目的:本研究的目的是评估术前使用印度墨水(ETI)进行内窥镜纹身对腹腔镜手术治疗I期右侧结肠癌(RCC)期间切除的淋巴结(LN)数量的影响。
方法:这种单中心,回顾性研究纳入2010年1月至2021年12月接受腹腔镜手术的I期RCC患者.比较接受和未接受ETI治疗的患者的临床病理背景和LN数量。使用多元线性回归分析来检查独立变量对LN产量的影响。
结果:共纳入169例患者。其中,89例患者(52.7%)被归入ETI组,80例(47.3%)归入无ETI组。在年龄上没有显著差异,性别,身体质量指数,或两组之间的肿瘤进展。单变量分析表明,女性中检索到的LN数量显着增加(26vs.24,p=0.026),与肿瘤定位在升结肠或横结肠(20在盲肠,26在升结肠,27在横结肠,p<0.001),和术前ETI(28vs.21,p<0.001)。在多元线性回归分析中,女性(p=0.0011),D3淋巴结清扫术(p=0.046),术前ETI(p=0.012)与LN产量独立相关。
结论:在I期肾癌的腹腔镜手术中,术前ETI增加了检索到的LN的数量,并允许进行适当的分期.
OBJECTIVE: The purpose of this study is to evaluate the effect of preoperative endoscopic tattooing using India ink (ETI) on the number of retrieved lymph nodes (LNs) dissected during laparoscopic surgery for stage I right-sided colon cancer (RCC).
METHODS: This single-center, retrospective study included stage I RCC patients who underwent laparoscopic surgery between January 2010 and December 2021. The clinicopathological background and number of LNs retrieved were compared between patients managed with and without ETI. A multiple linear regression analysis was used to examine the effect of independent variables on the LN yield.
RESULTS: A total of 169 patients were enrolled. Of these, 89 patients (52.7%) were classified into the ETI group, and 80 (47.3%) were classified into the no-ETI group. There were no significant differences in age, sex, body mass index, or tumor progression between the two groups. A univariate analysis showed that the number of LNs retrieved was significantly higher in female (26 vs. 24, p = 0.026), with tumor localization in the ascending or transverse colon (20 in the cecum, 26 in the ascending colon, 27 in the transverse colon, p < 0.001), and with preoperative ETI (28 vs. 21, p < 0.001). In a multivariate linear regression analysis, female sex (p = 0.0011), D3 lymphadenectomy (p = 0.046), and preoperative ETI (p = 0.012) were independently associated with the LN yield.
CONCLUSIONS: In laparoscopic surgery for stage I RCC, preoperative ETI increased the number of LNs retrieved and allowed for appropriate staging.