PDF(Pubmed)
Abstract：
Cryptococcosis is a fungal infection that may arise in immunocompromised or immunocompetent individuals. This case report seeks to demonstrate the difficulty in diagnosing and treating cryptococcosis based on clinical presentation and radiographic features as together, they mimic other pathological conditions. A 56-year-old female with cirrhosis presented with persistent abdominal pain, dyspnea, vomiting, and diarrhea and was diagnosed with pulmonary cryptococcosis after an initial diagnosis of bacterial pneumonia. With no improvement following antibiotic therapy for suspected bacterial pneumonia, additional imaging was performed with a confirmatory lung biopsy for pulmonary cryptococcosis. The patient initiated antifungal therapy with the anticipation of completing approximately 12 months with follow-up imaging to evaluate improvement. After the patient experienced adverse effects of antifungal therapy and did not achieve significant improvement or recovery in her condition, it was apparent that cryptococcal pneumonia presents both diagnostic and management challenges that must be further explored.
摘要：
隐球菌病是一种真菌感染，可能发生在免疫功能低下或免疫功能正常的个体中。本病例报告旨在证明根据临床表现和影像学特征共同诊断和治疗隐球菌病的困难。它们模仿其他病理状况。一名56岁的肝硬化女性，表现为持续性腹痛，呼吸困难,呕吐,和腹泻，并在最初诊断为细菌性肺炎后被诊断为肺隐球菌病。疑似细菌性肺炎的抗生素治疗后没有改善，对于肺隐球菌病,我们进行了额外的影像学检查,并进行了确认性肺活检.患者开始抗真菌治疗，预期完成约12个月的随访成像以评估改善情况。在患者经历抗真菌治疗的不良反应后，她的病情没有显著改善或恢复，很明显,隐球菌肺炎在诊断和治疗方面都存在挑战,必须进一步探讨.
