Minimally-invasive

微创
  • 文章类型: Journal Article
    背景:近年来,无骨水泥短柄全髋关节置换术(THA)的适应症已经扩大到老年患者,因为他们也可能受益于短弯曲植入物设计的优势.因此,本研究旨在评估老年患者(≥75岁)与年轻对照组(≤60岁)的临床和放射学结局.
    方法:对2014年至2017年间进行的316个THA的回顾性队列进行了前瞻性检查。在所有患者中,无水泥,弯曲的短杆和压合杯(Fitmore®杆;Allofit®/-S杯;ZimmerBiomet,华沙,IN,美国)通过微创前外侧入路植入。评估临床和放射学结果以及并发症和翻修率。
    结果:总计,已纳入292例患者的并发症和修订分析(Ø随访:4.5年)和208例患者的临床和放射学结果(Ø随访:4.4年)。老年患者并发症发生率显著增加(13.7%vs.5.8%,p=0.023),而修订率增加无统计学意义(5.2%vs.2.2%,p=0.169)。老年患者的假体周围骨折发生率明显较高(5.2%vs.0.7%;p=0.026)。两组在Harris髋关节评分(93.7vs.91.9;p=0.224),牛津髋关节得分(44.5vs.43.7;p=0.350),被遗忘的联合得分(81.7vs.81.5;p=0.952)和WOMAC(7.4与9.3;p=0.334)。
    结论:在75岁以上的患者中,与60岁以下的年轻患者相比,无水泥短柄全髋关节置换术显示出相当的临床和放射学结果。然而,无骨水泥短裤茎THA显示75岁以上老年患者的总体并发症和假体周围骨折发生率增加。75岁以上的患者应考虑股骨组件的胶结固定。
    方法:III病例对照研究。
    背景:由于ICMJE标准,无需试验注册的观察性研究。
    BACKGROUND: In recent years, the indication for cementless short stem total hip arthroplasty (THA) has been widened to elderly patients as they might profit by the advantages of the short-curved implant design as well. Therefore, this study was conducted to evaluate the clinical and radiological outcome of a cementless short stem in elderly patients (≥ 75 years) compared to a young control group (≤ 60 years).
    METHODS: A retrospective cohort of 316 THAs performed between 2014 and 2017 was prospectively examined. In all patients a cementless, curved short stem and press-fit cup (Fitmore® stem; Allofit®/-S cup; both ZimmerBiomet, Warsaw, IN, USA) were implanted via a minimally-invasive anterolateral approach. Clinical and radiological outcome as well as rate of complications and revision were assessed.
    RESULTS: In total, 292 patients have been included for analysis of complications and revisions (Øfollow-up: 4.5 years) and 208 patients for clinical and radiological outcome (Øfollow-up: 4.4 years). Complication rate was significantly increased in elderly patients (13.7% vs. 5.8%, p = 0.023), while the revision rate was increased without statistical significance (5.2% vs. 2.2%, p = 0.169). Periprosthetic fractures occurred significantly higher in the elderly patients (5.2% vs. 0.7%; p = 0.026). Both groups showed a comparable clinical outcome in the Harris Hip Score (93.7 vs. 91.9; p = 0.224), Oxford Hip Score (44.5 vs. 43.7; p = 0.350), Forgotten Joint Score (81.7 vs. 81.5; p = 0.952) and WOMAC (7.4 vs. 9.3; p = 0.334).
    CONCLUSIONS: Cementless short stem total hip arthroplasty shows a comparable clinical and radiological outcome in patients over 75 years of age compared to younger patients under 60 years of age. However, cementless shorts stem THA shows an increased rate of overall complications and periprosthetic fractures in elderly patients over 75 years of age. Cemented fixation of the femoral component should be considered in patients over 75 years of age.
    METHODS: III Case-controlled study.
    BACKGROUND: Observational study without need for trial registration due to ICMJE criteria.
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  • 文章类型: Journal Article
    目的:外侧椎间融合术(LIF)是一种越来越流行的微创脊柱手术。本研究确定了LIF文献中的显着趋势,并对引用最多的前100篇文章的文献计量学方面进行了详细的回顾。
    方法:文章从WebofScience数据库查询。纳入标准包括同行评审的文章,全文可用性,LIF焦点。包括共同作者映射和书目耦合在内的网络分析得到了趋势分析的补充,以确定突出的贡献者和主题。使用VOSviewer和Bibliometrix(RStudio)进行分析。
    结果:自1998年以来,LIF出版物和引文数量迅速增加。主要期刊是Spine(n=24),神经外科脊柱杂志(n=22),和欧洲脊柱杂志(n=12)。NuVasive资助的出版物最多(n=17),其次是DePuySynthes脊柱(n=4)。美国是最具代表性的国家(n=81);然而,趋势分析表明,国际贡献稳步增长。最多产的作者是J.S.Uribe(n=16),紧随其后的是E.Dakwar和L.Pimenta(n=8)。最常见的关键词,“并发症”(n=34),“手术”(n=30),和“结果”(n=24),展示了一个以病人为中心的主题。
    结论:该文献计量分析提供了对LIF在过去二十年中的演变和趋势的深入见解。确定的趋势和主题表明了创新,协作,以及这个子场以患者为中心的特征。未来的研究人员可以以此为基础,在设计调查时了解LIF研究的过去和现在状态。
    OBJECTIVE: Lateral interbody fusion (LIF) is an increasingly popular minimally-invasive spine procedure. This study identifies notable trends in LIF literature and provides a detailed review of the bibliometric aspects of the top 100 most-cited articles.
    METHODS: Articles were queried from the Web of Science database. Inclusion criteria consisted of peer-reviewed articles, full-text availability, and LIF focus. Network analysis including co-authorship mapping and bibliographic coupling were complemented by trend analysis to determine prominent contributors and themes. Analyses were conducted using VOSviewer and Bibliometrix (RStudio).
    RESULTS: There has been a rapid increase in LIF publication and citation count since 1998. Leading journals were Spine (n = 24), Journal of Neurosurgery Spine (n = 22), and European Spine Journal (n = 12). NuVasive funded the most publications (n = 17), followed by DePuy Synthes Spine (n = 4). The United States was the most represented country (n = 81); however, trend analysis suggests a steadily growing international contribution. The most prolific author was J.S. Uribe (n = 16), followed by a tie in second place by E. Dakwar and L. Pimenta (n = 8). The most frequent keywords, \"complication\" (n = 34), \"surgery\" (n = 30), and \"outcomes\" (n = 24), demonstrated a patient-centric theme.
    CONCLUSIONS: This bibliometric analysis provides in-depth insights into the evolution and trends of LIF over the last two decades. The trends and themes identified demonstrate the innovative, collaborative, and patient-focused characteristics of this subfield. Future researchers can use this as a foundation for understanding the past and present state of LIF research while designing investigations.
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  • 文章类型: Journal Article
    在过去的几十年中,诊断监测和技术创新的增加大大增加了甲状腺切除术的数量。虽然甲状腺切除术仍然是治疗的第一线,其他微创和保守的选择应用在非常有选择的情况下已经提出。这篇综述的目的是说明这些技术的优缺点。
    暂无摘要。
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  • 文章类型: Journal Article
    股骨头缺血性坏死是一种可导致股骨头塌陷的衰弱状态。核心减压辅助细胞疗法,如骨髓抽取液浓缩物,延缓疾病进展,改善预后。然而,文献中不一致的结果可能是由于手术技术的局限性和定位坏死病变的困难.这里,我们提出了一种手术技术,该技术利用基于计算机断层扫描的三维建模和仪器跟踪来将治疗引导到病变中心.该方法使到达病变的尝试次数最小化,并确认器械在病变内的三维定位。我们的技术可以改善髓芯减压和辅助治疗的结果,并预防或延迟股骨头缺血性坏死患者的髋关节塌陷。
    Avascular necrosis of the femoral head is a debilitating condition that can lead to femoral head collapse. Core decompression with adjuvant cellular therapies, such as bone marrow aspirate concentrate, delays disease progression and improves outcomes. However, inconsistent results in the literature may be due to limitations in surgical technique and difficulty in targeting the necrotic lesions. Here, we present a surgical technique utilizing computed tomography-based three-dimensional modeling and instrument tracking to guide the therapy to the center of the lesion. This method minimizes the number of attempts to reach the lesion and confirms the three-dimensional positioning of the instrumentation within the lesion. Our technique may improve the outcomes of core decompression and adjuvant therapy and prevent or delay hip collapse in patients with femoral head avascular necrosis.
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  • 文章类型: Journal Article
    机器人辅助腹侧疝修补术(RVHR)已成为开放式腹侧疝修补术的可行替代方法,显示出更少的术后并发症并令人满意的短期结果。然而,在目前的文献中,长期结果很少。
    从2018年6月至2023年2月接受机器人辅助腹侧疝手术的所有连续患者均包括在内。对患者记录进行回顾性审查以确定适应症,需要转换,停留时间(LOS)术后并发症,和术后疼痛。此外,长期(>24个月)结果(复发,慢性疼痛,和审美满意度)通过电话问卷进行评估。
    总共,177例患者接受了机器人辅助的腹侧疝修补术。手术指征为切口疝(N=109)和原发性疝(N=68),其中腹直肌舒张124例。138例患者进行了经腹肌后脐假体(TARUP)。在20例(11%)和9例(5%)中进行了机器人腹横肌释放(TAR)和扩展的完全腹膜外修复(eTEP)。分别。TARUP的中位LOS为2天,TAR的中位LOS为3.5天。22例患者发生轻微并发症(16TARUP,5TAR,1eTEP)。术后第一天的平均疼痛评分为1.8/10。通过单变量和多变量分析无法确定发病的危险因素。四名(2%)患者出现疝复发。2例(1%)报告了慢性疼痛。7名(4%)患者有审美抱怨。
    机器人辅助腹侧疝修补术是一种安全的手术,术后疼痛低,LOS短。包括复发和慢性疼痛在内的长期结果令人满意。
    UNASSIGNED: Robot-assisted ventral hernia repair (RVHR) has become a feasible alternative for open ventral hernia repair showing fewer postoperative complications and satisfying short-term results. However, long-term results are scarce in current literature.
    UNASSIGNED: All consecutive patients who underwent robot-assisted surgery for ventral hernias from June 2018 until February 2023 were included. Patient records were retrospectively reviewed for indication, need for conversion, length of stay (LOS), postoperative complications, and postoperative pain.In addition, long-term (>24 months) results (recurrence, chronic pain, and esthetic satisfaction) were assessed by phone questionnaire.
    UNASSIGNED: In total, 177 patients underwent a robot-assisted ventral hernia repair. Indication for surgery was incisional hernia (N = 109) and primary hernia (N = 68), including 124 cases with abdominal rectus diastasis. A TransAbdominal Retromuscular Umbilical Prosthesis (TARUP) was performed in 138 patients. Robotic Transversus Abdominis Release (TAR) and Extended Totally Extraperitoneal Repair (eTEP) were performed in 20 (11%) and 9 (5%) cases, respectively.Median LOS was 2 days for TARUP and 3.5 days for TAR. Minor complications occurred in 22 patients (16 TARUP, 5 TAR, 1 eTEP). The average pain score on the first postoperative day was 1.8/10. No risk factors for morbidity could be identified by uni- and multivariable analysis.Hernia recurrence developed in four (2%) patients. Chronic pain was reported in two (1%) cases. Seven (4%) patients had esthetic complaints.
    UNASSIGNED: Robot-assisted ventral hernia repair is a safe procedure with low postoperative pain and short LOS. Long-term results including recurrence and chronic pain are satisfying.
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  • 文章类型: Journal Article
    小儿器官移植领域近几十年来有了显著的发展,介入放射学(IR)在管理移植前和移植后并发症中起着至关重要的作用。与成年人相比,儿科移植患者面临着独特的挑战,包括供体-受体大小不匹配,和一个成长中的孩子改变生理机能的并发症。介入放射科医师在小儿肾脏和肝脏移植中起主要作用。IR干预在儿童移植前的早期开始,通过活检等诊断程序,血管造影,和胆管造影。这些程序对于了解器官衰竭的病因和确定潜在的移植候选者至关重要。微创治疗程序可以作为移植的桥梁,并且可以包括优化血液透析的血管通路。经颈静脉肝内门体分流术(TIPS)创建,和肿瘤栓塞或消融。移植后,图像引导活检,用于监测移植物排斥反应和治疗血管或管腔狭窄,假性动脉瘤,吻合口漏可以维持移植器官的功能和寿命。必须仔细考虑患者的大小和不断发展的解剖结构,辐射暴露,以及儿科患者需要更深入的镇静。尽管面临这些挑战,IR在儿科移植护理中的整合已被证明是有益的,提供微创手术的替代方案,更快的恢复时间,和改善的结果。
    The field of pediatric organ transplantation has grown significantly in recent decades, with interventional radiology (IR) playing an essential role in managing pre and post-transplant complications. Pediatric transplant patients face unique challenges compared to adults, including donor-recipient size mismatch, and complications of a growing child with changing physiology. Interventional radiologists play a major role in pediatric renal and liver transplant. IR interventions begin early in the child\'s pretransplant journey, with diagnostic procedures such as biopsies, angiograms, and cholangiograms. These procedures are essential for understanding the etiology of organ failure and identifying potential transplant candidates. Minimally invasive therapeutic procedures may serve as bridges to transplant and may include vascular access optimization for hemodialysis, transjugular intrahepatic portosystemic shunts (TIPS) creation, and tumor embolization or ablation. After transplant, image-guided biopsies for the surveillance of graft rejection and treatment of vascular or luminal stenoses, pseudoaneurysms, and anastomotic leaks can maintain the function and longevity of the transplant organ. Careful consideration must be given to patient size and evolving anatomy, radiation exposure, and the need for deeper sedation for pediatric patients. Despite these challenges, the integration of IR in pediatric transplant care has proven beneficial, offering minimally invasive alternatives to surgery, faster recovery times, and improved outcomes.
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  • 文章类型: Journal Article
    背景:机器人方法在微创肝脏手术(MILS)中的优势仍在争论中。这项研究比较了倾向评分匹配队列中腹腔镜(LLR)和机器人(RLR)肝切除术之间的短期结果。
    方法:回顾性分析了两个肝脏外科单位的微创肝切除数据。倾向评分匹配分析(1:1比例)确定了两组具有相似特征的患者。然后比较术中和术后结果。MILS的难度基于IWATE标准。
    结果:2014年1月至2021年12月期间,共有两百六十九名患者接受了MILS(LLR=192;RLR=77)。倾向评分匹配确定148例(LLR=74;RLR=74),由代偿性肝硬化患者(100%)接受非解剖切除IWATE1-2级(90.5%)的孤立性肿瘤直径<5cm(93.2%)。在这样的病人中,RLRs的手术时间较短(227vs.250分钟,p=0.002),Pringle的累积时间较短(12与28分钟,p<0.0001),减少失血(137vs.209cc,p=0.006)与LLR.转化率为nihil(两组)。在RLR与LLR相比,R0率(93与96%,p>0.71)和主要发病率(4.1vs.5.4%,p>0.999)相似,无术后死亡率。机器人组的住院时间较短(6.2vs.6.6,p=0.0001)。
    结论:本研究支持RLR相对于LLR的非劣效性。在代偿性肝硬化患者中,对于<5cm的孤立性结节进行了低至中等难度的切除,RLR更快,尽管肝门夹紧时间较短,但失血量较少,与LLR相比,需要更短的住院时间。
    The advantages of the robotic approach in minimally invasive liver surgery (MILS) are still debated. This study compares the short-term outcomes between laparoscopic (LLR) and robotic (RLR) liver resections in propensity score matched cohorts.
    Data regarding minimally invasive liver resections in two liver surgery units were retrospectively reviewed. A propensity score matched analysis (1:1 ratio) identified two groups of patients with similar characteristics. Intra- and post-operative outcomes were then compared. The difficulty of MILS was based on the IWATE criteria.
    Two hundred sixty-nine patients underwent MILS between January 2014 and December 2021 (LLR = 192; RLR = 77). Propensity score matching identified 148 cases (LLR = 74; RLR = 74) consisting of compensated cirrhotic patients (100%) underwent non-anatomic resection of IWATE 1-2 class (90.5%) for a solitary tumor < 5 cm in diameter (93.2%). In such patients, RLRs had shorter operative time (227 vs. 250 min, p = 0.002), shorter Pringle\'s cumulative time (12 vs. 28 min, p < 0.0001), and less blood loss (137 vs. 209 cc, p = 0.006) vs. LLRs. Conversion rate was nihil (both groups). In RLRs compared to LLRs, R0 rate (93 vs. 96%, p > 0.71) and major morbidity (4.1 vs. 5.4%, p > 0.999) were similar, without post-operative mortality. Hospital stay was shorter in the robotic group (6.2 vs. 6.6, p = 0.0001).
    This study supports the non-inferiority of RLR over LLR. In compensated cirrhotic patients underwent resection of low-to-intermediate difficulty for a solitary nodule < 5 cm, RLR was faster, with less blood loss despite the shorter hilar clamping, and required shorter hospitalization compared to LLR.
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  • 文章类型: Journal Article
    仔细的术前计划是微创根治性顺行模块化胰脾切除术(MI-RAMPS)的关键。这项回顾性研究旨在显示肿瘤右缘与脾系膜汇合(d-SMC)或胃十二指肠动脉(d-GDA)的左缘之间的计算机断层扫描距离的实际意义。在2011年1月至2022年6月之间,对胰腺癌或恶性导管内粘液性乳头状肿瘤进行了48例微创RAMPS。两个程序转换为开放手术(4.3%)。平均肿瘤大小为31.1±14.7mm。平均d-SMC为21.5±18.5mm。平均d-GDA为41.2±23.2mm。10例患者(20.8%)进行了静脉切除术,在19例手术中(43.1%)无法通过内窥镜吻合器分割胰颈。需要静脉切除的病人,平均d-SMC为10mm(1.5-15.5),无静脉切除者为18mm(10-37)(p=0.01).进行静脉切除的d-SMC的截止值为17mm(AUC0.75)。当无法使用内窥镜吻合器分割胰腺时,平均d-GDA为26mm(19-39)mm,和46毫米(30-65)时,胰腺的颈部被缝合(p=0.01)。d-GDA在胰腺颈部后安全通过内窥镜吻合器的截止值为43mm(AUC0.75)。计算机断层扫描d-SMC和d-GDA是计划MI-RAMPS时的关键测量值。
    Careful preoperative planning is key in minimally invasive radical antegrade modular pancreatosplenectomy (MI-RAMPS). This retrospective study aims to show the practical implications of computed tomography distance between the right margin of the tumor and either the left margin of the spleno-mesenteric confluence (d-SMC) or the gastroduodenal artery (d-GDA). Between January 2011 and June 2022, 48 minimally invasive RAMPS were performed for either pancreatic cancer or malignant intraductal mucinous papillary neoplasms. Two procedures were converted to open surgery (4.3%). Mean tumor size was 31.1 ± 14.7 mm. Mean d-SMC was 21.5 ± 18.5 mm. Mean d-GDA was 41.2 ± 23.2 mm. A vein resection was performed in 10 patients (20.8%) and the pancreatic neck could not be divided by an endoscopic stapler in 19 operations (43.1%). In patients requiring a vein resection, mean d-SMC was 10 mm (1.5-15.5) compared to 18 mm (10-37) in those without vein resection (p = 0.01). The cut-off of d-SMC to perform a vein resection was 17 mm (AUC 0.75). Mean d-GDA was 26 mm (19-39) mm when an endoscopic stapler could not be used to divide the pancreas, and 46 mm (30-65) when the neck of the pancreas was stapled (p = 0.01). The cut-off of d-GDA to safely pass an endoscopic stapler behind the neck of the pancreas was 43 mm (AUC 0.75). Computed tomography d-SMC and d-GDA are key measurements when planning for MI-RAMPS.
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  • 文章类型: Journal Article
    分享我们为在2019年冠状病毒病(COVID-19)大流行期间在门诊手术中心(ASC)遭受非致命机动车事故(MVA)的患者进行微创颈椎和腰椎手术的手术经验。
    颈椎前路椎间盘切除融合术(ACDF),前路腰椎椎间融合术(ALIF),微创椎板切开术和椎间盘切除术(MILD),对精心选择的患者进行经皮内镜激光辅助椎间盘切除术(PELD)和经皮椎体后凸成形术(PK)。
    从2020年1月至2021年12月,我们小组对153例患者进行了164例病例,涉及249个椎间盘(IVD)水平。其中,116例(70.73%)中114例(74.51%)为宫颈,腰椎48例(29.27%)(其中PK8例)。八名患者在一次麻醉(SAS)中同时接受了颈椎和腰椎手术,并于同一天出院。106例ACDF(92.17%)处于C4-C5和C5-C6水平,其中包括146个(76.04%)IVD。在40例非PK腰椎病例中,38(95.0%)在L4至S1腰椎水平。其中6例(15.0%)涉及2个腰椎水平。相比之下,8个椎体后凸畸形中有6个(75.0%)涉及下胸/上腰椎柱(T11至L2),2个位于下腰椎L4水平。
    在COVID-19大流行期间,我们成功且安全地在ASC中进行了各种颈椎和腰椎手术,所有患者均实现了当天出院(SDD)。在非致命MVA中,中下颈椎(C4至C6)和下腰椎(L4至S1)的IVD是受影响最大的水平。
    UNASSIGNED: To share our surgical experiences of minimally invasive cervical and lumbar procedures for patients who suffered from non-fatal motor vehicle accidents (MVAs) in the ambulatory surgery centers (ASCs) during the coronavirus disease 2019 (COVID-19) pandemic.
    UNASSIGNED: Anterior cervical discectomy and fusion (ACDF), anterior lumbar interbody fusion (ALIF), minimally invasive laminotomy and discectomy (MILD), percutaneous endoscopic laser-assisted discectomy (PELD) and percutaneous kyphoplasty (PK) were performed on carefully selected patients.
    UNASSIGNED: From January 2020 to December 2021, our group performed 164 cases on 153 patients involving 249 intervertebral disc (IVD) levels. Of these, 116 cases (70.73%) on 114 patients (74.51%) were cervical, 48 cases (29.27%) were lumbar (including 8 PK cases). Eight patients had both cervical and lumbar procedures in a single anesthetic session (SAS) and were discharged on the same day. One hundred and six ACDF cases (92.17%) were at the C4-C5 and C5-C6 levels, which comprised of 146 (76.04%) IVDs. Of the 40 non-PK lumbar cases, 38 (95.0%) were at L4 to S1 lumbar levels. Six of these cases (15.0%) involved 2 lumbar levels. In contrast, 6 out of 8 kyphoplasties (75.0%) involved lower thoracic/higher lumbar vertebral columns (T11 to L2) and 2 were at the lower lumbar L4 level.
    UNASSIGNED: We successfully and safely performed various cervical and lumbar spine surgeries in the ASCs amid COVID-19 pandemic and all patients achieved the same-day discharge (SDD). In the non-fatal MVAs, mid-lower cervical (C4 to C6) and lower lumbar (L4 to S1) IVDs were the most affected levels.
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  • 文章类型: Journal Article
    背景:机器人手术和ERAS协议护理都是突出的发展,并已成为全球趋势。然而,机器人手术和ERAS护理联合应用于结直肠切除术的效果和学习曲线尚未得到很好的验证.本研究旨在介绍我们的实际经验,并建立在结直肠切除术的微创手术中实施ERAS计划所需的学习曲线。同时还评估了机器人技术的发展对ERAS结果的影响。
    方法:共有155名患者接受了选择性,微创手术,包括腹腔镜手术和机器人手术,本回顾性分析包括2019年6月至2021年9月期间的ERAS护理.患者按时间顺序分为五组(每五分之一31例)。患者人口统计学,肿瘤特征,围手术期数据,ERAS合规性,和手术结果都在五分位数之间进行了比较。根据ERAS顺应性和最佳回收率评估学习曲线,由没有重大并发症组成,术后住院时间(LOS)不超过5天,30天内不能再入院.使用多变量逻辑回归模型评估与术后LOS相关的因素。
    结果:在人口统计学和肿瘤特征参数方面,总体或五分之一组之间没有统计学上的显着差异。共有79名患者(51%)接受了机器人手术,机器人组的比例按时间顺序从第一个五分之一的零上升到第五个五分之一的90.3%(p<0.001)。总体ERAS方案的中位符合率为83.3%,第一五分之一为72.2%,第二至第五五分之一为83.3%(p<0.001)。共有85例患者接受了手术后的最佳恢复,第一个五分之一中的四名患者,第二个五分之一的11名患者,分别为第3-5个五分位数的21、24、25名患者(p<0.001)。术后LOS从早期组到晚期组有显著改善(p<0.001)。此外,手术结果包括手术后24小时内首次口服,首次大便时间和静脉输液的提前终止显示,五分位患者的首次大便时间有显著改善.多变量逻辑回归模型表明,机器人手术在术后LOS时优于腹腔镜手术(比值比=5.029,95%置信区间[CI]=1.321至19.142;p=0.018)。
    结论:我们的经验表明,在微创结直肠手术中有效实施ERAS计划需要31名患者达到更高的依从性,并且需要更多的病例达到成熟阶段以实现最佳恢复。我们认为,开发机器人平台不会影响ERAS实施的学习曲线。此外,对于接受结直肠切除术的患者,通过ERAS护理和机器人手术的组合,对手术的术后长度有有益的影响.
    BACKGROUND: Robotic surgery and ERAS protocol care are both prominent developments and have each become global trends. However, the effects and learning curves of combining robotic surgery and ERAS care in colorectal resection have not yet been well validated. This study aimed to present our real-world experience and establish the learning curves necessary for the implementation of an ERAS program in minimally-invasive surgery for colorectal resection, while also evaluating the impact that the development of the robotic technique has on ERAS outcomes.
    METHODS: A total of 155 patients who received elective, minimally-invasive surgery, including laparoscopic and robotic surgery for colorectal resection, with ERAS care during the period June 2019 to September 2021 were included in this retrospective analysis. Patients were divided chronologically into five groups (31 cases per quintile). Patient demographics, tumor characteristics, perioperative data, ERAS compliance, and surgical outcomes were all compared among the quintiles. Learning curves were evaluated based on ERAS compliance and optimal recovery, which are composed of an absence of major complications, postoperative length of stay (LOS) of no more than five days, and no readmission within 30 days. A multivariable logistic regression model was used to assess factors associated with postoperative LOS.
    RESULTS: There were no statistically significant differences seen overall or between the quintile groups in regards to demographic and tumor characteristic parameters. A total of 79 patients (51%) received robotic surgery, with the ratio of robotic groups rising chronologically from zero in the first quintile to 90.3% in the fifth quintile (p < 0.001). The median compliance rate of total ERAS protocol was 83.3% overall, 72.2% in the first quintile and 83.3% in the 2nd-5th quintiles (p < 0.001). A total of 85 patients underwent optimal recovery after surgery, four patients in the first quintile, 11 patients in the second quintile, and 21, 24, 25 patients in the 3rd-5th quintiles respectively (p < 0.001). There were significant improvements from early to later groups upon postoperative LOS (p < 0.001). In addition, the surgical outcomes including first oral intake within 24 hours after surgery, time to first stool and early termination of intravenous fluid administration showed significant improvement among the quintiles. A multivariable logistic regression model demonstrated that robotic surgery was superior to laparoscopic surgery upon postoperative LOS (odds ratio = 5.029, 95% confidence interval [CI] = 1.321 to 19.142; p = 0.018).
    CONCLUSIONS: Our experience demonstrated that an effective implementation of the ERAS program in minimally-invasive colorectal surgery requires 31 patients to accomplish the higher compliance and requires more cases to reach the maturation phase for optimal recovery. We believe that developing a robotic platform would have no impact on the learning curve of ERAS implementation. Moreover, there is a beneficial effect on the postoperative length of surgery provided through the combination of ERAS care and robotic surgery for patients undergoing colorectal resection.
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