Magnetic resonance

磁共振
  • 文章类型: Journal Article
    先前对运动人群的研究表明,没有症状或已知病理的个体可能存在异常磁共振成像(MRI)发现。将这种理解扩展到芭蕾舞,特别是关于脚和脚踝,指导给舞者的医疗建议很重要。
    评估无症状芭蕾舞演员的足踝MRI扫描,重点是骨髓水肿和后踝关节,并调查这些MRI结果是否会在1年内出现症状。
    案例系列;证据级别,4.
    总共,31名健康舞者(62英尺/脚踝;15名男性和16名女性;年龄,26.5±4.3年),从一家精英专业芭蕾舞团招募了全部能力跳舞的人。使用3TMRI获得了脚和脚踝的正交3平面短tau反转恢复成像,并由2名肌肉骨骼放射科医生使用标准化评估表审查了图像。记录了公司的伤害,并评估了MRI阳性结果与随后12个月内需要医疗护理的任何伤害的相关性。
    在62英尺和脚踝中,共有51(82%)的骨髓水肿面积≥1。骨髓水肿最常见的位置是距骨(n=41;66%),其次是第一meta骨(n=14;23%)。在5(8%)和8(13%)脚踝中观察到三角和Stieda过程,分别。其中,2μs三角菌显示骨髓水肿。在前、后足骨膜关节和距下关节中观察到48%的液体,63%,63%的关节,分别。观察到足部和踝关节肌腱周围有液体,最普遍的是长屈屈肌腱(n=13;21%)。两名在MRI上有阳性发现的舞者随后在接下来的12个月中出现了症状。
    在无症状的专业芭蕾舞演员的脚和踝关节中,MRI阳性结果很常见。大多数在12个月内不会导致需要医疗护理的症状发展。在建议修改活动或进一步干预之前,需要根据舞者的临床表现仔细解释MRI结果。
    UNASSIGNED: Previous research in sport populations has demonstrated that abnormal magnetic resonance imaging (MRI) findings may be present in individuals without symptoms or known pathology. Extending this understanding to ballet, particularly in relation to the foot and ankle, is important to guide medical advice given to dancers.
    UNASSIGNED: To assess foot and ankle MRI scans in asymptomatic ballet dancers focusing on bone marrow edema and the posterior ankle and to investigate whether these MRI findings would become symptomatic within 1 year.
    UNASSIGNED: Case series; Level of evidence, 4.
    UNASSIGNED: In total, 31 healthy dancers (62 feet/ankles; 15 male and 16 female; age, 26.5 ± 4.3 years) who were dancing in full capacity were recruited from an elite professional ballet company. Orthogonal 3-plane short tau inversion recovery imaging of both feet and ankles was obtained using 3T MRI and the images were reviewed using a standardized evaluation form by 2 musculoskeletal radiologists. Injuries in the company were recorded and positive MRI findings were assessed for correlation with any injuries requiring medical attention during the subsequent 12 months.
    UNASSIGNED: A total of 51 (82%) of the 62 feet and ankles had ≥1 area of bone marrow edema. The most common locations of bone marrow edema were the talus (n = 41; 66%), followed by first metatarsal (n = 14; 23%). Os trigonum and Stieda process were seen in 5 (8%) and 8 (13%) ankles, respectively. Among them, 2 os trigona showed bone marrow edema. Fluid in the anterior and posterior talocrural joints and the subtalar joint was observed in 48%, 63%, and 63% of these joints, respectively. Fluid around foot and ankle tendons was observed, with the most prevalent being the flexor hallucis longus tendon (n = 13; 21%). Two dancers who had positive findings on their MRI subsequently developed symptoms during the next 12 months.
    UNASSIGNED: Positive MRI findings are commonplace in the foot and ankle of asymptomatic professional ballet dancers. The majority do not result in the development of symptoms requiring medical attention within 12 months. Careful interpretation of MRI findings with the dancer\'s clinical picture is required before recommending activity modification or further intervention.
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  • 文章类型: Editorial
    暂无摘要。
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  • 文章类型: Journal Article
    磁共振成像(MRI)用于确定极鳕鱼的性别(BoreogadussaidaLepechin,1774)(Actinopterygii:Gadidae),并跟踪个体动物的性腺发育。将单个未麻醉的鱼转移到临床前9.4TMRI扫描仪内的测量室中,并连续灌注充气海水。平均3.5小时的筛查程序,由一组不同方向的MRI扫描组成,每4周在相同的一组繁殖B.saida(n=10)上重复一次,体长约20厘米。适应的多层流补偿快速低角度射击(FcFLASH)和具有松弛增强(RARE)协议的快速采集,面内分辨率为313μm,采集时间为2.5min,用于可视化各种器官的形态,包括视野(FOV)内的性腺。MR图像提供了高分辨率,能够确定特定的性别,性腺体积的计算,和卵母细胞大小的测定。从2021年11月到2022年2月产卵前不久,性腺成熟持续了4个月。在观察期间,男性的性腺体积增加了2.3-25.5%,女性的性腺体积增加了11.5-760.7%。从10月到2月,卵母细胞直径从427μm(n=1)增加到1346±27μm(n=4)。有趣的是,单个卵母细胞显示MR对比度随时间的变化,这可归因于卵母细胞的形态发育。结果与经典侵入性研究的先前文献数据非常吻合。所提出的方法在各种生态生理应用中具有巨大的潜力,例如在不同环境条件下监测内部器官的自然或延迟发育或性别确定。
    Magnetic resonance imaging (MRI) was applied to determine the sex of polar cod (Boreogadus saida Lepechin, 1774) (Actinopterygii: Gadidae) and to follow the gonadal development in individual animals over time. Individual unanaesthetised fish were transferred to a measurement chamber inside a preclinical 9.4 T MRI scanner and continuously perfused with aerated seawater. A screening procedure at an average of 3.5 h, consisting of a set of MRI scans of different orientations, was repeated every 4 weeks on the same set of reproducing B. saida (n = 10) with a body length of about 20 cm. Adapted multi-slice flow-compensated fast low-angle shot (FcFLASH) and rapid acquisition with relaxation enhancement (RARE) protocols with an in-plane resolution of 313 μm and an acquisition time of 2.5 min were used to visualise the morphology of various organs, including the gonads within the field of view (FOV). The MR images provided high resolution, enabling specific sex determination, calculation of gonad volumes, and determination of oocyte sizes. Gonad maturation was followed over 4 months from November 2021 until shortly before spawning in February 2022. The gonad volume increased by 2.3-25.5% for males and by 11.5-760.7% for females during the observation period. From October to February, the oocyte diameter increased from 427 μm (n = 1) to 1346 ± 27 μm (n = 4). Interestingly, individual oocytes showed changes in MR contrast over time that can be attributed to the morphological development of the oocytes. The results fit well with previous literature data from classical invasive studies. The presented approach has great potential for various ecophysiological applications such as monitoring natural or delayed development of internal organs or sex determination under different environmental conditions.
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  • 文章类型: Journal Article
    目的:评估使用1.5T磁共振(MR)-直线加速器MR-直线加速器在妇科高剂量率(HDR)近距离放射治疗中成像的可行性。##xD;方法:用于MR图像质量控制的调试测量,几何失真,停留位置精度,根据美国近距离放射治疗协会的建议,对串联和环形涂药器进行了涂药器重建和端到端测试,国际辐射单位和测量委员会以及西班牙医学物理学会近距离放射治疗工作组的报告。将基于MR的IGABT的值与计算机断层扫描(CT)的相应值进行比较。 结果:与CT图像相比,MR图像的测量失真小于0.50mm。所有停留位置的3D位移之间的差异为0.66mm和0.62mm的串联和环,分别。对于使用膜获得的距涂药器尖端的距离,最大差为0.64mm。右侧和左侧A点的CT和MR剂量差异分别为0.9%和-0.7%,分别。在CT和MR的剂量分布方面观察到类似的结果。伽马合格率分别为99.3%和99.5%,分别。
结论:在妇科近距离放射治疗的放射治疗服务中使用MR直线加速器的MR图像被证明是可行的,安全和精确,因为几何差异小于1毫米,与用于相同目的的CT图像相比,剂量学差异小于1%。
    OBJECTIVE: To evaluate the feasibility of use of an 1.5 T magnetic resonance (MR)-linear accelerator MR-linac for imaging in gynaecologic high-dose-rate (HDR) brachytherapy. Method: Commissioning measurements for MR images quality control, geometric distortion, dwell position accuracy, applicator reconstruction and end-to-end test for a tandem-and-ring applicator were performed following the recommendations of American Brachytherapy Society, International Commission on Radiation Units and Measurements and Report of the Brachytherapy Working Group of the Spanish Society of Medical Physics. The values for MR-based IGABT were compared to the corresponding values with computed tomography (CT). Results: Measured distorsions for the MR images were less than 0.50 mm compared to the CT images. The differences between 3D displacements for all dwell positions were 0.66 mm and 0.62 mm for the tandem and ring, respectively. The maximum difference is 0.64 mm for the distances from the applicator tip obtained using the films. The CT and MR dose differences for the right and left \'A\' points were 0.9% and -0.7%, respectively. Similar results were observed in terms of dose distribution for CT and MR. The gamma passing rate was 99.3% and 99.5%, respectively. Conclusion: The use of MR images from an MR-linac used in a radiotherapy service for gynaecological brachytherapy was proved to be feasible, safe and precise as the geometrical differences were less than 1 mm, and the dosimetric differences were less than 1% when comparing to the use of CT images for the same purpose.
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  • 文章类型: Case Reports
    脑室内神经细胞瘤是一种发病率较低的中枢神经系统肿瘤。它主要影响年轻人,没有明显的性别偏好。主要症状包括头痛,恶心和呕吐。这些是由于脑脊液流阻塞引起的脑积水。关于诊断成像,可以通过一些特征怀疑神经细胞瘤,如周围囊肿,分叶状轮廓和桥接心室壁的隔片,给出一个“扇形”的外观。还有其他特征,但它们对诊断的特异性较低。神经细胞瘤的非典型变体甚至更罕见,并导致最坏的预后。非典型神经细胞瘤发展由Ki-67生物标志物鉴定的更高的增殖潜力和更高的复发率。关于非典型神经细胞瘤的影像学特征的研究较少。在这一点上,没有可靠的区别特征来区分非典型神经细胞瘤,尤其是由于其发病率低。我们介绍了一名20岁的女性患者,其症状为脑内高血压。大脑的CT和MRI显示一个肿块占据了左心室的身体,靠近Monro的孔.肿块主要为实性,周围有离散的囊肿和一些扇形区域。它还显示了幕上梗阻性脑积水的迹象。由于出血和血管结构受损,部分切除了肿瘤。免疫组织化学显示突触素阳性,Ki-67升高(7%),血管数量增加和中度核异型。手术后,病人持续有颅内高压的迹象,没有改善临床管理和需要积极的外科手术。虽然罕见,非典型神经细胞瘤需要更好的表征,尤其是通过成像,优化即时管理并探索新的治疗方案。
    Intraventricular neurocytoma is a low incidence central nervous system tumor. It predominantly affects young adults with no apparent gender predilection. The main symptoms include headache, nausea and vomiting. These result from hydrocephalus due to the obstruction of cerebrospinal fluid flow. On diagnostic imaging, neurocytoma can be suspected by some features, such as peripheral cysts, lobulated contours and septa that bridge the ventricular wall, giving a \"scalloped\" appearance. There are other characteristics, but they are less specific for the diagnosis. The atypical variant of neurocytoma is even rarer and leads to a worst prognosis. Atypical neurocytomas develop higher proliferative potential identified by the Ki-67 biomarker and higher recurrence rate. There are few studies about the imaging characteristics of atypical neurocytomas. At this point, there are no reliable distinctive features to differentiate atypical neurocytomas, especially due to their low incidence. We present the case of a 20-year-old female patient with symptoms of intracraneal hypertension. CT and MRI of the brain revealed a mass occupying the body of the left lateral ventricle, adjacent to the foramen of Monro. The mass was primarily solid with discrete peripheral cyst and a few scalloped areas. It also showed signs of supratentorial obstructive hydrocephalus. The tumor was partially removed because of bleeding and compromise of vascular structures. Immunohistochemistry revealed positive synaptophysin, elevated Ki-67 (7%), increased number of blood vessels and moderate nuclear atypia. After surgery, the patient persisted with signs of intracranial hypertension, not improving with clinical management and requiring aggressive surgical procedures. While rare, atypical neurocytoma requires a better characterization, especially through imaging, to optimize immediate management and explore new therapeutic options.
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  • 文章类型: Journal Article
    目的:本研究旨在评估常规二维(2D)盆腔超声与三维(3D)超声结合在评估梗阻性穆勒异常中的实际应用。
    方法:三级转诊医院的相关研究方法:使用计算机存储的数据收集2022年12月至2023年10月之间手术证实的梗阻性穆勒异常病例,并评估术前影像。需要急性出现腹痛和临床怀疑梗阻性苗勒管异常。所有研究参与者在确定性手术前都接受了盆腔超声检查,如果在入院前进行了MRI,则有或没有重复MRI。排除MRI和超声均未进行的情况,比如阴道横隔,无孔处女膜,仅有医源性宫颈损伤或穆勒畸形,没有阻塞性流出异常,如didelphys,bicornuate,或纵隔子宫。
    方法:29例女性中有27例(93.1%)经手术证实的诊断与盆腔超声检查结果一致。相比之下,在这项研究中,29例中只有24例通过MRI正确诊断(82.8%)。这项试点研究对两种技术进行了比较,特别关注阻塞性穆勒异常。盆腔超声的使用不仅有助于我们的外科手术实践,而且还显着改善了患者-医生咨询。
    结论:在处理梗阻性穆勒异常时,发现3D增强的常规盆腔超声可有效诊断,并且与MRI相当。
    OBJECTIVE: This study aimed to assess the practical application of conventional two-dimensional (2D) pelvic ultrasound in conjunction with three-dimensional (3D) ultrasound for evaluating obstructive Müllerian abnormalities.
    METHODS: Respective study in tertiary referral hospital METHOD: Computerized stored data was used to collect surgical confirmed obstructive Müllerian anomalies cases between December 2022 and October 2023 with presurgical imagings being evaluated. Acute presentation with abdominal pain and clinical suspicion of obstructive Müllerian abnormality were required for inclusion. All study participants underwent pelvic ultrasound prior to the definitive surgery, with or without a repeat MRI if one was performed previous to admission. Those situations where both MRI and ultrasound were not conducted were excluded, such as the transverse vaginal septum, imperforate hymen, iatrogenic cervical injury or Müllerian malformation alone without obstructive outflow anomalies like didelphys, bicornuate, or septate uterus.
    METHODS: The concordance between the surgically confirmed diagnosis and the pelvic ultrasound was reported in 27 of 29 women (93.1%). In contrast, only 24 of 29 cases were correctly diagnosed with MRI in this study (82.8%). This pilot study presents a comparison of two techniques, with a specific focus on obstructive Müllerian anomalies. The use of pelvic ultrasound not only assisted in our surgical practice but also significantly improved patient-doctor counseling.
    CONCLUSIONS: In managing obstructive Müllerian abnormalities, 3D-enhanced conventional pelvic ultrasound was found effective in diagnosis and was comparable to MRI.
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  • 文章类型: Journal Article
    我们提出了在8.6T和240GHz下的场域快速扫描(RS)电子顺磁共振(EPR)。要启用此技术,我们升级了家用EPR光谱仪与FPGA启用的数字化仪和实时处理软件。该软件利用希尔伯特变换来恢复同相(I)和正交(Q)通道,因此原始的吸收和分散信号,χ\'和χ\'\',从它们的组合大小(I2+Q2)。平均幅度比实时相干平均更简单,并且具有允许长时间尺度信号平均(高达至少2.5X106扫描)的附加益处,因为其消除了源-接收器相位漂移的影响。在相同的实验条件下,我们的快速扫描(RS)EPR提供的信噪比约为连续波(CW)EPR的两倍。按采集时间的平方根缩放后。我们应用RSEPR作为最近报道的时间分辨Gd-GdEPR(TiGGER)的扩展[Maity等人。,2023],它能够通过Gd-Gd偶极偶联的变化来监测光响应蛋白光循环过程中残基间距离的变化。RS,反对CW,以10ms的时间分辨率返回场扫描光谱作为时间的函数,因此,为TiGGER记录的静态场瞬态添加了第二个维度。我们能够使用RSTiGGER跟踪AsLOV2的时间依赖性和温度依赖性动力学,AsLOV2是燕麦中发现的光活化的光促激素域。此处呈现的结果将RSEPR的益处与Gd螯合物在高磁场下的改进的光谱分辨率和灵敏度相结合。在未来,磁场域RSEPR在高磁场可以使其他实时动力学过程的研究与时间分辨率,否则很难在溶液状态访问。
    We present field-domain rapid-scan (RS) electron paramagnetic resonance (EPR) at 8.6T and 240GHz. To enable this technique, we upgraded a home-built EPR spectrometer with an FPGA-enabled digitizer and real-time processing software. The software leverages the Hilbert transform to recover the in-phase (I) and quadrature (Q) channels, and therefore the raw absorptive and dispersive signals, χ\' and χ\'\', from their combined magnitude (I2+Q2). Averaging a magnitude is simpler than real-time coherent averaging and has the added benefit of permitting long-timescale signal averaging (up to at least 2.5×106 scans) because it eliminates the effects of source-receiver phase drift. Our rapid-scan (RS) EPR provides a signal-to-noise ratio that is approximately twice that of continuous wave (CW) EPR under the same experimental conditions, after scaling by the square root of acquisition time. We apply our RS EPR as an extension of the recently reported time-resolved Gd-Gd EPR (TiGGER) [Maity et al., 2023], which is able to monitor inter-residue distance changes during the photocycle of a photoresponsive protein through changes in the Gd-Gd dipolar couplings. RS, opposed to CW, returns field-swept spectra as a function of time with 10ms time resolution, and thus, adds a second dimension to the static field transients recorded by TiGGER. We were able to use RS TiGGER to track time-dependent and temperature-dependent kinetics of AsLOV2, a light-activated phototropin domain found in oats. The results presented here combine the benefits of RS EPR with the improved spectral resolution and sensitivity of Gd chelates at high magnetic fields. In the future, field-domain RS EPR at high magnetic fields may enable studies of other real-time kinetic processes with time resolutions that are otherwise difficult to access in the solution state.
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  • 文章类型: Journal Article
    背景:近年来,有越来越多的努力来利用低磁感应器件的潜在使用小于1T,称为低场MRI(LFMRI)。使用LFMRI系统,特别是在磁共振技术的早期。随着时间的推移,1.5和3T的磁感应值已成为临床设备的标准,主要是因为LFMRI系统的图像质量明显较低,例如,信噪比。近年来,由于人工智能图像处理的进步,有越来越多的努力,以利用低频MRI的潜在用途,诱导小于1T。这篇综述文章侧重于分析有关现代LFMRI系统的诊断功效的证据,以及LFMRI与1.5T系统在神经系统成像中的临床比较。肌肉骨骼系统,和胸部的器官,腹部,还有骨盆.
    方法:MEDLINE的系统文献综述,PubMed,Scopus,WebofScience,和CENTRAL2018-2023年的数据库按照推荐的PRISMA方案进行.对数据进行了分析,以确定比较准确性的研究,与可用的1.5TMRI相比,LFMRI技术的可靠性和诊断性能。
    结果:从选定的数据库中检索到总共1275篇出版物。仅选择符合所有预定义纳入标准的两篇文章进行详细评估。
    结论:与1.5TMRI相比,关于LFMRI的准确性和诊断性能的研究数量有限。目前的证据不足以得出任何明确的见解。需要更多的科学研究才能得出有关LFMRI技术有效性的结论。
    BACKGROUND: In recent years, there has been an increasing effort to take advantage of the potential use of low magnetic induction devices with less than 1 T, referred to as Low-Field MRI (LF MRI). LF MRI systems were used, especially in the early days of magnetic resonance technology. Over time, magnetic induction values of 1.5 and 3 T have become the standard for clinical devices, mainly because LF MRI systems were suffering from significantly lower quality of the images, e.g., signal-noise ratio. In recent years, due to advances in image processing with artificial intelligence, there has been an increasing effort to take advantage of the potential use of LF MRI with induction of less than 1 T. This overview article focuses on the analysis of the evidence concerning the diagnostic efficacy of modern LF MRI systems and the clinical comparison of LF MRI with 1.5 T systems in imaging the nervous system, musculoskeletal system, and organs of the chest, abdomen, and pelvis.
    METHODS: A systematic literature review of MEDLINE, PubMed, Scopus, Web of Science, and CENTRAL databases for the period 2018-2023 was performed according to the recommended PRISMA protocol. Data were analysed to identify studies comparing the accuracy, reliability and diagnostic performance of LF MRI technology compared to available 1.5 T MRI.
    RESULTS: A total of 1275 publications were retrieved from the selected databases. Only two articles meeting all predefined inclusion criteria were selected for detailed assessment.
    CONCLUSIONS: A limited number of robust studies on the accuracy and diagnostic performance of LF MRI compared with 1.5 T MRI was available. The current evidence is not sufficient to draw any definitive insights. More scientific research is needed to make informed conclusions regarding the effectiveness of LF MRI technology.
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  • 文章类型: Journal Article
    诊断成像在风湿性疾病的诊断过程中至关重要。鉴于这组疾病的异质性和新型治疗选择的巨大影响,有关最佳选择最合适技术的指南和建议会不断修订,放射科医师应始终保持最新状态。最后,由于不断的技术创新,我们将协助风湿病学先进技术和工具的逐步应用。
    Diagnostic imaging is essential in the diagnostic process of rheumatic diseases. Given the heterogeneity of this group of diseases and the tremendous impact of novel therapeutic options, guidelines and recommendations regarding the optimal choice of the most appropriate technique/s are continuously revised and radiologists should always be up-to-date. Last, because of the continuous technological innovations, we will assist to the progressive application of advanced techniques and tools in rheumatology.
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  • 文章类型: Journal Article
    我们旨在整合MR放射组学和动态血液学因素,以建立模型来预测食管鳞状细胞癌(ESCC)对新辅助放化疗(NCRT)的病理完全缓解(pCR)。
    回顾性纳入2014年9月至2022年9月接受NCRT和食管切除术的ESCC患者。所有患者均接受治疗前T2加权成像以及治疗前和治疗后的血液检查。以7:3的比例将患者随机分为训练集和测试集。基于MR影像组学和血液学因素构建机器学习模型来预测pCR,分别。开发了一个列线图模型来整合MR放射组学和血液学因素。通过曲线下面积(AUC)评估模型性能,灵敏度,特异性,阳性预测值和阴性预测值。
    共纳入82名患者,其中39人(47.6%)达到pCR。用四个血液学因子构建的血液学模型在测试集中具有0.628(95CI0.391-0.852)的AUC。选择1106个提取特征中的两个来构建AUC为0.821(95CI0.641-0.981)的影像组学模型。整合血液学因素和MR影像组学的列线图模型具有最好的预测性能。测试集中的AUC为0.904(95CI0.770-1.000)。
    构建了使用动态血液学因素和MR影像组学的集成模型,以准确预测ESCC中对NCRT的pCR,这可能有助于食道的个体化保留治疗。
    UNASSIGNED: We aimed to integrate MR radiomics and dynamic hematological factors to build a model to predict pathological complete response (pCR) to neoadjuvant chemoradiotherapy (NCRT) in esophageal squamous cell carcinoma (ESCC).
    UNASSIGNED: Patients with ESCC receiving NCRT and esophagectomy between September 2014 and September 2022 were retrospectively included. All patients underwent pre-treatment T2-weighted imaging as well as pre-treatment and post-treatment blood tests. Patients were randomly divided to training set and testing set at a ratio of 7:3. Machine learning models were constructed based on MR radiomics and hematological factors to predict pCR, respectively. A nomogram model was developed to integrate MR radiomics and hematological factors. Model performances were evaluated by areas under curves (AUCs), sensitivity, specificity, positive predictive value and negative.
    UNASSIGNED: A total of 82 patients were included, of whom 39 (47.6 %) achieved pCR. The hematological model built with four hematological factors had an AUC of 0.628 (95%CI 0.391-0.852) in the testing set. Two out of 1106 extracted features were selected to build the radiomics model with an AUC of 0.821 (95%CI 0.641-0.981). The nomogram model integrating hematological factors and MR radiomics had best predictive performance, with an AUC of 0.904 (95%CI 0.770-1.000) in the testing set.
    UNASSIGNED: An integrated model using dynamic hematological factors and MR radiomics is constructed to accurately predicted pCR to NCRT in ESCC, which may be potentially useful to assist individualized preservation treatment of the esophagus.
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