Minimal-invasive

微创
  • 文章类型: Journal Article
    髋臼骨折是创伤学中最具挑战性的损伤之一。复杂的解剖结构通常需要广泛的手术方法,以免对周围的神经血管结构造成医源性损伤。作为一种可行的选择,近年来出现了微创内镜技术。本文报道了专门为微创髋臼手术设计的新型外皮上钢板的不同耦合机制的可行性。
    共有34名参与者参与了本研究,他们的关节镜和手术经验不同。腹腔镜模型用于通过失败的尝试次数比较四种不同的耦合机制,钢板固定所需的时间,手术经验以及学习成功对每个个体耦合机制的影响。此外,通过问卷评估每种机制的可行性.
    结果表明,采用开槽和压力滑动耦合机构的板减少了失败的尝试,并减少了试验时间,特别是在对比唯一的滑动机构。此外,我们的研究显示,熟练掌握内镜操作对结局有显著影响.值得注意的是,参与者的主观评价表明,压力底座和压力滑动底板设计是最支持和可行的设计。
    总之,本研究首次评估了微创手术的不同钢板和联轴器设计,表明具有开槽和压力滑动机构的板具有优越的可行性。
    UNASSIGNED: Acetabular fractures are among the most challenging injuries in traumatology. The complex anatomy usually requires extensive surgical approaches baring the risk for iatrogenic damage to surrounding neurovascular structures. As a viable alternative, minimally invasive endoscopic techniques have emerged during the recent years. This paper reports on the feasibility of different coupling mechanisms for a novel suprapectineal plate especially designed for minimally invasive acetabular surgery.
    UNASSIGNED: A total number of 34 participants contributed to the present study, who differed in their arthroscopic and surgical experience. A laparoscopic model was used to compare four different coupling mechanisms by the number of failed attempts, the time required for plate fixation, the influence of surgical experience as well as the learning success for each individual coupling mechanism. Moreover, the feasibility of each mechanism was evaluated by a questionnaire.
    UNASSIGNED: The results demonstrate that plates employing grooved and pressure-sliding coupling mechanisms exhibit fewer failed attempts and reduce trial times, especially in contrast to sole sliding mechanisms. Furthermore, our study revealed that proficiency in endoscopic procedures significantly influenced the outcome. Notably, the subjective evaluation of the participants show that the pressure base and pressure-slide base plate designs are the most supportive and feasible designs.
    UNASSIGNED: In summary, the present study evaluates for the first-time different plate and coupling designs for minimal-invasive surgery, indicating a superior feasibility for plates with a grooved and pressure-sliding mechanism.
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  • 文章类型: Editorial
    大约45%的恶性骨肿瘤发生在16岁以下,未成熟骨骼患者的生长板牺牲的重要结果之一是肢体不平等。直到1990年代初,这些患者的治疗选择是旋转成形术或截肢.结合成像的多模态方法,化疗,和手术技术使肢体保留方法的发展取得了令人满意的效果。为了克服不平等问题,可扩张假体已在1980年代开发。多年来,可扩展的内置假体替代品已得到改进,现在已成为公认的安全替代品。与需要多次外科手术的微创可扩张假体相比,无创假体似乎是有利的。但并发症发生率仍然很高。因此,虽然可扩张假体并不是治疗骨骼未成熟儿童骨肉瘤的最终答案,在成年之前,他们仍然是一个合适的临时选择。由于报告的并发症发生率高,这些程序需要丰富的经验,建议仅在专门的癌症中心使用。
    Approximately 45 percent of malignant bone tumors are seen under the age of 16 and one of the important results of growth plate sacrification in patients with immature skeletons is limb inequality. Until the early 1990s, the treatment options for these patients were rotationplasty or amputation. Multimodal approaches that combine imaging, chemotherapy, and surgical techniques have enabled the development of limb-preserving methods with satisfactory results. In order to overcome inequality problems, expandable prostheses have been developed in the 1980s. Extendable endoprosthesis replacements have been improved over the years and are now an established and safe alternative. Noninvasive prostheses appear to be advantageous compared to minimally invasive expandable prostheses that require multiple surgical procedures, but the complication rate remains high. Therefore, although expandable prostheses are not the definitive answer to the treatment of bone sarcomas in skeletally immature children, they are still a suitable interim choice until full adulthood is achieved. Due to reported high complication rates, the procedures require significant experience and are recommended for use only in specialized cancer centers.
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  • 文章类型: Meta-Analysis
    目的:目前的证据尚不清楚射频消融(RFA)和微波消融(MWA)作为甲状腺良性结节的微创治疗的疗效和安全性。这项研究的主要目的是澄清这些问题。
    方法:使用Cochrane图书馆进行了全面搜索,Scopus,欧洲PMC,和Medline数据库直到10月10日,2023年,使用相关关键词的组合。这项研究纳入了比较RFA和MWA对良性甲状腺结节的文献。主要结果是从基线到随访的体积减少率(VRR)。次要结果是症状评分,化妆品评分,消融时间,主要并发症发生率,出血,声音嘶哑,皮肤烧伤,咳嗽,交感神经损伤.我们使用非随机干预研究中的偏倚风险(ROBINS-I)工具来评估纳入研究中的偏倚风险。我们采用随机效应模型来分析结果表示的标准化平均差(SMD)和比值比。
    结果:纳入了9项2707个结节的研究。我们的荟萃分析结果表明,在1个月(SMD0.06;95%置信区间[CI]:-0.13至0.26;P=0.52)和3个月(SMD0.11;95%CI:-0.03至0.25;P=0.12)随访期间,RFA和MWA在VRR方面的疗效相似。在随访6(SMD0.25;95%CI:0.06-0.43;P=0.008)和12个月(SMD0.38;95%CI:0.17至0.59;P<0.001)时,RFA的VRR明显高于MWA。RFA和MWA在症状评分上没有显著差异,美容成绩,或者并发症的发生率,包括出血,声音嘶哑,皮肤烧伤,咳嗽,交感神经损伤.
    结论:在6个月和12个月的随访中,RFA显示VRR高于MWA,具有可比的安全性。
    OBJECTIVE: The current body of evidence lacks clarity regarding the comparative efficacy and safety of radiofrequency ablation (RFA) and microwave ablation (MWA) as minimally invasive treatments for benign thyroid nodules. The primary objective of this study is to clarify these concerns.
    METHODS: A comprehensive search was conducted using the Cochrane Library, Scopus, Europe PMC, and Medline databases until October 10th, 2023, using a combination of relevant keywords. This study incorporated literature that compared RFA and MWA for benign thyroid nodules. The primary outcome was the volume reduction ratio (VRR) from baseline to follow-up. Secondary outcomes were symptom score, cosmetic score, ablation time, major complications rate, hemorrhage, hoarseness, skin burn, cough, and sympathetic nerve injury. We used Risk of Bias in Non-randomized Studies - of Interventions (ROBINS-I) tool to assess the risk of bias in the included studies. We employed random effects models to analyze the standardized mean difference (SMD) and odds ratio for the presentation of outcomes.
    RESULTS: Nine studies with 2707 nodules were included. The results of our meta-analysis indicated similar efficacy between RFA and MWA in terms of VRR during the 1 (SMD 0.06; 95% confidence interval [CI]: -0.13 to 0.26; P = 0.52) and 3 (SMD 0.11; 95% CI: -0.03 to 0.25; P = 0.12) months of follow-up. VRR was significantly higher in RFA than in MWA at the 6 (SMD 0.25; 95% CI: 0.06-0.43; P = 0.008) and 12 month of follow-up (SMD 0.38; 95% CI: 0.17 to 0.59; P < 0.001). There were no significant differences between RFA and MWA in symptom scores, cosmetic scores, or the incidence of complications, including hemorrhage, hoarseness, skin burn, cough, and sympathetic nerve injury.
    CONCLUSIONS: RFA showed a higher VRR than MWA at 6 and 12-month follow-ups, with a comparable safety profile.
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  • 文章类型: Journal Article
    背景:室管膜导管(CVC)已成为囊性颅咽管瘤和蛛网膜囊肿的有希望的治疗选择,但它们在治疗源自神经胶质瘤或脑转移(BM)的囊肿方面的有效性仍然有限.本研究旨在分析CVC在胶质瘤和BM患者中的疗效以及与手术相关的发病率。
    方法:这项单中心回顾性研究包括2010年1月至2021年1月12日之前治疗过的神经胶质瘤或BMs的获得性占位性囊肿的所有患者。
    结果:共确定57例患者,中位年龄为47岁(IQR38-63)。局灶性神经功能缺损是60%患者的主要症状(n=34),其次是14%的头痛(n=8),癫痫发作占21.1%(n=12)。在所有情况下,除一例由于位置不当而需要进行翻修手术外,均实现了准确的CVC放置。CVC植入后三个月,70%的患者症状改善。多因素logistic回归分析确定了在疾病过程中占位性囊肿的发展(OR1.014;p=0.04)和术后囊肿体积减少(OR1.055;p=0.05)是CVC放置后术后症状改善的重要预测因素。随访3例,平均5个月(3-9个月)后,在MRI中观察到局部囊肿复发。其他并发症包括3例继发性吸收不良性脑积水和1例脑膜瘤。
    结论:立体定向植入CVC是一种有效的治疗选择,适用于患有有症状的BMs或神经胶质瘤占位性囊肿的患者,独立于他们的CNSWHO等级。然而,警惕的方法对于潜在的并发症和治疗失败至关重要.
    BACKGROUND: Cysto-ventricular catheters (CVC) have emerged as promising treatment option for cystic craniopharyngioma and arachnoid cysts, but their effectiveness in treating cysts originating from glioma or brain metastasis (BM) remains limited. This study aimed to analyze the efficacy of CVC in patients with glioma and BM as well as procedure-associated morbidity.
    METHODS: This single-center retrospective study included all patients treated with CVC placement for acquired space-occupying cysts deriving from previously treated glioma or BMs between 1/2010 and 12/2021.
    RESULTS: A total of 57 patients with a median age of 47 years (IQR 38-63) were identified. Focal neurological deficits were the predominant symptoms in 60% of patients (n = 34), followed by cephalgia in 14% (n = 8), and epileptic seizures in 21.1% (n = 12). Accurate CVC placement was achieved in all but one case requiring revision surgery due to malposition. Three months after CVC implantation, 70% of patients showed symptomatic improvement. Multivariate logistic regression analysis identified the development of space-occupying cysts later in the course of the disease (OR 1.014; p = 0.04) and a higher reduction of cyst-volume postoperatively (OR 1.055; p = 0.05) were significant predictors of postoperative symptomatic improvement following CVC placement. Local cyst recurrence was observed in three cases during follow-up MRI after an average time of 5 months (range 3-9 months). Further complications included secondary malresorptive hydrocephalus in three cases and meningeosis neoplastica in one patient.
    CONCLUSIONS: Stereotactic implantation of CVC is an efficient treatment option for patients suffering from symptomatic space-occupying cysts from BMs or glioma, independently from their CNS WHO grade. However, a vigilant approach is crucial regarding potential complications and treatment failures.
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  • 文章类型: Meta-Analysis
    背景:内窥镜辅助保乳手术(E-BCS)是10年前开发的一种用于乳腺癌治疗的方法,其潜在优势是不太明显的瘢痕形成。然而,支持其优于常规保乳手术(C-BCS)的证据尚不清楚.
    目的:本研究旨在比较E-BCS和C-BCS治疗早期乳腺癌的疗效。
    方法:使用Medline中的特定关键字对相关文章进行了全面搜索,Scopus,ClinicalTrials.gov,和Cochrane图书馆PubMed直到10月17日,2022年。收集在早期乳腺癌患者中比较E-BCS和C-BCS的临床试验。
    结果:我们对9项研究的分析显示,E-BCS与较短的切口长度相关[平均差(MD)-6.50cm(95%CI-10.75,-2.26),p=0.003,I2=99%]和更高的化妆品评分[MD2.69(95%CI1.46,3.93),与C-BCS相比,p<0.0001,I2=93%]。然而,E-BCS的手术时间较长[MD35.95分钟(95%CI19.12,52.78),p<0.0001,I2=93%]和更大的排出量[MD62.91mL(95%CI2.55,123.27),p=0.04,I2=79%]。失血量无显著差异(p=0.06),排水持续时间(p=0.28),术后并发症(p=0.69),或局部复发(p=0.59)。
    结论:我们的研究表明,与C-BCS相比,E-BCS治疗早期乳腺癌的切口长度更短,美容效果更好。然而,E-BCS需要更长的操作时间并且具有更大的排水量。需要进一步的研究来证实这些发现。
    BACKGROUND: Endoscopy-assisted breast conserving surgery (E-BCS) was developed over 10 years ago as a method for breast cancer treatment with the potential advantage of less noticeable scarring. However, the evidence supporting its superiority over conventional breast conserving surgery (C-BCS) remains unclear.
    OBJECTIVE: This study aims to compare the outcomes of E-BCS and C-BCS for the treatment of early breast cancer.
    METHODS: A comprehensive search for relevant articles was performed using specific keywords in Medline, Scopus, ClinicalTrials.gov, and Cochrane Library PubMed up to October 17th, 2022. Clinical trials that compared E-BCS with C-BCS in early breast cancer patients were collected.
    RESULTS: Our analysis of nine studies revealed that E-BCS was associated with shorter incision length [Mean Difference (MD) -6.50 cm (95% CI -10.75, -2.26), p = 0.003, I2 = 99%] and higher cosmetic score [MD 2.69 (95% CI 1.46, 3.93), p < 0.0001, I2 = 93%] compared with C-BCS. However, E-BCS had a longer operation time [MD 35.95 min (95% CI 19.12, 52.78), p < 0.0001, I2 = 93%] and greater drainage volume [MD 62.91 mL (95% CI 2.55, 123.27), p = 0.04, I2 = 79%]. There was no significant difference in blood loss volume (p = 0.06), drainage duration (p = 0.28), postoperative complications (p = 0.69), or local recurrence (p = 0.59) between the two groups.
    CONCLUSIONS: Our study suggests that E-BCS offers a shorter incision length and better cosmetic outcome compared with C-BCS in the treatment of early breast cancer. However, E-BCS requires a longer operation time and has greater drainage volume. Further studies are needed to confirm these findings.
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  • 文章类型: Journal Article
    背景:经皮内固定治疗舟骨骨折需要准确的导针插入。计算机辅助导航和机器人手术的出现可能为该问题提供有希望的解决方案。方法:本研究介绍了具有计算机辅助导航系统的自动多自由度(DOF)手术机器人的开发,专注于经皮舟骨导向销插入。使用这个设备,还有一个3D透视装置,我们对10具尸体进行了经皮舟骨导向销插入的实验研究,以验证系统的可行性和可靠性。结果:平均手术时间为29.1(SD4.3)分钟。尸体需要不超过两次尝试来实现所需的金属丝放置,平均定位误差为2.0(SD0.3)mm,平均角度偏差为3.6(SD0.7)°。在整个研究过程中,在手术过程中,每个尸体平均需要进行2.2次全周期透视检查,术前不需要CT扫描。结论:结果表明,使用自动手术机器人进行经皮舟骨导向销插入是可行的,可以达到预期的效果。
    Background: Percutaneous fixation of scaphoid fractures need accurate guide pin insertion. The emergence of computer-assisted navigation and robotic surgery may provide a promising solution to this problem. Methods: This study presents the development of an automatic multi-degrees of freedom (DOF) surgical robot with computer-assisted navigation system, focusing on percutaneous scaphoid guide pin insertion. Using this device, along with a 3D fluoroscopy unit, we have conducted an experimental study on 10 cadavers for percutaneous scaphoid guide pin insertion to verify the feasibility and reliability of the system. Results: The mean operative duration was 29.1 (SD 4.3) minutes. The cadavers required no more than two attempts to achieve desired wire placement, with the mean positioning-error being 2.0 (SD 0.3) mm and the mean angle-deviation 3.6 (SD 0.7)°. Throughout the study, a mean of 2.2 full-cycle fluoroscopy attempts was required for each cadaver during surgery, and no preoperative CT scan was needed. Conclusions: The outcomes show that using the automatic surgical robot to perform the percutaneous scaphoid guide pin insertion is feasible and desired results can be achieved.
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  • 文章类型: Journal Article
    简介:胰十二指肠切除术,通常被称为Whipple程序,是一种复杂的外科技术,用于治疗各种胰腺和壶腹周围病变。微创PD的创建是为了增强传统的结果,开放技术。然而,重建阶段已被认为是广泛采用腹腔镜技术的实质性障碍。一些研究评估和案例研究建议在重建步骤中将机器人技术作为促进者。我们提出了一种混合方法,将腹腔镜的多功能性与达芬奇Xi的视觉和运动优势相结合,以最大程度地提高重建的精度。我们的建议是基于我们机构在标准化不同外科手术和方案方面的经验。方法本文重点介绍本机构机器人辅助PD的结果。11例患者在1月1日之间接受了机器人辅助腹腔镜PD,2020年3月7日,2023年(N=11)。涉及两种方法:混合PDA型(N=6)和混合PDB型(N=5)。结果在11例接受混合PD的患者中,其中大多数为男性(81.8%),平均年龄为61.9岁(45~75岁).平均手术时间为618分钟(范围为480至780分钟)。平均失血量为159mL(范围为50至350mL)。对恶性肿瘤进行了十次手术,对神经内分泌十二指肠肿瘤进行了一次手术;检索到的平均淋巴结数为16.2(范围为11至24个淋巴结),所有标本均通过病理学报告为R0。平均住院时间为18天(范围为8至40天)。5例患者需要再次手术(N=5),全部来自A型组,1例(N=1)患者死亡。在索引程序中没有转换为开放手术,也没有临床相关的术后胰瘘。30天死亡率为零,由于大面积肺栓塞,90天1例死亡。结论混合方法有利于腹腔镜和机器人方法的优点。虽然腹腔镜在操纵肠道时更安全,并允许RouxenY重建和胃胰腺吻合,机器人辅助使外科医生能够高精度地进行精细吻合。学习曲线最重要的因素是标准化和仔细的患者选择以及逐步的方法。
    Introduction: Pancreaticoduodenectomy, commonly known as the Whipple procedure, is a complex surgical technique employed for the treatment of various pancreatic and periampullary pathologies. Minimally invasive PD was created in an attempt to enhance the outcomes of the traditional, open technique. However, the reconstruction phase has been recognized as a substantial barrier to widespread adoption of the laparoscopic technique. Several research appraisals and case studies recommend the robotic technique as a facilitator during the reconstruction steps. We propose a hybrid approach to combine the versatility of laparoscopy and the visual and motor advantages of the DaVinci Xi in order to maximize the precision of the reconstruction. Our suggestion is based on the experience that our institution has had with the standardization of different surgical procedures and protocols. Methods This article is focused on the outcomes of robotic assisted PD in our institution. Eleven patients underwent robotic assisted laparoscopic PD between 1st January, 2020 and 7th March, 2023 (N=11). There were two approaches involved: hybrid PD type A (N=6) and hybrid PD type B (N=5). Results Of the eleven patients who underwent hybrid PD, most of them were men (81.8%) and mean age was 61.9 years-old (range 45 to 75 years). The mean operative duration was 618 minutes (range 480 to 780 minutes). Mean blood loss was 159 mL (range 50 to 350 mL). Ten operations were performed for malignancy and one for neuroendocrine duodenal tumour; the mean number of lymph nodes retrieved was 16.2 (range 11 to 24 nodes) and all the specimens were reported by pathology as R0. Mean hospital stay was 18 days (range 8 to 40 days). Reoperations were necessary in five patients (N=5), all from the type A group, and mortality occurred in one (N=1) patient. There were no conversions to open surgery during the index procedures as well as no clinically relevant postoperative pancreatic fistulae. Thirty-day mortality was nil, with 1 mortality at 90-days due to massive pulmonary embolism. Conclusions The hybrid approach facilitates the advantages of both laparoscopic and robotic approaches. While laparoscopy is safer in manipulating the bowel and allows the Roux en Y reconstruction and gastro-pancreatic anastomosis, the robotic assistance enables the surgeon to perform delicate anastomosis with a high accuracy. The learning curve\'s most important element is standardization and careful patient selection along with a stepwise approach.
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  • 文章类型: Journal Article
    背景:多项研究表明,糖尿病患者开放性踝关节或TTC关节固定术的并发症发生率相当高,翻修手术和溃疡。已提出与多氟碳化物患者结合使用的广泛方法是并发症发生率增加的原因。
    方法:单中心,前瞻性病例对照研究比较关节镜与足Charcot神经关节病患者的开放性踝关节固定术。18例脓毒症Charcot神经关节病SandersIII-IV患者接受了关节镜下踝关节固定术和TSF(TaylorSpatialFrame®)固定,并结合了感染治疗和后足重新对准所需的不同附加程序。SandersIV患者的后足重新对准需要踝关节固定术,关节炎或在感染的情况下。12例患者接受了开放式踝关节固定术和TSF固定术以及各种其他手术的治疗。
    结果:两组的放射学数据均显示出显着改善。关节镜组的并发症发生率明显较低。主要并发症与治疗性抗凝和吸烟之间存在显着相关性。
    结论:在糖尿病和足底溃疡的高危患者中,可以证明在关节镜下进行踝关节固定术并使用TSF作为固定手段进行足中部截骨术的良好结果。
    BACKGROUND: Several studies demonstrated a considerable complication rate for open ankle or TTC arthrodesis in patients with diabetes, revision surgery and ulceration. Extensive approaches in combination with multimorbide patients have been suggested as the rationale behind the increased complication rate.
    METHODS: Single-centre, prospective case-control study compared arthroscopic vs. open ankle arthrodesis in patients with Charcot Neuro-Arthropathy of the foot. 18 patients with septic Charcot Neuro-Arthropathy Sanders III-IV received an arthroscopic ankle arthrodesis with TSF (Taylor Spatial Frame®) fixation combined with different additional procedures required for infect treatment and hindfoot realignment. The ankle arthrodesis was required for the realignment of the hindfoot in Sanders IV patients, arthritis or in case of infection. 12 patients were treated with open ankle arthrodesis and TSF fixation combined with various additional procedures.
    RESULTS: A significant improvement has been shown in radiological data in both groups. A significant lower complication rate has been registered in arthroscopic group. A significant correlation was seen between major complications and therapeutic anticoagulation as well as smoking.
    CONCLUSIONS: In high-risk patients with diabetes and plantar ulceration excellent results could be demonstrated in arthroscopically performed ankle arthrodesis with midfoot osteotomy using TSF as fixation devise.
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  • 文章类型: Multicenter Study
    背景:腹腔镜辅助(LALR)和手辅助(HALR)肝切除术在从开放手术过渡到纯LLR的早期采用阶段已被外科医生使用。迄今为止,与LLR相比,关于LALR或HALR结局的数据报告有限.目的是比较LALR和HALR与纯LLR术后的围手术期结局。
    方法:这是一项国际多中心分析,分析了2004年至2019年间在21个中心接受微创肝切除术的6609例患者。在LALR和HALR与LLR之间的倾向评分匹配(PSM)比较后分析围手术期结果。
    结果:5279例符合研究标准,其中5033例接受LLR(95.3%),146例接受LALR(2.8%),100例接受HALR(1.9%)。在1:4PSM之后,LALR与较差的结果相关,如术后停留时间较长所证明,更高的再入院率,较高的主要发病率和较高的住院死亡率。同样,HALR和LLR之间的1:6PSM比较也显示了与HALR相关的较差结果,如通过较高的开放转化率和较高的输血率所显示的。所有3种方法的技术变体都表现出相同的肿瘤根性(R1率)。
    结论:与单纯LLR相比,在学习曲线期间进行的LALR和HALR与较差的围手术期结局相关。
    Laparoscopic-assisted (LALR) and hand-assisted (HALR) liver resections have been utilized during the early adoption phase by surgeons when transitioning from open surgery to pure LLR. To date, there are limited data reporting on the outcomes of LALR or HALR compared to LLR. The objective was to compare the perioperative outcomes after LALR and HALR versus pure LLR.
    This is an international multicentric analysis of 6609 patients undergoing minimal-invasive liver resection at 21 centers between 2004 and 2019. Perioperative outcomes were analyzed after propensity score matching (PSM) comparison between LALR and HALR versus LLR.
    5279 cases met study criteria of whom 5033 underwent LLR (95.3%), 146 underwent LALR (2.8%) and 100 underwent HALR (1.9%). After 1:4 PSM, LALR was associated with inferior outcomes as evidenced by the longer postoperative stay, higher readmission rate, higher major morbidity rate and higher in-hospital mortality rate. Similarly, 1:6 PSM comparison between HALR and LLR also demonstrated poorer outcomes associated with HALR as demonstrated by the higher open conversion rate and higher blood transfusion rate. All 3 approaches technical variants demonstrated the same oncological radicality (R1 rate).
    LALR and HALR performed during the learning curve was associated with inferior perioperative outcomes compared to pure LLR.
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  • 文章类型: Journal Article
    目的:内窥镜脊柱手术是一种在全球范围内扩展的技术,与显微外科手术方法相比,其对于椎管狭窄的治疗具有较小的侵入性。然而,层间全内镜减压术(FED)疗效与传统的显微手术减压术(MSD)在腰椎管狭窄症患者中仍然很少。我们进行了一个病例匹配的比较治疗的成功与临床考虑,实验室,和放射学预测因子。
    方法:我们纳入了88例表现为腰椎中央椎管狭窄的连续患者(FED:36/88,40.9%;MSD:52/88,59.1%)。手术相关(手术时间,并发症,停留时间(LOS)美国麻醉医师协会身体状况(ASA)评分,C反应蛋白(CRP),白细胞计数,方法方面(单边/双边),患者相关结局指标(PROM)(Oswestry残疾指数(ODI),疼痛数字评定量表(NRS;腿部-,背部疼痛),EuroQol问卷(eQ-5D),核心成果计量指数(COMI)),和放射学(硬脑膜袋横截面积,Schizas得分(SC),左右横向凹陷高度,和刻面角度,分别)在不同时间点提取参数,直至1年随访。使用Spearman秩相关分析了PROM之间的关系。手术相关的结果参数与以患者为中心和放射学结果相关,利用回归模型确定倾向评分匹配的预测因子。
    结果:并发症(最常见的是血肿引起的残余感觉运动功能障碍和再狭窄)发生率在FED组(33.3%)高于MSD组(13.5%)(p<0.05),而FED组的所有并发症均在前20例FED患者中观察到。FED的手术时间较高,而MSD组的LOS较高。年龄,SC,CRP显示与PROMs有显著关联。我们没有观察到内镜与显微外科手术组的ODI和COMI之间的相关性显著高,两者都与eQ-5D呈负相关,而这些PROM与NRS结果的相关性不太明显。
    结论:内窥镜治疗腰椎管狭窄症与传统的显微外科手术方法相似。尽管在我们的单中心研究经验中,FED与较高的并发症发生率相关,并发症的分布表明手术学习曲线是这些发现的主要因素.考虑手术学习曲线的未来长期前瞻性研究对于这些技术的可靠比较是必要的。
    Endoscopic spine surgery is a globally expanding technique advocated as less invasive for spinal stenosis treatment compared to the microsurgical approach. However, evidence on the efficiency of interlaminar full-endoscopic decompression (FED) vs. conventional microsurgical decompression (MSD) in patients with lumbar spinal stenosis is still scarce. We conducted a case-matched comparison for treatment success with consideration of clinical, laboratory, and radiologic predictors.
    We included 88 consecutive patients (FED: 36/88, 40.9%; MSD: 52/88, 59.1%) presenting with lumbar central spinal stenosis. Surgery-related (operation time, complications, length of stay (LOS), American Society of Anesthesiologists physical status (ASA) score, C-reactive protein (CRP), white blood cell count, side of approach (unilateral/bilateral), patient-related outcome measures (PROMs) (Oswestry disability index (ODI), numeric rating scale of pain (NRS; leg-, back pain), EuroQol questionnaire (eQ-5D), core outcome measures index (COMI)), and radiological (dural sack cross-sectional area, Schizas score (SC), left and right lateral recess heights, and facet angles, respectively) parameters were extracted at different time points up to 1-year follow-up. The relationship of PROMs was analyzed using Spearman\'s rank correlation. Surgery-related outcome parameters were correlated with patient-centered and radiological outcomes utilizing a regression model to determine predictors for propensity score matching.
    Complication (most often residual sensorimotor deficits and restenosis due to hematoma) rates were higher in the FED (33.3%) than MSD (13.5%) group (p < 0.05), while all complications in the FED group were observed within the first 20 FED patients. Operation time was higher in the FED, whereas LOS was higher in the MSD group. Age, SC, CRP revealed significant associations with PROMs. We did not observe significant differences in the endoscopic vs. microsurgical group in PROMs. The correlation between ODI and COMI was significantly high, and both were inversely correlated with eQ-5D, whereas the correlations of these PROMs with NRS findings were less pronounced.
    Endoscopic treatment of lumbar spinal stenosis was similarly successful as the conventional microsurgical approach. Although FED was associated with higher complication rates in our single-center study experience, the distribution of complications indicated surgical learning curves to be the main factor of these findings. Future long-term prospective studies considering the surgical learning curve are warranted for reliable comparisons of these techniques.
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