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  • 文章类型: Journal Article
    目的:调查妇科肿瘤学家出于专业和学术目的使用社交媒体的患病率和模式。
    方法:2022年11月至12月的前瞻性在线调查针对妇科肿瘤医生(妇科肿瘤学家,外科肿瘤学家,医学肿瘤学家,放射/临床肿瘤学家,和onco-病理学家/病理学家)。调查,通过各种社交媒体平台分发,包括40个问题,以获取有关社交媒体使用的定性和定量数据。
    结果:在来自32个国家的131名受访者中,106名(80.9%)是妇科肿瘤学家,并隶属于学术机构(84.7%)。Facebook(n=110,83.9%),Twitter(n=108,82.4%),Instagram(n=100,76.3%)是使用最多的平台。受访者使用社交媒体保持更新(n=101,77.1%),网络(n=97,74%),了解会议和网络研讨会(n=97,74%),并进行学术讨论(n=84,64.1%)。在COVID-19大流行之后,100/129(77.5%)报告社交媒体使用增加。然而,只有32人(24.4%)使用它与患者联系,并对隐私以及需要单独的专业和个人账户提出了担忧。由于担心争议,四分之一的受访者不愿在社交媒体上分享他们的观点,有26人(20%)经历过网络欺凌,然而,120/130(92.3%)认为这让初级专业人士能够表达他们的观点。对区分有效内容的担忧,信息可靠性,并指出了从社交媒体中获取知识的专业观点。性别,年龄,专业,收入水平影响了社交媒体的使用模式,随着平台偏好的变化,内容参与,和目的,强调妇科肿瘤学家之间社交媒体互动的复杂景观。
    结论:虽然妇科肿瘤学家普遍使用社交媒体,特别是学术和专业发展,网络欺凌等挑战,隐私问题,对社交媒体导航进行正式培训的需求仍然存在。量身定制的培训计划和指南可以增强社交媒体在这一领域的有效和道德使用,促进专业表达和参与的安全环境。
    OBJECTIVE: To investigate the prevalence and patterns of social media use among gynecologic oncologists for professional and academic purposes.
    METHODS: A prospective online survey between November and December 2022 targeted gynecologic oncology practitioners (gynecologic oncologists, surgical oncologists, medical oncologists, radiation/clinical oncologists, and onco-pathologists/pathologists). The survey, distributed via various social media platforms, included 40 questions to capture qualitative and quantitative data on social media use.
    RESULTS: Of 131 respondents from 32 countries, 106 (80.9%) were gynecologic oncologists and affiliated with academic institutions (84.7%). Facebook (n=110, 83.9%), Twitter (n= 108, 82.4%), and Instagram (n=100, 76.3%) were the most used platforms. Respondents used social media to stay updated (n=101, 77.1%), network (n=97, 74%), learn about conferences and webinars (n=97, 74%), and engage in academic discussions (n=84, 64.1%). Following the COVID-19 pandemic, 100/129 (77.5%) reported increased social media use. However, only 32 (24.4%) used it to connect with patients, and concerns were raised about privacy and the need for separate professional and personal accounts. A quarter of respondents hesitated to share their opinions on social media due to the fear of controversy, with 26 (20%) experiencing cyberbullying, yet 120/130 (92.3%) believed it enabled junior professionals to express their views. Concerns about differentiating valid content, information reliability, and the professional perception of sourcing knowledge from social media were noted. Gender, age, specialty, and income level influenced patterns of social media use, with variations in preferences for platforms, content engagement, and purposes, highlighting a complex landscape of social media interaction among gynecologic oncologists.
    CONCLUSIONS: While the use of social media among gynecologic oncologists is prevalent, particularly for academic and professional development, challenges such as cyberbullying, privacy concerns, and the need for formal training in social media navigation persist. Tailored training programs and guidelines could enhance social media\'s effective and ethical use in this field, promoting a safe environment for professional expression and engagement.
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  • 文章类型: Letter
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  • 文章类型: Journal Article
    主要目标:描述门诊切除口腔癌后30天非计划再入院率。次要目标:评估与再入院相关的患者和治疗因素。
    回顾性,由2个三级医疗转诊中心组成的双机构队列研究,涉及接受口腔癌切除术并计划当日出院的成年患者.包括77名患者的连续样本。主要结果是手术后30天内计划外再入院或住院。在返回组和不返回组之间使用比较测试。
    在接受口腔癌门诊手术治疗的77名患者中,19人(25%)在30天内返回医院。在返回的原因中,16人(80%)与手术直接相关,4例(20%)与与手术部位无直接关系的围手术期内科并发症有关.在25例同时接受前哨淋巴结活检并进行口腔切除术的患者中,没有人因颈部相关并发症返回医院。虽然大多数患者可以安全观察并返回医院后出院,8例患者(10%)需要再次住院。没有发现回报和非回报组之间的显著差异,尽管返回组离医院的行驶距离有缩短的趋势(47.6英里vs.69.5英里,P=0.097)。
    门诊口腔切除术后计划外返回医院很普遍,主要是由于术后原发性切除部位的担忧。在选择当天出院的患者中,没有确定非计划回报风险最高的人群.
    UNASSIGNED: Primary objective: describe rates of 30-days unplanned readmission following outpatient resection of oral cavity cancer. Secondary objective: evaluate for patient and treatment factors associated with readmission.
    UNASSIGNED: Retrospective, dual-institution cohort study of 2 tertiary care referral centers involving adult patients undergoing resection of oral cavity cancer with plans for same-day discharge. Consecutive sample of 77 patients included. Primary outcome was unplanned readmission to emergency room or inpatient stay in the 30 days following surgery. Comparison testing was used between return and non-return groups.
    UNASSIGNED: Among 77 patients treated with outpatient surgery for oral cavity cancer, 19 (25%) returned to the hospital within 30 days. Among the reasons for return, 16 (80%) were directly related to surgery, and 4 (20%) were related to perioperative medical complications not directly related to a surgical site. Among the 25 patients also undergoing sentinel lymph node biopsy with their oral cavity resection, none returned to the hospital for neck-related complications. While most patients could be safely observed and discharged after return to the hospital, 8 patients (10%) required inpatient readmission. No significant differences between return and non-return groups were identified, although there was a trend toward shorter driving distance from hospital for the return group (47.6 miles vs. 69.5 miles, P = 0.097).
    UNASSIGNED: Unplanned return to the hospital following outpatient oral cavity resection is prevalent and primarily driven by postoperative primary resection site concerns. Among patients selected for same day discharge, no definite population at highest risk of unplanned return was identified.
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  • 文章类型: Journal Article
    描述休息时会厌的表型特征及其对瓣膜残留物的影响。
    视频透视研究(VFSS)来自2个喉科实践,图像J用于测量静止时的会厌解剖特征。通过MBSImp对研究进行了评估,并在吞下稀薄和泥状大丸剂后是否存在残余。进行了条件推断树分析,以分离出哪些会厌参数是存在瓣膜残留的危险因素,然后进行逻辑回归。
    大多数患者患有正常形状的会厌,其次是欧米茄形状。会厌与舌骨的平均角度约为90°。只有异常的会厌运动与细丸剂的残留风险增加相关(OR35.09,CI10.93-158.66,P<.001)。然而,在那些有正常会厌运动的人中,年龄>70岁与残留风险增加相关(OR3.98,CI1.73-9.23,P=.001).对于果泥丸,正常或欧米茄形会厌与残留相关(OR5.19,CI2.41-11.51,P<.001),通过增加会厌尖端与咽后壁的距离进一步调节了这种关系。静息会厌的其他解剖特征与残留物无关。可能影响吞咽的合并症在队列中很少见,并且与残留物无关。
    异常的会厌运动与误吸有关,在这项研究中,我们发现异常的会厌运动增加了残余的风险,年龄是残余的危险因素。会厌的静息特性似乎与异常的会厌运动或残留无关。
    UNASSIGNED: To describe the phenotypic characteristics of the epiglottis at rest and their impact on vallecular residue.
    UNASSIGNED: Videofluoroscopic studies (VFSS) were pooled from 2 Laryngology practices, and Image J was used to measure epiglottic anatomic features at rest. Studies were rated by the MBSImp and presence of vallecular residue following swallow of thin and puree boluses. A conditional inference tree analysis was performed to isolate which epiglottic parameters were risk factors for presence of vallecular reside followed by logistic regression.
    UNASSIGNED: The majority of patients had a normal shaped epiglottis, followed by omega shape. The mean angle of the epiglottis from the hyoid was approximately 90°. Only abnormal epiglottic movement was associated with increased risk of residue for thin boluses (OR 35.09, CI 10.93-158.66, P < .001). However, in those with normal epiglottic movement, age >70 years old was associated with increased risk of residue (OR 3.98, CI 1.73-9.23, P = .001). For puree boluses, a normal or omega shaped epiglottis was associated with residue (OR 5.19, CI 2.41-11.51, P < .001), and this relationship was further modulated by increased distance of the epiglottic tip from the posterior pharyngeal wall. No other anatomic features of the resting epiglottis were associated with residue. Comorbidities potentially affecting swallow were infrequent in the cohort and were not associated with residue.
    UNASSIGNED: Abnormal epiglottic movement is associated with aspiration, and in this study we find that abnormal epiglottic movement increases the risk of vallecular residue and that older age is a risk factor for residue. The resting properties of the epiglottis do not appear to be associated with abnormal epiglottic movement or residue.
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  • 文章类型: Journal Article
    对于真正的清洁污染的头部和颈部程序,文献支持≤24小时的围手术期抗生素.然而,某些耳鼻喉科手术的手术部位感染(SSI)风险较低,而抗生素预防的获益可忽略不计.这项评估的目的是描述低风险头颈部手术中抗生素的使用和对循证机构指南的遵守情况。
    这是一个单中心,接受低风险清洁污染头颈部手术的患者的回顾性队列研究,其中不需要抗生素预防,基于循证机构指南。
    在291名患者中,29%的患者在围手术期使用抗生素是不必要的.在接受抗生素治疗的患者中,76%接受术前抗生素治疗,41%接受术后抗生素治疗,中位持续时间为7天。SSI没有显著差异,死亡率,接受围手术期抗生素与未接受围手术期抗生素的住院时间。
    这些数据突出了抗生素管理干预措施的必要性以及抗生素管理团队与外科服务之间的伙伴关系。
    UNASSIGNED: For true clean-contaminated head and neck procedures, the literature supports ≤24 hours of perioperative antibiotics. However, there are certain otolaryngology procedures with low surgical site infection (SSI) risk for which there is negligible benefit from antibiotic prophylaxis. The objective of this evaluation was to describe antibiotic use and adherence to evidence-based institutional guidelines in low-risk head and neck procedures.
    UNASSIGNED: This was a single-center, retrospective cohort study of patients undergoing low-risk clean-contaminated head and neck procedures wherein antibiotic prophylaxis was not indicated, based on evidence-based institutional guidelines.
    UNASSIGNED: Among the 291 included patients, perioperative antibiotics were unnecessarily administered in 29% of patients. Among patients who received antibiotics, 76% received preoperative antibiotics and 41% received postoperative antibiotics, for a median duration of 7 days. There were no significant differences in SSIs, mortality, and length of stay for those receiving perioperative antibiotics versus those not receiving perioperative antibiotics.
    UNASSIGNED: These data highlight the need for antibiotic stewardship interventions and partnerships between antibiotic stewardship teams and surgical services.
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  • 文章类型: Journal Article
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  • 文章类型: Journal Article
    妇科癌症护理的一些最新进展改善了患者的预后。这些措施包括宫颈癌的国家筛查和疫苗接种计划以及卵巢癌的新辅助化疗。相反,这些进展累积地减少了手术训练的机会,因此需要用循证辅助手段来补充现有的训练策略.虚拟现实和增强现实等技术,如果评估和验证正确,具有支持培训的变革潜力。鉴于妇科肿瘤学外科培训的变化,我们渴望总结支持当前妇科肿瘤学培训的证据.在这次审查中,我们对Medline进行了文献检索,Google,谷歌学者,Embase和Scopus收集有关妇科肿瘤学培训现状的证据,并强调有关教授外科技能的最佳方法的现有证据。借鉴其他外科专业的经验,我们检查了尸体解剖等培训辅助手段的使用,动画和3D模型以及手术技能获取方面的模拟训练。具体来说,我们研究了妇科肿瘤学培训中培训辅助手段的使用,以及模拟培训方式背后的证据,如低保真度盒子培训师,腹腔镜培训中的虚拟和增强现实模拟。最后,我们通过研究培训课程在国际上的差异来提供背景。尽管在其他外科专业中存在模拟训练的可靠性和有效性的一些证据,我们的文献综述在妇科肿瘤中没有发现此类证据.重要的是,在将模拟训练模式纳入培训课程之前,必须进行良好的试验来确定模拟训练模式的实用性。
    Several recent advances in gynecologic cancer care have improved patient outcomes. These include national screening and vaccination programs for cervical cancer as well as neoadjuvant chemotherapy for ovarian cancer. Conversely, these advances have cumulatively reduced surgical opportunities for training creating a need to supplement existing training strategies with evidence-based adjuncts. Technologies such as virtual reality and augmented reality, if properly evaluated and validated, have transformative potential to support training. Given the changing landscape of surgical training in gynecologic oncology, we were keen to summarize the evidence underpinning current training in gynecologic oncology.In this review, we undertook a literature search of Medline, Google, Google Scholar, Embase and Scopus to gather evidence on the current state of training in gynecologic oncology and to highlight existing evidence on the best methods to teach surgical skills. Drawing from the experiences of other surgical specialties we examined the use of training adjuncts such as cadaveric dissection, animation and 3D models as well as simulation training in surgical skills acquisition. Specifically, we looked at the use of training adjuncts in gynecologic oncology training as well as the evidence behind simulation training modalities such as low fidelity box trainers, virtual and augmented reality simulation in laparoscopic training. Finally, we provided context by looking at how training curriculums varied internationally.Whereas some evidence to the reliability and validity of simulation training exists in other surgical specialties, our literature review did not find such evidence in gynecologic oncology. It is important that well conducted trials are used to ascertain the utility of simulation training modalities before integrating them into training curricula.
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  • 文章类型: Journal Article
    许多患有囊性纤维化(PwCF)的人患有慢性鼻-鼻窦炎(CRS)。CRS需要除肺部疾病以外的额外管理,并导致医疗保健资源的利用增加。Elexacaftor/tezacaftor/ivacaftor(ETI)是一种高效的调节剂疗法,已被证明可改善PwCF中的CRS。然而,ETI对鼻保健利用的影响研究不足.
    比较开始ETI治疗之前和之后PwCF的鼻科医疗利用率和程序。
    单中心,调查成人PwCF的队列研究于2023年1月进行.人口统计,临床特征,并对CF治疗相关数据进行回顾性摘录.在两个时期比较了队列的特征:ETI开始前12个月和ETI开始后12个月。如果受试者尚未完成完整的12个月的ETI,则线性外推ETI后数据。配对t检验,Wilcoxon符号等级测试,并进行回归分析。
    在126个PwCF中,98例(77.8%)接受ETI治疗,35例(27.7%)均接受ETI治疗,并同时接受鼻学服务(ETI-ENT)。开始ETI治疗后,ETI-ENT队列的鼻科临床就诊(P=.007)和获得鼻培养物的频率(P=.046)降低。进行的内窥镜鼻窦手术的数量没有显着变化(P=0.452)。除了使用ETI之外,回归分析未发现任何与利用率变化相关的因素.
    开始ETI治疗后,PwCF的鼻学医疗保健利用方面下降。需要进一步的研究来确定长期使用ETI的PwCF的鼻科医疗要求,并评估更大的PwCF对ETI的队列。
    UNASSIGNED: Many people with cystic fibrosis (PwCF) have chronic rhinosinusitis (CRS). CRS requires additional management beyond that of pulmonary disease and leads to increased utilization of healthcare resources. Elexacaftor/tezacaftor/ivacaftor (ETI) is a highly effective modulator therapy that has been shown to improve CRS in PwCF. However, the impact of ETI on rhinologic healthcare utilization is understudied.
    UNASSIGNED: To compare rates of rhinologic healthcare utilization and procedures among PwCF prior to and after initiating ETI therapy.
    UNASSIGNED: A single-center, cohort study investigating adult PwCF was performed in January 2023. Demographics, clinical characteristics, and data related to CF treatment were retrospectively abstracted. Characteristics of the cohort were compared over 2 periods: the 12-months prior to ETI initiation and the 12-months after ETI initiation. Post-ETI data were linearly extrapolated if a subject had not yet completed the full 12 months of ETI. Paired t-testing, Wilcoxon signed rank testing, and regression analysis were performed.
    UNASSIGNED: Of 126 PwCF, 98 (77.8%) were on ETI therapy and 35 (27.7%) were both on ETI and concurrently followed by the rhinology service (ETI-ENT). Rhinology clinic visits (P = .007) and frequency of obtaining nasal cultures (P = .046) decreased for the ETI-ENT cohort after initiating ETI treatment. There were no significant changes in the number of endoscopic sinus surgeries (P = .452) performed. Beyond ETI use, regression analysis did not identify any factors associated with changes in utilization.
    UNASSIGNED: Aspects of rhinology healthcare utilization by PwCF decreased after initiation of ETI therapy. Additional studies are needed to determine rhinologic healthcare requirements for PwCF who remain on ETI for the long-term and to evaluate larger cohorts of PwCF on ETI.
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  • 文章类型: Case Reports
    主要目的是描述一种情况,其中使用类固醇洗脱植入物来帮助预防因声门下狭窄而接受双期喉气管重建(dsLTR)的患者的术后肉芽和再狭窄。
    该病例介绍了一名3岁的女性,该女性接受了dsLTR并进行了前软骨移植和后矢状分裂,以治疗声门下狭窄。在dsLTR时放置硅酮支架。支架移除后,每隔4~5周进行一次直接喉镜和支气管镜检查(DLB).这些访问显示了大量的声门上和声门水肿,和移植物近端的肉芽组织导致气道阻塞和再狭窄。用CO2激光切除治疗了两次,球囊扩张,和曲安奈德注射液.在使用这些方式的第三种治疗中,我们插入了糠酸莫米松植入物作为辅助治疗.植入物被插入以偏侧声带,防止织带,并延伸到声门下的狭窄区域,以防止肉芽和再狭窄。在第四次就诊时重复这些相同的治疗,将另一个较小尺寸的糠酸莫米松植入物放置在相同位置。
    自使用类固醇洗脱植入物治疗以来,对DLB的发现显示出持续的肉芽组织仅限于气管造口部位。CO2激光治疗,球囊扩张,曲安奈德注射仍在继续,偶尔在外部造口部位使用硝酸银烧灼器。没有任何明显的水肿证据,造粒,或声门或声门下狭窄,需要另一个类固醇洗脱植入物。
    类固醇洗脱植入物似乎是一种安全有效的辅助治疗方法,用于气管造口术后接受dsLTR的儿科患者的常规监测。它们可以帮助对抗在一些dsLTR患者中看到的肉芽形成和再狭窄。
    UNASSIGNED: The primary objective is to describe a case in which a steroid-eluting implant was utilized to help prevent postoperative granulation and restenosis in a patient who underwent double-stage laryngotracheal reconstruction (dsLTR) for subglottic stenosis.
    UNASSIGNED: This case presents a 3-year-old female who underwent dsLTR with anterior cartilage graft placement and posterior sagittal split for subglottic stenosis. A silicone stent was placed at the time of the dsLTR. After stent removal, direct laryngoscopy and bronchoscopy (DLB) was performed at 4 to 5 week intervals. These visits revealed a significant amount of supraglottic and glottic edema, and granulation tissue at the proximal aspect of the graft contributing to airway obstruction and restenosis. This was treated twice with CO2 laser excision, balloon dilation, and triamcinolone injection. On the third treatment with these modalities, a mometasone furoate implant was inserted as an adjunctive therapy. The implant was inserted to lateralize the vocal folds, prevent webbing, and to extend to the narrowed area within the subglottis to prevent granulation and restenosis. These same treatments were repeated at the fourth visit with another mometasone furoate implant of a smaller size placed in the same location.
    UNASSIGNED: Findings on DLB since treatment with the steroid-eluting implants have shown persistent granulation tissue limited to the tracheostomy stoma site. Treatments with CO2 laser, balloon dilation, and triamcinolone injection have continued, with occasional use of silver nitrate cautery at the external stoma site. There has not been any significant evidence of edema, granulation, or stenosis in the glottis or subglottis to require another steroid-eluting implant.
    UNASSIGNED: Steroid-eluting implants appear to be a safe and effective adjunctive therapy in the routine surveillance of pediatric patients with a tracheostomy who have undergone dsLTR. They may help combat granulation formation and restenosis seen in some dsLTR patients.
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  • 文章类型: Journal Article
    持续鼓膜穿孔是压力平衡(PE)管插入的已知并发症。传导性听力损失和耳漏可能需要对这些穿孔进行手术修复。长期放置鼓膜置管会增加这些并发症的风险。心面综合征(VCFS)患者通常需要长时间放置PE管,并且被认为在放置PE管后需要额外的耳科干预的风险更高。迄今为止,在VCFS患者中,没有确定需要鼓膜成形术或鼓室成形术的PE管后并发症的发生率.
    在2000年至2020年期间,在一家大型儿童医院进行了回顾性病例回顾,包括所有VCFS患者。所需的PE管插入次数和进行的额外耳科干预是评估的主要终点。
    在212名VCFS患者中,66例(31%)接受了PE管放置。在这些孩子中,46(70%)需要2套或更多的PE管。除PE管插入外,共有53例患者(80.3%)无需耳科干预。在需要额外耳科手术的13例患者(19.7%)中,6人(9.5%)接受了鼓膜成形术,9例(13.6%)需要鼓室成形术。鼓室成形术无显著性差异(P>1),鼓膜成形术(P>1),或其他手术干预率(P=.7464)VCFS患者的任何类型的left裂与那些解剖正常的腭。
    这项工作表明,大多数需要插管的VCFS患者,至少需要2套PE管,需要进一步进行耳科手术的PE管后并发症的发生率比该机构确定的发生率高一个数量级。在VCFS患者中进行PE管放置的咨询可能需要进行有关并发症风险大幅增加的具体对话,并努力建立对手术结果的适当期望,而无论腭状态如何。
    UNASSIGNED: Persistent tympanic membrane perforation is a known complication of pressure-equalizing (PE) tube insertion. Conductive hearing loss and otorrhea can necessitate surgical repair of these perforations. Long-term tympanostomy tube placement can increase the risk of these complications. Patients with velocardiofacial syndrome (VCFS) typically require prolonged PE tube placement and are thought to have higher risk of requiring additional otologic interventions after PE tube placement. To date, no work has established rates of post-PE tube complications requiring myringoplasty or tympanoplasty in patients with VCFS.
    UNASSIGNED: A retrospective case review including all patients with VCFS at a single large children\'s hospital between the years 2000 and 2020 was performed. Number of PE tube insertions required and additional otologic interventions performed were the primary endpoints assessed.
    UNASSIGNED: Of 212 total patients with VCFS, 66 (31%) underwent PE tube placement. Of these children, 46 (70%) required 2 or more sets of PE tubes. A total of 53 patients (80.3%) required no otologic interventions apart from PE tube insertions. Of the 13 patients (19.7%) requiring additional otologic surgery, 6 (9.5%) underwent myringoplasty, and 9 patients (13.6%) required tympanoplasty. There was no significant difference in tympanoplasty (P > 1), myringoplasty (P > 1), or other surgical intervention rates (P = .7464) between VCFS patients with any type of cleft palate versus those with anatomically normal palates.
    UNASSIGNED: This work suggests that most VCFS patients that require tubes, require at least 2 sets of PE tubes, and that the rate of post-PE tube complications requiring further otologic surgery is an order of magnitude higher than the rate established at this institution. Counseling for PE tube placement in VCFS patients may require specific dialogue regarding the substantially increased risk of complications and effort to build appropriate expectations for surgical outcomes regardless of palatal status.
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