目的:血管血管造口术是逆转输精管切除术的一种经济有效的方法。为了获得更好的结果,需要水密的足够血液供应的粘膜吻合术。这篇综述旨在比较三种不同技术进行血管血管造口术的结果:宏观,纯显微外科手术,和机器人辅助的显微外科技术。
方法:Scopus,WebofScience,PubMed,Embase,从1901年1月至2023年6月,对Cochrane图书馆数据库进行了相关研究。我们使用OpenMeta软件中的逆方差方法进行了定量综合。该研究的协议已在PROSPERO上注册。
结果:这篇综述涉及95项不同设计的研究,总样本量为48,132。大多数手术是双边进行的,参与者被监测长达10年。合并的通畅率在机器人辅助血管造口术后最高(94.4%),其次是单纯的显微外科血管造口术(87.5%),和宏观血管造口术(83.7%)。纯显微外科血管造口术后的合并妊娠率高于宏观血管造口术(47.4vs.43.7%)。机器人血管造口术中的最终妊娠率尚未确定。
结论:使用机器人辅助的显微外科技术,血管血管造口术的通畅性最好,其次是纯显微外科技术,和传统的宏观技术。需要进一步研究机器人辅助的显微外科血管造口术的结果和随机对照试验来支持这一证据。
OBJECTIVE: Vasovasostomy is a cost-effective procedure for the reversal of vasectomy. A water-tight adequately blood-supplied mucosal anastomosis is required for better outcomes. This review aimed to compare the outcome of vasovasostomy performed by three different techniques:
macroscopic, pure microsurgical, and robot-assisted microsurgical techniques.
METHODS: Scopus, Web of Science, PubMed, Embase, and Cochrane library databases were searched for relevant studies from January 1901 to June 2023. We conducted our quantitative syntheses using the inverse variance method in OpenMeta software. The study\'s protocol was registered on PROSPERO.
RESULTS: This review involved 95 studies of different designs, with a total sample size of 48,132. The majority of operations were performed bilaterally, and participants were monitored for up to 10 years. The pooled patency rate was the highest following robot-assisted vasovasostomy (94.4%), followed by pure microsurgical vasovasostomy (87.5%), and
macroscopic vasovasostomy (83.7%). The pooled pregnancy rate following purely microsurgical vasovasostomy was higher than that of
macroscopic vasovasostomy (47.4 vs. 43.7%). Definitive pregnancy rates in robotic vasovasostomy are yet to be determined.
CONCLUSIONS: Patency outcomes for vasovasostomy were best with robot-assisted microsurgical technique, followed by pure microsurgical technique, and conventional
macroscopic technique. Further investigations of robot-assisted microsurgical vasovasostomy outcomes and randomized control trials are required to support this evidence.