关键词: acute peritonitis case series gastrointestinal complications intestinal perforation solid organ transplant

来  源:   DOI:10.7759/cureus.59977   PDF(Pubmed)

Abstract:
Although organ transplantation is associated with significant survival rates and cost benefits, postoperative complications still occur. Gastrointestinal complications, including those involving the stomach and intestines, account for 1-6% of posttransplant complications, with intestinal perforation specifically accounting for approximately 9%, depending on the center. In Vietnam, there are no comprehensive reports on these complications. Therefore, we report three clinical cases of gastrointestinal perforation following transplantation. Three cases of intestinal perforation are described in this case series. In 2023, a 16-year-old female patient who underwent heart transplantation for congenital heart disease was diagnosed with intestinal perforation on the 12th day. The patient required continued blood filtration support after surgery. In 2018, six days after liver transplantation, a 56-year-old male patient was diagnosed with intestinal perforation, which was subsequently repaired, and the ends of his intestines were removed. The patient was discharged in stable condition after 30 days. In 2017, five days after kidney transplantation, a 46-year-old female patient was diagnosed with intestinal perforation, which was repaired, and the perforation site was left open. The patient was discharged in stable condition after 40 days. Intestinal perforation is a relatively rare, but not uncommon, complication. Early diagnosis is challenging due to nonspecific clinical symptoms and signs. Considering the possibility of intestinal perforation and obtaining early abdominal computed tomography imaging can help prevent delayed diagnosis.
摘要:
尽管器官移植具有显著的存活率和成本效益,术后并发症仍然存在。胃肠道并发症,包括那些涉及胃和肠的,占移植后并发症的1-6%,特别是肠穿孔约占9%,取决于中心。在越南,没有关于这些并发症的全面报告。因此,我们报告了3例移植后胃肠道穿孔的临床病例。在此病例系列中描述了三例肠穿孔。2023年,一名因先天性心脏病而接受心脏移植的16岁女性患者在第12天被诊断为肠穿孔。患者在手术后需要持续的血液过滤支持。2018年,肝移植后六天,一名56岁的男性患者被诊断为肠穿孔,随后被修复,他的肠子末端被切除了.患者30天后病情稳定出院。2017年,肾移植后五天,一名46岁的女性患者被诊断为肠穿孔,修复了,穿孔部位保持开放。患者在40天后病情稳定出院。肠穿孔是比较少见的,但并不少见,并发症。由于非特异性临床症状和体征,早期诊断具有挑战性。考虑到肠穿孔的可能性并获得早期腹部计算机断层扫描成像可以帮助防止延迟诊断。
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