Intestinal Perforation

肠穿孔
  • 文章类型: Case Reports
    在过去的两个月中,一名70多岁的男性因胸腹动脉瘤而有人工血管置换史,因粘连性肠梗阻接受了非手术治疗。最初的症状是恶心,患者因为弥漫性腹痛被转移到我们医院。计算机断层扫描显示气胸,膈疝,肠穿孔.插入左胸腔引流管,并排出空气和清澈的黄色液体。继发性气胸可能是由与膈疝相关的肠穿孔引起的。尽管报道的继发气胸与膈疝和肠穿孔相关的病例是由创伤引起的,这种并发症可在术后发生。
    A male in his 70s with a history of artificial vessel replacement for a thoracoabdominal aneurysm had been treated non-operatively for adhesive bowel obstruction during the past two months. The initial symptom was nausea and the patient was transferred to our hospital because of diffuse abdominal pain. Computed tomography revealed pneumothorax, diaphragmatic hernia, and bowel perforation. A left thoracic drain was inserted and air and clear yellow fluid were drained. Secondary pneumothorax was presumably caused by intestinal perforation associated with diaphragmatic hernia. Although reported cases with secondary pneumothorax associated with diaphragmatic hernia and intestinal perforation are caused by trauma, this complication can occur postoperatively.
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  • 文章类型: Case Reports
    年龄较小的儿童经常摄入异物,保守管理总体上有很好的结果。然而,磁珠摄入是年龄较大的儿童肠穿孔的特殊原因。
    方法:一名8岁男孩出现全身性急性腹膜炎的临床症状。腹部X线平片证实了消化道中的异物,并通过突出显示几种气液水平来确定病因,扩张的小肠环,气腹和在第5腰椎附近突出的双叶异物的存在。进行了开放性手术探查,发现腹膜液,小肠中的2个穿孔和2个粘附的磁铁。回肠切除20厘米,包括带有2个穿孔的段,进行了末端回肠造口术。16天后进行胃肠连续性的恢复。经过2年零8个月的随访,患者没有任何症状。
    在穿孔引起急性腹膜炎的病例中,一般情况逐渐恶化。发烧可能缺席,我们的病人也是如此.腹痛是主要症状,它通常伴有呕吐,可以是消化道,胆汁,或者甚至是类粪便和/或通过停止排便和/或气体。腹部僵硬是一个主要的体征,有时被广义的守卫所取代。
    结论:消化道异物在年龄较大的儿童中很少见,一个以上的磁铁的存在会导致腹膜炎由于肠穿孔。
    UNASSIGNED: Foreign body ingestion is frequent in younger children, with generally good outcome on conservative management. However, magnetic beads ingestion is an exceptional cause of intestinal perforation in the older children.
    METHODS: An 8-year-old boy presented with clinical signs of generalized acute peritonitis. Abdominal plain X-ray confirmed the foreign object in the digestive tract and oriented the etiology by highlighting several air-fluid levels, distended small bowel loops, pneumoperitoneum and the presence of a bilobed foreign body projected adjacent to the 5th lumbar vertebra. Open surgical exploration was performed and revealed a peritoneal fluid, 2 perforations in the small bowel and 2 adhered pieces of magnets. A 20 cm ileal resection, including the segment with the 2 perforations, was performed followed by a terminal ileostomy. The restoration of gastrointestinal continuity was performed 16 days later. After a follow-up of 2 years and 8 months, the patient was free of any symptom.
    UNASSIGNED: In cases of acute peritonitis due to perforation, the general condition deteriorates progressively. Fever may be absent, as was the case with our patient. Abdominal pain is the predominant symptom, it is often accompanied by vomiting that can be alimentary, bilious, or even fecaloid and/or by cessation of bowel movements and/or gas. Abdominal rigidity is a major physical sign, sometimes replaced by generalized guarding.
    CONCLUSIONS: Ingestion of gastrointestinal foreign bodies is rare in older children, the presence of more than one magnet can lead to peritonitis due to intestinal perforation.
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  • 文章类型: Journal Article
    背景:Meckel憩室(MD)是胃肠道最常见的先天性异常。然而,MD在临床实践中很少见,异物对MD的穿孔甚至更罕见。术前诊断很困难,因为通常信息不足;因此通常在术中诊断。虽然罕见,应将其视为摄入异物的患者的鉴别诊断。
    方法:以下是一名52岁女性患者,因全身腹痛而入院5天,与恶心和呕吐有关。她也停止了加油。炎症指标升高,计算机断层扫描(CT)显示小肠中的气液水平和回肠中的高密度物体。根据病人的情况,由于腹腔镜手术难以进行,因此进行了剖腹手术。术中,回肠末端憩室有异物穿孔,导致腹部脓肿的发展。最后,我们进行了回肠憩室切除和回肠部分切除。手术后,证实异物是病人不小心吃掉的两个假牙。
    结论:对临床表现有透彻的了解,成像特征,和治疗MD及其并发症将有助于临床医生做出及时准确的诊断并提供对症治疗。
    BACKGROUND: Meckel\'s diverticulum (MD) is the most common congenital abnormality of the gastrointestinal tract. However, MD is rare in clinical practice, and perforation of a MD by a foreign body is even rarer. Preoperative diagnosis is difficult because there is often insufficient information; therefore it is usually diagnosed intraoperatively. Although rare, it should be considered as a differential diagnosis in patients who have ingested foreign bodies.
    METHODS: The following is the case of a 52-year-old female patient who was admitted because of generalized abdominal pain for 5 days, related to nausea and vomiting. She also stopped passing gas. Inflammatory indicators were elevated, and computed tomography (CT) revealed gas-liquid levels in the small intestine and high-density objects in the ileum. Based on the patient\'s condition, laparotomy was performed instead because the laparoscopic procedure was difficult to perform. Intraoperatively, a foreign body perforated the diverticulum of the terminal ileum, resulting in the development of an abdominal abscess. Finally, we performed resection of the ileal diverticula and partial resection of the ileum. After the surgery, it was confirmed that the foreign bodies were two dentures accidentally eaten by the patient.
    CONCLUSIONS: A thorough understanding of the clinical presentation, imaging features, and treatment of MD and its complications will assist clinicians in making prompt and accurate diagnoses and providing symptomatic treatment.
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  • 文章类型: Case Reports
    这是一例70岁女性可能患有胆甾胺引起的肠穿孔的病例报告。她有胰腺癌胰十二指肠切除术史,每天摄入胆甾胺。她接受了两次小肠穿孔的紧急剖腹手术。随后的病理报告显示小肠壁中有晶体沉积。在第二次手术期间,在小肠和网膜上扩散的裂隙被认为是癌变。然而,病理报告显示,没有恶性细胞,但有大量晶体沉积,如摄入胆甾胺。
    This is a case report of a 70-year-old woman with possible cholestyramine-induced bowel perforation. She had a prior history of pancreaticoduodenectomy for pancreatic cancer with a daily intake of cholestyramine. She underwent emergency laparotomy for small bowel perforation twice. Subsequent pathology reports showed crystal depositions in the small bowel wall. Leasions spread out on the small bowel and the omentum during the second surgery were thought to be carcinomatosis. However, the pathology report showed no malignant cells but plenty of crystal depositions as seen with cholestyramine intake.
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  • 文章类型: Journal Article
    背景肠穿孔是一种危及生命的疾病,需要立即手术干预。手术部位感染(SSIs)和伤口裂开是与紧急剖腹手术治疗肠穿孔相关的常见并发症。找到最佳的伤口管理和术后策略可以显着影响患者的预后并降低并发症的风险。负压伤口治疗(NPWT)是一种相对较新的工具,用于伤口护理以控制SSI并促进愈合。方法论A前瞻性,观察,本研究对2022年7月至2023年12月在新德里一家三级医院普外科因肠穿孔行紧急剖腹探查术的150例患者进行了队列研究.术前,所有患者均接受了初步复苏.术中,根据疾病控制和预防中心(CDC)的分类,确定腹膜炎的程度并进行分类.术后,术后第2天(POD)将NPWT敷料应用于患者的中线剖腹伤口。负压设定在75-125mmHg的抽吸。记录所需的NPWT敷料更换次数。在局部麻醉下用垂直床垫缝线闭合伤口,延迟初级闭合(DPC)。SSIs的发生率,DPC的持续时间,筋膜裂开的发生率,NPWT敷料更换的次数,根据CDC组记录住院时间.结果CDC第2、3和4类的平均年龄分别为31.789、28.733和42.676岁,分别。穿孔的最常见原因是肠热(n=42,28%),其次是肺结核(n=36,24%)。大多数患者没有已知的合并症(n=80,53.3%)。总的来说,16%的患者(n=24)既酗酒又吸烟。所有CDC类别中最常见的细菌是大肠杆菌。14例患者在术后发生腹部爆裂,被排除在研究之外。DPC的平均持续时间随着CDC类别的增加而增加,CDC类别4显示最长的平均持续时间为10.70天。NPWT敷料更换的数量随着CDC类别的增加而增加,CDC第4类表现出最高的平均值,为2.00变化。平均住院时间随着CDC类别的增加而增加,CDC第4类显示平均停留时间最长,为17.324天。统计分析显示,SSI发生率与CDC类别之间没有显着关联。结论NPWT和DPC是一种很有前途的治疗胃肠道穿孔的方法。减少SSI,并有可能改善患者的预后。然而,需要进一步的研究来探索NPWT联合DPC的具体益处及其在各种临床方案中的疗效.
    Background Intestinal perforation is a life-threatening condition requiring immediate surgical intervention. Surgical-site infections (SSIs) and wound dehiscence are common complications associated with emergency laparotomy for intestinal perforation. Finding optimal wound management and postoperative strategies can significantly impact patient outcomes and reduce the risk of complications. Negative-pressure wound therapy (NPWT) is a relatively recent tool employed in the care of wounds to control SSIs and foster healing. Methodology A prospective, observational, cohort study was conducted among 150 patients who underwent emergency exploratory laparotomy due to intestinal perforation at the general surgery department of a tertiary care hospital in New Delhi between July 2022 and December 2023. Preoperatively, all patients underwent initial resuscitation. Intraoperatively, the extent of peritonitis was determined and was categorized according to the Centers for Disease Control and Prevention (CDC) classification. Postoperatively, NPWT dressing was applied to the patient\'s midline laparotomy wound on postoperative day (POD) two. Negative pressure was set at 75-125 mmHg with suction. The number of NPWT dressing changes required was documented. The wound was closed with vertical mattress sutures under local anesthesia, delayed primary closure (DPC). The incidence of SSIs, the duration for DPC, the incidence of fascial dehiscence, the number of NPWT dressing changes, and the length of hospital stay were documented according to CDC groups. Results The mean age in CDC categories 2, 3, and 4 were 31.789, 28.733, and 42.676 years, respectively. The most common cause of perforation was enteric fever (n = 42, 28%), followed by tuberculosis (n = 36, 24%). Most patients had no known comorbidities (n = 80, 53.3%). Overall, 16% of patients (n = 24) were both alcoholics and smokers. The most frequent bacteria in all CDC categories was Escherichia coli. Fourteen patients developed burst abdomen in the postoperative period and were excluded from the study. The mean duration of DPC increased with higher CDC categories, with CDC category 4 displaying the most extended mean duration at 10.70 days. The number of NPWT dressing changes increases with higher CDC categories, with CDC category 4 exhibiting the highest mean at 2.00 changes. The mean hospital stay increased with higher CDC categories, with CDC category 4 showing the most extended mean stay at 17.324 days. Statistical analysis revealed no significant association between SSI occurrence and CDC categories. Conclusions NPWT followed by DPC is a promising approach to managing gastrointestinal perforations, reducing SSIs, and potentially improving patient outcomes. However, further research is needed to explore the specific benefits of NPWT in conjunction with DPC and its efficacy in various clinical scenarios.
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  • 文章类型: Case Reports
    一个病例描述了一名49岁的男性患者,该患者因小肠穿孔而接受了紧急剖腹手术。由于空肠肿瘤穿孔而存在腹膜炎。切除空肠肿瘤并穿孔,然后对空肠进行端到端吻合。切除的空肠肿瘤在组织病理学检查中被鉴定为转移性肺鳞状细胞/大细胞癌的透明细胞变体。它与大脑中的转移性病变有关。空肠肺癌转移是一种非常罕见的疾病,易导致小肠穿孔,这也与脑转移有关。
    A case describes a 49-year-old male patient who underwent emergency exploratory laparotomy for small intestinal perforation. Peritonitis was present due to perforation of the jejunal tumor. Resection of the jejunal tumor with perforation was performed followed by end-to-end anastomosis of the jejunum. The resected jejunal tumor was identified in the histopathological examination as metastatic from a clear cell variant of squamous cell/large cell carcinoma of the lung. It was associated with metastatic lesions in the brain. Metastasis from the lung carcinoma in the jejunum is a very rare condition predisposing to small intestinal perforation which is also associated with brain metastasis.
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  • 文章类型: Case Reports
    尽管器官移植具有显著的存活率和成本效益,术后并发症仍然存在。胃肠道并发症,包括那些涉及胃和肠的,占移植后并发症的1-6%,特别是肠穿孔约占9%,取决于中心。在越南,没有关于这些并发症的全面报告。因此,我们报告了3例移植后胃肠道穿孔的临床病例。在此病例系列中描述了三例肠穿孔。2023年,一名因先天性心脏病而接受心脏移植的16岁女性患者在第12天被诊断为肠穿孔。患者在手术后需要持续的血液过滤支持。2018年,肝移植后六天,一名56岁的男性患者被诊断为肠穿孔,随后被修复,他的肠子末端被切除了.患者30天后病情稳定出院。2017年,肾移植后五天,一名46岁的女性患者被诊断为肠穿孔,修复了,穿孔部位保持开放。患者在40天后病情稳定出院。肠穿孔是比较少见的,但并不少见,并发症。由于非特异性临床症状和体征,早期诊断具有挑战性。考虑到肠穿孔的可能性并获得早期腹部计算机断层扫描成像可以帮助防止延迟诊断。
    Although organ transplantation is associated with significant survival rates and cost benefits, postoperative complications still occur. Gastrointestinal complications, including those involving the stomach and intestines, account for 1-6% of posttransplant complications, with intestinal perforation specifically accounting for approximately 9%, depending on the center. In Vietnam, there are no comprehensive reports on these complications. Therefore, we report three clinical cases of gastrointestinal perforation following transplantation. Three cases of intestinal perforation are described in this case series. In 2023, a 16-year-old female patient who underwent heart transplantation for congenital heart disease was diagnosed with intestinal perforation on the 12th day. The patient required continued blood filtration support after surgery. In 2018, six days after liver transplantation, a 56-year-old male patient was diagnosed with intestinal perforation, which was subsequently repaired, and the ends of his intestines were removed. The patient was discharged in stable condition after 30 days. In 2017, five days after kidney transplantation, a 46-year-old female patient was diagnosed with intestinal perforation, which was repaired, and the perforation site was left open. The patient was discharged in stable condition after 40 days. Intestinal perforation is a relatively rare, but not uncommon, complication. Early diagnosis is challenging due to nonspecific clinical symptoms and signs. Considering the possibility of intestinal perforation and obtaining early abdominal computed tomography imaging can help prevent delayed diagnosis.
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  • 文章类型: Case Reports
    此病例报告概述了31岁女性激光痔成形术后直肠穿孔的复杂处理,导致急腹症,脓毒症,多器官衰竭。进行了紧急的腹腔镜探查和双回路结肠造口术的建立。标志着以复发性盆腔败血症为特征的复杂病程的开始。激光痔成形术因其在治疗痔疮方面的微创方法而获得了广泛的接受。值得注意的是,根据我们的知识,我们介绍的病例是激光痔成形术后报告的第一个主要并发症,可能归因于附带的热和机械组织损伤。
    This case report outlines the intricate management of rectal perforation following laser hemorrhoidoplasty in a 31-year-old female, leading to an acute abdomen, sepsis, and multiorgan failure. Urgent laparoscopic exploration and the establishment of a double-loop colostomy were undertaken, marking the beginning of a complex course characterized by relapsed pelvic sepsis. Laser hemorrhoidoplasty has gained widespread acceptance for its minimally invasive approach in treating hemorrhoids. Remarkably, to our knowledge, the case we present is the first major complication reported after laser hemorrhoidoplasty, likely attributed to collateral thermic and mechanical tissue damage.
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  • 文章类型: Journal Article
    背景:我们的目的是描述为处理结肠镜相关穿孔而进行的手术干预的临床结果,并将这些结果与在择期和急诊环境中进行的匹配结直肠手术的结果进行比较。
    方法:我们纳入了2014-2017年国家手术质量改进计划中接受手术干预的内镜下结肠穿孔患者,参与者使用数据结肠直肠靶向程序文件。这项研究的主要结果是短期手术发病率和死亡率。在选择性(第2组)或急诊(第3组)的基础上,患者(第1组)与接受相同手术干预以其他适应症的对照组患者的比例为1:2。进行了双变量分析,以比较三组之间的分类变量,多因素logistic回归用于评估手术指征与术后30天结局之间的相关性.
    结果:共纳入590例患者。患者的平均年龄为66.5±13.6,女性占主导地位(381,64.6%)。大多数患者进行了开腹结肠切除术(365,61.9%),其余患者进行了缝合(140,23.7%)和腹腔镜结肠切除术(85,14.4%)。总死亡率为4.1%,三种技术之间的死亡率无统计学差异(P=0.468)。163例患者发生复合发病率(27.6%)。腹腔镜结肠切除术(14.1%)明显低于开腹结肠切除术和缝合方法的30.2%和29.4%(P=0.014)。因医源性结肠穿孔而接受结肠切除术的患者死亡率较低,感染率和败血症,以及与紧急结肠切除术的患者相比的出血事件。前一组与接受其他适应症的择期结肠切除术的患者之间的结果具有可比性。
    结论:结肠镜检查相关穿孔的手术治疗是安全有效的,其结果与择期结肠切除术患者相似。
    BACKGROUND: Our aim was to describe the clinical outcomes of surgical interventions performed for the management of colonoscopy-related perforations and to compare these outcomes with those of matched colorectal surgeries performed in elective and emergency settings.
    METHODS: We included patients with endoscopic colonic perforation who underwent surgical intervention from the 2014-2017 National Surgery Quality Improvement Program participant use data colorectal targeted procedure file. The primary outcome in this study was short term surgical morbidity and mortality. Patients (group 1) were matched with 1:2 ratio to control patients undergoing same surgical interventions for other indications on an elective (group 2) or emergency basis (group 3). Bivariate analysis was conducted to compare categorical variables between the three groups, and multivariate logistic regression was used to evaluate the association between the surgical indication and 30-day postoperative outcomes.
    RESULTS: A total of 590 patients were included. The average age of the patients was 66.5±13.6 with female gender predominance (381, 64.6%) The majority of patients underwent open colectomy (365, 61.9%) while the rest had suturing (140, 23.7%) and laparoscopic colectomy (85, 14.4%). Overall mortality occurred in 4.1% and no statistically significant difference in mortality was found between the three techniques (P=0.468). Composite morbidity occurred in 163 patients (27.6%). It was significantly lower in laparoscopic colectomy (14.1%) compared to 30.2% and 29.4% in open colectomy and suturing approaches (P=0.014). Patients undergoing colectomy for iatrogenic colonic perforation had less mortality, infection rates and sepsis, as well as bleeding episodes compared to those who had colectomy on an emergent basis. Outcomes were comparable between the former group and patients undergoing elective colectomy for other indications.
    CONCLUSIONS: Surgical management of colonoscopy related perforations is safe and effective with outcomes that are similar to that of patients undergoing elective colectomy.
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  • 文章类型: Journal Article
    背景:由插入引流管引起的回肠穿孔是一种罕见的并发症。因此,在腹部手术中使用外科引流管仍存在争议。目前,在腹部手术中有减少引流管使用的趋势,尽管某些情况可能需要它们的应用。
    方法:一名25岁的中国女性,有右下腹痛持续10天的病史。影像学检查,包括腹部计算机断层扫描和超声检查,发现右下腹部10×8×8cm3的低密度病变,与穿孔性阑尾炎并发阑尾周围脓肿一致。进行了腹腔镜阑尾切除术。术后第5天,引流液变为草绿色(80mL)。通过引流管进行逆行对比成像显示,26Fr硅橡胶引流管尖端位于回肠内回肠连接处50cm处。回肠和回盲区都发育良好。
    结果:暂停口服摄入,病人接受了抗酸剂,生长抑素,抗生素,和全胃肠外营养。术后第19天,通过引流管使用逆行造影的随访成像程序显示导管尖端已密封.治疗在术后第33天结束,病人出院了.
    结论:腹腔镜阑尾切除术后由于腹腔引流管而导致的回肠穿孔是一种罕见但严重的并发症。然而,由于脓肿周围的粘连和炎症变化,腹腔镜解剖成为一个具有挑战性和风险的过程,手术技巧和经验尤为重要。建议根据引流液的特点及时取出腹腔引流管。这些发现为外科医生应对类似挑战提供了有价值的见解。
    BACKGROUND: Ileal perforation caused by the insertion of a drainage tube is a rare complication. Hence, the utilization of surgical drains in abdominal surgery remains controversial. At present, there is a trend to reduce the utilization of drains in abdominal surgery, although certain situations may necessitate their application.
    METHODS: A 25-year-old Chinese woman presented with a history of right lower abdominal pain persisting for 10 days. Imaging examinations, including abdominal computed tomography and ultrasound, identified low-density lesions measuring 10 × 8 × 8cm3 in the right lower abdomen, which are consistent with perforated appendicitis complicated by a peri-appendiceal abscess. A laparoscopic appendectomy was carried out. On the 5th postoperative day, the drainage fluid changed to a grass-green color (80mL). Imaging with retrograde contrast through the drainage tube revealed that the 26 Fr silicon rubber drainage tube tip was positioned 50cm away from the ileocecal junction within the ileum. Both the ileal and ileocecal regions appeared well-developed.
    RESULTS: Oral intake was suspended, and the patient received antacids, somatostatin, antibiotics, and total parenteral nutrition. On the 19th postoperative day, a follow-up imaging procedure using retrograde contrast through the drainage tube indicated that the tube tip was sealed. The treatment concluded on day 33 postoperatively, and the patient was discharged.
    CONCLUSIONS: Ileal perforation due to an abdominal drainage tube following laparoscopic appendectomy constitutes a rare but serious complication. However, due to the adhesion and inflammatory changes around the abscess, laparoscopic dissection becomes a challenging and risky process, and the surgical skills and experiences are particularly important. Removing the abdominal drainage tube promptly based on the characteristics of the drainage fluid is recommended. The findings provide valuable insights for surgeons navigating similar challenges.
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