Jewelry

珠宝
  • 文章类型: Journal Article
    由于潜在的细菌积累和传播,在医疗保健专业人员中使用珠宝会带来交叉污染的风险。通过混合方法设计,这项研究首先分析了医疗保健专业人员佩戴珠宝对患者护理生物安全以及手部卫生后手部和戒指残留细菌负荷的影响。首先,我们进行了一项观察性患病率研究,以验证护理专业人员在医疗救助期间是否佩戴个人配饰.第二,涉及手的有意污染和卫生的实验设计,有和没有戒指,进行了。通过计数菌落形成单位来测量双手和戒指的细菌负荷。观察性研究表明,护理人员在医疗援助期间经常佩戴珠宝。尽管如此,实验研究没有表明有和没有戒指的手之间细菌污染的差异,尽管采用了手部卫生程序。总之,许多护理人员在工作场所佩戴珠宝。尽管有和没有戒指的手表现出相似的微生物负荷,环是细菌污染的潜在来源,加强在工作时间内移除珠宝的需要。使用酒精的手部卫生,或者肥皂和水显著减少了参与者手上的细菌负荷,洗手被证明是去除故意污染的最有效方法。
    The use of jewelry among healthcare professionals poses a risk of cross contamination due to potential bacterial accumulation and spread. Through a mixed-method design, this study first analyzed the implications of healthcare professionals wearing jewelry on patient care biosafety as well as on the residual bacterial load of hands and rings after hand hygiene. Firstly, an observational prevalence study to verify whether nursing professionals wear personal accessories during healthcare assistance was carried out. Second, an experimental design involving intentional contamination and hygiene of the hands, with and without a ring, was conducted. The bacterial load of both hands and rings was measured by counting colony forming units. The observational study showed that nursing workers frequently wear jewelry during healthcare assistance. Nonetheless, the experimental study did not indicate differences in bacterial contamination between hands with and without a ring, despite the hand hygiene procedure applied. In conclusion, many nursing workers wear jewelry in the workplace. Although hands with and without a ring exhibited similar microbial load, rings appeared as a potential source of bacterial contamination, reinforcing the need to remove jewelry during working hours. Hand hygiene using alcohol, or soap and water significantly decreased the bacterial load on the participants\' hands, with handwashing proving to be the most efficient method for removing intentional contamination.
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  • 文章类型: Historical Article
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  • 文章类型: Journal Article
    方法:一名41岁的男子通过用高速金属毛刺将其切掉,从左手食指上取下了一个碳化钨戒指。两天后,患者出现粉红色和灌注的左食指,环区域周围有干性坏疽,活动屈伸肌腱偏移,远端感觉下降。24小时内,伤口发展为湿性坏疽和弥漫性紫癜,需要截肢。
    结论:在回顾了以前记录的去除碳化钨环的方法之后,作者认为,临床医生应该认识到与使用高速金属毛刺相关的潜在并发症.
    METHODS: A 41-year-old man removed a tungsten carbide ring from his left index finger by cutting it off with a high-speed metal burr. The patient presented two days later with a pink and perfused left index finger with circumferential dry gangrene along the area of the ring, active flexor and extensor tendon excursion, and decreased sensation distally. Within 24 hours, the wound developed into wet gangrene and diffuse cyanosis requiring amputation.
    CONCLUSIONS: After reviewing previously documented methods to remove tungsten carbide rings, the authors conclude clinicians should be cognizant of the potential complications associated with the use of a high-speed metal burr.
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  • 文章类型: Case Reports
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  • 文章类型: Journal Article
    氨基酸表面活性剂在克服常规表面活性剂的局限性方面具有重要意义。特别是,它们的生物相容性和生物降解性低。然而,目前的氨基酸表面活性剂由于其脂族链的非反应性而缺乏多功能特性,有必要开发一种新型的氨基酸表面活性剂。通过模拟黑色素的生物合成,设计了一种新型的黑色素样氨基酸表面活性剂和仿生合成路线。具有邻苯二酚部分的可再生天然多酚化合物被用作疏水基团的结构单元。在概念验证实验中,原儿茶酸乙酯被氧化为邻醌,随后通过Michael加成与赖氨酸的氨基共价连接。使用液相色谱-串联质谱法验证化学结构。黑色素样氨基酸表面活性剂表现出优异的表面活性,临界胶束浓度为1.59mNm-1。此外,它表现出显著的乳化作用,发泡,增溶,分散,和润湿能力。值得注意的是,它还具有多功能性,包括抗菌活性,抗氧化活性,鲁棒性,和温和。这些突出的性能表明了各种应用的巨大潜力。这一战略提供了创新的见解和多才多艺的,用于合成模拟黑色素的多功能氨基酸表面活性剂的模块化工具箱。该方法允许邻醌结构单元的轻松互换,类似于折断珠宝。
    Amino acid surfactants have gained significant importance in overcoming the limitations of conventional surfactants, notably, their low biocompatibility and biodegradability. However, the current amino acid surfactants lack multifunctional properties due to the nonreactivity of their aliphatic chains, necessitating the development of a new type of amino acid surfactant. A novel melanin-like amino acid surfactant and a biomimetic synthesis route were devised by mimicking the biosynthesis of melanin. Renewable natural polyphenol compounds with catechol moieties were utilized as building blocks for the hydrophobic group. In a proof-of-concept experiment, ethyl protocatechuate was oxidized to o-quinone and subsequently covalently linked to the amino group of lysine via Michael addition. The chemical structure was verified using liquid chromatography-tandem mass spectroscopy. The melanin-like amino acid surfactant exhibited excellent surface-active properties, with a critical micelle concentration of 1.59 mN m-1. Furthermore, it demonstrated remarkable emulsifying, foaming, solubilizing, dispersing, and wetting capabilities. Notably, it also possessed multifunctionality, including antibacterial activity, antioxidant activity, robustness, and mildness. These outstanding properties indicate significant potential for various applications. This strategy offers innovative insights and a versatile, modular toolbox for synthesizing multifunctional amino acid surfactants that mimic melanin. The approach allows for the easy interchange of o-quinone building blocks, which is akin to snap jewelry.
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  • 文章类型: Journal Article
    本文重点介绍了中国电子商务平台(((n=8))带有重金属杂质(Pb,Cd和Hg)及其对人类健康和环境的潜在影响。该研究强调了使用便携式X射线荧光(pXRF)分析快速,非破坏性的,以及珠宝中重金属的原位分析。结果表明,所有产品(n=106)含有不同水平的重金属,汞是最常见的重金属。71%的样品超过了欧盟的Pb限值,51%的样品超过了欧盟的Cd限值,这一事实令人震惊,并强调需要对珠宝行业进行更严格的法规和监控,以减轻重金属在环境中带来的风险。该研究强调了使用pXRF分析来识别珠宝中的重金属的重要性,并解决了Pb环境风险评估中的文献空白。Cd,和汞在中国成人的低成本珠宝中。总的来说,调查结果呼吁采取紧急行动,通过加强法规和监测珠宝行业来确保消费者的安全和防止环境污染。
    This article focusses on the environmental implications of low-cost jewelry for adults from Chinese e-commerce platforms ((n = 8) with heavy metal impurities (Pb, Cd and Hg) and their potential impact on human health and the environment. The study highlights the advantages of using portable X-ray fluorescence (pXRF) analysis for rapid, non-destructive, and in situ analysis of heavy metals in jewelry. The results reveal that all products (n = 106) contained heavy metals at varying levels, Hg being the most commonly detected heavy metal. The fact that 71% of the samples exceeded the EU limit for Pb and 51% exceeded the EU limit for Cd is alarming and highlights the need for stricter regulations and monitoring of the jewelry industry to mitigate the risks posed by heavy metals in the environment. The study emphasizes the importance of using pXRF analysis to identify heavy metals in jewelry and address the literature gap in environmental risk assessments of Pb, Cd, and Hg in low-cost jewelry for adults from China. In general, the findings call for urgent action to ensure the safety of consumers and prevent environmental pollution by strengthening regulations and monitoring the jewelry industry.
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  • 文章类型: Letter
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  • 文章类型: Journal Article
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  • 文章类型: Journal Article
    全球范围内,儿童用品中的有害物质是非常值得关注的。有毒化学物质可能对婴儿和儿童的健康和成长有害。铅(Pb)和镉(Cd)污染的儿童珠宝在许多国家都被广泛遇到。本研究旨在确定金属毒物的浓度(Pb,Cd,Ni,Cu,Zn,Co,和Fe)在基于事件的(独立日节日)儿童珠宝中,考虑有时间限制和快速生产的产品,这些产品可能会在制造过程中损害质量和安全参数。这些决定是针对在各种基础材料中使用的有毒物质的背景下儿童珠宝的时间限制工业生产。这是首次对基于事件的儿童珠宝进行监测,并对金属污染进行严格评估。42个样本,包括金属,木制的,纺织品,橡胶,塑料,和涂有油漆的塑料儿童珠宝,进行了测试。74%的样品检测到可量化的Pb和Cd。Ni在71%,铜含量为67%,公司占43%,在100%的样品中以可量化的量检测到Zn和Fe。22个ID-CJ样品超过了美国的Pb法规限值,4个样品超过了Cd法规限值。然而,29个铅样品,11张CD,五个公司,其中一个铜超过了欧盟的监管限制。在涂有油漆的塑料珠宝中发现了最高的Pb浓度,最高的镉是在金属珠宝中发现的。这些结果表明,基于事件的儿童珠宝的潜在危害值得政府机构关注,以限制儿童接触有毒化学物质。政府间组织和个别国家管理消费品中的化学品,但是缺乏协调的国际方法。一些大陆和国家仍然缺乏儿童产品的法规,尤其是珠宝,和玩具。
    Globally, the hazardous substance in children\'s goods is of great concern. Toxic chemicals are potentially harmful to the health and growth of infants and children. Lead (Pb) and cadmium (Cd)-contaminated children\'s jewelry is widely encountered in many countries. This study aims to determine the concentration of metal toxicants (Pb, Cd, Ni, Cu, Zn, Co, and Fe) in event-based (Independence Day festival) children\'s jewelry, considering time-limited and fast production products that may compromise the quality and safety parameters during manufacturing. The determinations are for the time-constraint industrial production of children\'s jewelry in the context of the toxic substances in a variety of base materials used. This is the first time event-based children\'s jewelry has been monitored and critically assessed for metal contamination. Forty-two samples, including metallic, wooden, textile, rubber, plastic, and paint-coated plastic children\'s jewelry, were tested. Seventy-four percent of samples detected Pb and Cd in quantifiable amounts. Ni in 71%, Cu in 67%, Co in 43%, and Zn and Fe were detected in 100% samples with quantifiable amounts. Twenty-two ID-CJ samples exceeded the US regulatory limit for Pb and four samples for Cd. However, twenty-nine samples for Pb, eleven for Cd, five for Co, and one for Cu exceeded the EU regulatory limit. The highest concentration of Pb was found in paint-coated plastic jewelry, and the highest Cd was found in metallic jewelry. These results suggest that the potential hazards of event-based children\'s jewelry deserve the attention of government agencies seeking to limit children\'s exposure to toxic chemicals. Intergovernmental organizations and individual countries regulate chemicals in consumer products, but a coordinated international approach is lacking. Some continents and countries still lack in regulations for children\'s products, especially jewelry, and toys.
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  • 文章类型: Editorial
    从珠宝和硬币到抗癌和抗病毒剂,特殊的“软”字符以及物理化学,金的氧化还原和配体交换性质可以用来设计新的生物活性配合物,这可能为治疗和诊断应用药物的开发开辟新的视角。
    从珠宝和硬币到抗癌和抗病毒剂,独特的“软”特征以及物理化学特征,金的氧化还原和配体交换性质可以用来设计新的生物活性配合物,这可能为治疗和诊断应用药物的开发开辟新的视角。
    Plain language summary From jewels and coinage to anticancer and antiviral agents, the peculiar \'soft\' character as well as physicochemical, redox and ligand exchange properties of gold can be exploited to design novel bioactive complexes, which may open up new perspectives to the development of drugs for therapeutic and diagnostic applications.
    From jewels and coinage to anticancer and antiviral agents, the peculiar ‘soft’ character as well as physicochemical, redox and ligand exchange properties of gold can be exploited to design novel bioactive complexes, which may open up new perspectives to the development of drugs for therapeutic and diagnostic applications.
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