背景:吃高质量的饮食或坚持给定的饮食策略可能会影响体重减轻。然而,对于大量营养素限制饮食后的患者,尚未同时检查这2个因素。
目的:为了确定饮食质量的改善是否,饮食中大量营养素组成的变化,当遵循健康的低碳水化合物(HLC)或健康的低脂肪(HLF)饮食时,这些因素的组合与不同的体重减轻有关。
方法:作为随机对照减肥研究的一部分,通常健康的成年人被随机分配到HLC或HLF饮食12个月(n=609)。在基线和12个月时具有完整的24小时饮食回忆数据的参与者被纳入本次二次分析(总N=448;N=224HLC,N=224HLF)。根据HEI-2010评分的12个月变化[中位数以上=高质量(HQ)和中位数以下=低质量(LQ)]和常量营养素摄入量的12个月变化[中位数以下=高依从性(HA)和中位数以上=低依从性(LA),对于HLC和HLF,分别]。比较了HQ/HA中平均BMI的基线到12个月的变化,总部/洛杉矶,LQ/HA亚群与LQ/LA亚群在HLC和HLF内。
结果:对于HLC,HQ/HA的平均BMI变化(95%置信水平[CI])为-1.15kg/m2(-2.04,-0.26),总部/洛杉矶-0.30(-1.22,0.61),与LQ/LA亚组相比,LQ/HA为-0.80(-1.74,0.14)。对于HLF来说,HQ/HA的平均BMI变化(95%CI)为-1.11kg/m2(-2.10,-0.11),总部/洛杉矶-0.26(-1.26,0.75),与LQ/LA亚组相比,LQ/HA为-0.66(-1.74,0.41)。
结论:在HLC和HLF饮食中,与LQ/LA亚组相比,HQ/HA亚组的12个月BMI下降幅度明显更大。单独的HQ和HA均与LQ/LA亚组无显著差异。该分析的结果支持饮食依从性和高质量饮食相结合以减轻体重。
背景:clinicaltrials.gov(标识符:NCT01826591)。
Eating a high-quality diet or adhering to a given dietary strategy may influence weight loss. However, these 2 factors have not been examined concurrently for those following macronutrient-limiting diets.
To determine whether improvement in dietary quality, change in dietary macronutrient composition, or the combination of these factors is associated with differential weight loss when following a healthy low-carbohydrate (HLC) or healthy low-fat (HLF) diet.
Generally healthy adults were randomly assigned to HLC or HLF diets for 12 mo (n = 609) as part of a randomized controlled weight loss study. Participants with complete 24-h dietary recall data at baseline and 12-mo were included in this secondary analysis (total N = 448; N = 224 HLC, N = 224 HLF). Participants were divided into 4 subgroups according to 12-mo change in HEI-2010 score [above median = high quality (HQ) and below median = low quality (LQ)] and 12-mo change in macronutrient intake [below median = high adherence (HA) and above median = low adherence (LA) for net carbohydrate (g) or fat (g) for HLC and HLF, respectively]. Baseline to 12-mo changes in mean BMI were compared for those in HQ/HA, HQ/LA, LQ/HA subgroups with the LQ/LA subgroup within HLC and HLF.
For HLC, changes (95 % confidence level [CI]) in mean BMI were -1.15 kg/m2 (-2.04, -0.26) for HQ/HA, -0.30 (-1.22, 0.61) for HQ/LA, and -0.80 (-1.74, 0.14) for LQ/HA compared with the LQ/LA subgroup. For HLF, changes (95% CI) in mean BMI were -1.11kg/m2 (-2.10, -0.11) for HQ/HA, -0.26 (-1.26, 0.75) for HQ/LA, and -0.66 (-1.74, 0.41) for LQ/HA compared with the LQ/LA subgroup.
Within both HLC and HLF diet arms, 12-mo decrease in BMI was significantly greater in HQ/HA subgroups relative to LQ/LA subgroups. Neither HQ nor HA alone were significantly different than LQ/LA subgroups. Results of this analysis support the combination of dietary adherence and high-quality diets for weight loss.
clinicaltrials.gov (Identifier: NCT01826591).