and the maximum attenuation of 31 dB, including the gain control bits with an attenuation resolution of 1 dB, is achieved at 27.0-29.5 GHz. The root mean square (RMS) phase and amplitude errors are <3.2° and <0.6 dB at 27.0-29.5 GHz, respectively. The chip size is 3.0 × 3.5 mm2, including pads, and Tx mode current consumption is 580 mA at 2.5 V supply voltage.
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  • 文章类型: Journal Article
    在这项工作中,制备了具有模拟过氧化物酶活性和荧光猝灭特性的Ti3C2纳米酶(Ti3C2NEs)材料。然后使用6-羧基荧光素(FAM)标记的黄曲霉毒素B1(AFB1)适体对Ti3C2NEs进行功能化,构建了一种新型多模纳米酶生物传感器,用于检测花生中的AFB1。基于Ti3C2NES的荧光猝灭特性和优越的模拟过氧化物酶活性以及适配体与AFB1的特异性结合,实现了AFB1的灵敏、快速的荧光/比色/智能手机检测,检测限分别为0.09ngmL-1、0.61ngmL-1和0.96ngmL-1。提供的分析方法不仅可以在多种模式下检测AFB1,而且检测范围更广,较低的检测限(LOD)和更好的回收率,并能实现花生中AFB1含量的现场准确检测,在食品质量检测领域具有很大的应用潜力。
    In this work, Ti3C2 nano-enzymes (Ti3C2 NEs) materials with simulated peroxidase activity and fluorescence quenching properties were prepared. Then Ti3C2 NEs was functionalized using 6-carboxyfluorescein (FAM) labeled Aflatoxin B1 (AFB1) aptamers to construct a novel multimode nano enzyme biosensor for the detection of AFB1 in peanuts. Based on the fluorescence quenching characteristics and the superior simulated peroxidase activity of Ti3C2 NES and the specific binding of the aptamer to AFB1, the sensitive and rapid fluorescence/colorimetric/smart phone detection of AFB1 have been achieved, with detection limits of 0.09 ng mL-1, 0.61 ng mL-1 and 0.96 ng mL-1, respectively. The analytical method provided can not only detect AFB1 in multiple modes, but also has a wider detection range, lower limit of detection (LOD) and better recovery rate, and can achieve on-site accurate detection of AFB1 content in peanuts, which has great application potential in the field of food quality testing.
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  • 文章类型: Journal Article
    背景:在美国进行的全国家庭成长调查(NSFG)和妊娠风险评估监测系统(PRAMS)等研究收集了有关妊娠意向的数据,以帮助改善健康教育,服务,和程序。PRAMS从特定站点收集数据,NSFG是一项基于家庭的全国性调查。像NSFG一样,妇女调查旨在使用基于地址的样本和多模式数据收集方法对居住在家庭中的参与者进行调查。妇女调查从美国9个州的合格参与者那里收集了关于避孕方法使用的数据,生殖健康,怀孕的意图。在本文中,我们专注于基线数据收集协议,包括样本设计,数据收集程序,和数据处理。我们还简要讨论了后续调查和终点线调查方法。我们的目标是向其他研究人员通报在进行家庭水平的生殖健康调查时要考虑的方法。
    目标:制定妇女调查是为了支持特定国家的研究和评估项目,总体目标是了解18-44岁女性的避孕保健方法。该项目从9个不同州的受访者那里收集数据(亚利桑那州,阿拉巴马,特拉华州,爱荷华州,马里兰,新泽西,俄亥俄州,南卡罗来纳州,和威斯康星州)多轮。
    方法:使用基于地址的抽样方法随机选择家庭。该项目包括横断面基线调查,2或3次后续调查,由一个选择加入的受访者小组进行,和横截面端线测量。每轮数据收集都通过使用编程的网络调查和格式化的硬拷贝调查表来使用多模式设计。来自随机选择的家庭的参与者通过网络调查或邮寄硬拷贝问卷来访问他们的个性化调查。为了最大限度地回应,这些调查遵循严格的时间表,包括各种提示,以支持调查实施设计,参与者获得了适度的货币激励。
    结果:这是一个正在进行的项目,其结果由参与数据分析的评估团队单独发布。
    结论:第一次基线调查中使用的方法对后续全州范围调查中使用的方法进行了修改。从这个项目收集的数据将提供洞察妇女的生殖健康,使用避孕药,和9个选定州的堕胎态度。该项目的长期目标是使用一种数据收集方法,从具有代表性的参与者样本中收集数据,以评估生殖健康行为随时间的变化。
    未经评估:DERR1-10.2196/40675。
    BACKGROUND: Studies conducted in the United States such as the National Survey of Family Growth (NSFG) and the Pregnancy Risk Assessment Monitoring System (PRAMS) collect data on pregnancy intentions to aid in improving health education, services, and programs. PRAMS collects data from specific sites, and NSFG is a national household-based survey. Like NSFG, the Surveys of Women was designed to survey participants residing in households using an address-based sample and a multimode data collection approach. The Surveys of Women collects data from eligible participants in 9 states within the United States on contraception use, reproductive health, and pregnancy intentions. In this paper, we focus on the baseline data collection protocol, including sample design, data collection procedures, and data processing. We also include a brief discussion on the follow-up and endline survey methodologies. Our goal is to inform other researchers on methods to consider when fielding a household-level reproductive health survey.
    OBJECTIVE: The Surveys of Women was developed to support state-specific research and evaluation projects, with an overall goal of understanding contraceptive health practices among women aged 18-44 years. The project collects data from respondents in 9 different states (Arizona, Alabama, Delaware, Iowa, Maryland, New Jersey, Ohio, South Carolina, and Wisconsin) over multiple rounds.
    METHODS: Households were selected at random using address-based sampling methods. This project includes a cross-sectional baseline survey, 2 or 3 follow-up surveys with an opt-in panel of respondents, and a cross-sectional endline survey. Each round of data collection uses a multimode design through the use of a programmed web survey and a formatted hard copy questionnaire. Participants from the randomly selected households access their personalized surveys through a web survey or mail in a hard copy questionnaire. To maximize responses, these surveys follow a rigorous schedule of various prompts bolstering the survey implementation design, and the participants received a modest monetary incentive.
    RESULTS: This is an ongoing project with results published separately by the evaluation teams involved with data analysis.
    CONCLUSIONS: The methods used in the first baseline survey informed modifications to the methods used in subsequent statewide surveys. Data collected from this project will provide insight into women\'s reproductive health, contraceptive use, and abortion attitudes in the 9 selected states. The long-term goal of the project is to use a data collection methodology that collects data from a representative sample of participants to assess changes in reproductive health behaviors over time.
    UNASSIGNED: DERR1-10.2196/40675.
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  • 文章类型: Journal Article
    这项工作提出了一种基于双自由度交叉梁的新型鸟形宽带压电能量采集器,用于低频环境振动。收割机的特点是安装在双铰接梁上的悬臂,其旋转运动有效地减少其固有频率。基于有限元方法进行了数值仿真,分析了所提出的收割机的模态形状和谐波响应。制作原型,并通过测试系统进行实验,其结果表明与仿真有很好的一致性。多频率能量收集是在第一,第二-,和五阶共振。特别是,所提出的采集器在低至19.23HZ和45.38Hz的频率下具有9.53mW和1.83mW的显着输出特性,优于大多数现有的能量采集器。此外,实验研究了关键参数对收割性能的影响,以优化收割机的环境适应性。这项工作为有效地收集低频振动能量提供了一个新的视角,可用于为电子设备供电。
    This work presents a novel bird-shaped broadband piezoelectric energy harvester based on a two-DOF crossed beam for low-frequency environmental vibrations. The harvester features a cantilever mounted on a double-hinged beam, whose rotating motions effectively diminish its natural frequencies. Numerical simulation based on the finite element method is conducted to analyze the modal shapes and the harmonic response of the proposed harvester. Prototypes are fabricated and experiments are carried out by a testing system, whose results indicate a good agreement with the simulation. The multi-frequency energy harvesting is achieved at the first-, second-, and fifth-order resonances. In particular, the proposed harvester demonstrates the remarkable output characteristics of 9.53 mW and 1.83 mW at frequencies as low as 19.23 HZ and 45.38 Hz, which are superior to the majority of existing energy harvesters. Besides, the influences of key parameters on the harvesting performance are experimentally investigated to optimize the environmental adaptability of the harvester. This work provides a new perspective for efficiently harvesting the low-frequency vibration energy, which can be utilized for supplying power to electronic devices.
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  • 文章类型: Journal Article
    基于碳纳米管(CNT)的化学电阻器由于其固有的纳米级孔隙率和出色的电导率而成为用于气相色谱(GC)的有前途的气体检测器。然而,制造再现性,解吸时间长,灵敏度有限,和低动态范围限制了它们在实际应用中的使用。本文报道了一种新颖的片上单片集成多模CNT传感器,其中基于微机电系统的体声波(BAW)谐振器嵌入在CNT化学电阻器下方。通过使用BAW现场监测CNT沉积,提高了器件制造的可重复性。我们发现声刺激可以加速气体从CNT表面的解吸速率,解决了缓慢的解吸问题。由于不同的传感机制,多模式CNT传感器提供互补的响应目标与改进的灵敏度和动态范围相比,一个单一的模式检测器。通过对设备和分离柱之间的连接进行专门设计,制备了使用多模CNT传感器的色谱系统的原型。这种GC系统用于在不同GC条件下对气体混合物进行定量识别。证明了多模CNT检测器用于色谱分析的可行性。开发的CMOS兼容多模CNT传感器提供高传感性能,小型化尺寸,和低功耗,这对于开发便携式GC至关重要。
    Carbon nanotube (CNT)-based chemiresistors are promising gas detectors for gas chromatography (GC) due to their intrinsic nanoscale porosity and excellent electrical conductivity. However, fabrication reproducibility, long desorption time, limited sensitivity, and low dynamic range limit their usage in real applications. This paper reports a novel on-chip monolithic integrated multimode CNT sensor, where a micro-electro-mechanical system-based bulk acoustic wave (BAW) resonator is embedded underneath a CNT chemiresistor. The device fabrication repeatability was improved by on-site monitoring of CNT deposition using BAW. We found that the acoustic stimulation can accelerate the gas desorption rate from the CNT surface, which solves the slow desorption issue. Due to the different sensing mechanisms, the multimode CNT sensor provides complementary responses to targets with improved sensitivity and dynamic range compared to a single mode detector. A prototype of a chromatographic system using the multimode CNT sensor was prepared by dedicated design of the connection between the device and the separation column. Such a GC system is used for the quantitative identification of a gas mixture at different GC conditions, which proves the feasibility of the multimode CNT detector for chromatographic analysis. The as-developed CMOS compatible multimode CNT sensor offers high sensing performance, miniaturized size, and low power consumption, which are critical for developing portable GC.
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  • 文章类型: Journal Article
    阅读和写作在学习英语口语和综合技能方面具有更大的意义。人工智能(AI)在我们生活的许多方面都很重要,包括教育,healthcare,business,等等。AI使教育系统取得了重大进展。它已迅速上升到最迅速发展的教育技术学科名单的顶部。通过它的创造,人工智能为创造新的教育和知识技术做出了贡献,目前正在广泛的领域进行研究。聊天机器人,机器人助理,Vidreader,看到AI,Classcraft,3D全息图,并开发了其他基于人工智能的计划,以帮助教学人员和学生使用和改进教育系统。在教育领域,AI专注于情感化的人工学习辅助工具和智能教学系统。教育事业的首要目标和宗旨是建设智慧教育系统,由于教学辅助机器人的发展,这现在是可能的,基于AI的智能教室,和英语教学援助,除其他外。现在可以在学习的所有阶段采用人工智能技术来改善教育系统。在COVID-19疾病期间,学生和老师以各种方式在网上进行教育和指导。学习可以数字化完成,这样人们就不会落后于他们的教育。拟议的研究考虑了多准则决策支持系统(MCDM),用于支持AI的英语多模式在线阅读的制作和应用。本研究提供了超级决策工具的应用,以方便实验工作。因此,研究人员将能够找到和设计新的解决方案。
    Reading and writing English have greater significance in learning oral English and comprehensive skills. Artificial Intelligence (AI) is important in many aspects of our lives, including education, healthcare, business, and so on. AI has allowed for significant advancements in the educational system. It has quickly risen to the top of the list of the most rapidly expanding educational technology disciplines. Through its creation, AI has contributed to the creation of new educational and knowledge techniques that are currently being researched across a wide range of fields. Chatbots, Robots\' Assistant, Vidreader, Seeing AI, Classcraft, 3D holograms, and other AI-based programmes were developed to assist both teaching staff and students in using and improving the educational system. In the sphere of education, AI is focusing on sentimentalized artificial learning aids and smart instruction systems. The primary goal and objective of the education business is to construct an intelligent education system, which is now possible thanks to the development of teaching assistant robots, smart classrooms based on AI, and English teaching assistance, among other things. Artificial Intelligence techniques may now be employed at all stages of learning to improve the educational system. During the COVID-19 illness, students and teachers took their education and instruction online in a variety of ways. Learning can be done digitally so that folks do not fall behind in their education. The proposed study has considered multi-criteria decision support systems (MCDM) for AI-enabled production and application of English multimode online reading. This study has offered the application of the super decision tool to facilitate the experimental work. As a result of this, researchers will be able to find and design new solutions to the subject.
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  • 文章类型: Journal Article
    建筑物的冷暖能耗对能源供应构成严重威胁,增加温室气体排放,从而对全球变暖和长期的气候变化趋势产生不利影响。这里,受百叶窗结构的启发,这项工作展示了一种集成辐射冷却的多模态装置,自然采光,和太阳能采暖来应对建筑能耗的巨大挑战。叶片将选择性辐射冷却材料与太阳能加热材料集成。选择性辐射冷却材料(太阳反射率约97%,8-13μm波段中的选择性发射率〜0.82)结合了太阳能反射熔喷聚丙烯薄膜和太阳能透明中红外发射器聚乙烯/二氧化硅薄膜。此外,加热材料(太阳能吸收率91%,热发射率0.04)是用铜(Cu)纳米颗粒沉积的锌(Zn)膜,基于Cu-Zn电置换反应。因此,通过旋转刀片,辐射冷却的转换,太阳能供暖,和自然照明功能可以实现。在白天,多模式设备显示4°C的亚环境温度,2°C的超环境温度,冷却模式的超环境温度为5°C,发射模式,和太阳能加热模式,分别。在节能仿真的基础上,整合这些模式并在相应的气候中动态转换这些模式可以在连续的美国节省约746GJ一年(基线能耗的38%),相当于147吨二氧化碳减排量。由于其出色的多模态热管理性能,这种多模式设备将推动建筑热管理向脱碳和可持续性转变,并更加绿色。
    The cooling and heating energy consumption of buildings poses a serious threat to the energy supply and increases greenhouse gas emissions, thus adversely impacting global warming and the long-term climate change trends. Here, inspired by the structure of the louver, this work demonstrates a multimodal device that integrates radiative cooling, natural lighting, and solar heating to deal with the grand challenge of building energy consumption. The blades integrate a selective radiative cooling material with a solar heating material. The selective radiative cooling material (solar reflectance ∼97%, selective emittance ∼0.82 in the 8-13 μm waveband) combines a solar reflective melt-blown polypropylene film and a solar transparent mid-infrared emitter polyethylene/silicon dioxide film. In addition, the heating material (solar absorptance ∼91%, thermal emittance ∼0.04) is zinc (Zn) film deposited with copper (Cu) nanoparticles, based on the Cu-Zn galvanic-displacement reaction. Hence, by rotating the blades, the conversion of radiative cooling, solar heating, and natural lighting functions can be realized. In the daytime, the multimodal device displays a subambient temperature of 4 °C, a superambient temperature of 2 °C, and a superambient temperature of 5 °C for the cooling mode, transmitting mode, and solar heating mode, respectively. On the basis of the energy-savings simulation, integrating these modes and dynamic converting these modes in the corresponding climate could save ∼746 GJ in the contiguous United States for one year (38% of the baseline energy consumption), which is equivalent to ∼147 tons of carbon dioxide emission reduction. Because of its excellent multimodal thermal management performance, this multimodal device will push forward the transformative change of building thermal management toward decarbonization and sustainability and being more green.
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  • 文章类型: Journal Article
    杆菌肽(一种抗菌肽,构建了AMP)修饰的葡聚糖-MoSe2纳米片(AMP/dex-MoSe2NSs),并将其应用于低温和协同抗菌应用。dex-MoSe2的近红外(NIR)光热和过氧化物酶样活性通过静电吸附与AMP的细菌膜结合能力相结合,并实现了一种多模式抗菌方法。AMP/dex-MoSe2将H2O2转化为羟基自由基(·OH),具有较高的抗菌活性,可以避免高浓度H2O2的毒性。重要的是,NIR低温热灭菌加速了·OH的产生和AMP/dex-MoSe2的抗菌效率。由于AMP引导的对细菌膜的结合和破坏作用,与催化处理或单独的NIR光热灭菌相比,AMP/dex-MoSe2在NIR照射下对革兰氏阴性大肠杆菌显示出更好的抗菌作用。此外,AMP/dex-MoSe2的细胞毒性和溶血作用较弱,处于相对安全的范围内。这种基于AMP/dex-MoSe2纳米酶的多模式抗菌策略将为开发更安全有效的抗菌应用铺平道路。
    Bacitracin (an antimicrobial peptide, AMP)-modified dextran-MoSe2 nanosheets (AMP/dex-MoSe2 NSs) were constructed and applied for low-temperature and synergetic antibacterial applications. The near-infrared (NIR) photothermal and peroxidase-like activities of dex-MoSe2 were combined with the bacterial membrane-binding ability of AMP through electrostatic adsorption, and a multimode antibacterial method was realized. H2O2 was converted into a hydroxyl radical (·OH) by AMP/dex-MoSe2, which exhibits a higher antibacterial activity and can avoid the toxicity of a high concentration of H2O2. Importantly, the production of ·OH and the antibacterial efficiency of AMP/dex-MoSe2 were accelerated by low-temperature heat sterilization with NIR irradiation. Owing to the AMP-guided binding and destruction effect to the bacterial membrane, AMP/dex-MoSe2 shows a better antibacterial effect on Gram-negative Escherichia coli under NIR irradiation as compared to catalytic treatment or NIR photothermal sterilization alone. Furthermore, the cytotoxicity and hemolysis of AMP/dex-MoSe2 were weak and in a relatively safe range. This multimode antibacterial strategy based on the AMP/dex-MoSe2 nanozyme will pave a way for the development of more safe and efficient antibacterial applications.
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