■肥胖是一种全球性的健康危机,对各种身体系统有着深远的影响。导致一系列合并症。代谢减重手术(MBS)已成为严重肥胖的有效治疗选择,具有显著的体重减轻和潜在的全身生理改变。
■这篇叙述性综述旨在全面分析MBS对广泛的身体系统的长期影响,包括心脏,肝脏,肾脏,生殖系统,皮肤,肺,消化道,胰腺,和血,以及这些器官的相关癌症。
■在学术数据库中进行了系统搜索(PubMed,ISIWebofScience,和Scopus),用于2000年7月至2023年12月之间发表的观察性研究和评论,调查MBS与随后的不同器官系统功能之间的关联。优先考虑高质量的研究,以确保可靠的证据综合。
■MBS在降低心血管疾病风险方面表现出良好的结果,改善心脏功能,缓解心力衰竭症状.它还与改善呼吸功能有关,缓解阻塞性睡眠呼吸暂停,降低癌症发病率和死亡率。此外,MBS在治疗胃肠道疾病方面显示出益处,加强血糖控制,促进2型糖尿病患者胰岛β细胞再生。然而,MBS的某些方法与胆石症的高风险有关,GERD,胰腺外分泌功能不全.
■MBS除了减肥外还具有深远的全身效应,为各种器官系统和与肥胖相关的合并症提供潜在的长期益处。对于许多严重肥胖的患者来说,代谢和减重手术(MBS)的潜在益处可能超过相关风险.然而,合格的医疗保健专业人员的仔细评估对于确定候选人资格和确保成功的结果至关重要。需要进一步的研究来充分阐明长期影响并定制个性化治疗方法。
UNASSIGNED: Obesity is a global health crisis with profound implications on various body systems, contributing to a series of comorbidities. Metabolic Bariatric Surgery (MBS) has emerged as an effective treatment option for severe obesity, with significant weight reduction and potential systemic physiological alterations.
UNASSIGNED: This narrative review aims to provide a comprehensive analysis of the long-term effects of MBS on a wide array of body systems, including the heart, liver, kidneys, reproductive system, skin, lungs, digestive tract, pancreas, and blood, as well as related cancers of these organs.
UNASSIGNED: A systematic search was conducted in academic databases (PubMed, ISI Web of Science, and Scopus) for observational studies and reviews published between July 2000 and December 2023, investigating the association between MBS and the subsequent function of different organ systems. High-quality studies were prioritized to ensure reliable evidence synthesis.
UNASSIGNED: MBS has demonstrated favorable outcomes in reducing cardiovascular disease risk, improving cardiac function, and alleviating heart failure symptoms. It has also been associated with improved respiratory function, remission of obstructive sleep apnea, and reduced cancer incidence and mortality. Additionally, MBS has shown benefits in managing gastrointestinal disorders, enhancing glycemic control, and promoting pancreatic beta-cell regeneration in type 2 diabetes mellitus. However, some methods of MBS are associated with a higher risk of cholelithiasis, GERD, and pancreatic exocrine insufficiency.
UNASSIGNED: MBS has far-reaching systemic effects beyond weight loss, offering potential long-term benefits for various organ systems and comorbidities associated with obesity. For many patients with severe obesity, the potential benefits of Metabolic and Bariatric Surgery (MBS) can outweigh the associated risks. However, careful evaluation by a qualified healthcare professional is crucial to determine candidacy and ensure a successful outcome. Further research is needed to fully elucidate the long-term impacts and tailor personalized treatment approaches.